Development Level

Tbio 15 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 4 | 239
abnormal embryo size 2 | 220
embryonic lethality prior to t... 2 | 278
increased circulating alkaline... 2 | 122
abnormal behavior 1 | 298
abnormal digit morphology 1 | 10
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased lean body mass 1 | 135
embryonic growth retardation 1 | 106
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased circulating sodium l... 1 | 71
pallor 1 | 34
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 10 | 8,520
Paraganglioma 8 | 15
Von Hippel-Lindau disease 8 | 19
osteosarcoma 8 | 7,950
psoriasis 8 | 6,694
Neurofibromatosis 7 | 40
Persistent generalized lymphadenopathy 7 | 15
Phaeochromocytoma 7 | 20
Carcinoma 6 | 11,493
Cerebellar Ataxia 6 | 304
glioblastoma 6 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Cancer 5 | 2,499
Chondroma 5 | 15
Cognitive delay 5 | 608
Deglutition Disorders 5 | 132
Gastrointestinal Hemorrhage 5 | 52
Gastrointestinal Stromal Tumors 5 | 48
Gastrointestinal stromal tumor 5 | 62
Global developmental delay 5 | 608
Heart failure 5 | 162
Intestinal Obstruction 5 | 31
Mental and motor retardation 5 | 608
Mitochondrial complex II deficiency 5 | 5
Optic Atrophy 5 | 242
atypical teratoid / rhabdoid tumor 5 | 5,112
diabetes mellitus 5 | 1,728
lung cancer 5 | 4,740
medulloblastoma, large-cell 5 | 6,241
Adult onset 4 | 82
Autosomal recessive predisposition 4 | 1,442
Carotid Body Paraganglioma 4 | 4
Congestive heart failure 4 | 113
Constipation 4 | 181
Dull intelligence 4 | 645
Dyschezia 4 | 135
Fatigue 4 | 182
Glomus Jugulare Tumor 4 | 4
Impaired cognition 4 | 96
Increased gastric cancer 4 | 21
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Mental impairment 4 | 95
Nausea and vomiting 4 | 97
Obesity 4 | 678
Pheochromocytoma 4 | 24
Poor school performance 4 | 645
Sarcoma 4 | 62
Stomach Neoplasms 4 | 300
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
extra-adrenal pheochromocytoma 4 | 7
Abdominal Pain 3 | 98
Acidosis, Lactic 3 | 97
Aphonia 3 | 3
Babinski Reflex 3 | 100
Big calvaria 3 | 147
Cardiomyopathy 3 | 116
Congenital Bilateral Cataracts 3 | 50
Congenital cataract 3 | 50
Congenital deafness 3 | 185
Deafness 3 | 198
Dystonia 3 | 164
Dystonic disease 3 | 106
Elevated heart rate 3 | 25
Gastrointestinal Neoplasms 3 | 7
Goiter 3 | 38
Hearing Loss, Partial 3 | 185
Hemangioma, Cavernous 3 | 20
Hyperhidrosis disorder 3 | 81
Hyperpigmentation 3 | 37
Hypertrophic Cardiomyopathy 3 | 117
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Increased sweating 3 | 81
Isolated cases 3 | 72
Lactic acidemia 3 | 95
Lipoma 3 | 32
Low Vision 3 | 174
Macroglossia 3 | 65
Melanocytic nevus 3 | 43
Meningioma 3 | 41
Muscle Weakness 3 | 170
Noncancerous mole 3 | 28
Ophthalmoplegia 3 | 106
Palmoplantar keratosis 3 | 74
Palpitations 3 | 18
Papilloma 3 | 44
Renal Cell Carcinoma 3 | 214
Sebaceous adenoma 3 | 26
Sweating 3 | 81
Tachycardia 3 | 43
Tinnitus 3 | 19
Urticaria 3 | 67
Visual Impairment 3 | 174
Weight decreased 3 | 103
hearing impairment 3 | 199

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Enzyme 12 | 4,145
Non-IDG 4 | 12,091
Kinase 1 | 634

Compartment GO Term

Respiratory chain complex II 17 | 17
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Succinate dehydrogenase assembly factor 2, mitochondrial SDHAF2 Tbio Enzyme -1.86465 69.5 34
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial SDHC Tbio Enzyme -2.73791 419.9 129
Cytochrome b MT-CYB Tbio Non-IDG -3.77047 5856.5 134
Transmembrane protein 127 TMEM127 Tbio Non-IDG -1.31365 19.5 26
Frataxin, mitochondrial FXN Tbio Non-IDG -3.02739 1114.8 403
Citrate synthase, mitochondrial CS Tbio Enzyme -2.61735 325.4 239
Succinate dehydrogenase assembly factor 4, mitochondrial SDHAF4 Tbio Enzyme -0.44083 2.28 33
6-phosphogluconolactonase PGLS Tbio Enzyme -2.29363 182.3 148
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 Tbio Enzyme -2.34320 203.3 504
Succinate dehydrogenase assembly factor 1, mitochondrial SDHAF1 Tbio Enzyme -0.69440 4.59 110