Development Level

Tbio 53 | 10,625
Tchem 17 | 1,890
Tclin 11 | 602
Tdark 3 | 7,003

Collection

Eligible Ion Channel Proteins 2 | 117

IMPC Term

preweaning lethality, complete... 10 | 633
embryonic lethality prior to t... 4 | 187
abnormal embryo size 3 | 112
abnormal retina morphology 3 | 100
abnormal behavior 2 | 226
decreased eosinophil cell numb... 2 | 41
decreased lean body mass 2 | 195
hyperactivity 2 | 108
increased body length 2 | 20
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased lean body mass 2 | 107
abnormal epididymis morphology 1 | 31
abnormal facial morphology 1 | 9
abnormal forebrain development 1 | 18
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal liver morphology 1 | 5
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta vasculature 1 | 2
abnormal response to new envir... 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal retinal outer nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal seminal vesicle morph... 1 | 47
abnormal sensory capabilities/... 1 | 3
abnormal skin morphology 1 | 23
abnormal thoracic vertebrae mo... 1 | 16
abnormal urinary bladder morph... 1 | 2
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 35
corneal vascularization 1 | 5
cyanosis 1 | 6
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating amylase ... 1 | 24
decreased circulating bilirubi... 1 | 14
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating triglyce... 1 | 83
decreased heart rate variabili... 1 | 11
decreased prepulse inhibition 1 | 52
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
edema 1 | 11
enlarged epididymis 1 | 27
enlarged heart 1 | 111
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased B cell number 1 | 23
increased NK T cell number 1 | 11
increased T cell number 1 | 15
increased circulating alkaline... 1 | 119
increased circulating total pr... 1 | 20
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased gamma-delta T cell n... 1 | 16
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
limb grasping 1 | 35
prenatal lethality 1 | 16
preweaning lethality, incomple... 1 | 260
respiratory system phenotype 1 | 2
small epididymis 1 | 3
straub tail 1 | 26
thick ventricular wall 1 | 7

