Development Level

Tbio 103 | 11,445
Tchem 14 | 1,598
Tclin 8 | 613
Tdark 7 | 6,588

IMPC Phenotype

preweaning lethality, complete... 18 | 979
embryonic lethality prior to o... 11 | 239
embryonic lethality prior to t... 9 | 278
preweaning lethality, incomple... 9 | 499
abnormal embryo size 5 | 220
abnormal behavior 3 | 298
abnormal heart morphology 3 | 162
embryonic growth retardation 3 | 106
enlarged heart 3 | 210
increased mean corpuscular vol... 3 | 92
abnormal blood vessel morpholo... 2 | 5
abnormal embryo turning 2 | 31
abnormal pharyngeal arch morph... 2 | 8
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased circulating sodium l... 2 | 71
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
prenatal lethality 2 | 28
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo development 1 | 7
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hair texture 1 | 4
abnormal hindbrain development 1 | 16
abnormal liver morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placement of pupils 1 | 6
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal somite shape 1 | 5
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
absent pinna reflex 1 | 23
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 90 | 11,493
ovarian cancer 84 | 8,520
group 3 medulloblastoma 73 | 4,104
medulloblastoma, large-cell 68 | 6,241
osteosarcoma 67 | 7,950
glioblastoma 58 | 5,792
Cancer 57 | 2,499
lung cancer 56 | 4,740
malignant mesothelioma 56 | 3,232
psoriasis 54 | 6,694
Breast cancer 52 | 3,578
atypical teratoid / rhabdoid tumor 51 | 5,112
primitive neuroectodermal tumor 49 | 3,035
non-small cell lung cancer 47 | 2,890
adult high grade glioma 40 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
lung adenocarcinoma 36 | 2,716
Kidney cancer 33 | 2,613
ependymoma 32 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
adrenocortical carcinoma 29 | 1,428
Fanconi anemia 27 | 56
colon cancer 27 | 1,478
ductal carcinoma in situ 27 | 1,745
invasive ductal carcinoma 27 | 2,951
nasopharyngeal carcinoma 27 | 1,058
Bloom syndrome 24 | 29
Autosomal recessive predisposition 21 | 1,442
Xeroderma pigmentosum 19 | 43
Short stature 18 | 531
breast carcinoma 18 | 1,638
oligodendroglioma 18 | 2,850
Small head 17 | 374
Breast Neoplasms 16 | 445
Mammary Neoplasms 16 | 425
astrocytic glioma 16 | 2,597
diabetes mellitus 16 | 1,728
Astrocytoma, Pilocytic 15 | 3,081
Endometriosis 15 | 540
Cognitive delay 14 | 608
Dull intelligence 14 | 645
Global developmental delay 14 | 608
Intellectual disability 14 | 1,016
Low intelligence 14 | 645
Mental Retardation 14 | 645
Mental and motor retardation 14 | 608
Mental deficiency 14 | 645
Nijmegen breakage syndrome 14 | 24
Poor school performance 14 | 645
Werner syndrome 14 | 29
lung carcinoma 14 | 2,843
ulcerative colitis 14 | 1,819
Atopic dermatitis 13 | 952
Schizophrenia 13 | 1,160
Ataxia telangiectasia 12 | 34
Thrombocytopenia 12 | 197
Anemia 11 | 365
Chromosome Breakage 11 | 36
Pick disease 11 | 1,894
Waldenstrons macroglobulinemia 11 | 765
non primary Sjogren syndrome sicca 11 | 891
tuberculosis 11 | 2,010
Cockayne syndrome 10 | 60
Cryptorchidism 10 | 296
Seckel syndrome 10 | 34
Xeroderma pigmentosum group F 10 | 22
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
pancreatic cancer 10 | 2,398
pituitary cancer 10 | 1,972
Increased chromosomal breakage 9 | 27
Prostatic Neoplasms 9 | 495
Rothmund-Thomson syndrome 9 | 19
astrocytoma 9 | 1,146
pediatric high grade glioma 9 | 1,064
Acquired scoliosis 8 | 281
Colorectal Neoplasms 8 | 243
Curvature of spine 8 | 282
Decreased platelet count 8 | 111
Epilepsy 8 | 792
Esophageal atresia with or without tracheoesophageal fistula 8 | 21
Fetal Growth Retardation 8 | 189
Hereditary Breast and Ovarian Cancer Syndrome 8 | 14
Hypoplastic mandible condyle 8 | 275
Infant, Small for Gestational Age 8 | 176
Intrauterine retardation 8 | 176
Mandibular hypoplasia 8 | 275
Melanoma 8 | 711
Micrognathism 8 | 275
Seizures 8 | 596
Stomach Neoplasms 8 | 300
acute myeloid leukemia 8 | 783
acute quadriplegic myopathy 8 | 1,158
juvenile dermatomyositis 8 | 1,187
Leukopenia 7 | 72
Liver cancer 7 | 604
Pancreatic Neoplasm 7 | 85
Rheumatoid arthritis 7 | 1,191
Strabismus 7 | 270
hypopigmented skin patch 7 | 59
primary Sjogren syndrome 7 | 735

Tissue

Digestive Tract 130 | 17,369
Endocrine System 130 | 18,159
Female tissues 130 | 17,400
Liver and Pancreas 130 | 16,750
Male tissues 130 | 17,142
Nervous System 130 | 16,725
Respiratory system 130 | 16,393
Skin and soft tissues 130 | 17,230
Urinary Tract 130 | 16,678
Blood and immune system 129 | 16,909
Cardiovascular System 125 | 15,192

Target Family

Non-IDG 75 | 12,091
Enzyme 45 | 4,145
Kinase 6 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
GPCR 1 | 408

Compartment GO Term

Replication fork 132 | 132
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase SHPRH SHPRH Tbio Epigenetic -0.99196 10.7 137
Transcriptional activator protein Pur-beta PURB Tbio Non-IDG -1.49692 30.7 79
Ewing's tumor-associated antigen 1 ETAA1 Tbio Non-IDG -0.76616 7.50 40
DNA annealing helicase and endonuclease ZRANB3 ZRANB3 Tbio Enzyme -2.18014 154.3 36
ATP-dependent DNA helicase Q5 RECQL5 Tbio Enzyme -1.67373 56.2 148
DNA replication complex GINS protein SLD5 GINS4 Tbio Non-IDG -1.28555 18.6 59
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
DNA polymerase delta subunit 4 POLD4 Tbio Enzyme -0.84887 7.32 24
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125