Development Level

Tbio 92 | 10,625
Tchem 17 | 1,890
Tclin 7 | 602
Tdark 6 | 7,003

IMPC Term

preweaning lethality, complete... 14 | 633
embryonic lethality prior to o... 6 | 148
embryonic lethality prior to t... 4 | 187
preweaning lethality, incomple... 4 | 260
increased circulating sodium l... 3 | 71
abnormal behavior 2 | 226
decreased body weight 2 | 174
enlarged heart 2 | 111
increased bone mineral density 2 | 52
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal blood vessel morpholo... 1 | 2
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal gait 1 | 51
abnormal hair texture 1 | 4
abnormal heart morphology 1 | 51
abnormal pharyngeal arch morph... 1 | 2
abnormal placement of pupils 1 | 4
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
absent pinna reflex 1 | 21
anophthalmia 1 | 20
cardiovascular system phenotyp... 1 | 35
corneal opacity 1 | 25
decreased circulating alanine ... 1 | 53
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased exploration in new e... 1 | 9
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
decreased lumbar vertebrae num... 1 | 62
decreased total body fat amoun... 1 | 186
embryonic growth retardation 1 | 28
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased thoracic vertebrae n... 1 | 8
limb grasping 1 | 35
male infertility 1 | 62
narrow eye opening 1 | 15
polydactyly 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
small testis 1 | 37
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

ovarian cancer 76 | 8,484
medulloblastoma, large-cell 66 | 6,234
osteosarcoma 64 | 7,933
glioblastoma 53 | 5,572
malignant mesothelioma 53 | 3,162
lung cancer 52 | 4,466
psoriasis 52 | 6,685
Cancer 51 | 2,346
group 3 medulloblastoma 51 | 2,254
primitive neuroectodermal tumor 50 | 3,031
Breast cancer 46 | 3,094
non-small cell lung cancer 46 | 2,798
atypical teratoid / rhabdoid tumor 40 | 4,369
pediatric high grade glioma 38 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
lung adenocarcinoma 33 | 2,713
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,988
adrenocortical carcinoma 30 | 1,427
Carcinoma 28 | 2,147
colon cancer 28 | 1,475
invasive ductal carcinoma 27 | 2,950
nasopharyngeal carcinoma 27 | 1,056
ductal carcinoma in situ 26 | 1,745
Fanconi's anemia 24 | 50
Bloom syndrome 22 | 30
posterior fossa group A ependymoma 20 | 1,511
sonic hedgehog group medulloblastoma 20 | 1,482
oligodendroglioma 16 | 2,849
Endometriosis 15 | 535
Mammary Neoplasms 15 | 410
astrocytic glioma 14 | 2,241
diabetes mellitus 14 | 1,663
ulcerative colitis 13 | 2,087
Atopic dermatitis 12 | 944
Nijmegen breakage syndrome 12 | 23
Peripheral Neuropathy 12 | 303
atypical teratoid/rhabdoid tumor 12 | 1,095
breast carcinoma 12 | 1,614
Anemia 11 | 252
Waldenstrons macroglobulinemia 11 | 765
Werner syndrome 11 | 29
Xeroderma pigmentosum 11 | 41
adult high grade glioma 11 | 2,148
lung carcinoma 11 | 2,844
pilocytic astrocytoma 11 | 3,086
Ataxia telangiectasia 10 | 31
Cockayne syndrome 10 | 54
IGA Glomerulonephritis 10 | 454
Seckel syndrome 10 | 34
ependymoma 10 | 2,514
non primary Sjogren syndrome sicca 10 | 840
Neoplastic Syndromes, Hereditary 9 | 48
astrocytoma 9 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
pancreatic cancer 9 | 2,300
pituitary cancer 9 | 1,972
tuberculosis 9 | 1,557
Fanconi Anemia 8 | 19
Hereditary Breast and Ovarian Cancer Syndrome 8 | 14
Pick disease 8 | 1,893
Rheumatoid Arthritis 8 | 1,160
Rothmund-Thomson syndrome 8 | 22
acute myeloid leukemia 8 | 780
juvenile dermatomyositis 8 | 1,189
Colorectal Neoplasms 7 | 217
Stomach Neoplasms 7 | 282
acute quadriplegic myopathy 7 | 1,157
posterior fossa group B ependymoma 7 | 1,530
primary Sjogren syndrome 7 | 789
Breast Cancer, Familial 6 | 12
Lynch syndrome 6 | 33
Malignant neoplasm of breast 6 | 63
Pancreatic Neoplasm 6 | 79
Prostatic Neoplasms 6 | 471
dermatomyositis 6 | 933
medulloblastoma 6 | 1,524
Adenoid Cystic Carcinoma 5 | 99
Aplastic anemia 5 | 18
Chronic Lymphocytic Leukemia 5 | 242
Colonic Neoplasms 5 | 126
Intellectual disability 5 | 573
Li-Fraumeni Syndrome 5 | 13
Multiple myeloma 5 | 1,327
Photosensitive trichothiodystrophy 5 | 24
Prostate cancer 5 | 172
glioblastoma multiforme 5 | 347
group 4 medulloblastoma 5 | 1,875
interstitial cystitis 5 | 2,299
ovarian neoplasm 5 | 97
pancreatic carcinoma 5 | 567
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
progressive supranuclear palsy 5 | 674
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis and treatment for 6 months 5 | 686
Malignant neoplasm of prostate 4 | 67
Polycystic Ovary Syndrome 4 | 332
cystic fibrosis 4 | 1,665
esophageal adenocarcinoma 4 | 737
hepatocellular carcinoma 4 | 532
inflammatory breast cancer 4 | 404

Tissue

Digestive Tract 122 | 18,473
Endocrine System 122 | 18,512
Liver and Pancreas 122 | 18,136
Nervous System 122 | 18,561
Blood and immune system 121 | 17,995
Cardiovascular System 121 | 17,958
Female tissues 121 | 18,647
Male tissues 121 | 17,969
Respiratory system 121 | 17,484
Urinary Tract 121 | 18,444
Skin and soft tissues 120 | 18,115

Target Family

Non-IDG 68 | 11,971
Enzyme 42 | 4,146
Kinase 6 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
GPCR 1 | 406

Compartment GO Term

Replication fork 122 | 122
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.10426 11.5 1277
Replication protein A 32 kDa subunit RPA2 Tbio Non-IDG -1.76828 59.7 468
Replication factor C subunit 3 RFC3 Tbio Non-IDG -1.28299 19.5 161
Replication factor C subunit 5 RFC5 Tbio Non-IDG -1.02728 11.1 64
Ubiquitin-conjugating enzyme E2 B UBE2B Tbio Non-IDG -1.56439 38.8 140
Replication factor C subunit 2 RFC2 Tbio Non-IDG -1.34287 19.7 194
Replication factor C subunit 1 RFC1 Tbio Non-IDG -1.40675 26.5 184
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.59332 3912.4 208
ATP-dependent DNA helicase Q1 RECQL Tbio Enzyme -1.84578 76.6 72
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.17963 1388.1 188