Disease

medulloblastoma, large-cell 44 | 6,234
glioblastoma 43 | 5,572
osteosarcoma 40 | 7,933
psoriasis 40 | 6,685
ovarian cancer 31 | 8,484
pilocytic astrocytoma 30 | 3,086
primitive neuroectodermal tumor 29 | 3,031
atypical teratoid / rhabdoid tumor 28 | 4,369
lung cancer 27 | 4,466
Carcinoma 26 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
ependymoma 22 | 2,514
lung carcinoma 22 | 2,844
astrocytic glioma 21 | 2,241
lung adenocarcinoma 21 | 2,713
pediatric high grade glioma 21 | 2,712
Breast cancer 20 | 3,094
Heart disease 20 | 279
oligodendroglioma 20 | 2,849
cystic fibrosis 19 | 1,665
group 3 medulloblastoma 19 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
Cancer 18 | 2,346
adult high grade glioma 18 | 2,148
colon cancer 18 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
malignant mesothelioma 17 | 3,162
subependymal giant cell astrocytoma 17 | 2,287
acute quadriplegic myopathy 16 | 1,157
pancreatic cancer 16 | 2,300
pituitary cancer 16 | 1,972
diabetes mellitus 14 | 1,663
invasive ductal carcinoma 14 | 2,950
ulcerative colitis 14 | 2,087
Hypertension 13 | 287
Malignant hyperthermia 13 | 25
Myopathy 13 | 128
Pick disease 13 | 1,893
sonic hedgehog group medulloblastoma 13 | 1,482
atypical teratoid/rhabdoid tumor 12 | 1,095
Schizophrenia 11 | 501
Obesity 10 | 616
Primary cutaneous amyloidosis 10 | 26
astrocytoma 10 | 1,493
juvenile dermatomyositis 10 | 1,189
non-small cell lung cancer 10 | 2,798
posterior fossa group A ependymoma 10 | 1,511
Kidney disease 9 | 396
Long QT syndrome 9 | 52
group 4 medulloblastoma 9 | 1,875
interstitial cystitis 9 | 2,299
tuberculosis 9 | 1,557
Cerebrovascular disease 8 | 231
Duchenne muscular dystrophy 8 | 602
Myocardial Ischemia 8 | 169
Neurodegenerative disease 8 | 383
Rheumatoid Arthritis 8 | 1,160
ductal carcinoma in situ 8 | 1,745
Alzheimer's disease 7 | 644
Amyotrophic Lateral Sclerosis 7 | 431
Coronary artery disease 7 | 240
adrenocortical carcinoma 7 | 1,427
breast carcinoma 7 | 1,614
medulloblastoma 7 | 1,524
pancreatic carcinoma 7 | 567
posterior fossa group B ependymoma 7 | 1,530
Atopic dermatitis 6 | 944
Bipolar Disorder 6 | 266
Cardiomegaly 6 | 66
Cardiomyopathy 6 | 110
Epilepsy 6 | 346
Heart failure 6 | 80
Hypertensive disease 6 | 193
Hypertrophic Cardiomyopathy 6 | 56
Hypokalemia 6 | 40
Multiple myeloma 6 | 1,327
Neuropathy 6 | 210
active Crohn's disease 6 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
dermatomyositis 6 | 933
non primary Sjogren syndrome sicca 6 | 840
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
primary pancreatic ductal adenocarcinoma 6 | 1,271
spina bifida 6 | 1,064
Anemia 5 | 252
Atrial Fibrillation 5 | 110
Chronic Lymphocytic Leukemia 5 | 242
Diabetes Mellitus, Non-Insulin-Dependent 5 | 157
Heart conduction disease 5 | 65
Kidney cancer 5 | 118
Myocardial Infarction 5 | 126
Myocardial Reperfusion Injury 5 | 34
Polycystic Ovary Syndrome 5 | 332
Renal Cell Carcinoma 5 | 199
interstitial lung disease 5 | 291
nasopharyngeal carcinoma 5 | 1,056
non-small cell lung carcinoma 5 | 413
Becker muscular dystrophy 4 | 187
esophageal adenocarcinoma 4 | 737
mucosa-associated lymphoid tissue lymphoma 4 | 480

Tissue

Cardiovascular System 84 | 17,958
Digestive Tract 84 | 18,473
Endocrine System 84 | 18,512
Female tissues 84 | 18,647
Liver and Pancreas 84 | 18,136
Nervous System 84 | 18,561
Skin and soft tissues 84 | 18,115
Urinary Tract 84 | 18,444
Blood and immune system 83 | 17,995
Male tissues 83 | 17,969
Respiratory system 82 | 17,484

Target Family

Non-IDG 43 | 11,971
Enzyme 16 | 4,146
Ion Channel 13 | 341
Kinase 5 | 634
Transporter 5 | 473
GPCR 1 | 406
TF/Epigenetic 1 | 38

Compartment GO Term

Sarcoplasmic reticulum 84 | 84
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cardiac phospholamban PLN Tbio Non-IDG -1.89899 84.7 326
Calumenin CALU Tbio Non-IDG -1.76431 61.4 157
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Calcium homeostasis endoplasmic reticulum protein CHERP Tbio Non-IDG -0.65642 6.28 151
Peptidyl-prolyl cis-trans isomerase FKBP1A FKBP1A Tclin Enzyme -2.75744 370.6 255
Sarcoplasmic reticulum histidine-rich calcium-binding protein HRC Tbio Non-IDG -2.29405 210.5 51
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein NOS1AP Tbio Enzyme -2.09236 133.4 142
60S ribosomal protein L37a RPL37A Tbio Non-IDG -1.47528 30.8 63
Protein S100-A1 S100A1 Tbio Non-IDG -2.44452 281.9 501
Membrane transport protein XK XK Tbio Non-IDG -4.91542 83211.2 112