Development Level

Tbio 23 | 11,445
Tchem 4 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal craniofacial morpholo... 2 | 33
edema 2 | 59
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal motor capabilities-co... 1 | 5
abnormal neural tube closure 1 | 46
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
cleft palate 1 | 8
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
decreased total retina thickne... 1 | 17
enlarged heart 1 | 210
exencephaly 1 | 2
increased blood urea nitrogen ... 1 | 48
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased neutrophil cell numb... 1 | 46
limb grasping 1 | 41
microphthalmia 1 | 26
pallor 1 | 34
premature death 1 | 5
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
spina bifida 1 | 2
syndactyly 1 | 23

Disease

ovarian cancer 26 | 8,520
Carcinoma 21 | 11,493
medulloblastoma, large-cell 14 | 6,241
osteosarcoma 14 | 7,950
psoriasis 13 | 6,694
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 9 | 4,679
group 3 medulloblastoma 9 | 4,104
tuberculosis 9 | 2,010
Breast cancer 8 | 3,578
Kidney cancer 8 | 2,613
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
Alzheimer's disease 7 | 658
pancreatic cancer 7 | 2,398
Down syndrome 6 | 499
Neurodegenerative disease 6 | 414
Waldenstrons macroglobulinemia 6 | 765
astrocytic glioma 6 | 2,597
oligodendroglioma 6 | 2,850
primary pancreatic ductal adenocarcinoma 6 | 1,109
Multiple myeloma 5 | 1,332
Rheumatoid arthritis 5 | 1,191
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Alzheimer Disease 4 | 83
Cancer 4 | 2,499
Parkinson's disease 4 | 392
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
interstitial cystitis 4 | 2,312
juvenile dermatomyositis 4 | 1,187
non-small cell lung cancer 4 | 2,890
Amyloidosis 3 | 67
Astrocytoma, Pilocytic 3 | 3,081
Dementia 3 | 175
Liver Cirrhosis, Experimental 3 | 769
Mental Depression 3 | 333
Parkinson Disease 3 | 64
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
acute quadriplegic myopathy 3 | 1,158
diabetes mellitus 3 | 1,728
lung adenocarcinoma 3 | 2,716
mucosa-associated lymphoid tissue lymphoma 3 | 484
pediatric high grade glioma 3 | 1,064
primitive neuroectodermal tumor 3 | 3,035
Autosomal dominant late onset Parkinson disease 2 | 7
Cardiovascular system disease 2 | 246
Chronic Lymphocytic Leukemia 2 | 262
Chronic obstructive pulmonary disease 2 | 184
Duchenne muscular dystrophy 2 | 601
Endometrial cancer 2 | 311
Legionnaires' disease 2 | 20
Lewy Body Disease 2 | 21
Liver cancer 2 | 604
Parkinsonian Disorders 2 | 56
Toxic encephalopathy 2 | 141
Type 2 diabetes mellitus 2 | 272
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
inclusion-cell disease 2 | 16
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Anxiety Disorders 1 | 38
Brain Diseases 1 | 24
Cerebral Hemorrhage 1 | 42
Chronic tic disorder 1 | 8
Congenital diaphragmatic hernia 1 | 67
Deglutition Disorders 1 | 132
Forgetful 1 | 40
Gilles de la Tourette syndrome 1 | 47
Intermittent migraine headaches 1 | 68
Lewy Bodies 1 | 4
Memory Loss 1 | 40
Memory impairment 1 | 40
Microphthalmia 1 | 76
Muscle Rigidity 1 | 49
Myoclonus 1 | 74
PARKINSON DISEASE, LATE-ONSET 1 | 20
Paget's disease of bone 1 | 36
Paralysed 1 | 42
Paralysis 1 | 9
Postural instability 1 | 19
Primary ciliary dyskinesia 1 | 76
axial spondyloarthropathy 1 | 28

Tissue

Blood and immune system 31 | 16,909
Cardiovascular System 31 | 15,192
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678

Target Family

Non-IDG 29 | 12,091
Enzyme 2 | 4,145

Compartment GO Term

Retromer complex 31 | 31
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
VPS10 domain-containing receptor SorCS1 SORCS1 Tbio Non-IDG -1.36030 24.0 81
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12548 14.6 65
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248
Sorting nexin-6 SNX6 Tbio Non-IDG -1.02156 10.9 235
Ankyrin repeat domain-containing protein 50 ANKRD50 Tdark Non-IDG 0.23 0.78 55
DnaJ homolog subfamily C member 13 DNAJC13 Tbio Non-IDG -1.12451 16.4 28
Transmembrane protein 230 TMEM230 Tbio Non-IDG -1.27510 18.6 110
TBC1 domain family member 5 TBC1D5 Tbio Non-IDG -0.59459 3.64 31
Coiled-coil domain-containing protein 93 CCDC93 Tdark Non-IDG -0.25890 1.05 156