Development Level

Tbio 22 | 11,178
Tchem 4 | 1,885
Tdark 4 | 6,569

IMPC Phenotype

abnormal craniofacial morpholo... 2 | 33
edema 2 | 59
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal motor capabilities-co... 1 | 5
abnormal neural tube closure 1 | 46
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
cleft palate 1 | 8
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
decreased total retina thickne... 1 | 17
enlarged heart 1 | 210
exencephaly 1 | 2
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased neutrophil cell numb... 1 | 46
limb grasping 1 | 41
microphthalmia 1 | 26
pallor 1 | 34
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
spina bifida 1 | 2
syndactyly 1 | 23

Disease

ovarian cancer 25 | 8,297
Carcinoma 20 | 11,192
medulloblastoma, large-cell 13 | 6,086
osteosarcoma 13 | 7,766
psoriasis 12 | 6,514
atypical teratoid / rhabdoid tumor 10 | 4,971
tuberculosis 9 | 1,963
Kidney cancer 8 | 2,548
ependymoma 8 | 4,559
glioblastoma 8 | 5,635
group 3 medulloblastoma 8 | 4,002
lung cancer 8 | 4,607
Breast cancer 7 | 3,469
pancreatic cancer 7 | 2,322
Alzheimer's disease 6 | 640
Waldenstrons macroglobulinemia 6 | 742
primary pancreatic ductal adenocarcinoma 6 | 1,071
Down syndrome 5 | 480
Multiple myeloma 5 | 1,296
Neurodegenerative disease 5 | 402
astrocytic glioma 5 | 2,530
group 4 medulloblastoma 5 | 1,806
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,204
invasive ductal carcinoma 5 | 2,867
malignant mesothelioma 5 | 3,135
oligodendroglioma 5 | 2,768
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,911
Rheumatoid arthritis 4 | 1,156
adult high grade glioma 4 | 3,701
breast carcinoma 4 | 1,589
cystic fibrosis 4 | 1,629
interstitial cystitis 4 | 2,237
lung carcinoma 4 | 2,755
non-small cell lung cancer 4 | 2,799
Alzheimer Disease 3 | 80
Astrocytoma, Pilocytic 3 | 3,006
Cancer 3 | 2,388
Parkinson Disease 3 | 64
Parkinson's disease 3 | 378
acute quadriplegic myopathy 3 | 1,133
dermatomyositis 3 | 941
diabetes mellitus 3 | 1,683
juvenile dermatomyositis 3 | 1,147
lung adenocarcinoma 3 | 2,627
mucosa-associated lymphoid tissue lymphoma 3 | 473
pediatric high grade glioma 3 | 1,035
primitive neuroectodermal tumor 3 | 2,957
Amyloidosis 2 | 64
Autosomal dominant late onset Parkinson disease 2 | 7
Cardiovascular system disease 2 | 240
Chronic Lymphocytic Leukemia 2 | 254
Dementia 2 | 172
Duchenne muscular dystrophy 2 | 587
Endometrial cancer 2 | 301
Legionnaires' disease 2 | 20
Lewy Body Disease 2 | 21
Liver Cirrhosis, Experimental 2 | 733
Liver cancer 2 | 589
Mental Depression 2 | 325
Pick disease 2 | 1,856
Schizophrenia 2 | 1,136
Type 2 diabetes mellitus 2 | 268
acute myeloid leukemia 2 | 760
astrocytoma 2 | 1,113
colon cancer 2 | 1,428
ductal carcinoma in situ 2 | 1,686
gastric carcinoma 2 | 781
inclusion-cell disease 2 | 16
pancreatic carcinoma 2 | 555
pituitary cancer 2 | 1,915
primary Sjogren syndrome 2 | 710
subependymal giant cell astrocytoma 2 | 2,230
ulcerative colitis 2 | 1,765
Absent reflex 1 | 90
Absent tendon reflex 1 | 90
Bradykinesia 1 | 34
Chagas disease 1 | 38
Congenital pes cavus 1 | 86
Decreased number of large and small myelinated fibers 1 | 20
Decreased tendon reflex 1 | 121
Distal limb muscle weakness due to peripheral neuropathy 1 | 60
Distal muscle weakness 1 | 60
Frontotemporal dementia 1 | 51
Gaucher disease type 1 1 | 177
Holoprosencephaly 1 | 52
Liver neoplasms 1 | 126
Microcephaly 1 | 166
Neuropathy 1 | 254
Osteoporosis 1 | 348
Proteinuria 1 | 143
Reflex, Deep Tendon, Absent 1 | 90
Situs Inversus 1 | 61
Slow progression 1 | 88
Toxic encephalopathy 1 | 139
Tremor 1 | 112
hereditary spastic paraplegia 1 | 313
posterior fossa group A ependymoma 1 | 456
tuberculosis and treatment for 6 months 1 | 399

Tissue

Blood and immune system 30 | 16,909
Cardiovascular System 30 | 15,192
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678

Target Family

Non-IDG 28 | 12,091
Enzyme 2 | 4,145

Compartment GO Term

Retromer complex 30 | 30
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sortilin SORT1 Tchem Non-IDG -2.36389 235.8 137
Beta-secretase 1 BACE1 Tchem Enzyme -3.37358 2003.3 647
Protein wntless homolog WLS Tbio Non-IDG -2.50699 316.3 71
Sorting nexin-2 SNX2 Tbio Non-IDG -1.24500 17.2 141
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12548 14.6 65
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248
Ankyrin repeat domain-containing protein 50 ANKRD50 Tdark Non-IDG 0.23 0.78 55
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
VPS10 domain-containing receptor SorCS1 SORCS1 Tbio Non-IDG -1.36030 24.0 81
Sorting nexin-6 SNX6 Tbio Non-IDG -1.02156 10.9 235