Development Level

Tbio 36 | 10,625
Tchem 10 | 1,890
Tclin 6 | 602
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 7 | 633
embryonic lethality prior to o... 4 | 148
increased circulating sodium l... 3 | 71
embryonic lethality prior to t... 2 | 187
abnormal blood vessel morpholo... 1 | 2
abnormal heart morphology 1 | 51
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
decreased circulating alanine ... 1 | 53
decreased circulating glucose ... 1 | 121
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
enlarged heart 1 | 111
increased circulating alkaline... 1 | 119
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
small testis 1 | 37

Disease

ovarian cancer 32 | 8,492
medulloblastoma, large-cell 29 | 6,234
malignant mesothelioma 28 | 3,163
psoriasis 27 | 6,685
lung cancer 26 | 4,473
Cancer 24 | 2,346
group 3 medulloblastoma 24 | 2,254
osteosarcoma 24 | 7,933
primitive neuroectodermal tumor 23 | 3,031
Breast cancer 22 | 3,099
glioblastoma 22 | 5,572
non-small cell lung cancer 22 | 2,798
pediatric high grade glioma 21 | 2,712
atypical teratoid / rhabdoid tumor 20 | 4,369
colon cancer 16 | 1,475
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
adrenocortical carcinoma 12 | 1,427
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
invasive ductal carcinoma 12 | 2,950
lung adenocarcinoma 12 | 2,714
Carcinoma 11 | 2,147
ductal carcinoma in situ 11 | 1,745
nasopharyngeal carcinoma 11 | 1,056
posterior fossa group A ependymoma 10 | 1,511
Nijmegen breakage syndrome 9 | 23
diabetes mellitus 9 | 1,663
ulcerative colitis 9 | 2,087
Mammary Neoplasms 8 | 410
Werner syndrome 8 | 29
oligodendroglioma 8 | 2,849
Bloom syndrome 7 | 30
Colorectal Neoplasms 7 | 217
IGA Glomerulonephritis 7 | 454
Waldenstrons macroglobulinemia 7 | 765
sonic hedgehog group medulloblastoma 7 | 1,482
tuberculosis 7 | 1,563
Ataxia telangiectasia 6 | 32
Cockayne syndrome 6 | 54
Endometriosis 6 | 535
Seckel syndrome 6 | 35
pilocytic astrocytoma 6 | 3,086
Atopic dermatitis 5 | 944
Fanconi's anemia 5 | 50
Xeroderma pigmentosum 5 | 41
astrocytoma 5 | 1,493
breast carcinoma 5 | 1,614
cystic fibrosis 5 | 1,670
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
lung carcinoma 5 | 2,844
Kidney disease 4 | 397
Lung Neoplasms 4 | 171
Lynch syndrome 4 | 35
Malignant tumor of ovary 4 | 25
Peripheral Neuropathy 4 | 303
Prostatic Neoplasms 4 | 471
Rothmund-Thomson syndrome 4 | 22
Stomach Neoplasms 4 | 282
Vaccinia 4 | 37
acute quadriplegic myopathy 4 | 1,157
astrocytic glioma 4 | 2,241
atypical teratoid/rhabdoid tumor 4 | 1,095
hepatocellular carcinoma 4 | 550
juvenile dermatomyositis 4 | 1,189
pancreatic cancer 4 | 2,300
primary Sjogren syndrome 4 | 789
Acquired immunodeficiency syndrome 3 | 164
Acute lymphoid leukemia 3 | 25
Acute myeloid leukemia, disease 3 | 16
Acute promyelocytic leukemia, FAB M3 3 | 10
Adenocarcinoma of pancreas 3 | 12
Anemia 3 | 252
Bladder Neoplasm 3 | 109
Breast Cancer, Familial 3 | 12
Colonic Neoplasms 3 | 126
Familial adenomatous polyposis 3 | 33
Hereditary Breast and Ovarian Cancer Syndrome 3 | 14
Intellectual disability 3 | 573
Kidney cancer 3 | 121
Lymphomatous meningitis 3 | 3
Melanoma 3 | 261
Meningeal Leukemia 3 | 7
Metastatic Breast Carcinoma 3 | 21
Multiple Sclerosis 3 | 498
Neoplastic Syndromes, Hereditary 3 | 48
Neurodegenerative disease 3 | 383
Pancreatic Neoplasm 3 | 79
Rheumatoid Arthritis 3 | 1,171
adult high grade glioma 3 | 2,148
chronic lymphocytic leukemia 3 | 244
cutaneous lupus erythematosus 3 | 1,056
dermatomyositis 3 | 967
glioblastoma multiforme 3 | 347
group 4 medulloblastoma 3 | 1,875
non primary Sjogren syndrome sicca 3 | 840
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 1,530
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis and treatment for 6 months 3 | 686
Brain Ischemia 2 | 87
active Crohn's disease 2 | 918

Tissue

Blood and immune system 54 | 17,995
Cardiovascular System 54 | 17,958
Digestive Tract 54 | 18,473
Endocrine System 54 | 18,512
Female tissues 54 | 18,647
Liver and Pancreas 54 | 18,136
Male tissues 54 | 17,969
Nervous System 54 | 18,561
Respiratory system 54 | 17,484
Skin and soft tissues 54 | 18,115
Urinary Tract 54 | 18,444

Target Family

Non-IDG 29 | 11,969
Enzyme 18 | 4,146
Kinase 4 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408

Compartment GO Term

Replisome 54 | 54
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.02098 96.6 198
Cell cycle checkpoint control protein RAD9A RAD9A Tbio Non-IDG -2.13819 136.3 864
Replication protein A 70 kDa DNA-binding subunit RPA1 Tchem Non-IDG -2.46324 281.9 299
Flap endonuclease 1 FEN1 Tchem Enzyme -2.77484 533.8 332
ATR-interacting protein ATRIP Tbio Non-IDG -1.59835 40.9 328
Transcriptional activator protein Pur-beta PURB Tbio Non-IDG -1.46736 31.8 76
DNA polymerase delta subunit 4 POLD4 Tbio Enzyme -0.84887 7.32 16
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.77275 513.9 350
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.71557 51004.8 5255
Exonuclease 1 EXO1 Tbio Enzyme -2.61142 403.9 226