Development Level

Tbio 61 | 10,625
Tclin 18 | 602
Tchem 15 | 1,890
Tdark 2 | 7,003

Collection

Eligible Ion Channel Proteins 4 | 117

IMPC Term

preweaning lethality, complete... 4 | 633
abnormal behavior 3 | 226
impaired glucose tolerance 3 | 52
increased or absent threshold ... 3 | 128
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
decreased grip strength 2 | 123
embryonic lethality prior to t... 2 | 187
improved glucose tolerance 2 | 56
increased circulating sodium l... 2 | 71
increased grip strength 2 | 83
increased startle reflex 2 | 38
abnormal coat/hair pigmentatio... 1 | 54
abnormal ear morphology 1 | 5
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal eye size 1 | 11
abnormal facial morphology 1 | 9
abnormal gait 1 | 51
abnormal heart left ventricle ... 1 | 20
abnormal iris pigmentation 1 | 3
abnormal lens morphology 1 | 73
abnormal placenta vasculature 1 | 2
abnormal skin morphology 1 | 23
abnormal vibrissa morphology 1 | 17
absent startle reflex 1 | 15
cyanosis 1 | 6
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating magnesiu... 1 | 11
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
edema 1 | 11
enlarged epididymis 1 | 27
hemorrhage 1 | 12
hyperactivity 1 | 108
hypoactivity 1 | 89
increased B cell number 1 | 23
increased NK T cell number 1 | 11
increased T cell number 1 | 15
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating total pr... 1 | 20
increased eosinophil cell numb... 1 | 9
increased gamma-delta T cell n... 1 | 16
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
limb grasping 1 | 35
polycystic kidney 1 | 9
prenatal lethality 1 | 16
preweaning lethality, incomple... 1 | 260
respiratory system phenotype 1 | 2
small superior vagus ganglion 1 | 20

Disease

ovarian cancer 49 | 8,484
osteosarcoma 48 | 7,933
psoriasis 48 | 6,685
glioblastoma 44 | 5,572
medulloblastoma, large-cell 43 | 6,234
atypical teratoid / rhabdoid tumor 37 | 4,369
lung cancer 36 | 4,466
primitive neuroectodermal tumor 34 | 3,031
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,289
invasive ductal carcinoma 31 | 2,950
Carcinoma 30 | 2,147
colon cancer 29 | 1,475
Breast cancer 28 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,988
lung carcinoma 28 | 2,844
oligodendroglioma 28 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
pilocytic astrocytoma 25 | 3,086
Myopathy 23 | 128
lung adenocarcinoma 23 | 2,713
pediatric high grade glioma 23 | 2,712
ependymoma 22 | 2,514
pancreatic cancer 22 | 2,300
pituitary cancer 22 | 1,972
ductal carcinoma in situ 21 | 1,745
adult high grade glioma 20 | 2,148
astrocytic glioma 20 | 2,241
group 4 medulloblastoma 20 | 1,875
non-small cell lung cancer 20 | 2,798
subependymal giant cell astrocytoma 20 | 2,287
Cancer 19 | 2,346
malignant mesothelioma 19 | 3,162
Cardiomyopathy 17 | 110
breast carcinoma 16 | 1,614
diabetes mellitus 16 | 1,663
primary pancreatic ductal adenocarcinoma 16 | 1,271
ulcerative colitis 16 | 2,087
Heart disease 15 | 279
Pick disease 15 | 1,893
limb-girdle muscular dystrophy 15 | 36
posterior fossa group A ependymoma 15 | 1,511
acute quadriplegic myopathy 14 | 1,157
astrocytoma 14 | 1,493
dermatomyositis 14 | 933
Duchenne muscular dystrophy 13 | 602
adrenocortical carcinoma 13 | 1,427
group 3 medulloblastoma 13 | 2,254
interstitial cystitis 13 | 2,299
Epilepsy 12 | 346
Hypertension 12 | 287
cystic fibrosis 12 | 1,665
medulloblastoma 12 | 1,524
tuberculosis 12 | 1,557
Malignant hyperthermia 11 | 25
Muscular dystrophy 11 | 48
cutaneous lupus erythematosus 11 | 1,056
posterior fossa group B ependymoma 11 | 1,530
Long QT syndrome 10 | 52
Obesity 10 | 616
Rheumatoid Arthritis 10 | 1,160
Schizophrenia 10 | 501
nasopharyngeal carcinoma 10 | 1,056
Brugada syndrome 9 | 26
Cardiomyopathies 9 | 90
Neuropathy 9 | 210
sonic hedgehog group medulloblastoma 9 | 1,482
Atopic dermatitis 8 | 944
Atrial Fibrillation 8 | 110
Brugada Syndrome (disorder) 8 | 15
Hypertensive disease 8 | 193
Status Epilepticus 8 | 85
aldosterone-producing adenoma 8 | 664
atypical teratoid/rhabdoid tumor 8 | 1,095
fibroadenoma 8 | 557
hereditary spastic paraplegia 8 | 313
Bipolar Disorder 7 | 266
Cerebrovascular disease 7 | 231
Down syndrome 7 | 548
Hypoglycemia 7 | 81
Kidney cancer 7 | 118
Kidney disease 7 | 396
Neurodegenerative disease 7 | 383
pancreatic carcinoma 7 | 567
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
Alzheimer's disease 6 | 644
Amyotrophic Lateral Sclerosis 6 | 431
Hyperglycemia 6 | 120
Hyperinsulinism 6 | 63
Hypokalemia 6 | 40
Hypokalemic periodic paralysis 6 | 13
Intellectual disability 6 | 573
Multiple myeloma 6 | 1,327
Myocardial Ischemia 6 | 169
Seizures 6 | 95
Sudden infant death syndrome 6 | 33
Vascular disease 6 | 281
esophageal adenocarcinoma 6 | 737
gastric carcinoma 6 | 832
juvenile dermatomyositis 6 | 1,189
spina bifida 6 | 1,064

Tissue

Blood and immune system 96 | 17,995
Cardiovascular System 96 | 17,958
Digestive Tract 96 | 18,473
Endocrine System 96 | 18,512
Female tissues 96 | 18,647
Liver and Pancreas 96 | 18,136
Male tissues 96 | 17,969
Nervous System 96 | 18,561
Skin and soft tissues 96 | 18,115
Urinary Tract 96 | 18,444
Respiratory system 95 | 17,484

Target Family

Non-IDG 54 | 11,971
Ion Channel 19 | 341
Transporter 13 | 473
Enzyme 10 | 4,146

Compartment GO Term

Sarcolemma 96 | 96
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474
Laminin subunit alpha-2 LAMA2 Tbio Non-IDG -2.48634 321.9 131
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Neuroblast differentiation-associated protein AHNAK AHNAK Tbio Non-IDG -1.61845 51.3 82
Beta-1-syntrophin SNTB1 Tbio Non-IDG -1.02258 8.71 102
Blood vessel epicardial substance BVES Tbio Non-IDG -1.46376 36.1 156
Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 Tchem Ion Channel -1.43080 25.0 426
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A PDE9A Tchem Enzyme -1.87754 73.1 142
Protein AHNAK2 AHNAK2 Tdark Non-IDG -0.55630 3.31 58
Sarcolemmal membrane-associated protein SLMAP Tbio Non-IDG -1.27251 18.4 57