Development Level

Tbio 146 | 11,445
Tchem 18 | 1,598
Tclin 17 | 613
Tdark 12 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 21 | 979
abnormal embryo size 7 | 220
embryonic lethality prior to t... 6 | 278
abnormal behavior 4 | 298
decreased circulating glucose ... 4 | 126
decreased vertical activity 4 | 208
hyperactivity 4 | 148
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
decreased blood urea nitrogen ... 3 | 51
decreased body weight 3 | 161
decreased circulating choleste... 3 | 93
edema 3 | 59
embryonic lethality prior to o... 3 | 239
hemorrhage 3 | 23
increased heart weight 3 | 62
increased startle reflex 3 | 112
abnormal behavioral response t... 2 | 66
abnormal seminal vesicle morph... 2 | 114
abnormal tail morphology 2 | 25
cyanosis 2 | 7
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating total pr... 2 | 49
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased neutrophil cell numb... 2 | 42
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
increased circulating triglyce... 2 | 42
respiratory system phenotype 2 | 2
tremors 2 | 39
abnormal digit morphology 1 | 10
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal placenta vasculature 1 | 2
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal urinary bladder morph... 1 | 11
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased lactate dehydrogenas... 1 | 16
decreased mature B cell number 1 | 7
decreased red blood cell distr... 1 | 41
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased heart rate 1 | 23
increased mean corpuscular vol... 1 | 92
increased spleen weight 1 | 10
increased vertical activity 1 | 24
long tibia 1 | 25
male infertility 1 | 123
prenatal lethality 1 | 28
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened ST segment 1 | 10
small superior vagus ganglion 1 | 74
syndactyly 1 | 23
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 132 | 11,493
psoriasis 92 | 6,694
ovarian cancer 83 | 8,520
glioblastoma 75 | 5,792
medulloblastoma, large-cell 72 | 6,241
atypical teratoid / rhabdoid tumor 68 | 5,112
lung cancer 67 | 4,740
osteosarcoma 62 | 7,950
Breast cancer 57 | 3,578
adult high grade glioma 53 | 3,801
ependymoma 53 | 4,679
lung adenocarcinoma 52 | 2,716
Kidney cancer 49 | 2,613
malignant mesothelioma 48 | 3,232
group 3 medulloblastoma 47 | 4,104
pancreatic cancer 47 | 2,398
acute quadriplegic myopathy 45 | 1,158
primitive neuroectodermal tumor 45 | 3,035
invasive ductal carcinoma 44 | 2,951
Myopathy 43 | 185
lung carcinoma 43 | 2,843
non-small cell lung cancer 42 | 2,890
Cancer 41 | 2,499
Astrocytoma, Pilocytic 40 | 3,081
Autosomal recessive predisposition 40 | 1,442
Heart disease 40 | 306
colon cancer 40 | 1,478
diabetes mellitus 40 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,955
Cardiomyopathy 34 | 116
oligodendroglioma 34 | 2,850
astrocytic glioma 31 | 2,597
subependymal giant cell astrocytoma 31 | 2,287
Cardiomyopathy, Dilated 28 | 83
Dilated cardiomyopathy 28 | 56
Liver cancer 28 | 604
cystic fibrosis 28 | 1,696
breast carcinoma 27 | 1,638
Hypertrophic Cardiomyopathy 26 | 117
ductal carcinoma in situ 26 | 1,745
pituitary cancer 25 | 1,972
tuberculosis 25 | 2,010
Cerebrovascular disease 24 | 238
Coronary artery disease 24 | 268
Melanoma 24 | 711
group 4 medulloblastoma 24 | 1,855
Familial isolated dilated cardiomyopathy 23 | 41
LEFT VENTRICULAR NONCOMPACTION 10 23 | 40
LEFT VENTRICULAR NONCOMPACTION 8 23 | 40
Hypertension 22 | 396
Pick disease 22 | 1,894
Schizophrenia 22 | 1,160
ulcerative colitis 22 | 1,819
Duchenne muscular dystrophy 21 | 601
Skin cancer 21 | 469
Epilepsy 20 | 792
Heart failure 20 | 162
primary pancreatic ductal adenocarcinoma 19 | 1,109
Atrial Fibrillation 18 | 124
Myocardial Infarction 18 | 151
dermatomyositis 18 | 966
Alzheimer's disease 17 | 658
Kidney disease 17 | 430
Rheumatoid arthritis 17 | 1,191
adrenocortical carcinoma 17 | 1,428
juvenile dermatomyositis 17 | 1,187
spina bifida 17 | 1,074
Acquired scoliosis 16 | 281
Congestive heart failure 16 | 113
Curvature of spine 16 | 282
Endometrial cancer 16 | 311
astrocytoma 16 | 1,146
nasopharyngeal carcinoma 16 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Amyotrophic lateral sclerosis 15 | 451
Cardiac Arrhythmia 15 | 103
Creatine phosphokinase serum increased 15 | 110
Distal arthrogryposis 15 | 42
Elevated creatine kinase 15 | 110
Liver Cirrhosis, Experimental 15 | 769
active ulcerative colitis 15 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510
Amyloidosis 14 | 67
Bipolar Disorder 14 | 666
Byzanthine arch palate 14 | 194
Nemaline myopathy 14 | 17
Seizures 14 | 596
Short stature 14 | 531
Cardiomyopathies 13 | 110
Muscle hypotonia 13 | 571
Proximal muscle weakness 13 | 47
Proximal neurogenic muscle weakness 13 | 47
Respiratory Insufficiency 13 | 132
interstitial cystitis 13 | 2,312
Asthma 12 | 385
Atherosclerosis 12 | 291
Hypoplastic mandible condyle 12 | 275
Mandibular hypoplasia 12 | 275

Tissue

Endocrine System 192 | 18,159
Digestive Tract 190 | 17,369
Female tissues 187 | 17,400
Male tissues 187 | 17,142
Skin and soft tissues 187 | 17,230
Blood and immune system 185 | 16,909
Urinary Tract 183 | 16,678
Liver and Pancreas 180 | 16,750
Cardiovascular System 178 | 15,192
Nervous System 176 | 16,725
Respiratory system 170 | 16,393

Target Family

Non-IDG 137 | 12,091
Enzyme 26 | 4,145
Ion Channel 11 | 344
Kinase 7 | 634
Transcription Factor 7 | 1,400
Transporter 4 | 473
Epigenetic 1 | 242

Compartment GO Term

Sarcomere 193 | 193
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
Myosin light chain 1/3, skeletal muscle isoform MYL1 Tbio Non-IDG -2.11698 129.3 109
CD2-associated protein CD2AP Tbio Non-IDG -3.44533 2735.9 82
Leiomodin-3 LMOD3 Tbio Non-IDG -1.00928 10.3 27
Desmin DES Tbio Non-IDG -1.56068 36.6 991