Development Level

Tbio 66 | 11,445
Tchem 12 | 1,598
Tdark 6 | 6,588
Tclin 5 | 613

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased body weight 5 | 161
preweaning lethality, complete... 4 | 979
decreased circulating triglyce... 3 | 79
increased circulating alkaline... 3 | 122
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
cardiovascular system phenotyp... 2 | 36
decreased circulating LDL chol... 2 | 38
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased leukocyte cell numbe... 2 | 73
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased vertical activity 2 | 24
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coping response 1 | 1
abnormal cranium morphology 1 | 36
abnormal digestive system phys... 1 | 1
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 4
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
absent vibrissae 1 | 12
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
enlarged spleen 1 | 41
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased mature B cell number 1 | 1
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
small thymus 1 | 16
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 70 | 11,493
ovarian cancer 57 | 8,520
osteosarcoma 56 | 7,950
glioblastoma 44 | 5,792
medulloblastoma, large-cell 40 | 6,241
psoriasis 39 | 6,694
Cancer 33 | 2,499
atypical teratoid / rhabdoid tumor 32 | 5,112
lung cancer 32 | 4,740
Breast cancer 31 | 3,578
malignant mesothelioma 30 | 3,232
ependymoma 29 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
interstitial cystitis 26 | 2,312
group 3 medulloblastoma 25 | 4,104
pancreatic cancer 25 | 2,398
Astrocytoma, Pilocytic 24 | 3,081
lung adenocarcinoma 24 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
invasive ductal carcinoma 22 | 2,951
adult high grade glioma 21 | 3,801
lung carcinoma 21 | 2,843
non-small cell lung cancer 21 | 2,890
breast carcinoma 20 | 1,638
subependymal giant cell astrocytoma 20 | 2,287
Kidney cancer 18 | 2,613
oligodendroglioma 18 | 2,850
diabetes mellitus 17 | 1,728
adrenocortical carcinoma 16 | 1,428
astrocytic glioma 16 | 2,597
tuberculosis 16 | 2,010
primitive neuroectodermal tumor 15 | 3,035
ulcerative colitis 14 | 1,819
colon cancer 13 | 1,478
spina bifida 13 | 1,074
acute quadriplegic myopathy 12 | 1,158
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
pituitary cancer 12 | 1,972
primary pancreatic ductal adenocarcinoma 12 | 1,109
Pick disease 11 | 1,894
cutaneous lupus erythematosus 11 | 1,057
cystic fibrosis 11 | 1,696
Liver Cirrhosis, Experimental 10 | 769
group 4 medulloblastoma 10 | 1,855
juvenile dermatomyositis 10 | 1,187
Autosomal recessive predisposition 9 | 1,442
Schizophrenia 9 | 1,160
astrocytoma 9 | 1,146
ductal carcinoma in situ 9 | 1,745
pediatric high grade glioma 9 | 1,064
Neoplasm Invasiveness 8 | 161
pancreatic carcinoma 8 | 562
Alzheimer's disease 7 | 658
Bipolar Disorder 7 | 666
Breast Neoplasms 7 | 445
Mammary Neoplasms 7 | 425
Melanoma 7 | 711
Multiple Sclerosis 7 | 540
Waldenstrons macroglobulinemia 7 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
gastric carcinoma 7 | 807
hepatocellular carcinoma 7 | 547
nasopharyngeal carcinoma 7 | 1,058
primary Sjogren syndrome 7 | 735
sonic hedgehog group medulloblastoma 7 | 467
Atopic dermatitis 6 | 952
Colorectal Neoplasms 6 | 243
Down syndrome 6 | 499
Duchenne muscular dystrophy 6 | 601
Intellectual disability 6 | 1,016
Mental Depression 6 | 333
Multiple myeloma 6 | 1,332
Neoplasm Metastasis 6 | 168
Osteoporosis 6 | 363
Prostatic Neoplasms 6 | 495
Renal Cell Carcinoma 6 | 214
Rheumatoid arthritis 6 | 1,191
Stomach Neoplasms 6 | 300
aldosterone-producing adenoma 6 | 665
dermatomyositis 6 | 966
fibroadenoma 6 | 559
gastric cancer 6 | 459
mucosa-associated lymphoid tissue lymphoma 6 | 484
Aarskog syndrome 5 | 12
Amyotrophic lateral sclerosis 5 | 451
Asthma 5 | 385
Carcinoma of colon 5 | 32
Carcinoma, Hepatocellular 5 | 228
Crohn's disease 5 | 321
Kidney disease 5 | 430
Liver carcinoma 5 | 240
Nonsyndromic deafness 5 | 142
Parkinson's disease 5 | 392
Skin cancer 5 | 469
atypical teratoid/rhabdoid tumor 5 | 357
medulloblastoma 5 | 720
progressive supranuclear palsy 5 | 676
Vascular disease 4 | 319
esophageal adenocarcinoma 4 | 737

Tissue

Blood and immune system 87 | 16,909
Endocrine System 87 | 18,159
Liver and Pancreas 87 | 16,750
Male tissues 87 | 17,142
Skin and soft tissues 87 | 17,230
Urinary Tract 87 | 16,678
Digestive Tract 86 | 17,369
Female tissues 86 | 17,400
Respiratory system 86 | 16,393
Cardiovascular System 85 | 15,192
Nervous System 85 | 16,725

Target Family

Non-IDG 55 | 12,091
Enzyme 20 | 4,145
Kinase 11 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

Compartment GO Term

Ruffle membrane 89 | 89
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A-kinase anchor protein 11 AKAP11 Tbio Enzyme -1.02415 11.7 38
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Prolyl endopeptidase FAP FAP Tchem Enzyme -2.37686 226.2 406
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
PH and SEC7 domain-containing protein 1 PSD Tbio Non-IDG -2.13025 139.8 20
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 MACF1 Tbio Non-IDG -2.05246 115.8 45
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Putative PIP5K1A and PSMD4-like protein PIPSL Tdark Non-IDG -0.63348 5.88 0
Cdc42 effector protein 1 CDC42EP1 Tbio Non-IDG -0.84557 7.77 106
C2 domain-containing protein 5 C2CD5 Tbio Non-IDG -0.04792 1.71 33