Development Level

Tbio 5 | 11,445

Disease

Cancer 4 | 2,499
ovarian cancer 4 | 8,520
Carcinoma 3 | 11,493
Craniofacial Abnormalities 3 | 151
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Pulmonary Fibrosis 3 | 106
Ureteral obstruction 3 | 33
group 3 medulloblastoma 3 | 4,104
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
subependymal giant cell astrocytoma 3 | 2,287
Breast cancer 2 | 3,578
Chronic fatigue syndrome 2 | 25
Colorectal Neoplasms 2 | 243
Congenital Camptodactyly 2 | 40
Hypertensive disease 2 | 292
Increase in blood pressure 2 | 119
Inflammatory bowel disease 2 | 151
Liver Cirrhosis, Experimental 2 | 769
Liver disease 2 | 237
Loeys-Dietz syndrome 2 | 23
Multiple myeloma 2 | 1,332
Orbital separation excessive 2 | 244
Osteoarthritis 2 | 184
Peyronie's disease 2 | 9
Pneumonia 2 | 174
Systemic scleroderma 2 | 60
Ventricular Remodeling 2 | 5
Waldenstrons macroglobulinemia 2 | 765
atypical teratoid / rhabdoid tumor 2 | 5,112
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
tuberculosis 2 | 2,010
Abnormality of the iris 1 | 14
Acquired flat foot 1 | 72
Adenocarcinoma Of Esophagus 1 | 14
Aneurysm, Dissecting 1 | 8
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Aortic aneurysm 1 | 38
Aortic aneurysm, familial thoracic 3 1 | 13
Aortic valve stenosis 1 | 28
Arterial tortuosity 1 | 5
Ascending aortic dissection 1 | 13
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Biliary tract cancer 1 | 19
Bushy eyebrows 1 | 49
Carcinoma of pancreas 1 | 5
Carcinoma, Ductal, Breast 1 | 11
Cone-shaped epiphyses 1 | 24
Convex nasal bridge 1 | 57
Copper-Overload Cirrhosis 1 | 11
Cutis marmorata 1 | 32
Cystic medial necrosis of aorta 1 | 13
Descending aortic dissection 1 | 13
Diffusely thickened skin 1 | 20
Dissection of aorta 1 | 9
Dyspnea on exertion 1 | 24
Dyspnea, Paroxysmal 1 | 13
Familial thoracic aortic aneurysm and aortic dissection 1 | 13
Fibroid Tumor 1 | 6
Flatfoot 1 | 73
Fused vertebrae 1 | 25
Gastrointestinal hamartomatous polyps 1 | 10
Gastrointestinal system disease 1 | 54
Hamartomatous polyp 1 | 10
Hepatitis, Chronic 1 | 23
Hypokalemia 1 | 52
Hypoplastic finger 1 | 17
Impaired left ventricular function 1 | 16
Increased risk of pancreatic cancer 1 | 9
Invasive Ductal Breast Carcinoma 1 | 9
Joint laxity 1 | 54
Left-Sided Heart Failure 1 | 16
Leiomyoma 1 | 32
Linear atrophy 1 | 15
Liver Diseases, Parasitic 1 | 9
Loeys-Dietz Aortic Aneurysm Syndrome 1 | 13
Malignant neoplasm of pancreas 1 | 9
Malocclusion 1 | 57
Mitral Valve Prolapse Syndrome 1 | 39
Mitral regurgitation, mild 1 | 32
Osteochondritis dissecans 1 | 17
Pachyderma 1 | 20
Pericardial effusion 1 | 14
Peutz-Jeghers syndrome 1 | 21
Platyspondyly 1 | 56
Short finger 1 | 17
Short tubular bones 1 | 22
Simple syndactyly of toes, first web space 1 | 23
Spinal fusion 1 | 25
Sternal anomalies 1 | 19
Stomach cancer 1 | 30
Thyroid cancer 1 | 36
Vertebral body fusion 1 | 25

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Transcription Factor 4 | 1,400
Non-IDG 1 | 12,091

Compartment GO Term

SMAD2 protein complex 5 | 5
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sterile alpha and TIR motif-containing protein 1 SARM1 Tbio Non-IDG -2.22753 163.9 159
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Mothers against decapentaplegic homolog 3 SMAD3 Tbio Transcription Factor -3.19667 1403.6 1526
Mothers against decapentaplegic homolog 7 SMAD7 Tbio Transcription Factor -2.81953 638.7 387
Mothers against decapentaplegic homolog 2 SMAD2 Tbio Transcription Factor -3.26675 1515.7 1396