Development Level

Tbio 56 | 10,625
Tclin 49 | 602
Tdark 13 | 7,003
Tchem 10 | 1,890

IMPC Term

preweaning lethality, complete... 17 | 633
embryonic lethality prior to o... 7 | 148
embryonic lethality prior to t... 5 | 187
abnormal embryo size 4 | 112
embryonic growth retardation 3 | 28
pallor 3 | 13
abnormal behavior 2 | 226
abnormal lens morphology 2 | 73
abnormal skin coloration 2 | 18
decreased bone mineral content 2 | 157
increased exploration in new e... 2 | 56
increased startle reflex 2 | 38
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal embryo turning 1 | 15
abnormal foot plate morphology 1 | 2
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal liver size 1 | 4
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 4
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal skin appearance 1 | 8
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
abnormal visceral yolk sac mor... 1 | 2
decreased blood urea nitrogen ... 1 | 31
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased lactate dehydrogenas... 1 | 14
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
enlarged heart atrium 1 | 2
hyperactivity 1 | 108
hypoactivity 1 | 89
increased CD4-positive, CD25-p... 1 | 18
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased bone mineral content 1 | 92
increased circulating free fat... 1 | 17
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
pale liver 1 | 5
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
vertebral fusion 1 | 23

Disease

ovarian cancer 66 | 8,484
Diabetes mellitus type 2 48 | 69
Treatment Refractory Type 2 Diabetes Mellitus 48 | 53
Multiple myeloma 42 | 1,327
osteosarcoma 42 | 7,933
Leigh disease 41 | 81
psoriasis 35 | 6,685
lung cancer 32 | 4,466
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,795
MITOCHONDRIAL COMPLEX I DEFICIENCY 25 | 37
glioblastoma 23 | 5,572
medulloblastoma, large-cell 23 | 6,234
diabetes mellitus 20 | 1,663
atypical teratoid / rhabdoid tumor 19 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,289
astrocytic glioma 18 | 2,241
ependymoma 17 | 2,514
Cancer 15 | 2,346
NADH:Q(1) Oxidoreductase deficiency 15 | 20
astrocytoma 15 | 1,493
Waldenstrons macroglobulinemia 14 | 765
Obesity 13 | 616
Leber hereditary optic neuropathy 12 | 17
LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY 11 | 14
Lactic acidosis 11 | 42
Parkinson's disease 11 | 364
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
lung adenocarcinoma 11 | 2,713
malignant mesothelioma 11 | 3,162
oligodendroglioma 11 | 2,849
ulcerative colitis 11 | 2,087
Breast cancer 10 | 3,094
Mitochondrial myopathy 10 | 23
Neurodegenerative disease 10 | 383
Optic Atrophy, Hereditary, Leber 10 | 14
Pick disease 10 | 1,893
cytochrome-c oxidase deficiency disease 10 | 14
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
tuberculosis 10 | 1,557
Cytochrome-c Oxidase Deficiency 9 | 15
Kidney disease 9 | 396
Neuropathy 9 | 210
invasive ductal carcinoma 9 | 2,950
medulloblastoma 9 | 1,524
non-small cell lung cancer 9 | 2,798
Alzheimer's disease 8 | 644
non primary Sjogren syndrome sicca 8 | 840
posterior fossa group B ependymoma 8 | 1,530
Anemia 7 | 252
Cerebrovascular disease 7 | 231
Diabetes Mellitus, Experimental 7 | 106
Heart disease 7 | 279
Hyperglycemia 7 | 120
acute myeloid leukemia 7 | 780
breast carcinoma 7 | 1,614
pediatric high grade glioma 7 | 2,712
primitive neuroectodermal tumor 7 | 3,031
subependymal giant cell astrocytoma 7 | 2,287
Cardiomyopathies 6 | 90
Hypertension 6 | 287
MELAS syndrome 6 | 17
Neoplastic Syndromes, Hereditary 6 | 48
Rheumatoid Arthritis 6 | 1,160
aldosterone-producing adenoma 6 | 664
group 4 medulloblastoma 6 | 1,875
pancreatic cancer 6 | 2,300
pituitary cancer 6 | 1,972
Atherosclerosis 5 | 275
Brain Ischemia 5 | 87
COENZYME Q10 DEFICIENCY, PRIMARY, 1 5 | 6
Cardiomyopathy 5 | 110
Cerebellar Ataxia 5 | 72
Degenerative polyarthritis 5 | 93
Diabetes Mellitus, Non-Insulin-Dependent 5 | 157
Hypertrophic Cardiomyopathy 5 | 56
Liver disease 5 | 219
Malaria 5 | 140
Mitochondrial Encephalomyopathies 5 | 11
Mitochondrial complex II deficiency 5 | 5
Multiple acyl-CoA dehydrogenase deficiency 5 | 26
Paraganglioma 5 | 12
Persistent generalized lymphadenopathy 5 | 15
Phaeochromocytoma 5 | 20
Pneumonia 5 | 133
Polycystic Ovary Syndrome 5 | 332
Schizophrenia 5 | 501
adrenocortical carcinoma 5 | 1,427
adult high grade glioma 5 | 2,148
ductal carcinoma in situ 5 | 1,745
gastric carcinoma 5 | 832
lung carcinoma 5 | 2,844
Arthritis 4 | 248
Coronary artery disease 4 | 240
Duchenne muscular dystrophy 4 | 602
Hypertensive disease 4 | 193
Inflammatory bowel disease 4 | 142
acute quadriplegic myopathy 4 | 1,157
juvenile dermatomyositis 4 | 1,189
pilocytic astrocytoma 4 | 3,086
tuberculosis and treatment for 6 months 4 | 686

Tissue

Cardiovascular System 126 | 17,958
Endocrine System 126 | 18,512
Female tissues 126 | 18,647
Liver and Pancreas 126 | 18,136
Nervous System 126 | 18,561
Urinary Tract 126 | 18,444
Blood and immune system 125 | 17,995
Digestive Tract 125 | 18,473
Male tissues 125 | 17,969
Respiratory system 125 | 17,484
Skin and soft tissues 125 | 18,115

Target Family

Enzyme 93 | 4,146
Non-IDG 28 | 11,971
Kinase 2 | 634
Transcription Factor 2 | 1,400
Transporter 2 | 473
Nuclear Receptor 1 | 48

Compartment GO Term

Respiratory chain 128 | 128
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NADH-ubiquinone oxidoreductase chain 6 MT-ND6 Tclin Enzyme -2.74395 585.6 62
Cytochrome c oxidase subunit 6A1, mitochondrial COX6A1 Tbio Enzyme -1.00384 11.8 165
Protein SCO2 homolog, mitochondrial SCO2 Tbio Non-IDG -2.16453 144.3 98
Cytochrome c oxidase subunit 7C, mitochondrial COX7C Tdark Enzyme -0.99133 9.67 34
Cytochrome b MT-CYB Tbio Non-IDG -3.74473 5676.0 122
Ubiquinone biosynthesis protein COQ9, mitochondrial COQ9 Tbio Non-IDG -1.98869 99.9 68
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 Tclin Enzyme -2.85403 720.1 90
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 Tclin Enzyme -2.13591 109.9 147
Cytochrome c oxidase subunit 7A1, mitochondrial COX7A1 Tbio Enzyme -1.28295 20.3 59
Cytochrome c oxidase subunit 7B, mitochondrial COX7B Tbio Enzyme -0.60140 3.69 49