Development Level

Tbio 263 | 11,651
Tchem 40 | 1,388
Tdark 21 | 6,593
Tclin 13 | 612

Collection

RFA-RM-18-021 4 | 328
GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 10 | 499
embryonic lethality prior to t... 9 | 278
abnormal behavior 5 | 298
embryonic lethality prior to o... 5 | 239
increased lean body mass 5 | 172
abnormal bone structure 4 | 187
abnormal seminal vesicle morph... 4 | 114
decreased bone mineral content 4 | 151
decreased bone mineral density 4 | 126
decreased vertical activity 4 | 208
enlarged lymph nodes 4 | 37
hypoactivity 4 | 132
increased bone mineral content 4 | 108
increased bone mineral density 4 | 72
increased circulating alkaline... 4 | 122
short tibia 4 | 97
abnormal embryo size 3 | 220
abnormal kidney morphology 3 | 65
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased mean corpuscular hem... 3 | 50
decreased total body fat amoun... 3 | 207
impaired glucose tolerance 3 | 75
increased circulating sodium l... 3 | 71
increased circulating triglyce... 3 | 42
abnormal coat appearance 2 | 31
abnormal coat-hair pigmentatio... 2 | 64
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal lung morphology 2 | 26
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased caudal vertebrae num... 2 | 53
decreased circulating bilirubi... 2 | 19
decreased circulating calcium ... 2 | 36
decreased circulating glucose ... 2 | 126
decreased food intake 2 | 13
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased threshold for audito... 2 | 26
enlarged heart 2 | 210
hyperactivity 2 | 148
increased circulating aspartat... 2 | 15
increased circulating chloride... 2 | 41
increased circulating creatini... 2 | 38
increased circulating fructosa... 2 | 13
increased circulating magnesiu... 2 | 10
increased circulating potassiu... 2 | 29
increased circulating thyroxin... 2 | 7
increased circulating total pr... 2 | 28
increased erythrocyte cell num... 2 | 39
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased spleen weight 2 | 10
increased total body fat amoun... 2 | 134
prenatal lethality 2 | 28
small spleen 2 | 19
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal locomotor activation 1 | 16
abnormal neural tube closure 1 | 46
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
brachydactyly 1 | 19
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased circulating amylase ... 1 | 28
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 31
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating amylase ... 1 | 25
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased startle reflex 1 | 112
limb grasping 1 | 41
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
stereotypic behavior 1 | 3
syndactyly 1 | 23
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 192 | 11,493
osteosarcoma 173 | 7,950
psoriasis 168 | 6,694
ovarian cancer 156 | 8,520
glioblastoma 123 | 5,792
Cancer 115 | 2,499
medulloblastoma, large-cell 112 | 6,241
lung cancer 106 | 4,740
lung carcinoma 104 | 2,843
Astrocytoma, Pilocytic 90 | 3,081
non-small cell lung cancer 82 | 2,890
atypical teratoid / rhabdoid tumor 81 | 5,112
malignant mesothelioma 81 | 3,232
diabetes mellitus 79 | 1,728
adult high grade glioma 77 | 3,801
ependymoma 75 | 4,679
interstitial cystitis 75 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 75 | 3,291
Rheumatoid arthritis 72 | 1,191
Breast cancer 71 | 3,578
invasive ductal carcinoma 71 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 70 | 2,955
lung adenocarcinoma 70 | 2,716
pancreatic cancer 70 | 2,398
tuberculosis 67 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 66 | 2,989
dermatomyositis 65 | 966
subependymal giant cell astrocytoma 63 | 2,287
Human immunodeficiency virus infectious disease 56 | 138
group 3 medulloblastoma 56 | 4,104
ulcerative colitis 56 | 1,819
Ankylosing spondylitis 52 | 140
Psoriatic arthritis 50 | 86
oligodendroglioma 50 | 2,850
Behcet's disease 49 | 89
Stevens-Johnson syndrome 49 | 92
Arthritis 45 | 290
Hypersensitivity reaction type II disease 45 | 253
pancreatic ductal adenocarcinoma liver metastasis 45 | 1,962
primitive neuroectodermal tumor 45 | 3,035
mucosa-associated lymphoid tissue lymphoma 44 | 484
Dermatitis 43 | 157
Kidney cancer 43 | 2,613
cutaneous lupus erythematosus 43 | 1,057
primary pancreatic ductal adenocarcinoma 41 | 1,109
Multiple myeloma 40 | 1,332
astrocytic glioma 38 | 2,597
astrocytoma 38 | 1,146
Acquired immunodeficiency syndrome 37 | 197
Nephritis 37 | 51
Synovitis 37 | 78
Herpes zoster 36 | 68
Juvenile rheumatoid arthritis 36 | 111
Liver Cirrhosis, Experimental 36 | 769
Pick disease 36 | 1,894
Takayasu's arteritis 36 | 53
Uveitis 36 | 103
juvenile dermatomyositis 36 | 1,187
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
cystic fibrosis 35 | 1,696
drug-induced hepatitis 35 | 44
colon cancer 34 | 1,478
group 4 medulloblastoma 34 | 1,855
Autosomal recessive predisposition 30 | 1,442
Duchenne muscular dystrophy 30 | 601
acute quadriplegic myopathy 30 | 1,158
pediatric high grade glioma 30 | 1,064
gastric carcinoma 29 | 807
Waldenstrons macroglobulinemia 28 | 765
ductal carcinoma in situ 28 | 1,745
adrenocortical carcinoma 27 | 1,428
breast carcinoma 26 | 1,638
spina bifida 25 | 1,074
nasopharyngeal carcinoma 24 | 1,058
pituitary cancer 24 | 1,972
primary Sjogren syndrome 24 | 735
Alzheimer's disease 23 | 658
active Crohn's disease 23 | 922
esophageal adenocarcinoma 23 | 737
Schizophrenia 22 | 1,160
non primary Sjogren syndrome sicca 22 | 891
active ulcerative colitis 20 | 764
acute myeloid leukemia 20 | 783
Kidney disease 19 | 430
Anemia 18 | 365
Asthma 18 | 385
Multiple Sclerosis 18 | 540
Atopic dermatitis 17 | 952
Neurodegenerative disease 17 | 414
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 510
head and neck cancer and chronic obstructive pulmonary disease 16 | 239
pancreatic carcinoma 16 | 562
Bipolar Disorder 15 | 666
Down syndrome 15 | 499
Epilepsy 15 | 792
Melanoma 15 | 711
hepatocellular carcinoma 15 | 547

