Development Level

Tbio 184 | 10,625
Tdark 85 | 7,003
Tchem 28 | 1,890
Tclin 11 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 10 | 633
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 3 | 187
abnormal bone structure 2 | 131
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
abnormal seminal vesicle morph... 2 | 47
decreased circulating glucose ... 2 | 121
decreased lean body mass 2 | 195
embryonic growth retardation 2 | 28
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
abnormal bone mineralization 1 | 55
abnormal coat appearance 1 | 25
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal kidney morphology 1 | 30
abnormal lumbar vertebrae morp... 1 | 6
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
corneal opacity 1 | 25
decreased CD11b-low dendritic ... 1 | 3
decreased Ly6C high monocyte n... 1 | 18
decreased T-helper cell number 1 | 4
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating creatini... 1 | 31
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased monocyte cell number 1 | 28
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased CD11b-high dendritic... 1 | 5
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating total pr... 1 | 20
increased effector memory CD4-... 1 | 15
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean platelet volume 1 | 19
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
short snout 1 | 4
vertebral transformation 1 | 12

Disease

ovarian cancer 158 | 8,484
osteosarcoma 104 | 7,933
lung cancer 93 | 4,466
medulloblastoma, large-cell 72 | 6,234
psoriasis 67 | 6,685
Multiple myeloma 65 | 1,327
diabetes mellitus 52 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 52 | 3,289
glioblastoma 50 | 5,572
Cancer 46 | 2,346
atypical teratoid / rhabdoid tumor 43 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,956
Breast cancer 35 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,988
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,795
non-small cell lung cancer 31 | 2,798
acute quadriplegic myopathy 30 | 1,157
malignant mesothelioma 30 | 3,162
sonic hedgehog group medulloblastoma 30 | 1,482
group 3 medulloblastoma 29 | 2,254
pediatric high grade glioma 27 | 2,712
Waldenstrons macroglobulinemia 26 | 765
Diamond-Blackfan anemia 25 | 28
acute myeloid leukemia 25 | 780
colon cancer 25 | 1,475
oligodendroglioma 25 | 2,849
subependymal giant cell astrocytoma 25 | 2,287
astrocytoma 24 | 1,493
lung adenocarcinoma 24 | 2,713
Mammary Neoplasms 23 | 410
cystic fibrosis 23 | 1,665
primitive neuroectodermal tumor 23 | 3,031
ependymoma 22 | 2,514
invasive ductal carcinoma 22 | 2,950
pilocytic astrocytoma 21 | 3,086
astrocytic glioma 20 | 2,241
pancreatic cancer 19 | 2,300
adult high grade glioma 18 | 2,148
non primary Sjogren syndrome sicca 18 | 840
Stomach Neoplasms 16 | 282
group 4 medulloblastoma 16 | 1,875
Anemia 15 | 252
primary pancreatic ductal adenocarcinoma 15 | 1,271
Disease Progression 14 | 125
Pick disease 14 | 1,893
posterior fossa group A ependymoma 14 | 1,511
Neurodegenerative disease 13 | 383
lung carcinoma 13 | 2,844
medulloblastoma 13 | 1,524
Anemia, Diamond-Blackfan 12 | 15
Leber hereditary optic neuropathy 12 | 17
Mitochondrial myopathy 12 | 23
Carcinoma 11 | 2,147
Vascular disease 11 | 281
breast carcinoma 11 | 1,614
dermatomyositis 11 | 933
mucosa-associated lymphoid tissue lymphoma 11 | 480
Leigh disease 10 | 81
Optic Atrophy, Hereditary, Leber 10 | 14
Prostatic Neoplasms 10 | 471
adrenocortical carcinoma 10 | 1,427
atypical teratoid/rhabdoid tumor 10 | 1,095
juvenile dermatomyositis 10 | 1,189
tuberculosis and treatment for 6 months 10 | 686
Diabetes mellitus type 2 9 | 69
Kidney disease 9 | 396
Melanoma 9 | 261
Schizophrenia 9 | 501
glioblastoma multiforme 9 | 347
inflammatory breast cancer 9 | 404
Alzheimer's disease 8 | 644
Duchenne muscular dystrophy 8 | 602
Heart disease 8 | 279
Liver carcinoma 8 | 217
Mammary Neoplasms, Experimental 8 | 150
Obesity 8 | 616
Rheumatoid Arthritis 8 | 1,160
Treatment Refractory Type 2 Diabetes Mellitus 8 | 53
Animal Mammary Neoplasms 7 | 136
Down syndrome 7 | 548
Epilepsy 7 | 346
Lactic acidosis 7 | 42
MITOCHONDRIAL COMPLEX I DEFICIENCY 7 | 37
Osteoporosis 7 | 257
active Crohn's disease 7 | 918
hereditary spastic paraplegia 7 | 313
posterior fossa group B ependymoma 7 | 1,530
progressive supranuclear palsy 7 | 674
ulcerative colitis 7 | 2,087
Amyotrophic Lateral Sclerosis 6 | 431
Intellectual disability 6 | 573
Lung Neoplasms 6 | 171
Malaria 6 | 140
Neuropathy 6 | 210
Polycystic Ovary Syndrome 6 | 332
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
cutaneous lupus erythematosus 6 | 1,056
nasopharyngeal carcinoma 6 | 1,056
pituitary cancer 6 | 1,972
tuberculosis 6 | 1,557

Tissue

Cardiovascular System 303 | 17,958
Digestive Tract 303 | 18,473
Female tissues 303 | 18,647
Nervous System 303 | 18,561
Urinary Tract 303 | 18,444
Blood and immune system 302 | 17,995
Endocrine System 302 | 18,512
Liver and Pancreas 301 | 18,136
Male tissues 301 | 17,969
Respiratory system 299 | 17,484
Skin and soft tissues 299 | 18,115

Target Family

Non-IDG 240 | 11,971
Enzyme 41 | 4,146
Kinase 14 | 634
Transcription Factor 7 | 1,400
Epigenetic 3 | 242
Transporter 2 | 473
Nuclear Receptor 1 | 48

Compartment GO Term

Ribosome 308 | 308
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NADH-ubiquinone oxidoreductase chain 6 MT-ND6 Tclin Enzyme -2.74395 585.6 62
ATP synthase protein 8 MT-ATP8 Tbio Enzyme -2.30895 191.4 20
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
39S ribosomal protein L37, mitochondrial MRPL37 Tdark Non-IDG -0.30103 2.00 47
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Cytochrome b MT-CYB Tbio Non-IDG -3.74473 5676.0 122
60S ribosomal protein L7a RPL7A Tbio Non-IDG -1.66015 45.9 60
60S ribosomal protein L18 RPL18 Tbio Non-IDG -1.73537 50.7 134
39S ribosomal protein L19, mitochondrial MRPL19 Tbio Non-IDG -0.91149 8.14 108
Neuroguidin NGDN Tbio Non-IDG -2.18414 121.6 78