Development Level

Tbio 55 | 11,651
Tchem 7 | 1,388
Tdark 3 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
decreased startle reflex 2 | 75
decreased threshold for audito... 2 | 26
decreased vertical activity 2 | 208
increased or absent threshold ... 2 | 101
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal limb morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal tail morphology 1 | 25
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating glycerol... 1 | 16
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased grip strength 1 | 41
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
pallor 1 | 34
prolonged QT interval 1 | 38
respiratory system phenotype 1 | 2

Disease

ovarian cancer 41 | 8,520
Carcinoma 40 | 11,493
osteosarcoma 36 | 7,950
glioblastoma 32 | 5,792
psoriasis 29 | 6,694
medulloblastoma, large-cell 23 | 6,241
atypical teratoid / rhabdoid tumor 21 | 5,112
Cancer 20 | 2,499
invasive ductal carcinoma 19 | 2,951
lung cancer 18 | 4,740
adult high grade glioma 16 | 3,801
ependymoma 16 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
lung adenocarcinoma 16 | 2,716
non-small cell lung cancer 15 | 2,890
Astrocytoma, Pilocytic 14 | 3,081
Breast cancer 14 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
group 3 medulloblastoma 13 | 4,104
interstitial cystitis 13 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
pancreatic cancer 13 | 2,398
Kidney cancer 12 | 2,613
Multiple myeloma 12 | 1,332
breast carcinoma 12 | 1,638
diabetes mellitus 12 | 1,728
malignant mesothelioma 12 | 3,232
tuberculosis 12 | 2,010
Autosomal recessive predisposition 11 | 1,442
group 4 medulloblastoma 11 | 1,855
pituitary cancer 11 | 1,972
subependymal giant cell astrocytoma 11 | 2,287
astrocytoma 10 | 1,146
ductal carcinoma in situ 10 | 1,745
primitive neuroectodermal tumor 10 | 3,035
Alzheimer's disease 9 | 658
Epilepsy 9 | 792
cystic fibrosis 9 | 1,696
oligodendroglioma 9 | 2,850
Obesity 8 | 678
astrocytic glioma 8 | 2,597
juvenile dermatomyositis 8 | 1,187
pediatric high grade glioma 8 | 1,064
Kidney disease 7 | 430
Pick disease 7 | 1,894
Schizophrenia 7 | 1,160
adrenocortical carcinoma 7 | 1,428
colon cancer 7 | 1,478
dermatomyositis 7 | 966
esophageal adenocarcinoma 7 | 737
Heart failure 6 | 162
Liver Cirrhosis, Experimental 6 | 769
Osteoporosis 6 | 363
Polycystic ovary syndrome 6 | 360
fibroadenoma 6 | 559
lung carcinoma 6 | 2,843
primary pancreatic ductal adenocarcinoma 6 | 1,109
ulcerative colitis 6 | 1,819
Acquired scoliosis 5 | 281
Arthritis 5 | 290
Bipolar Disorder 5 | 666
Cognitive delay 5 | 608
Curvature of spine 5 | 282
Dementia 5 | 175
Fatigue 5 | 182
Global developmental delay 5 | 608
Heart disease 5 | 306
Hyperinsulinism 5 | 133
Hypertension 5 | 396
Hyperthyroidism 5 | 53
Hypoglycemia 5 | 152
Hypogonadism 5 | 173
Hypothyroidism 5 | 122
Intellectual disability 5 | 1,016
Mental and motor retardation 5 | 608
Muscle hypotonia 5 | 571
Neurodegenerative disease 5 | 414
Seizures 5 | 596
active Crohn's disease 5 | 922
acute quadriplegic myopathy 5 | 1,158
progressive supranuclear palsy 5 | 676
spina bifida 5 | 1,074
Adenoma 4 | 167
Anemia 4 | 365
Anteverted nostril 4 | 191
Asthma 4 | 385
Cerebrovascular disease 4 | 238
Depressive disorder 4 | 409
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Glaucoma 4 | 239
Hepatomegaly 4 | 285
Hypersensitivity reaction type II disease 4 | 253
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
Stomach Neoplasms 4 | 300
Waldenstrons macroglobulinemia 4 | 765
hepatocellular carcinoma 4 | 547
pancreatic carcinoma 4 | 562

Tissue

Skin and soft tissues 66 | 17,230
Digestive Tract 65 | 17,369
Endocrine System 65 | 18,159
Blood and immune system 64 | 16,909
Female tissues 64 | 17,400
Liver and Pancreas 63 | 16,750
Male tissues 63 | 17,142
Nervous System 63 | 16,725
Respiratory system 63 | 16,393
Urinary Tract 63 | 16,678
Cardiovascular System 62 | 15,192

Target Family

Non-IDG 46 | 12,091
Enzyme 17 | 4,145
Kinase 3 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Rough endoplasmic reticulum 67 | 67
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Signal recognition particle receptor subunit beta SRPRB Tdark Non-IDG -0.45047 3.90 198
Double-stranded RNA-binding protein Staufen homolog 1 STAU1 Tbio Non-IDG -2.24156 174.1 258
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 Tbio Enzyme -2.10120 119.8 88
Signal recognition particle 9 kDa protein SRP9 Tbio Non-IDG -1.52679 31.8 33
Orexin HCRT Tbio Non-IDG -3.27696 2001.9 203
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 RPN2 Tbio Enzyme -1.51340 29.9 118
Pro-opiomelanocortin POMC Tbio Non-IDG -4.56004 36591.2 1334
Fibroblast growth factor receptor substrate 2 FRS2 Tbio Non-IDG -2.37203 224.0 344
Sigma intracellular receptor 2 TMEM97 Tbio Non-IDG -1.27501 19.8 67
Ran guanine nucleotide release factor RANGRF Tbio Enzyme -1.33723 22.7 35