Development Level

Tchem 10 | 1,890
Tbio 3 | 10,625

IMPC Phenotype

abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
absent vibrissae 1 | 14
decreased bone mineral content 1 | 157
embryonic lethality prior to t... 1 | 187
oligodactyly 1 | 14
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
small superior vagus ganglion 1 | 20

Disease

Cancer 10 | 2,346
ovarian cancer 8 | 8,491
lung cancer 7 | 4,473
lung carcinoma 7 | 2,844
psoriasis 7 | 6,685
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
glioblastoma 5 | 5,572
interstitial cystitis 5 | 2,299
osteosarcoma 5 | 7,933
cutaneous lupus erythematosus 4 | 1,056
ulcerative colitis 4 | 2,087
Autoimmune Lymphoproliferative Syndrome 3 | 12
Leukemia 3 | 88
Stomach Neoplasms 3 | 282
active Crohn's disease 3 | 918
atypical teratoid / rhabdoid tumor 3 | 4,369
group 4 medulloblastoma 3 | 1,875
malignant mesothelioma 3 | 3,163
non-small cell lung cancer 3 | 2,798
pancreatic cancer 3 | 2,300
pilocytic astrocytoma 3 | 3,086
tuberculosis 3 | 1,563
Alzheimer's disease 2 | 644
Bipolar Disorder 2 | 266
Brain Ischemia 2 | 87
Breast cancer 2 | 3,098
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
HIV Infections 2 | 99
Melanoma 2 | 261
Myocardial Reperfusion Injury 2 | 34
Pick disease 2 | 1,893
Reperfusion Injury 2 | 84
Skin Neoplasms 2 | 49
Type 2 diabetes mellitus 2 | 192
Vascular disease 2 | 281
cystic fibrosis 2 | 1,670
dermatomyositis 2 | 966
hepatocellular carcinoma 2 | 550
medulloblastoma, large-cell 2 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 1,511
posterior fossa group B ependymoma 2 | 1,530
primary Sjogren syndrome 2 | 788
spina bifida 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
Acquired metabolic disease 1 | 267
Adenocarcinoma 1 | 115
Amyloidosis 1 | 68
Amyotrophic Lateral Sclerosis 1 | 432
Anorexia 1 | 15
Autoimmune Diseases 1 | 33
Bladder Neoplasm 1 | 109
Calcinosis 1 | 63
Cerebral Hemorrhage 1 | 27
Colorectal Neoplasms 1 | 217
Craniofacial Abnormalities 1 | 147
Diabetes Mellitus, Experimental 1 | 106
Edema 1 | 38
Edwards syndrome 1 | 15
Esophageal Neoplasms 1 | 67
Esophageal cancer 1 | 30
Exanthem 1 | 39
Fatty Liver 1 | 48
Gaucher disease type 1 1 | 171
Heart failure 1 | 80
Heart valve disease 1 | 24
Hodgkin Disease 1 | 16
Huntington disease 1 | 12
Hypersensitivity 1 | 63
Inflammatory bowel disease 1 | 142
Kidney disease 1 | 397
Liver carcinoma 1 | 217
Liver disease 1 | 219
Lung Neoplasms 1 | 171
Lung disease 1 | 136
Lymphoma, Non-Hodgkin 1 | 22
MALT lymphoma 1 | 5
MYELODYSPLASTIC SYNDROME 1 | 39
Mammary Neoplasms 1 | 410
Neoplasm Metastasis 1 | 138
Neoplasm of stomach 1 | 11
Neurodegenerative disease 1 | 383
Nonsyndromic deafness 1 | 121
Pancreatic Neoplasm 1 | 79
Parkinson's disease 1 | 364
Pericarditis 1 | 14
Pneumonia 1 | 133
Pulmonary Embolism 1 | 45
Rift Valley fever 1 | 13
Squamous cell carcinoma of the head and neck 1 | 24
Status Epilepticus 1 | 85
Stomach cancer 1 | 18
Toxic encephalopathy 1 | 131
Uterine Cervical Neoplasm 1 | 21
Vitiligo 1 | 71
active ulcerative colitis 1 | 477
glioblastoma multiforme 1 | 347
non-small cell lung carcinoma 1 | 413
systemic lupus erythematosus 1 | 172

Tissue

Blood and immune system 13 | 17,994
Cardiovascular System 13 | 17,957
Digestive Tract 13 | 18,472
Endocrine System 13 | 18,511
Female tissues 13 | 18,646
Liver and Pancreas 13 | 18,135
Male tissues 13 | 17,968
Nervous System 13 | 18,560
Respiratory system 13 | 17,483
Skin and soft tissues 13 | 18,114
Urinary Tract 13 | 18,443

Target Family

Non-IDG 7 | 11,969
Enzyme 3 | 4,146
Kinase 3 | 634

Compartment GO Term

Ripoptosome 13 | 13
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Receptor-interacting serine/threonine-protein kinase 3 RIPK3 Tchem Kinase -2.11581 129.5 456
Neuroendocrine convertase 1 PCSK1 Tchem Enzyme -2.30329 186.2 119
FAS-associated death domain protein FADD Tbio Non-IDG -2.68548 451.9 595
Diablo homolog, mitochondrial DIABLO Tbio Non-IDG -2.92513 912.9 449
CASP8 and FADD-like apoptosis regulator CFLAR Tchem Non-IDG -2.87761 837.3 538
Caspase-10 CASP10 Tchem Enzyme -1.96385 86.0 434
TIR domain-containing adapter molecule 1 TICAM1 Tbio Non-IDG -1.46541 31.8 191
Mixed lineage kinase domain-like protein MLKL Tchem Kinase -2.70535 486.1 118
Caspase-8 CASP8 Tchem Enzyme -3.51864 2954.7 930
Receptor-interacting serine/threonine-protein kinase 1 RIPK1 Tchem Kinase -2.23391 169.4 285