Development Level

Tbio 133 | 11,651
Tdark 67 | 6,593
Tchem 5 | 1,388
Tclin 1 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 15 | 979
embryonic lethality prior to o... 9 | 239
embryonic lethality prior to t... 4 | 278
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal lens morphology 2 | 81
abnormal spleen morphology 2 | 55
decreased vertical activity 2 | 208
enlarged heart 2 | 210
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
cataract 1 | 92
decreased circulating glucose ... 1 | 126
enlarged spleen 1 | 41
hemorrhage 1 | 23
impaired pupillary reflex 1 | 26
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
prolonged QT interval 1 | 38
short tibia 1 | 97

Disease

ovarian cancer 100 | 8,520
lung cancer 66 | 4,740
osteosarcoma 59 | 7,950
Carcinoma 55 | 11,493
Multiple myeloma 40 | 1,332
medulloblastoma, large-cell 39 | 6,241
diabetes mellitus 33 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
psoriasis 31 | 6,694
glioblastoma 28 | 5,792
atypical teratoid / rhabdoid tumor 24 | 5,112
Breast cancer 23 | 3,578
malignant mesothelioma 22 | 3,232
non-small cell lung cancer 22 | 2,890
Diamond-Blackfan anemia 21 | 31
group 3 medulloblastoma 21 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Cancer 18 | 2,499
Waldenstrons macroglobulinemia 18 | 765
Breast Neoplasms 17 | 445
Mammary Neoplasms 17 | 425
acute myeloid leukemia 17 | 783
Anemia 16 | 365
sonic hedgehog group medulloblastoma 16 | 467
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
non primary Sjogren syndrome sicca 15 | 891
oligodendroglioma 15 | 2,850
colon cancer 14 | 1,478
acute quadriplegic myopathy 13 | 1,158
ependymoma 13 | 4,679
lung adenocarcinoma 13 | 2,716
Cleft Palate 12 | 271
Fatigue 12 | 182
Pallor 12 | 40
astrocytic glioma 12 | 2,597
cystic fibrosis 12 | 1,696
Abnormality of the urinary system 11 | 21
Anemia, Diamond-Blackfan 11 | 16
Anemia, Macrocytic 11 | 18
Cardiac Arrhythmia 11 | 103
Cardiac conduction abnormalities 11 | 78
Conduction disorder of the heart 11 | 79
Delayed Puberty 11 | 97
EKG abnormalities 11 | 78
Electrocardiogram abnormal 11 | 81
Electrocardiogram change 11 | 78
Hand deformities 11 | 32
Intermittent migraine headaches 11 | 68
Migraine Disorders 11 | 76
Uranostaphyloschisis 11 | 167
genital abnormal 11 | 17
reproductive system abnormality 11 | 17
subependymal giant cell astrocytoma 11 | 2,287
Stomach Neoplasms 10 | 300
astrocytoma 10 | 1,146
pediatric high grade glioma 10 | 1,064
Disease Progression 9 | 136
adult high grade glioma 9 | 3,801
invasive ductal carcinoma 9 | 2,951
primitive neuroectodermal tumor 9 | 3,035
Adenocarcinoma of lung 8 | 142
Astrocytoma, Pilocytic 8 | 3,081
Disease Models, Animal 8 | 155
hereditary spastic paraplegia 8 | 318
dermatomyositis 7 | 966
lung carcinoma 7 | 2,843
Intellectual disability 6 | 1,016
Kidney cancer 6 | 2,613
Shwachman-Diamond syndrome 6 | 17
mucosa-associated lymphoid tissue lymphoma 6 | 484
Autosomal recessive predisposition 5 | 1,442
Osteoporosis 5 | 363
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
group 4 medulloblastoma 5 | 1,855
inflammatory breast cancer 5 | 286
juvenile dermatomyositis 5 | 1,187
medulloblastoma 5 | 720
pancreatic cancer 5 | 2,398
Cognitive delay 4 | 608
Duchenne muscular dystrophy 4 | 601
Failure to gain weight 4 | 365
Global developmental delay 4 | 608
Hypertension 4 | 396
Hypoplastic mandible condyle 4 | 275
Mandibular hypoplasia 4 | 275
Mental and motor retardation 4 | 608
Micrognathism 4 | 275
Neurodegenerative disease 4 | 414
Pediatric failure to thrive 4 | 365
Pick disease 4 | 1,894
Rheumatoid arthritis 4 | 1,191
Short stature 4 | 531
active Crohn's disease 4 | 922
nasopharyngeal carcinoma 4 | 1,058
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819

Tissue

Endocrine System 198 | 18,159
Blood and immune system 197 | 16,909
Digestive Tract 197 | 17,369
Liver and Pancreas 197 | 16,750
Male tissues 197 | 17,142
Skin and soft tissues 197 | 17,230
Female tissues 196 | 17,400
Nervous System 196 | 16,725
Respiratory system 196 | 16,393
Urinary Tract 196 | 16,678
Cardiovascular System 195 | 15,192

Target Family

Non-IDG 191 | 12,091
Enzyme 12 | 4,145
Epigenetic 2 | 242
Kinase 1 | 634

Compartment GO Term

Ribosomal subunit 206 | 206
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eukaryotic translation initiation factor 1 EIF1 Tbio Non-IDG -2.06392 118.5 92
28S ribosomal protein S14, mitochondrial MRPS14 Tdark Non-IDG 0.30 0.11 22
39S ribosomal protein L40, mitochondrial MRPL40 Tbio Non-IDG -0.92179 8.33 105
Eukaryotic translation initiation factor 2 subunit 1 EIF2S1 Tbio Non-IDG -2.81111 643.5 577
39S ribosomal protein L42, mitochondrial MRPL42 Tdark Non-IDG 0.02 0.40 139
28S ribosomal protein S18b, mitochondrial MRPS18B Tdark Non-IDG -0.67793 4.10 45
39S ribosomal protein S18a, mitochondrial MRPS18A Tdark Non-IDG 0.32 0.72 57
60S ribosomal protein L7-like 1 RPL7L1 Tdark Non-IDG 0.41 0.39 57
39S ribosomal protein L16, mitochondrial MRPL16 Tdark Non-IDG -0.22185 1.67 71
Probable rRNA-processing protein EBP2 EBNA1BP2 Tbio Non-IDG -1.54043 34.9 87