Development Level

Tbio 104 | 10,625
Tdark 17 | 7,003
Tchem 9 | 1,890
Tclin 5 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 24
Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

preweaning lethality, complete... 7 | 633
decreased grip strength 4 | 123
decreased body length 3 | 108
decreased mean corpuscular hem... 3 | 34
increased B cell number 3 | 23
abnormal QRS complex 2 | 25
decreased granulocyte number 2 | 8
decreased lean body mass 2 | 195
decreased pre-pro B cell numbe... 2 | 2
decreased total body fat amoun... 2 | 186
hypoactivity 2 | 89
increased T cell number 2 | 15
increased mature B cell number 2 | 12
increased mean corpuscular hem... 2 | 93
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal eyelid aperture 1 | 3
abnormal maxilla morphology 1 | 16
abnormal pelvic girdle bone mo... 1 | 11
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
abnormal thoracic cage shape 1 | 3
decreased CD4-positive, CD25-p... 1 | 24
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased gamma-delta T cell n... 1 | 18
decreased late germinal center... 1 | 2
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased myeloid cell number ... 1 | 1
decreased pro-B cell number 1 | 2
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating chloride... 1 | 43
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased early germinal cente... 1 | 2
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased immature B cell numb... 1 | 1
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased plasma cell number 1 | 5
increased pre-B cell number 1 | 1
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased urine magnesium leve... 1 | 1
preweaning lethality, incomple... 1 | 260
shortened ST segment 1 | 9

Disease

ovarian cancer 86 | 8,491
osteosarcoma 65 | 7,933
medulloblastoma, large-cell 63 | 6,234
glioblastoma 56 | 5,572
psoriasis 49 | 6,685
atypical teratoid / rhabdoid tumor 40 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,289
lung cancer 38 | 4,473
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,988
pilocytic astrocytoma 28 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,956
invasive ductal carcinoma 27 | 2,950
malignant mesothelioma 26 | 3,163
non-small cell lung cancer 26 | 2,798
primitive neuroectodermal tumor 25 | 3,031
pancreatic cancer 24 | 2,300
Breast cancer 23 | 3,098
lung adenocarcinoma 23 | 2,714
oligodendroglioma 23 | 2,849
subependymal giant cell astrocytoma 23 | 2,287
Pick disease 22 | 1,893
pediatric high grade glioma 22 | 2,712
astrocytoma 21 | 1,493
adult high grade glioma 20 | 2,148
ulcerative colitis 20 | 2,087
ductal carcinoma in situ 19 | 1,745
ependymoma 19 | 2,514
astrocytic glioma 17 | 2,241
breast carcinoma 17 | 1,614
lung carcinoma 17 | 2,844
pituitary cancer 17 | 1,972
tuberculosis 17 | 1,563
Cancer 16 | 2,346
Carcinoma 16 | 2,147
Multiple myeloma 16 | 1,327
primary pancreatic ductal adenocarcinoma 16 | 1,271
sonic hedgehog group medulloblastoma 16 | 1,482
dermatomyositis 15 | 966
gastric carcinoma 15 | 832
group 4 medulloblastoma 15 | 1,875
Rheumatoid Arthritis 14 | 1,170
juvenile dermatomyositis 14 | 1,189
acute quadriplegic myopathy 13 | 1,157
atypical teratoid/rhabdoid tumor 13 | 1,095
colon cancer 13 | 1,475
group 3 medulloblastoma 13 | 2,254
interstitial cystitis 13 | 2,299
medulloblastoma 13 | 1,524
posterior fossa group A ependymoma 13 | 1,511
cystic fibrosis 12 | 1,670
esophageal adenocarcinoma 12 | 737
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
posterior fossa group B ependymoma 11 | 1,530
Neurodegenerative disease 10 | 383
Alzheimer's disease 9 | 644
Waldenstrons macroglobulinemia 9 | 764
fibroadenoma 9 | 557
spina bifida 9 | 1,064
Obesity 8 | 616
cutaneous lupus erythematosus 8 | 1,056
Amyotrophic Lateral Sclerosis 7 | 432
Duchenne muscular dystrophy 7 | 602
Intellectual disability 7 | 573
Parkinson's disease 7 | 364
active Crohn's disease 7 | 918
acute myeloid leukemia 7 | 785
aldosterone-producing adenoma 7 | 664
diabetes mellitus 7 | 1,663
nasopharyngeal carcinoma 7 | 1,056
non primary Sjogren syndrome sicca 7 | 840
progressive supranuclear palsy 7 | 674
Atopic dermatitis 6 | 944
Autistic Disorder 6 | 320
Microcephaly 6 | 149
Myocardial Ischemia 6 | 169
adrenocortical carcinoma 6 | 1,427
primary Sjogren syndrome 6 | 788
ARC syndrome 5 | 14
Anemia 5 | 252
Colorectal Neoplasms 5 | 217
Diarrhea 5 | 155
Down syndrome 5 | 548
Epilepsy 5 | 346
Hemochromatosis 5 | 55
IGA Glomerulonephritis 5 | 454
Liver disease 5 | 219
Malaria 5 | 140
Neoplasm Metastasis 5 | 138
Neuropathy 5 | 210
Paraplegia 5 | 71
Tetanus 5 | 66
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
chronic rhinosinusitis 5 | 512
tuberculosis and treatment for 6 months 5 | 686
Becker muscular dystrophy 4 | 187
Juvenile arthritis 4 | 124
Polycystic Ovary Syndrome 4 | 334
Prostate cancer 4 | 172
Prostatic Neoplasms 4 | 471
Schizophrenia 4 | 503

Tissue

Blood and immune system 131 | 17,994
Digestive Tract 131 | 18,472
Endocrine System 131 | 18,511
Female tissues 131 | 18,646
Liver and Pancreas 131 | 18,135
Male tissues 131 | 17,968
Nervous System 131 | 18,560
Respiratory system 131 | 17,483
Skin and soft tissues 131 | 18,114
Urinary Tract 131 | 18,443
Cardiovascular System 130 | 17,957

Target Family

Non-IDG 84 | 11,969
Enzyme 24 | 4,146
Transporter 12 | 473
GPCR 7 | 408
Ion Channel 4 | 341
Kinase 3 | 634
oGPCR 1 | 421

Compartment GO Term

Recycling endosome 135 | 135
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rab15 effector protein REP15 Tbio Non-IDG -0.44863 2.71 15
Vacuolar protein sorting-associated protein 53 homolog VPS53 Tbio Non-IDG -0.76155 5.77 94
Rab11 family-interacting protein 5 RAB11FIP5 Tbio Non-IDG -1.49558 32.9 56
Atypical chemokine receptor 3 ACKR3 Tchem GPCR -1.80879 81.4 385
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.62399 398.9 288
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.38773 26.2 55
Rab11 family-interacting protein 4 RAB11FIP4 Tbio Non-IDG -0.65593 4.75 34
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.63101 403.7 216
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.43730 28.2 91
Protein kinase C and casein kinase substrate in neurons protein 2 PACSIN2 Tbio Enzyme -1.36785 25.7 114