Development Level

Tbio 7 | 10,625

IMPC Phenotype

abnormal behavior 1 | 226
abnormal gait 1 | 51
abnormal retina morphology 1 | 100
decreased mean corpuscular vol... 1 | 50
decreased startle reflex 1 | 48
hyperactivity 1 | 108
limb grasping 1 | 35

Disease

ovarian cancer 6 | 8,491
medulloblastoma, large-cell 5 | 6,234
osteosarcoma 5 | 7,933
atypical teratoid / rhabdoid tumor 4 | 4,369
glioblastoma 4 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
invasive ductal carcinoma 4 | 2,950
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pediatric high grade glioma 4 | 2,712
psoriasis 4 | 6,685
Multiple myeloma 3 | 1,327
Waldenstrons macroglobulinemia 3 | 764
astrocytic glioma 3 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
non-small cell lung cancer 3 | 2,798
pancreatic cancer 3 | 2,300
primitive neuroectodermal tumor 3 | 3,031
subependymal giant cell astrocytoma 3 | 2,287
ependymoma 2 | 2,514
group 4 medulloblastoma 2 | 1,875
interstitial cystitis 2 | 2,299
lung cancer 2 | 4,473
oligodendroglioma 2 | 2,849
pilocytic astrocytoma 2 | 3,086
sonic hedgehog group medulloblastoma 2 | 1,482
Acquired metabolic disease 1 | 267
Amyotrophic lateral sclerosis type 8 1 | 9
Breast cancer 1 | 3,098
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Iy 1 | 1
Congenital disorder of glycosylation 1 | 53
Congenital disorder of glycosylation 1Y 1 | 1
Craniofacial Abnormalities 1 | 147
Cryptosporidiosis 1 | 12
Familial encephalopathy with neuroserpin inclusion bodies 1 | 8
Gaucher disease type 1 1 | 171
Giardiasis 1 | 10
Isolated polycystic liver disease 1 | 3
Microphthalmia 1 | 79
Microsporidiosis 1 | 12
Neurodegenerative disease 1 | 383
Pick disease 1 | 1,893
Polycystic Kidney Diseases 1 | 3
Polycystic Ovary Syndrome 1 | 334
Polycystic kidney disease 1 | 54
Polycystic liver disease 1 | 10
Polycystic liver disease 2 1 | 1
Prostatic Neoplasms 1 | 471
Rheumatoid Arthritis 1 | 1,170
Small intestine carcinoma 1 | 1
Spastic paraplegia 61, autosomal recessive 1 | 1
active Crohn's disease 1 | 918
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
adult high grade glioma 1 | 2,148
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
autosomal dominant polycystic kidney disease 1 | 2
dermatomyositis 1 | 966
esophageal adenocarcinoma 1 | 737
gastric cancer 1 | 436
glioblastoma multiforme 1 | 347
hepatocellular carcinoma 1 | 550
hereditary spastic paraplegia 1 | 313
hereditary spastic paraplegia 61 1 | 1
lung adenocarcinoma 1 | 2,714
lung carcinoma 1 | 2,844
malignant mesothelioma 1 | 3,163
medulloblastoma 1 | 1,524
non primary Sjogren syndrome sicca 1 | 840
pancreatic carcinoma 1 | 567
periodontitis 1 | 269
permanent atrial fibrillation 1 | 44
posterior fossa group A ependymoma 1 | 1,511
primary pancreatic ductal adenocarcinoma 1 | 1,271
spina bifida 1 | 1,064
tuberculosis 1 | 1,563
tuberculosis and treatment for 3 months 1 | 327
tuberculosis and treatment for 6 months 1 | 686
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 7 | 17,994
Cardiovascular System 7 | 17,957
Digestive Tract 7 | 18,472
Endocrine System 7 | 18,511
Female tissues 7 | 18,646
Liver and Pancreas 7 | 18,135
Male tissues 7 | 17,968
Nervous System 7 | 18,560
Respiratory system 7 | 17,483
Skin and soft tissues 7 | 18,114
Urinary Tract 7 | 18,443

Target Family

Non-IDG 6 | 11,969
Enzyme 1 | 4,146

Compartment GO Term

Sec61 translocon complex 7 | 7
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein transport protein Sec61 subunit alpha isoform 1 SEC61A1 Tbio Non-IDG -2.45216 280.2 94
ADP-ribosylation factor-like protein 6-interacting protein 1 ARL6IP1 Tbio Non-IDG -1.00354 13.7 174
Translocon-associated protein subunit delta SSR4 Tbio Non-IDG -1.01463 10.3 81
DnaJ homolog subfamily B member 9 DNAJB9 Tbio Non-IDG -2.05906 117.2 153
E3 ubiquitin-protein ligase MARCH6 MARCH6 Tbio Enzyme -1.64458 43.9 115
Translocation protein SEC63 homolog SEC63 Tbio Non-IDG -1.81045 60.2 85
Translocation protein SEC62 SEC62 Tbio Non-IDG -1.72172 48.9 94