Development Level

Tbio 33 | 11,445
Tclin 12 | 613
Tchem 10 | 1,598
Tdark 3 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
edema 2 | 59
increased leukocyte cell numbe... 2 | 47
abnormal facial morphology 1 | 17
abnormal placenta vasculature 1 | 2
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal sensory capabilities-... 1 | 8
abnormal urinary bladder morph... 1 | 11
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased vertical activity 1 | 24
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2
small epididymis 1 | 3

Disease

Carcinoma 36 | 11,493
medulloblastoma, large-cell 32 | 6,241
osteosarcoma 29 | 7,950
psoriasis 29 | 6,694
glioblastoma 28 | 5,792
group 3 medulloblastoma 28 | 4,104
atypical teratoid / rhabdoid tumor 27 | 5,112
ependymoma 25 | 4,679
ovarian cancer 24 | 8,520
primitive neuroectodermal tumor 23 | 3,035
Astrocytoma, Pilocytic 22 | 3,081
adult high grade glioma 22 | 3,801
lung cancer 21 | 4,740
Breast cancer 19 | 3,578
astrocytic glioma 19 | 2,597
oligodendroglioma 17 | 2,850
Kidney cancer 16 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
lung carcinoma 16 | 2,843
Heart disease 15 | 306
lung adenocarcinoma 15 | 2,716
Malignant hyperthermia 14 | 26
Autosomal recessive predisposition 13 | 1,442
colon cancer 13 | 1,478
pancreatic cancer 13 | 2,398
cystic fibrosis 12 | 1,696
subependymal giant cell astrocytoma 12 | 2,287
Liver cancer 11 | 604
acute quadriplegic myopathy 11 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
malignant mesothelioma 11 | 3,232
Epilepsy 10 | 792
Hypertension 10 | 396
Pick disease 10 | 1,894
pituitary cancer 10 | 1,972
tuberculosis 10 | 2,010
Cancer 9 | 2,499
Myopathy 9 | 185
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
non-small cell lung cancer 9 | 2,890
Schizophrenia 8 | 1,160
diabetes mellitus 8 | 1,728
invasive ductal carcinoma 8 | 2,951
juvenile dermatomyositis 8 | 1,187
Endometrial cancer 7 | 311
Primary cutaneous amyloidosis 7 | 29
Seizures 7 | 596
Ventricular arrhythmia 7 | 27
Atopic dermatitis 6 | 952
Proximal muscle weakness 6 | 47
Proximal neurogenic muscle weakness 6 | 47
Rheumatoid arthritis 6 | 1,191
active ulcerative colitis 6 | 764
ductal carcinoma in situ 6 | 1,745
interstitial cystitis 6 | 2,312
ulcerative colitis 6 | 1,819
Amyotrophic lateral sclerosis 5 | 451
Atrial Fibrillation 5 | 124
Cardiac Arrhythmia 5 | 103
Catecholaminergic polymorphic ventricular tachycardia 5 | 12
Cerebrovascular disease 5 | 238
Creatine phosphokinase serum increased 5 | 110
Elevated creatine kinase 5 | 110
Heart failure 5 | 162
Large intestine cancer 5 | 126
Liver Cirrhosis, Experimental 5 | 769
Muscle hypotonia 5 | 571
Myocardial Ischemia 5 | 169
Obesity 5 | 678
Sudden death 5 | 16
dermatomyositis 5 | 966
non primary Sjogren syndrome sicca 5 | 891
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Cardiomyopathy 4 | 116
Cardiomyopathy, Dilated 4 | 83
DOID:2627 4 | 94
Dizziness 4 | 26
Heart conduction disease 4 | 83
Hypertensive disorder 4 | 56
Hypertrophic Cardiomyopathy 4 | 117
Long QT syndrome 1 4 | 20
Melanoma 4 | 711
Multiple myeloma 4 | 1,332
Muscle Cramp 4 | 55
Muscle Weakness 4 | 170
Myocardial Infarction 4 | 151
Myocardial Reperfusion Injury 4 | 37
Renal Cell Carcinoma 4 | 214
Skin cancer 4 | 469
Syncope 4 | 22
Tetanus 4 | 68
Toxic encephalopathy 4 | 141
Vertigo 4 | 29
active Crohn's disease 4 | 922
breast carcinoma 4 | 1,638
chronic rhinosinusitis 4 | 512
pancreatic carcinoma 4 | 562
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064

Tissue

Digestive Tract 58 | 17,369
Endocrine System 58 | 18,159
Female tissues 58 | 17,400
Male tissues 58 | 17,142
Skin and soft tissues 58 | 17,230
Blood and immune system 56 | 16,909
Nervous System 56 | 16,725
Respiratory system 56 | 16,393
Urinary Tract 56 | 16,678
Liver and Pancreas 54 | 16,750
Cardiovascular System 52 | 15,192

Target Family

Non-IDG 23 | 12,091
Ion Channel 12 | 344
Enzyme 11 | 4,145
Kinase 5 | 634
Transporter 5 | 473
GPCR 1 | 408
Transcription Factor 1 | 1,400

Compartment GO Term

Sarcoplasmic reticulum membran... 58 | 58
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctophilin-3 JPH3 Tbio Non-IDG -1.51901 34.8 165
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Junctophilin-1 JPH1 Tbio Non-IDG -1.77250 56.2 92
Junctophilin-2 JPH2 Tbio Non-IDG -2.21890 163.0 229
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Calcium homeostasis endoplasmic reticulum protein CHERP Tbio Non-IDG -0.83990 7.33 159
Nucleoporin GLE1 GLE1 Tbio Non-IDG -2.24700 173.6 150