Development Level

Tbio 115 | 10,625
Tchem 19 | 1,890
Tdark 9 | 7,003
Tclin 7 | 602

Collection

Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 145

IMPC Term

abnormal bone structure 6 | 131
preweaning lethality, incomple... 6 | 260
abnormal bone mineralization 5 | 55
preweaning lethality, complete... 5 | 633
decreased lean body mass 4 | 195
increased heart weight 4 | 37
abnormal behavior 3 | 226
decreased circulating LDL chol... 3 | 37
decreased circulating choleste... 3 | 85
decreased circulating triglyce... 3 | 83
decreased total body fat amoun... 3 | 186
abnormal coat/hair pigmentatio... 2 | 54
abnormal embryo size 2 | 112
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
cardiovascular system phenotyp... 2 | 35
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating insulin ... 2 | 75
decreased grip strength 2 | 123
increased circulating alkaline... 2 | 119
increased or absent threshold ... 2 | 128
abnormal QRS complex 1 | 25
abnormal cornea morphology 1 | 24
abnormal digit morphology 1 | 13
abnormal femur morphology 1 | 14
abnormal hindbrain development 1 | 24
abnormal liver morphology 1 | 5
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal respiratory quotient 1 | 9
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal vertebrae morphology 1 | 14
abnormal vibrissa morphology 1 | 17
absent vibrissae 1 | 14
corneal opacity 1 | 25
decreased IgE level 1 | 3
decreased IgG1 level 1 | 4
decreased Ly6C low monocyte nu... 1 | 23
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased effector memory CD8-... 1 | 24
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased threshold for audito... 1 | 32
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
fused cornea and lens 1 | 4
fused phalanges 1 | 1
hydrops fetalis 1 | 22
hyperactivity 1 | 108
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased Ly6C high monocyte n... 1 | 12
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased heart rate variabili... 1 | 4
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased mature B cell number 1 | 12
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22
shortened ST segment 1 | 9
small thymus 1 | 11
thrombocytosis 1 | 23

