Development Level

Tbio 228 | 11,651
Tchem 64 | 1,388
Tdark 21 | 6,593
Tclin 16 | 612

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 15 | 499
decreased vertical activity 6 | 208
enlarged heart 6 | 210
abnormal heart morphology 4 | 162
abnormal seminal vesicle morph... 4 | 114
cataract 4 | 92
edema 4 | 59
hypoactivity 4 | 132
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal retina morphology 3 | 71
decreased circulating choleste... 3 | 93
increased or absent threshold ... 3 | 101
male infertility 3 | 123
abnormal coat-hair pigmentatio... 2 | 64
abnormal eye morphology 2 | 68
abnormal humerus morphology 2 | 11
abnormal lens morphology 2 | 81
abnormal retinal vasculature m... 2 | 27
abnormal testis morphology 2 | 43
decreased circulating insulin ... 2 | 76
decreased circulating sodium l... 2 | 22
decreased circulating total pr... 2 | 49
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased mean corpuscular hem... 2 | 31
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased circulating sodium l... 2 | 71
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
increased total body fat amoun... 2 | 134
premature death 2 | 5
short tibia 2 | 97
abnormal QT variability 1 | 10
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal response to novel obj... 1 | 1
abnormal retinal blood vessel ... 1 | 26
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased fluid intake 1 | 3
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
long tibia 1 | 25
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
small adrenal glands 1 | 16
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

ovarian cancer 187 | 8,519
Carcinoma 182 | 11,493
osteosarcoma 170 | 7,950
psoriasis 146 | 6,694
lung cancer 137 | 4,740
Cancer 129 | 2,499
glioblastoma 121 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 98 | 3,290
medulloblastoma, large-cell 95 | 6,241
Breast cancer 86 | 3,577
atypical teratoid / rhabdoid tumor 85 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 85 | 2,954
ependymoma 83 | 4,679
malignant mesothelioma 83 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 82 | 2,988
lung carcinoma 82 | 2,843
lung adenocarcinoma 81 | 2,716
diabetes mellitus 79 | 1,728
pancreatic cancer 78 | 2,398
invasive ductal carcinoma 76 | 2,950
tuberculosis 75 | 2,010
non-small cell lung cancer 74 | 2,890
interstitial cystitis 70 | 2,312
Astrocytoma, Pilocytic 69 | 3,081
pancreatic ductal adenocarcinoma liver metastasis 68 | 1,962
subependymal giant cell astrocytoma 67 | 2,287
adult high grade glioma 65 | 3,801
Autosomal recessive predisposition 61 | 1,442
group 3 medulloblastoma 60 | 4,104
ulcerative colitis 60 | 1,819
Multiple myeloma 55 | 1,332
Waldenstrons macroglobulinemia 53 | 765
cystic fibrosis 51 | 1,695
Liver Cirrhosis, Experimental 50 | 769
breast carcinoma 47 | 1,637
oligodendroglioma 46 | 2,850
acute quadriplegic myopathy 43 | 1,158
pituitary cancer 43 | 1,972
Kidney disease 42 | 430
Schizophrenia 42 | 1,160
primitive neuroectodermal tumor 42 | 3,035
juvenile dermatomyositis 41 | 1,187
astrocytoma 40 | 1,146
mucosa-associated lymphoid tissue lymphoma 40 | 484
primary pancreatic ductal adenocarcinoma 40 | 1,108
astrocytic glioma 39 | 2,597
cutaneous lupus erythematosus 39 | 1,057
ductal carcinoma in situ 39 | 1,744
Kidney cancer 38 | 2,613
esophageal adenocarcinoma 38 | 737
Atopic dermatitis 37 | 952
Duchenne muscular dystrophy 36 | 601
adrenocortical carcinoma 36 | 1,428
colon cancer 36 | 1,478
Pick disease 35 | 1,894
dermatomyositis 35 | 966
Arthritis 34 | 290
Rheumatoid arthritis 34 | 1,191
group 4 medulloblastoma 33 | 1,855
Alzheimer's disease 32 | 658
Atherosclerosis 32 | 291
Hypertension 32 | 396
Vascular disease 32 | 319
Obesity 31 | 678
gastric carcinoma 31 | 807
Liver disease 29 | 237
Lung disease 29 | 142
Hypertensive disease 27 | 292
Seizures 27 | 596
Chemical and Drug Induced Liver Injury 26 | 195
Intellectual disability 26 | 1,016
Coronary artery disease 25 | 268
Epilepsy 24 | 792
Hepatomegaly 24 | 285
active ulcerative colitis 24 | 764
Cerebrovascular disease 23 | 238
Prostatic Neoplasms 23 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 23 | 510
nasopharyngeal carcinoma 23 | 1,058
pancreatic carcinoma 23 | 562
Asthma 22 | 385
Osteoporosis 22 | 363
active Crohn's disease 22 | 922
non primary Sjogren syndrome sicca 22 | 891
primary Sjogren syndrome 22 | 735
Dull intelligence 21 | 645
Low intelligence 21 | 645
Mental Retardation 21 | 645
Mental deficiency 21 | 645
Neoplasm Invasiveness 21 | 161
Poor school performance 21 | 645
Splenomegaly 21 | 190
fibroadenoma 21 | 559
Breast Neoplasms 20 | 445
Carcinoma, Hepatocellular 20 | 228
Heart disease 20 | 306
Liver carcinoma 20 | 240
Mammary Neoplasms 20 | 425
gastric cancer 20 | 459
pediatric high grade glioma 20 | 1,064

Tissue

Female tissues 318 | 17,400
Skin and soft tissues 317 | 17,230
Digestive Tract 316 | 17,369
Liver and Pancreas 316 | 16,750
Endocrine System 315 | 18,159
Blood and immune system 313 | 16,909
Urinary Tract 312 | 16,678
Respiratory system 309 | 16,393
Male tissues 306 | 17,142
Nervous System 301 | 16,725
Cardiovascular System 295 | 15,192

Target Family

Non-IDG 197 | 12,091
Enzyme 117 | 4,145
Kinase 13 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Secretory granule lumen 329 | 329
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Sperm acrosome-associated protein 7 SPACA7 Tdark Non-IDG -0.30103 2.00 31
Cysteine-rich secretory protein 3 CRISP3 Tbio Non-IDG -1.58618 43.2 129
Secreted phosphoprotein 24 SPP2 Tbio Non-IDG -1.20992 21.1 29
Peroxiredoxin-4 PRDX4 Tbio Non-IDG -2.02710 109.0 300
Testis-expressed protein 264 TEX264 Tdark Non-IDG 1.18 0.07 70
Drebrin-like protein DBNL Tbio Non-IDG -1.16567 21.1 172
ATP-dependent 6-phosphofructokinase, liver type PFKL Tbio Kinase -2.07015 107.6 240