Development Level

Tbio 72 | 11,651
Tchem 11 | 1,388
Tdark 6 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 19 | 979
abnormal embryo size 6 | 220
embryonic lethality prior to o... 6 | 239
decreased body weight 5 | 161
embryonic lethality prior to t... 4 | 278
abnormal behavior 3 | 298
hypoactivity 3 | 132
increased circulating alkaline... 3 | 122
abnormal craniofacial morpholo... 2 | 33
abnormal eye morphology 2 | 68
abnormal maxilla morphology 2 | 17
abnormal seminal vesicle morph... 2 | 114
abnormal tooth morphology 2 | 24
decreased circulating LDL chol... 2 | 38
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
edema 2 | 59
increased circulating HDL chol... 2 | 80
increased hemoglobin content 2 | 45
increased mean platelet volume 2 | 45
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal stomach morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal vocalization 1 | 21
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased NK T cell number 1 | 2
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased erythrocyte cell num... 1 | 62
decreased fluid intake 1 | 3
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lumbar vertebrae num... 1 | 2
decreased red blood cell distr... 1 | 41
decreased sacral vertebrae num... 1 | 1
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased body temperature 1 | 9
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased lumbar vertebrae num... 1 | 1
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased sacral vertebrae num... 1 | 1
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
thrombocytopenia 1 | 56
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 68 | 11,493
ovarian cancer 59 | 8,520
osteosarcoma 52 | 7,950
group 3 medulloblastoma 41 | 4,104
Cancer 40 | 2,499
lung cancer 37 | 4,740
glioblastoma 35 | 5,792
medulloblastoma, large-cell 35 | 6,241
psoriasis 32 | 6,694
atypical teratoid / rhabdoid tumor 30 | 5,112
ependymoma 30 | 4,679
Breast cancer 27 | 3,578
primitive neuroectodermal tumor 27 | 3,035
Kidney cancer 25 | 2,613
malignant mesothelioma 20 | 3,232
oligodendroglioma 20 | 2,850
Intellectual disability 18 | 1,016
Rheumatoid arthritis 18 | 1,191
adult high grade glioma 18 | 3,801
lung adenocarcinoma 18 | 2,716
Multiple myeloma 16 | 1,332
astrocytic glioma 16 | 2,597
Astrocytoma, Pilocytic 15 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
invasive ductal carcinoma 13 | 2,951
Waldenstrons macroglobulinemia 12 | 765
acute myeloid leukemia 12 | 783
astrocytoma 12 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
pediatric high grade glioma 12 | 1,064
Pick disease 11 | 1,894
dermatomyositis 11 | 966
diabetes mellitus 11 | 1,728
subependymal giant cell astrocytoma 11 | 2,287
Coffin-Siris syndrome 10 | 17
Endometriosis 10 | 540
Liver cancer 10 | 604
Short stature 10 | 531
adrenocortical carcinoma 10 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
non-small cell lung cancer 10 | 2,890
Broad flat nasal bridge 9 | 236
Dull intelligence 9 | 645
Epilepsy 9 | 792
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Nasal bridge wide 9 | 236
Poor school performance 9 | 645
Schizophrenia 9 | 1,160
Seizures 9 | 596
Small head 9 | 374
colon cancer 9 | 1,478
group 4 medulloblastoma 9 | 1,855
lung carcinoma 9 | 2,843
spina bifida 9 | 1,074
Fetal Growth Retardation 8 | 189
Infant, Small for Gestational Age 8 | 176
Intrauterine retardation 8 | 176
Macrostomia 8 | 72
Muscle hypotonia 8 | 571
ductal carcinoma in situ 8 | 1,745
juvenile dermatomyositis 8 | 1,187
pituitary cancer 8 | 1,972
Adenoid Cystic Carcinoma 7 | 99
Carcinoma, Adenoid Cystic 7 | 99
Cognitive delay 7 | 608
Cryptorchidism 7 | 296
Endometrial cancer 7 | 311
Full lower lip 7 | 64
Global developmental delay 7 | 608
Immune system cancer 7 | 140
Melanoma 7 | 711
Mental and motor retardation 7 | 608
Prominent lower lip 7 | 64
acute quadriplegic myopathy 7 | 1,158
pancreatic cancer 7 | 2,398
Acquired scoliosis 6 | 281
Bladder Neoplasm 6 | 112
Carcinoma, Hepatocellular 6 | 228
Coarse facial features 6 | 108
Concave bridge of nose 6 | 195
Curvature of spine 6 | 282
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Feeding difficulties in infancy 6 | 175
Liver carcinoma 6 | 240
Long eyelashes 6 | 37
Lymphoid leukemia 6 | 160
Sezary Syndrome 6 | 27
Strabismus 6 | 270
Thickened facial skin with coarse facial features 6 | 108
Urinary Bladder Neoplasms 6 | 114
medulloblastoma 6 | 720
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
progressive supranuclear palsy 6 | 676
ulcerative colitis 6 | 1,819
Depressed nasal ridge 5 | 51
Hypoplastic mandible condyle 5 | 275
aldosterone-producing adenoma 5 | 665

Tissue

Skin and soft tissues 91 | 17,230
Blood and immune system 90 | 16,909
Cardiovascular System 90 | 15,192
Digestive Tract 90 | 17,369
Endocrine System 90 | 18,159
Liver and Pancreas 90 | 16,750
Nervous System 90 | 16,725
Female tissues 89 | 17,400
Male tissues 89 | 17,142
Respiratory system 89 | 16,393
Urinary Tract 88 | 16,678

Target Family

Non-IDG 42 | 12,091
Epigenetic 25 | 242
Transcription Factor 16 | 1,400
Enzyme 4 | 4,145
TF/Epigenetic 4 | 38

Compartment GO Term

SWI/SNF superfamily-type compl... 91 | 91
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
INO80 complex subunit B INO80B Tbio Non-IDG -1.16370 15.1 53
E1A-binding protein p400 EP400 Tbio Non-IDG -1.47248 27.6 69
Transcriptional repressor p66-beta GATAD2B Tbio Transcription Factor -1.00210 9.37 215
DNA helicase INO80 INO80 Tbio Enzyme -2.54124 327.2 47
REST corepressor 1 RCOR1 Tbio Transcription Factor -1.96775 81.2 0
Ubiquitin carboxyl-terminal hydrolase isozyme L5 UCHL5 Tbio Enzyme -1.71687 51.9 225
Zinc finger HIT domain-containing protein 1 ZNHIT1 Tdark Non-IDG -0.41378 2.04 99
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.80737 619.7 475
Transcriptional repressor p66-alpha GATAD2A Tbio Non-IDG -0.85553 8.21 159
Zinc finger protein ZFPM1 ZFPM1 Tbio Transcription Factor -2.52665 326.6 82