Development Level

Tbio 135 | 10,625
Tdark 74 | 7,003
Tchem 9 | 1,890
Tclin 1 | 602

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 633
embryonic lethality prior to o... 3 | 148
embryonic lethality prior to t... 2 | 187
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal embryo size 1 | 112
abnormal lens morphology 1 | 73
abnormal seminal vesicle morph... 1 | 47
abnormal spleen morphology 1 | 36
decreased CD11b-low dendritic ... 1 | 3
decreased circulating glucose ... 1 | 121
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
embryonic growth retardation 1 | 28
enlarged heart 1 | 111
increased CD11b-high dendritic... 1 | 5
increased circulating creatini... 1 | 29
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 105 | 8,491
lung cancer 69 | 4,473
osteosarcoma 58 | 7,933
Multiple myeloma 45 | 1,327
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,289
medulloblastoma, large-cell 40 | 6,234
diabetes mellitus 36 | 1,663
psoriasis 32 | 6,685
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,795
glioblastoma 26 | 5,572
sonic hedgehog group medulloblastoma 26 | 1,482
Diamond-Blackfan anemia 25 | 30
Breast cancer 23 | 3,098
atypical teratoid / rhabdoid tumor 23 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
Waldenstrons macroglobulinemia 21 | 764
malignant mesothelioma 21 | 3,163
non-small cell lung cancer 21 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
acute myeloid leukemia 19 | 785
Cancer 18 | 2,346
Mammary Neoplasms 17 | 410
acute quadriplegic myopathy 17 | 1,157
colon cancer 17 | 1,475
cystic fibrosis 16 | 1,670
group 3 medulloblastoma 16 | 2,254
lung adenocarcinoma 16 | 2,714
non primary Sjogren syndrome sicca 15 | 840
oligodendroglioma 14 | 2,849
pediatric high grade glioma 14 | 2,712
subependymal giant cell astrocytoma 14 | 2,287
invasive ductal carcinoma 13 | 2,950
Anemia, Diamond-Blackfan 12 | 15
Stomach Neoplasms 12 | 282
Disease Progression 11 | 125
astrocytic glioma 11 | 2,241
Anemia 10 | 252
astrocytoma 10 | 1,493
primitive neuroectodermal tumor 10 | 3,031
pilocytic astrocytoma 9 | 3,086
adult high grade glioma 8 | 2,148
hereditary spastic paraplegia 8 | 313
inflammatory breast cancer 8 | 404
dermatomyositis 7 | 966
ependymoma 7 | 2,514
lung carcinoma 7 | 2,844
mucosa-associated lymphoid tissue lymphoma 7 | 480
posterior fossa group A ependymoma 7 | 1,511
atypical teratoid/rhabdoid tumor 6 | 1,095
breast carcinoma 6 | 1,614
pancreatic cancer 6 | 2,300
Duchenne muscular dystrophy 5 | 602
Osteoporosis 5 | 259
Shwachman-Diamond syndrome 5 | 16
adrenocortical carcinoma 5 | 1,427
glioblastoma multiforme 5 | 347
juvenile dermatomyositis 5 | 1,189
medulloblastoma 5 | 1,524
primary pancreatic ductal adenocarcinoma 5 | 1,271
tuberculosis and treatment for 6 months 5 | 686
Animal Mammary Neoplasms 4 | 135
Mammary Neoplasms, Experimental 4 | 149
Neurodegenerative disease 4 | 383
Parkinson Disease 4 | 105
Pick disease 4 | 1,893
Rheumatoid Arthritis 4 | 1,170
active Crohn's disease 4 | 918
nasopharyngeal carcinoma 4 | 1,056
posterior fossa group B ependymoma 4 | 1,530
spina bifida 4 | 1,064
ulcerative colitis 4 | 2,087
Brain glioma 3 | 10
Carcinoma 3 | 2,147
Down syndrome 3 | 548
HIV Infections 3 | 99
Heart disease 3 | 279
Hypertension 3 | 293
Intellectual disability 3 | 573
Irregular astigmatism 3 | 11
Kidney disease 3 | 397
Lacrimal gland carcinoma 3 | 5
Neoplasm Invasiveness 3 | 127
Neoplasm Metastasis 3 | 138
Polycystic Ovary Syndrome 3 | 334
Prostatic Neoplasms 3 | 471
Pure red-cell aplasia 3 | 4
Renal Cell Carcinoma 3 | 199
Schizophrenia 3 | 503
Weight Gain 3 | 87
aldosterone-producing adenoma 3 | 664
cutaneous lupus erythematosus 3 | 1,056
group 4 medulloblastoma 3 | 1,875
non diabetic and post-ischemic heart failure 3 | 200
tuberculosis 3 | 1,563
Atherosclerosis 2 | 275
Coronary artery disease 2 | 240
Multiple Sclerosis 2 | 498
Myocardial Ischemia 2 | 169
hepatocellular carcinoma 2 | 550
pituitary cancer 2 | 1,972

Tissue

Cardiovascular System 215 | 17,957
Digestive Tract 215 | 18,472
Female tissues 215 | 18,646
Liver and Pancreas 215 | 18,135
Nervous System 215 | 18,560
Urinary Tract 215 | 18,443
Blood and immune system 214 | 17,994
Endocrine System 214 | 18,511
Male tissues 214 | 17,968
Respiratory system 214 | 17,483
Skin and soft tissues 211 | 18,114

Target Family

Non-IDG 204 | 11,969
Enzyme 12 | 4,146
Epigenetic 2 | 242
Kinase 1 | 634

Compartment GO Term

Ribosomal subunit 219 | 219
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.47495 286.5 135
28S ribosomal protein S18a, mitochondrial MRPS18A Tdark Non-IDG 0.32 0.72 46
Ribosomal biogenesis protein LAS1L LAS1L Tdark Non-IDG -0.45120 2.84 94
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.12258 1305.7 243
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.50018 27956.4 30
60S ribosomal protein L13a RPL13A Tbio Non-IDG -1.62587 63.2 46
Fragile X mental retardation syndrome-related protein 2 FXR2 Tbio Epigenetic -1.34346 15.8 209
40S ribosomal protein S7 RPS7 Tbio Non-IDG -1.83618 67.7 104
Eukaryotic translation initiation factor 2A EIF2A Tbio Non-IDG -0.57210 3.87 227
60S ribosomal protein L38 RPL38 Tdark Non-IDG -1.39373 24.2 45