Development Level

Tbio 56 | 11,445
Tchem 15 | 1,598
Tclin 13 | 613
Tdark 3 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal embryo size 4 | 220
embryonic lethality prior to t... 4 | 278
decreased prepulse inhibition 2 | 82
edema 2 | 59
hyperactivity 2 | 148
increased leukocyte cell numbe... 2 | 47
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal facial morphology 1 | 17
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal placenta vasculature 1 | 2
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal urinary bladder morph... 1 | 11
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
corneal vascularization 1 | 6
cyanosis 1 | 7
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased fluid intake 1 | 3
decreased heart rate variabili... 1 | 13
decreased mean platelet volume 1 | 25
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
mammalian phenotype 1 | 17
prenatal lethality 1 | 28
respiratory system phenotype 1 | 2
small epididymis 1 | 3

Disease

Carcinoma 51 | 11,493
glioblastoma 44 | 5,792
medulloblastoma, large-cell 44 | 6,241
osteosarcoma 40 | 7,950
psoriasis 40 | 6,694
atypical teratoid / rhabdoid tumor 39 | 5,112
group 3 medulloblastoma 38 | 4,104
ependymoma 37 | 4,679
adult high grade glioma 34 | 3,801
ovarian cancer 33 | 8,520
Astrocytoma, Pilocytic 31 | 3,081
Breast cancer 29 | 3,578
lung cancer 29 | 4,740
primitive neuroectodermal tumor 29 | 3,035
Kidney cancer 26 | 2,613
astrocytic glioma 25 | 2,597
Heart disease 22 | 306
lung adenocarcinoma 22 | 2,716
lung carcinoma 22 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Cancer 20 | 2,499
oligodendroglioma 20 | 2,850
Autosomal recessive predisposition 19 | 1,442
colon cancer 19 | 1,478
cystic fibrosis 19 | 1,696
malignant mesothelioma 19 | 3,232
pancreatic cancer 19 | 2,398
Hypertension 18 | 396
acute quadriplegic myopathy 17 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
subependymal giant cell astrocytoma 17 | 2,287
diabetes mellitus 16 | 1,728
pituitary cancer 16 | 1,972
Schizophrenia 15 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
invasive ductal carcinoma 15 | 2,951
Liver cancer 14 | 604
Malignant hyperthermia 14 | 26
Epilepsy 13 | 792
Myopathy 13 | 185
Pick disease 13 | 1,894
non-small cell lung cancer 12 | 2,890
tuberculosis 12 | 2,010
Bipolar Disorder 10 | 666
Cerebrovascular disease 10 | 238
Hypertensive disease 10 | 292
interstitial cystitis 10 | 2,312
juvenile dermatomyositis 10 | 1,187
Alzheimer's disease 9 | 658
Heart failure 9 | 162
Kidney disease 9 | 430
Myocardial Ischemia 9 | 169
Obesity 9 | 678
Primary cutaneous amyloidosis 9 | 29
Seizures 9 | 596
ductal carcinoma in situ 9 | 1,745
ulcerative colitis 9 | 1,819
Anemia 8 | 365
Cardiac Arrhythmia 8 | 103
Duchenne muscular dystrophy 8 | 601
Endometrial cancer 8 | 311
Myocardial Infarction 8 | 151
Rheumatoid arthritis 8 | 1,191
Ventricular arrhythmia 8 | 27
active ulcerative colitis 8 | 764
breast carcinoma 8 | 1,638
Atrial Fibrillation 7 | 124
Cardiomegaly 7 | 116
Cardiomyopathy 7 | 116
Coronary artery disease 7 | 268
Liver Cirrhosis, Experimental 7 | 769
Melanoma 7 | 711
Neuropathy 7 | 261
Sudden death 7 | 16
adrenocortical carcinoma 7 | 1,428
Amyotrophic lateral sclerosis 6 | 451
Atopic dermatitis 6 | 952
Creatine phosphokinase serum increased 6 | 110
Elevated creatine kinase 6 | 110
Hypertrophic Cardiomyopathy 6 | 117
Large intestine cancer 6 | 126
Multiple myeloma 6 | 1,332
Muscle hypotonia 6 | 571
Myocardial Reperfusion Injury 6 | 37
Neurodegenerative disease 6 | 414
Proximal muscle weakness 6 | 47
Proximal neurogenic muscle weakness 6 | 47
Skin cancer 6 | 469
active Crohn's disease 6 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
dermatomyositis 6 | 966
group 4 medulloblastoma 6 | 1,855
non primary Sjogren syndrome sicca 6 | 891
pancreatic carcinoma 6 | 562
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
primary pancreatic ductal adenocarcinoma 6 | 1,109
Depressive disorder 5 | 409
astrocytoma 5 | 1,146
spina bifida 5 | 1,074

Tissue

Digestive Tract 87 | 17,369
Endocrine System 87 | 18,159
Female tissues 87 | 17,400
Skin and soft tissues 87 | 17,230
Male tissues 86 | 17,142
Blood and immune system 84 | 16,909
Respiratory system 84 | 16,393
Urinary Tract 84 | 16,678
Liver and Pancreas 83 | 16,750
Nervous System 83 | 16,725
Cardiovascular System 77 | 15,192

Target Family

Non-IDG 44 | 12,091
Enzyme 17 | 4,145
Ion Channel 14 | 344
Kinase 6 | 634
Transporter 5 | 473
GPCR 1 | 408

Compartment GO Term

Sarcoplasmic reticulum 87 | 87
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctophilin-3 JPH3 Tbio Non-IDG -1.51901 34.8 165
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Junctophilin-1 JPH1 Tbio Non-IDG -1.77250 56.2 92
CD2-associated protein CD2AP Tbio Non-IDG -3.44533 2735.9 82
Junctophilin-2 JPH2 Tbio Non-IDG -2.21890 163.0 229
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45