Development Level

Tbio 49 | 10,625
Tdark 10 | 7,003
Tchem 9 | 1,890
Tclin 4 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

abnormal behavior 2 | 226
abnormal coat/hair pigmentatio... 2 | 54
cataract 2 | 26
decreased bone mineral content 2 | 157
decreased circulating LDL chol... 2 | 37
embryonic lethality prior to t... 2 | 187
hypoactivity 2 | 89
increased erythrocyte cell num... 2 | 26
increased hemoglobin content 2 | 45
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 2
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placement of pupils 1 | 4
abnormal posture 1 | 5
abnormal respiratory quotient 1 | 9
abnormal response to new envir... 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal snout morphology 1 | 18
abnormal testis morphology 1 | 30
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased food intake 1 | 6
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 19
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
enlarged heart 1 | 111
enlarged liver 1 | 3
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased circulating amylase ... 1 | 13
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating fructosa... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
male infertility 1 | 62
microcephaly 1 | 3
narrow eye opening 1 | 15
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
small epididymis 1 | 3
small testis 1 | 37
tremors 1 | 34

Disease

osteosarcoma 39 | 7,933
ovarian cancer 34 | 8,484
glioblastoma 32 | 5,572
psoriasis 30 | 6,685
medulloblastoma, large-cell 29 | 6,234
lung cancer 26 | 4,466
pilocytic astrocytoma 25 | 3,086
pancreatic cancer 23 | 2,300
pediatric high grade glioma 22 | 2,712
atypical teratoid / rhabdoid tumor 21 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,289
lung carcinoma 21 | 2,844
malignant mesothelioma 21 | 3,162
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
invasive ductal carcinoma 18 | 2,950
lung adenocarcinoma 18 | 2,713
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
oligodendroglioma 16 | 2,849
primitive neuroectodermal tumor 16 | 3,031
primary pancreatic ductal adenocarcinoma 15 | 1,271
subependymal giant cell astrocytoma 15 | 2,287
interstitial cystitis 14 | 2,299
non-small cell lung cancer 14 | 2,798
Breast cancer 13 | 3,094
Multiple myeloma 13 | 1,327
tuberculosis 13 | 1,557
Cancer 12 | 2,346
group 4 medulloblastoma 12 | 1,875
ulcerative colitis 12 | 2,087
colon cancer 11 | 1,475
ependymoma 11 | 2,514
Carcinoma 10 | 2,147
Pick disease 10 | 1,893
astrocytoma 10 | 1,493
cutaneous lupus erythematosus 9 | 1,056
diabetes mellitus 9 | 1,663
ductal carcinoma in situ 9 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
posterior fossa group A ependymoma 9 | 1,511
Rheumatoid Arthritis 8 | 1,160
Waldenstrons macroglobulinemia 8 | 765
adrenocortical carcinoma 8 | 1,427
adult high grade glioma 8 | 2,148
astrocytic glioma 8 | 2,241
cystic fibrosis 8 | 1,665
juvenile dermatomyositis 8 | 1,189
Duchenne muscular dystrophy 7 | 602
Obesity 7 | 616
medulloblastoma 7 | 1,524
pancreatic carcinoma 7 | 567
posterior fossa group B ependymoma 7 | 1,530
Atopic dermatitis 6 | 944
esophageal adenocarcinoma 6 | 737
gastric cancer 6 | 430
gastric carcinoma 6 | 832
group 3 medulloblastoma 6 | 2,254
pituitary cancer 6 | 1,972
primary Sjogren syndrome 6 | 789
sonic hedgehog group medulloblastoma 6 | 1,482
Alzheimer's disease 5 | 644
Asthma 5 | 349
Myocardial Ischemia 5 | 169
Peripheral Neuropathy 5 | 303
Prostatic Neoplasms 5 | 471
acute quadriplegic myopathy 5 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
breast carcinoma 5 | 1,614
dermatomyositis 5 | 933
head and neck cancer 5 | 270
spina bifida 5 | 1,064
Bipolar Disorder 4 | 266
Botulism 4 | 20
Colorectal Neoplasms 4 | 217
Coronary artery disease 4 | 240
Crohn's disease 4 | 304
Down syndrome 4 | 548
Heart disease 4 | 279
IGA Glomerulonephritis 4 | 454
Infertility 4 | 163
Multiple Sclerosis 4 | 498
Parkinson's disease 4 | 364
Tetanus 4 | 66
Thrombocytopenia 4 | 105
active Crohn's disease 4 | 918
aldosterone-producing adenoma 4 | 664
hereditary spastic paraplegia 4 | 313
mucosa-associated lymphoid tissue lymphoma 4 | 480
progressive supranuclear palsy 4 | 674
Attention deficit hyperactivity disorder 3 | 156
Cerebrovascular disease 3 | 231
Juvenile arthritis 3 | 124
Toxic encephalopathy 3 | 131
acute myeloid leukemia 3 | 780
atypical teratoid/rhabdoid tumor 3 | 1,095
chronic rhinosinusitis 3 | 512
fibroadenoma 3 | 557
hepatocellular carcinoma 3 | 532
inflammatory breast cancer 3 | 404
nasopharyngeal carcinoma 3 | 1,056
urothelial carcinoma 3 | 318

Tissue

Digestive Tract 72 | 18,473
Endocrine System 72 | 18,512
Liver and Pancreas 72 | 18,136
Nervous System 72 | 18,561
Female tissues 71 | 18,647
Skin and soft tissues 71 | 18,115
Urinary Tract 71 | 18,444
Cardiovascular System 70 | 17,958
Male tissues 70 | 17,969
Respiratory system 70 | 17,484
Blood and immune system 69 | 17,995

Target Family

Non-IDG 43 | 11,971
Enzyme 18 | 4,146
Transporter 8 | 473
Ion Channel 3 | 341

Compartment GO Term

Secretory granule membrane 72 | 72
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b561 CYB561 Tbio Non-IDG -1.41910 20.4 45
Transmembrane protein 184A TMEM184A Tdark Non-IDG -0.20412 2.16 46
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.51989 315.7 757
Phosphatase and actin regulator 2 PHACTR2 Tbio Enzyme -0.48667 0.00000 71
Multidrug resistance-associated protein 4 ABCC4 Tbio Transporter -2.50986 316.0 288
Zinc transporter 8 SLC30A8 Tbio Transporter -2.13184 153.6 103
Acrosin-binding protein ACRBP Tbio Non-IDG -1.68341 49.3 61
Vesicle-associated membrane protein 7 VAMP7 Tbio Non-IDG -1.83769 81.7 133
Membrane cofactor protein CD46 Tbio Non-IDG -2.90635 849.0 564
Carboxypeptidase E CPE Tbio Enzyme -2.97987 983.1 216