Development Level

Tbio 67 | 10,625
Tchem 13 | 1,890
Tdark 8 | 7,003
Tclin 2 | 602

Collection

Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

preweaning lethality, complete... 8 | 633
embryonic lethality prior to o... 5 | 148
abnormal behavior 4 | 226
abnormal embryo size 4 | 112
decreased body weight 4 | 174
decreased lean body mass 3 | 195
hypoactivity 3 | 89
abnormal eye morphology 2 | 38
abnormal hindbrain development 2 | 24
abnormal maxilla morphology 2 | 16
abnormal neural tube closure 2 | 37
abnormal tooth morphology 2 | 24
decreased body length 2 | 108
decreased caudal vertebrae num... 2 | 49
decreased circulating LDL chol... 2 | 37
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
increased circulating alkaline... 2 | 119
preweaning lethality, incomple... 2 | 260
abnormal QRS complex 1 | 25
abnormal bone mineralization 1 | 55
abnormal coat- hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal digit morphology 1 | 13
abnormal eye size 1 | 11
abnormal forebrain development 1 | 18
abnormal locomotor activation 1 | 26
abnormal midbrain development 1 | 22
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal seminal vesicle morph... 1 | 47
abnormal vocalization 1 | 21
anophthalmia 1 | 20
craniofacial phenotype 1 | 9
decreased Ly6C low monocyte nu... 1 | 23
decreased NK T cell number 1 | 28
decreased circulating HDL chol... 1 | 77
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating total pr... 1 | 41
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
increased blood urea nitrogen ... 1 | 44
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating creatini... 1 | 29
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased plasma cell number 1 | 5
increased sacral vertebrae num... 1 | 62
male infertility 1 | 62
microphthalmia 1 | 15
pale yolk sac 1 | 12
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34
trunk curl 1 | 15