Disease

ovarian cancer 91 | 8,492
osteosarcoma 85 | 7,933
glioblastoma 68 | 5,572
medulloblastoma, large-cell 67 | 6,234
psoriasis 65 | 6,685
Cancer 54 | 2,346
pancreatic cancer 46 | 2,300
atypical teratoid / rhabdoid tumor 45 | 4,369
pilocytic astrocytoma 45 | 3,086
lung cancer 43 | 4,473
Breast cancer 42 | 3,099
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,988
invasive ductal carcinoma 38 | 2,950
malignant mesothelioma 37 | 3,163
lung adenocarcinoma 36 | 2,714
interstitial cystitis 34 | 2,299
Carcinoma 33 | 2,147
non-small cell lung cancer 32 | 2,798
pediatric high grade glioma 32 | 2,712
subependymal giant cell astrocytoma 31 | 2,287
lung carcinoma 30 | 2,844
ulcerative colitis 30 | 2,087
oligodendroglioma 28 | 2,849
colon cancer 25 | 1,475
primary pancreatic ductal adenocarcinoma 25 | 1,271
astrocytic glioma 24 | 2,241
pituitary cancer 24 | 1,972
primitive neuroectodermal tumor 24 | 3,031
tuberculosis 23 | 1,563
breast carcinoma 22 | 1,614
ependymoma 22 | 2,514
medulloblastoma 22 | 1,524
Pick disease 21 | 1,893
adrenocortical carcinoma 21 | 1,427
diabetes mellitus 21 | 1,663
acute quadriplegic myopathy 20 | 1,157
cystic fibrosis 20 | 1,670
ductal carcinoma in situ 20 | 1,745
juvenile dermatomyositis 20 | 1,189
posterior fossa group A ependymoma 20 | 1,511
sonic hedgehog group medulloblastoma 20 | 1,482
adult high grade glioma 19 | 2,148
spina bifida 19 | 1,064
group 3 medulloblastoma 18 | 2,254
astrocytoma 17 | 1,493
group 4 medulloblastoma 17 | 1,875
posterior fossa group B ependymoma 17 | 1,530
gastric carcinoma 16 | 832
cutaneous lupus erythematosus 15 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
Duchenne muscular dystrophy 14 | 602
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 499
Kidney disease 13 | 397
atypical teratoid/rhabdoid tumor 13 | 1,095
Atopic dermatitis 12 | 944
Alzheimer's disease 11 | 644
Rheumatoid Arthritis 11 | 1,171
aldosterone-producing adenoma 11 | 664
esophageal adenocarcinoma 11 | 737
nasopharyngeal carcinoma 11 | 1,056
pancreatic carcinoma 11 | 567
primary Sjogren syndrome 11 | 789
Down syndrome 10 | 548
Neoplasm Invasiveness 10 | 127
dermatomyositis 10 | 967
mucosa-associated lymphoid tissue lymphoma 10 | 480
IGA Glomerulonephritis 9 | 454
Multiple Sclerosis 9 | 498
Multiple myeloma 9 | 1,328
Obesity 8 | 616
Waldenstrons macroglobulinemia 8 | 765
active Crohn's disease 8 | 918
gastric cancer 8 | 436
hepatocellular carcinoma 8 | 550
progressive supranuclear palsy 8 | 674
sarcoidosis 8 | 368
Aarskog-Scott syndrome 7 | 11
Mammary Neoplasms 7 | 410
Prostatic Neoplasms 7 | 471
Stomach Neoplasms 7 | 282
Adenoma 6 | 165
Autistic Disorder 6 | 320
Intellectual disability 6 | 573
Kidney cancer 6 | 121
Neurodegenerative disease 6 | 383
Polycystic Ovary Syndrome 6 | 335
Schizophrenia 6 | 503
fibroadenoma 6 | 557
non primary Sjogren syndrome sicca 6 | 840
non-inflammatory breast cancer 6 | 208
tuberculosis and treatment for 6 months 6 | 686
Amyotrophic Lateral Sclerosis 5 | 432
Arthritis 5 | 248
Becker muscular dystrophy 5 | 187
Disease Progression 5 | 125
Liver carcinoma 5 | 217
acute myeloid leukemia 5 | 785
chronic lymphosyte leukemia 5 | 232

Tissue

Blood and immune system 146 | 17,995
Cardiovascular System 146 | 17,958
Digestive Tract 146 | 18,473
Endocrine System 146 | 18,512
Female tissues 146 | 18,647
Liver and Pancreas 146 | 18,136
Nervous System 146 | 18,561
Urinary Tract 146 | 18,444
Male tissues 145 | 17,969
Respiratory system 145 | 17,484
Skin and soft tissues 143 | 18,115

Target Family

Non-IDG 103 | 11,969
Enzyme 27 | 4,146
Kinase 16 | 634
Transporter 2 | 473
GPCR 1 | 408
Ion Channel 1 | 341

Compartment GO Term

Ruffle 150 | 150
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha PIP5K1A Tbio Kinase -0.55632 4.98 106
Unconventional myosin-Va MYO5A Tbio Non-IDG -1.72093 48.8 66
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.05927 116.0 218
Talin-1 TLN1 Tbio Non-IDG -1.88948 80.4 340
Fermitin family homolog 1 FERMT1 Tbio Non-IDG -1.92036 85.8 113
Myotubularin MTM1 Tbio Enzyme -2.68869 487.9 217
Wiskott-Aldrich syndrome protein WAS Tbio Non-IDG -3.08376 1138.7 279
Arfaptin-2 ARFIP2 Tbio Non-IDG -2.01649 99.7 152
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.59105 344.4 405
Adenomatous polyposis coli protein APC Tbio Non-IDG -1.89186 64.6 443