Development Level

Tbio 123 | 11,178
Tchem 19 | 1,885
Tdark 9 | 6,569
Tclin 7 | 612

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal bone structure 7 | 187
preweaning lethality, incomple... 6 | 499
decreased body weight 5 | 161
increased heart weight 5 | 62
increased startle reflex 5 | 112
abnormal behavior 4 | 298
abnormal embryo size 4 | 220
abnormal retina morphology 4 | 71
decreased circulating triglyce... 4 | 79
edema 4 | 59
abnormal coat-hair pigmentatio... 3 | 64
decreased bone mineral content 3 | 151
decreased caudal vertebrae num... 3 | 53
decreased circulating LDL chol... 3 | 38
decreased circulating alanine ... 3 | 47
decreased circulating choleste... 3 | 93
hyperactivity 3 | 148
increased circulating alkaline... 3 | 122
increased lean body mass 3 | 172
abnormal eye morphology 2 | 68
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
decreased circulating HDL chol... 2 | 68
decreased circulating serum al... 2 | 82
decreased mean corpuscular hem... 2 | 50
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
impaired pupillary reflex 2 | 26
increased circulating calcium ... 2 | 34
increased fasted circulating g... 2 | 76
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
persistence of hyaloid vascula... 2 | 33
short tibia 2 | 97
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal retinal inner nuclear... 1 | 8
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
absent vibrissae 1 | 12
anophthalmia 1 | 33
cataract 1 | 92
corneal opacity 1 | 32
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased prepulse inhibition 1 | 32
microphthalmia 1 | 26
small superior vagus ganglion 1 | 74
small testis 1 | 58
small thymus 1 | 16
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 121 | 11,192
ovarian cancer 98 | 8,297
osteosarcoma 93 | 7,766
glioblastoma 73 | 5,635
medulloblastoma, large-cell 71 | 6,086
psoriasis 70 | 6,514
Cancer 57 | 2,388
atypical teratoid / rhabdoid tumor 55 | 4,971
Breast cancer 54 | 3,469
lung cancer 54 | 4,607
ependymoma 52 | 4,559
pancreatic cancer 47 | 2,322
Astrocytoma, Pilocytic 46 | 3,006
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 44 | 3,204
malignant mesothelioma 43 | 3,135
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,902
Kidney cancer 41 | 2,548
adult high grade glioma 41 | 3,701
group 3 medulloblastoma 41 | 4,002
invasive ductal carcinoma 39 | 2,867
lung adenocarcinoma 38 | 2,627
interstitial cystitis 36 | 2,237
non-small cell lung cancer 34 | 2,799
subependymal giant cell astrocytoma 34 | 2,230
lung carcinoma 31 | 2,755
oligodendroglioma 31 | 2,768
astrocytic glioma 29 | 2,530
ulcerative colitis 29 | 1,765
colon cancer 27 | 1,428
tuberculosis 27 | 1,963
primitive neuroectodermal tumor 26 | 2,957
pituitary cancer 25 | 1,915
breast carcinoma 24 | 1,589
diabetes mellitus 23 | 1,683
adrenocortical carcinoma 22 | 1,385
cystic fibrosis 22 | 1,629
group 4 medulloblastoma 22 | 1,806
primary pancreatic ductal adenocarcinoma 22 | 1,071
Pick disease 21 | 1,856
ductal carcinoma in situ 21 | 1,686
spina bifida 21 | 1,053
acute quadriplegic myopathy 20 | 1,133
juvenile dermatomyositis 20 | 1,147
gastric carcinoma 18 | 781
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,911
Liver Cirrhosis, Experimental 17 | 733
cutaneous lupus erythematosus 17 | 1,016
astrocytoma 16 | 1,113
Autosomal recessive predisposition 14 | 1,407
Duchenne muscular dystrophy 14 | 587
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 492
pediatric high grade glioma 14 | 1,035
Atopic dermatitis 13 | 915
Intellectual disability 13 | 998
Kidney disease 13 | 411
Rheumatoid arthritis 13 | 1,156
Schizophrenia 13 | 1,136
aldosterone-producing adenoma 13 | 646
Alzheimer's disease 12 | 640
Bipolar Disorder 12 | 646
Neoplasm Invasiveness 12 | 151
Liver cancer 11 | 589
esophageal adenocarcinoma 11 | 696
mucosa-associated lymphoid tissue lymphoma 11 | 473
nasopharyngeal carcinoma 11 | 1,024
pancreatic carcinoma 11 | 555
primary Sjogren syndrome 11 | 710
sonic hedgehog group medulloblastoma 11 | 459
Down syndrome 10 | 480
dermatomyositis 10 | 941
Aarskog syndrome 9 | 12
Mental Depression 9 | 325
Multiple Sclerosis 9 | 527
Multiple myeloma 9 | 1,296
Obesity 9 | 655
Stomach Neoplasms 9 | 287
Waldenstrons macroglobulinemia 9 | 742
Breast Neoplasms 8 | 423
Melanoma 8 | 689
active Crohn's disease 8 | 882
hepatocellular carcinoma 8 | 536
medulloblastoma 8 | 702
progressive supranuclear palsy 8 | 656
sarcoidosis 8 | 357
Amyotrophic lateral sclerosis 7 | 437
Epilepsy 7 | 775
Mammary Neoplasms 7 | 403
Osteoporosis 7 | 348
Polycystic ovary syndrome 7 | 348
Prostatic Neoplasms 7 | 472
Seizures 7 | 584
atypical teratoid/rhabdoid tumor 7 | 349
gastric cancer 7 | 445
Adenoma 6 | 159
Asthma 6 | 370
Carcinoma, Hepatocellular 6 | 217
Depressive disorder 6 | 401
Liver carcinoma 6 | 229
fibroadenoma 6 | 538

Tissue

Blood and immune system 152 | 16,909
Endocrine System 152 | 18,159
Liver and Pancreas 152 | 16,750
Male tissues 152 | 17,142
Skin and soft tissues 152 | 17,230
Female tissues 151 | 17,400
Respiratory system 151 | 16,393
Urinary Tract 151 | 16,678
Digestive Tract 150 | 17,369
Nervous System 149 | 16,725
Cardiovascular System 148 | 15,192

Target Family

Non-IDG 110 | 12,091
Enzyme 28 | 4,145
Kinase 16 | 634
Transporter 2 | 473
GPCR 1 | 408
Ion Channel 1 | 344

Compartment GO Term

Ruffle 158 | 158
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctional protein associated with coronary artery disease JCAD Tbio Non-IDG -0.81180 6.70 18
Allograft inflammatory factor 1 AIF1 Tbio Non-IDG -3.07876 1105.3 601
ADP-ribosylation factor 4 ARF4 Tbio Enzyme -1.67012 46.6 163
Ras GTPase-activating-like protein IQGAP1 IQGAP1 Tbio Enzyme -2.27732 224.8 291
Pyridoxal phosphate phosphatase PDXP Tbio Enzyme -2.37320 235.7 79
Allograft inflammatory factor 1-like AIF1L Tdark Non-IDG -1.33601 20.8 16
Protein S100-A6 S100A6 Tbio Non-IDG -2.72619 530.5 328
Kelch-like protein 41 KLHL41 Tbio Non-IDG -1.26172 19.8 167
Rho guanine nucleotide exchange factor 4 ARHGEF4 Tbio Non-IDG -1.40554 28.0 126
Angiomotin AMOT Tchem Non-IDG -1.75932 64.8 318