Development Level

Tbio 37 | 11,445
Tchem 5 | 1,598
Tdark 4 | 6,588
Tclin 1 | 613

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased threshold for audito... 2 | 26
increased or absent threshold ... 2 | 101
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
increased circulating chloride... 1 | 41
increased grip strength 1 | 41
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38

Disease

Carcinoma 30 | 11,493
osteosarcoma 28 | 7,950
ovarian cancer 27 | 8,520
glioblastoma 23 | 5,792
psoriasis 22 | 6,694
atypical teratoid / rhabdoid tumor 13 | 5,112
invasive ductal carcinoma 13 | 2,951
lung cancer 13 | 4,740
medulloblastoma, large-cell 12 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Cancer 11 | 2,499
Breast cancer 10 | 3,578
ependymoma 10 | 4,679
Kidney cancer 9 | 2,613
adult high grade glioma 9 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
non-small cell lung cancer 9 | 2,890
Multiple myeloma 8 | 1,332
astrocytoma 8 | 1,146
breast carcinoma 8 | 1,638
group 3 medulloblastoma 8 | 4,104
group 4 medulloblastoma 8 | 1,855
pancreatic cancer 8 | 2,398
Astrocytoma, Pilocytic 7 | 3,081
interstitial cystitis 7 | 2,312
tuberculosis 7 | 2,010
Autosomal recessive predisposition 6 | 1,442
astrocytic glioma 6 | 2,597
ductal carcinoma in situ 6 | 1,745
oligodendroglioma 6 | 2,850
pediatric high grade glioma 6 | 1,064
subependymal giant cell astrocytoma 6 | 2,287
Cognitive delay 5 | 608
Congenital Epicanthus 5 | 177
Epilepsy 5 | 792
Global developmental delay 5 | 608
Hepatomegaly 5 | 285
Hypoplastic mandible condyle 5 | 275
Mandibular hypoplasia 5 | 275
Mental and motor retardation 5 | 608
Micrognathism 5 | 275
Muscle hypotonia 5 | 571
Short stature 5 | 531
colon cancer 5 | 1,478
diabetes mellitus 5 | 1,728
esophageal adenocarcinoma 5 | 737
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
primitive neuroectodermal tumor 5 | 3,035
Abnormality of metabolism/homeostasis 4 | 134
Acquired scoliosis 4 | 281
Cardiac Arrhythmia 4 | 103
Cardiac conduction abnormalities 4 | 78
Cleft Palate 4 | 271
Conduction disorder of the heart 4 | 79
Curvature of spine 4 | 282
Delayed Puberty 4 | 97
Diamond-Blackfan anemia 4 | 31
EKG abnormalities 4 | 78
Electrocardiogram abnormal 4 | 81
Electrocardiogram change 4 | 78
Feeding difficulties 4 | 127
Penile hypospadias 4 | 106
Pick disease 4 | 1,894
Polycystic ovary syndrome 4 | 360
Respiratory Insufficiency 4 | 132
Respiratory function loss 4 | 121
Strabismus 4 | 270
Triangular face 4 | 58
Uranostaphyloschisis 4 | 167
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
lung carcinoma 4 | 2,843
pituitary cancer 4 | 1,972
spina bifida 4 | 1,074
Anteverted nostril 3 | 191
Atopic dermatitis 3 | 952
Broad flat nasal bridge 3 | 236
Byzanthine arch palate 3 | 194
Concave bridge of nose 3 | 195
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Failure to gain weight 3 | 365
Low Vision 3 | 174
Myopia 3 | 176
Nasal bridge wide 3 | 236
Neoplasm Invasiveness 3 | 161
Neurodegenerative disease 3 | 414
Pediatric failure to thrive 3 | 365
Seizures 3 | 596
Stomach Neoplasms 3 | 300
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
medulloblastoma 3 | 720
pancreatic carcinoma 3 | 562
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Blood and immune system 46 | 16,909
Endocrine System 46 | 18,159
Skin and soft tissues 46 | 17,230
Cardiovascular System 45 | 15,192
Digestive Tract 45 | 17,369
Female tissues 45 | 17,400
Liver and Pancreas 45 | 16,750
Male tissues 45 | 17,142
Nervous System 45 | 16,725
Respiratory system 45 | 16,393
Urinary Tract 45 | 16,678

Target Family

Non-IDG 35 | 12,091
Enzyme 10 | 4,145
Kinase 2 | 634

Compartment GO Term

Rough endoplasmic reticulum me... 47 | 47
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor receptor substrate 3 FRS3 Tbio Non-IDG -0.92119 9.61 156
Sorting and assembly machinery component 50 homolog SAMM50 Tbio Non-IDG -2.09079 120.9 124
GRB2-associated-binding protein 3 GAB3 Tbio Non-IDG -0.78182 5.77 104
GRB2-associated-binding protein 1 GAB1 Tbio Non-IDG -1.55563 50.4 268
Endoribonuclease ZC3H12A ZC3H12A Tbio Enzyme -1.81028 77.8 134
40S ribosomal protein S26 RPS26 Tbio Non-IDG -1.58194 37.1 71
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 RPN1 Tbio Enzyme -2.17901 146.5 319
60S ribosomal protein L27 RPL27 Tbio Non-IDG -1.69222 47.0 135
40S ribosomal protein S28 RPS28 Tbio Non-IDG -1.17921 14.2 44
40S ribosomal protein S29 RPS29 Tbio Non-IDG -1.11241 13.2 43