Development Level

Tbio 121 | 10,625
Tdark 27 | 7,003
Tchem 22 | 1,890
Tclin 3 | 602

IMPC Term

preweaning lethality, complete... 11 | 633
abnormal behavior 6 | 226
preweaning lethality, incomple... 6 | 260
embryonic lethality prior to o... 4 | 148
abnormal embryo size 3 | 112
abnormal sleep behavior 3 | 63
decreased grip strength 3 | 123
embryonic lethality prior to t... 3 | 187
increased grip strength 3 | 83
abnormal retina morphology 2 | 100
absent startle reflex 2 | 15
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 121
increased fasted circulating g... 2 | 68
increased or absent threshold ... 2 | 128
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal embryo turning 1 | 15
abnormal femur morphology 1 | 14
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal skin condition 1 | 6
abnormal spine curvature 1 | 7
abnormal vocalization 1 | 21
aorta dilation 1 | 3
convulsive seizures 1 | 11
decreased IgG2b level 1 | 1
decreased NK cell number 1 | 16
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating iron lev... 1 | 25
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
decreased urine creatinine lev... 1 | 2
decreased vertical activity 1 | 22
embryonic growth retardation 1 | 28
hyperactivity 1 | 108
increased CD8-positive, alpha-... 1 | 11
increased body length 1 | 20
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating glucose ... 1 | 16
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased granulocyte number 1 | 8
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased prepulse inhibition 1 | 21
irregularly shaped pupil 1 | 7
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9

Disease

ovarian cancer 94 | 8,492
osteosarcoma 92 | 7,933
medulloblastoma, large-cell 65 | 6,234
atypical teratoid / rhabdoid tumor 58 | 4,369
glioblastoma 56 | 5,572
psoriasis 56 | 6,685
lung cancer 51 | 4,473
Cancer 37 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,289
Breast cancer 36 | 3,099
primitive neuroectodermal tumor 36 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,988
ependymoma 34 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,956
oligodendroglioma 33 | 2,849
Multiple myeloma 31 | 1,328
astrocytic glioma 29 | 2,241
subependymal giant cell astrocytoma 29 | 2,287
Pick disease 28 | 1,893
group 4 medulloblastoma 28 | 1,875
juvenile dermatomyositis 27 | 1,189
Carcinoma 26 | 2,147
acute quadriplegic myopathy 25 | 1,157
pediatric high grade glioma 25 | 2,712
lung adenocarcinoma 24 | 2,714
malignant mesothelioma 23 | 3,163
pancreatic cancer 23 | 2,300
Waldenstrons macroglobulinemia 22 | 765
pilocytic astrocytoma 22 | 3,086
Amyotrophic Lateral Sclerosis 21 | 432
adult high grade glioma 21 | 2,148
dermatomyositis 21 | 967
invasive ductal carcinoma 20 | 2,950
astrocytoma 18 | 1,493
group 3 medulloblastoma 18 | 2,254
lung carcinoma 18 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,795
medulloblastoma 16 | 1,524
non-small cell lung cancer 16 | 2,798
progressive supranuclear palsy 16 | 674
sonic hedgehog group medulloblastoma 16 | 1,482
Rheumatoid Arthritis 15 | 1,171
primary pancreatic ductal adenocarcinoma 15 | 1,271
spina bifida 15 | 1,064
Neurodegenerative disease 13 | 383
adrenocortical carcinoma 13 | 1,427
atypical teratoid/rhabdoid tumor 13 | 1,095
breast carcinoma 13 | 1,614
colon cancer 13 | 1,475
diabetes mellitus 13 | 1,663
ulcerative colitis 13 | 2,087
pituitary cancer 12 | 1,972
Alzheimer's disease 11 | 644
tuberculosis and treatment for 6 months 11 | 686
cutaneous lupus erythematosus 10 | 1,056
cystic fibrosis 10 | 1,670
ductal carcinoma in situ 10 | 1,745
hepatocellular carcinoma 10 | 550
non primary Sjogren syndrome sicca 10 | 840
IGA Glomerulonephritis 9 | 454
Duchenne muscular dystrophy 8 | 602
Infertility 8 | 163
Intellectual disability 8 | 573
Male infertility 8 | 170
acute myeloid leukemia 8 | 785
primary Sjogren syndrome 8 | 789
tuberculosis 8 | 1,563
Frontotemporal dementia 7 | 47
Mammary Neoplasms 7 | 410
aldosterone-producing adenoma 7 | 664
hereditary spastic paraplegia 7 | 313
interstitial cystitis 7 | 2,299
nasopharyngeal carcinoma 7 | 1,056
posterior fossa group A ependymoma 7 | 1,511
Atopic dermatitis 6 | 944
Down syndrome 6 | 548
HIV Infections 6 | 100
Myocardial Ischemia 6 | 169
Polycystic Ovary Syndrome 6 | 335
Spinocerebellar ataxia type 2 6 | 19
active Crohn's disease 6 | 918
gastric cancer 6 | 436
gastric carcinoma 6 | 832
pancreatic carcinoma 6 | 567
sarcoidosis 6 | 368
Animal Mammary Neoplasms 5 | 136
Gaucher disease type 1 5 | 171
Mammary Neoplasms, Experimental 5 | 150
Parkinson's disease 5 | 364
Primary biliary cirrhosis 5 | 45
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
interstitial lung disease 5 | 292
posterior fossa group B ependymoma 5 | 1,530
Dementia 4 | 129
Liver carcinoma 4 | 217
Multiple Sclerosis 4 | 498
Obesity 4 | 616
Schizophrenia 4 | 503
Substance-Related Disorders 4 | 114
inflammatory breast cancer 4 | 404

Tissue

Endocrine System 171 | 18,512
Female tissues 171 | 18,647
Male tissues 171 | 17,969
Nervous System 171 | 18,561
Urinary Tract 171 | 18,444
Blood and immune system 170 | 17,995
Digestive Tract 170 | 18,473
Liver and Pancreas 170 | 18,136
Respiratory system 170 | 17,484
Skin and soft tissues 170 | 18,115
Cardiovascular System 169 | 17,958

Target Family

Non-IDG 116 | 11,969
Enzyme 39 | 4,146
Epigenetic 9 | 242
Transcription Factor 5 | 1,400
Kinase 3 | 634
TF/Epigenetic 1 | 38

Compartment GO Term

Ribonucleoprotein granule 173 | 173
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L6 RPL6 Tbio Non-IDG -1.54952 37.8 65
Protein argonaute-4 AGO4 Tbio Non-IDG -1.38945 21.8 85
Sequestosome-1 SQSTM1 Tbio Non-IDG -2.71345 536.6 655
PAB-dependent poly(A)-specific ribonuclease subunit PAN2 PAN2 Tbio Enzyme -0.60206 3.89 74
Putative helicase MOV-10 MOV10 Tbio Enzyme -1.52177 33.8 100
Roquin-2 RC3H2 Tdark Non-IDG -0.70186 4.08 23
U6 snRNA-associated Sm-like protein LSm2 LSM2 Tbio Non-IDG -1.36424 21.5 96
ATP-dependent RNA helicase DDX25 DDX25 Tbio Enzyme -1.21748 20.9 45
Calcium-regulated heat-stable protein 1 CARHSP1 Tdark Transcription Factor -0.45954 3.34 41
DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G Tbio Non-IDG -2.77202 642.2 396