Development Level

Tbio 37 | 11,445
Tdark 9 | 6,588
Tclin 5 | 613
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to o... 5 | 239
abnormal embryo size 4 | 220
embryonic lethality prior to t... 4 | 278
pallor 4 | 34
abnormal placenta size 2 | 20
abnormal skin coloration 2 | 25
decreased vertical activity 2 | 208
prenatal lethality prior to he... 2 | 87
abnormal digit morphology 1 | 10
abnormal embryonic autopod pla... 1 | 2
abnormal hindbrain development 1 | 16
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 5
abnormal stomach morphology 1 | 10
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
embryonic growth retardation 1 | 106
enlarged heart atrium 1 | 4
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
pale liver 1 | 6
prenatal lethality 1 | 28
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

ovarian cancer 23 | 8,520
osteosarcoma 22 | 7,950
Carcinoma 20 | 11,493
psoriasis 19 | 6,694
cytochrome-c oxidase deficiency disease 16 | 19
Leigh disease 15 | 100
diabetes mellitus 15 | 1,728
Acidosis, Lactic 14 | 97
Lactic acidemia 14 | 95
lung cancer 14 | 4,740
Cerebellar Ataxia 13 | 304
Cytochrome-c Oxidase Deficiency 13 | 17
Increased serum lactate 13 | 60
medulloblastoma, large-cell 13 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Autosomal recessive predisposition 11 | 1,442
Blepharoptosis 11 | 231
Multiple myeloma 11 | 1,332
astrocytic glioma 11 | 2,597
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
Obesity 10 | 678
Optic Atrophy 10 | 242
Sensorineural Hearing Loss (disorder) 10 | 284
ependymoma 10 | 4,679
glioblastoma 10 | 5,792
Dementia 9 | 175
Lactic acidosis 9 | 51
Myopathy 9 | 185
atypical teratoid / rhabdoid tumor 9 | 5,112
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Epilepsy 8 | 792
Heart failure 8 | 162
Muscle hypotonia 8 | 571
Ophthalmoplegia 8 | 106
group 3 medulloblastoma 8 | 4,104
oligodendroglioma 8 | 2,850
Breast cancer 7 | 3,578
CSF lactate increased 7 | 33
Dystonia 7 | 164
Dystonic disease 7 | 106
Failure to gain weight 7 | 365
Mitochondrial Myopathies 7 | 21
Neuropathy 7 | 261
Pediatric failure to thrive 7 | 365
Pick disease 7 | 1,894
Ragged-red fibers 7 | 21
Seizures 7 | 596
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
Anemia 6 | 365
Blindness, Cortical 6 | 24
Brain Ischemia 6 | 110
Cancer 6 | 2,499
Cortical visual impairment 6 | 24
Depressive disorder 6 | 409
Encephalopathies 6 | 43
Highly variable severity 6 | 157
Hypertrophic Cardiomyopathy 6 | 117
Intermittent migraine headaches 6 | 68
Leigh syndrome 6 | 28
Migraine Disorders 6 | 76
Nystagmus 6 | 317
Retinitis Pigmentosa 6 | 226
Schizophrenia 6 | 1,160
Tonic - clonic seizures 6 | 44
Variable expressivity 6 | 157
adult high grade glioma 6 | 3,801
non-small cell lung cancer 6 | 2,890
Abdominal Pain 5 | 98
Cardiomyopathy 5 | 116
Congenital Bilateral Cataracts 5 | 50
Congenital cataract 5 | 50
Congestive heart failure 5 | 113
Creatine phosphokinase serum increased 5 | 110
Developmental regression 5 | 95
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Elevated creatine kinase 5 | 110
Fatigue 5 | 182
Gliosis 5 | 56
Impaired exercise tolerance 5 | 42
Infantile onset 5 | 238
Kidney disease 5 | 430
Loss of developmental milestones 5 | 95
Mental deterioration in childhood 5 | 95
Mood swings 5 | 77
Neurodegenerative disease 5 | 414
Neurodevelopmental regression 5 | 95
Progressive disorder 5 | 142
Psychomotor regression 5 | 95
Psychomotor regression beginning in infancy 5 | 95
Psychomotor regression in infants 5 | 95
Psychomotor regression, progressive 5 | 95
Strabismus 5 | 270
Waldenstrons macroglobulinemia 5 | 765
Wolff-Parkinson-White syndrome 5 | 19
astrocytoma 5 | 1,146
colon cancer 5 | 1,478

Tissue

Endocrine System 53 | 18,159
Blood and immune system 52 | 16,909
Digestive Tract 52 | 17,369
Female tissues 52 | 17,400
Male tissues 52 | 17,142
Skin and soft tissues 52 | 17,230
Urinary Tract 52 | 16,678
Liver and Pancreas 51 | 16,750
Nervous System 51 | 16,725
Cardiovascular System 50 | 15,192
Respiratory system 49 | 16,393

Target Family

Enzyme 36 | 4,145
Non-IDG 14 | 12,091
Transporter 3 | 473
Transcription Factor 2 | 1,400

Compartment GO Term

Respiratory chain complex IV 55 | 55
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome c oxidase assembly protein COX11, mitochondrial COX11 Tbio Enzyme -1.42359 24.4 86
Cytochrome c oxidase assembly factor 5 COA5 Tdark Enzyme -0.77512 6.90 3
Cytochrome c oxidase assembly protein COX15 homolog COX15 Tbio Enzyme -1.37513 23.0 104
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80
Protoheme IX farnesyltransferase, mitochondrial COX10 Tbio Enzyme -1.60266 40.9 154
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.07841 114.8 103
Cytochrome b MT-CYB Tbio Non-IDG -3.77047 5856.5 134
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.23035 1641.3 479
Cytochrome c oxidase subunit 7C, mitochondrial COX7C Tdark Enzyme -1.02783 10.1 39
Protein SCO2 homolog, mitochondrial SCO2 Tbio Non-IDG -2.19082 152.8 117