Disease

ovarian cancer 57 | 8,491
osteosarcoma 52 | 7,933
Cancer 35 | 2,346
medulloblastoma, large-cell 35 | 6,234
lung cancer 34 | 4,473
glioblastoma 33 | 5,572
psoriasis 32 | 6,685
atypical teratoid / rhabdoid tumor 28 | 4,369
primitive neuroectodermal tumor 27 | 3,031
group 3 medulloblastoma 22 | 2,254
Carcinoma 21 | 2,147
ependymoma 20 | 2,514
oligodendroglioma 20 | 2,849
Breast cancer 19 | 3,098
malignant mesothelioma 19 | 3,163
Rheumatoid Arthritis 18 | 1,170
lung adenocarcinoma 18 | 2,714
pediatric high grade glioma 18 | 2,712
Intellectual disability 16 | 573
Multiple myeloma 15 | 1,327
astrocytoma 15 | 1,493
pilocytic astrocytoma 14 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
invasive ductal carcinoma 13 | 2,950
medulloblastoma 13 | 1,524
Waldenstrons macroglobulinemia 12 | 764
acute myeloid leukemia 12 | 785
astrocytic glioma 12 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
sonic hedgehog group medulloblastoma 12 | 1,482
Pick disease 11 | 1,893
diabetes mellitus 11 | 1,663
Endometriosis 10 | 535
adrenocortical carcinoma 10 | 1,427
adult high grade glioma 10 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
non-small cell lung cancer 10 | 2,798
spina bifida 10 | 1,064
subependymal giant cell astrocytoma 10 | 2,287
colon cancer 9 | 1,475
dermatomyositis 9 | 966
group 4 medulloblastoma 9 | 1,875
Coffin-Siris syndrome 8 | 17
ductal carcinoma in situ 8 | 1,745
juvenile dermatomyositis 8 | 1,189
lung carcinoma 8 | 2,844
pituitary cancer 8 | 1,972
Adenoid Cystic Carcinoma 7 | 99
acute quadriplegic myopathy 7 | 1,157
posterior fossa group A ependymoma 7 | 1,511
Bladder Neoplasm 6 | 109
Liver carcinoma 6 | 217
Sezary Syndrome 6 | 26
progressive supranuclear palsy 6 | 674
Kidney cancer 5 | 121
Melanoma 5 | 261
Neuroblastoma 5 | 78
Pancreatic Neoplasm 5 | 79
Schimke immuno-osseous dysplasia 5 | 9
Schizophrenia 5 | 503
aldosterone-producing adenoma 5 | 664
cystic fibrosis 5 | 1,670
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
ulcerative colitis 5 | 2,087
Adenocarcinoma 4 | 115
Borjeson-Forssman-Lehmann syndrome 4 | 6
Cleft palate 4 | 125
Cockayne syndrome 4 | 54
Endometrial Neoplasms 4 | 50
Small cell carcinoma of lung 4 | 45
Squamous cell carcinoma 4 | 96
Williams-Beuren syndrome 4 | 45
breast carcinoma 4 | 1,614
nasopharyngeal carcinoma 4 | 1,056
non-small cell lung carcinoma 4 | 413
pancreatic cancer 4 | 2,300
posterior fossa group B ependymoma 4 | 1,530
primary pancreatic ductal adenocarcinoma 4 | 1,271
tuberculosis 4 | 1,563
Adenoma 3 | 165
Alzheimer's disease 3 | 644
Amyotrophic Lateral Sclerosis 3 | 432
Carcinoma, Transitional Cell 3 | 31
Colorectal Neoplasms 3 | 217
IGA Glomerulonephritis 3 | 454
Leishmaniasis 3 | 49
Liver cancer 3 | 31
Lung Neoplasms 3 | 171
Mammary Neoplasms 3 | 410
Neurodegenerative disease 3 | 383
Prostatic Neoplasms 3 | 471
Squamous cell carcinoma of esophagus 3 | 82
Stomach Neoplasms 3 | 282
Urinary bladder cancer 3 | 34
atypical teratoid/rhabdoid tumor 3 | 1,095
gastric carcinoma 3 | 832
glioblastoma multiforme 3 | 347
hepatocellular carcinoma 3 | 550
hereditary spastic paraplegia 3 | 313
tuberculosis and treatment for 6 months 3 | 686

Tissue

Blood and immune system 90 | 17,994
Cardiovascular System 90 | 17,957
Digestive Tract 90 | 18,472
Endocrine System 90 | 18,511
Female tissues 90 | 18,646
Liver and Pancreas 90 | 18,135
Male tissues 90 | 17,968
Nervous System 90 | 18,560
Respiratory system 90 | 17,483
Skin and soft tissues 90 | 18,114
Urinary Tract 90 | 18,443

Target Family

Non-IDG 42 | 11,969
Epigenetic 24 | 242
Transcription Factor 14 | 1,400
Enzyme 4 | 4,146
TF/Epigenetic 4 | 38
Kinase 2 | 634

Compartment GO Term

SWI/SNF superfamily-type compl... 90 | 90
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.09050 11730.8 2241
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 SMARCAL1 Tbio Non-IDG -1.71575 60.2 110
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.16064 142.8 42
Zinc finger protein ZFPM1 ZFPM1 Tbio Transcription Factor -2.50335 310.9 77
Transcriptional repressor p66-alpha GATAD2A Tbio Non-IDG -0.83060 7.11 142
Actin-like protein 6B ACTL6B Tbio Non-IDG -0.79164 6.22 112
Histone-binding protein RBBP4 RBBP4 Tbio Non-IDG -1.68453 51.8 276
Remodeling and spacing factor 1 RSF1 Tbio Epigenetic -1.65153 49.2 57
Zinc finger HIT domain-containing protein 1 ZNHIT1 Tdark Non-IDG -0.29003 1.92 92
Death domain-associated protein 6 DAXX Tbio Non-IDG -2.30299 222.3 672