Tissue

Endocrine System 285 | 18,159
Digestive Tract 280 | 17,369
Female tissues 280 | 17,400
Blood and immune system 279 | 16,909
Skin and soft tissues 279 | 17,230
Liver and Pancreas 276 | 16,750
Male tissues 276 | 17,142
Respiratory system 275 | 16,393
Urinary Tract 272 | 16,678
Nervous System 269 | 16,725
Cardiovascular System 253 | 15,192

Target Family

Non-IDG 211 | 12,091
Enzyme 86 | 4,145
Transporter 18 | 473
GPCR 11 | 408
Ion Channel 10 | 344
Kinase 1 | 634

Compartment GO Term

Secretory granule membrane 337 | 337
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein disulfide-isomerase TMX3 TMX3 Tbio Enzyme -0.72922 5.29 80
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Equatorin EQTN Tdark Non-IDG -1.22168 17.0 17
Desmoglein-1 DSG1 Tbio Non-IDG -2.72159 516.2 406
Coatomer subunit beta COPB1 Tbio Non-IDG -1.94049 82.6 148
Ras-related protein Rab-40A RAB40A Tdark Non-IDG -0.72564 4.56 104
HLA class I histocompatibility antigen, B-37 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Rho-related GTP-binding protein RhoN RND2 Tbio Enzyme -1.51649 30.9 69
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.79654 64.6 107
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100