Development Level

Tbio 43 | 10,625
Tchem 9 | 1,890
Tdark 5 | 7,003
Tclin 2 | 602

IMPC Phenotype

abnormal behavior 3 | 226
preweaning lethality, complete... 3 | 633
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased grip strength 2 | 123
embryonic lethality prior to t... 2 | 187
increased grip strength 2 | 83
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal joint morphology 1 | 14
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 100
abnormal scapula morphology 1 | 3
abnormal spine curvature 1 | 7
abnormal tail morphology 1 | 17
abnormal ulna morphology 1 | 8
absent pinna reflex 1 | 21
cyanosis 1 | 6
decreased CD8-positive, alpha-... 1 | 26
decreased basophil cell number 1 | 11
decreased caudal vertebrae num... 1 | 49
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased fasted circulating g... 1 | 49
decreased kidney weight 1 | 7
decreased lean body mass 1 | 195
decreased mean corpuscular vol... 1 | 50
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
decreased vertical activity 1 | 22
edema 1 | 11
embryonic lethality prior to o... 1 | 148
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating free fat... 1 | 17
increased circulating glycerol... 1 | 11
increased or absent threshold ... 1 | 128
kyphosis 1 | 5
limb grasping 1 | 35
preweaning lethality, incomple... 1 | 260
respiratory system phenotype 1 | 2

Disease

ovarian cancer 37 | 8,491
osteosarcoma 32 | 7,933
glioblastoma 26 | 5,572
psoriasis 26 | 6,685
medulloblastoma, large-cell 22 | 6,234
Cancer 19 | 2,346
invasive ductal carcinoma 18 | 2,950
pediatric high grade glioma 18 | 2,712
pilocytic astrocytoma 16 | 3,086
atypical teratoid / rhabdoid tumor 15 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
lung adenocarcinoma 15 | 2,714
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
non-small cell lung cancer 14 | 2,798
interstitial cystitis 13 | 2,299
lung cancer 13 | 4,473
pancreatic cancer 13 | 2,300
Multiple myeloma 12 | 1,327
breast carcinoma 12 | 1,614
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Breast cancer 11 | 3,098
malignant mesothelioma 11 | 3,163
diabetes mellitus 10 | 1,663
group 4 medulloblastoma 10 | 1,875
pituitary cancer 10 | 1,972
subependymal giant cell astrocytoma 10 | 2,287
astrocytoma 9 | 1,493
ductal carcinoma in situ 9 | 1,745
primitive neuroectodermal tumor 9 | 3,031
Alzheimer's disease 8 | 644
astrocytic glioma 8 | 2,241
cystic fibrosis 8 | 1,670
ependymoma 8 | 2,514
oligodendroglioma 8 | 2,849
primary pancreatic ductal adenocarcinoma 8 | 1,271
ulcerative colitis 8 | 2,087
Kidney disease 7 | 397
esophageal adenocarcinoma 7 | 737
group 3 medulloblastoma 7 | 2,254
juvenile dermatomyositis 7 | 1,189
posterior fossa group A ependymoma 7 | 1,511
tuberculosis 7 | 1,563
Carcinoma 6 | 2,147
Obesity 6 | 616
Pick disease 6 | 1,893
Polycystic Ovary Syndrome 6 | 334
adrenocortical carcinoma 6 | 1,427
colon cancer 6 | 1,475
dermatomyositis 6 | 966
fibroadenoma 6 | 557
lung carcinoma 6 | 2,844
Heart failure 5 | 80
Hypertension 5 | 293
Hyperthyroidism 5 | 50
Hypoglycemia 5 | 81
Hypothyroidism 5 | 89
adult high grade glioma 5 | 2,148
atypical teratoid/rhabdoid tumor 5 | 1,095
sonic hedgehog group medulloblastoma 5 | 1,482
Adenoma 4 | 165
Arthritis 4 | 248
Asthma 4 | 349
Bipolar Disorder 4 | 266
Brain disease 4 | 84
Dementia 4 | 129
Down syndrome 4 | 548
Fatty liver disease 4 | 86
Heart disease 4 | 279
Hyperglycemia 4 | 120
Hypersensitivity reaction type II disease 4 | 235
Hypotension 4 | 53
Liver disease 4 | 219
Metabolic syndrome X 4 | 155
Osteoporosis 4 | 259
Prostatic Neoplasms 4 | 471
Rheumatoid Arthritis 4 | 1,170
Schizophrenia 4 | 503
active Crohn's disease 4 | 918
acute quadriplegic myopathy 4 | 1,157
gastric carcinoma 4 | 832
interstitial lung disease 4 | 292
medulloblastoma 4 | 1,524
pancreatic carcinoma 4 | 567
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064
Allergic hypersensitivity disease 3 | 123
Cerebrovascular disease 3 | 231
Coronary artery disease 3 | 240
Hyperandrogenism 3 | 32
Hypertensive disease 3 | 193
IGA Glomerulonephritis 3 | 454
Lipid metabolism disorder 3 | 102
Lung disease 3 | 136
Multiple Sclerosis 3 | 498
Vascular disease 3 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic lymphosyte leukemia 3 | 232
hepatocellular carcinoma 3 | 550
tuberculosis and treatment for 6 months 3 | 686

Tissue

Male tissues 59 | 17,968
Blood and immune system 58 | 17,994
Digestive Tract 58 | 18,472
Endocrine System 58 | 18,511
Female tissues 58 | 18,646
Nervous System 58 | 18,560
Skin and soft tissues 58 | 18,114
Urinary Tract 58 | 18,443
Cardiovascular System 57 | 17,957
Liver and Pancreas 57 | 18,135
Respiratory system 56 | 17,483

Target Family

Non-IDG 39 | 11,969
Enzyme 16 | 4,146
Kinase 3 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Rough endoplasmic reticulum 59 | 59
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.73976 5495.0 809
Fibroblast growth factor receptor substrate 3 FRS3 Tbio Non-IDG -0.89335 9.09 133
Nesprin-3 SYNE3 Tbio Non-IDG -0.90535 8.74 91
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.43730 28.2 91
Endoribonuclease ZC3H12A ZC3H12A Tbio Enzyme -1.74006 69.5 117
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 RPN1 Tbio Enzyme -2.15344 139.1 249
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 RPN2 Tbio Enzyme -1.46978 30.0 91
Orexin HCRT Tbio Non-IDG -3.24848 2104.5 162
Translocating chain-associated membrane protein 1 TRAM1 Tdark Non-IDG -0.44494 3.72 83
Breast cancer anti-estrogen resistance protein 1 BCAR1 Tbio Non-IDG -2.38651 211.2 490