Development Level

Tbio 196 | 11,445
Tdark 15 | 6,588
Tchem 8 | 1,598
Tclin 5 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal behavior 5 | 298
preweaning lethality, incomple... 5 | 499
abnormal embryo size 4 | 220
abnormal sleep behavior 4 | 70
decreased grip strength 4 | 116
decreased mean corpuscular hem... 4 | 50
decreased total body fat amoun... 4 | 207
abnormal retina morphology 3 | 71
embryonic lethality prior to o... 3 | 239
hyperactivity 3 | 148
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal gait 2 | 69
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased leukocyte cell numbe... 2 | 73
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased circulating serum al... 2 | 22
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 96
tremors 2 | 39
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal skin appearance 1 | 3
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal thymus morphology 1 | 7
absent startle reflex 1 | 24
alopecia 1 | 1
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased IgE level 1 | 6
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating lactate ... 1 | 3
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
head bobbing 1 | 5
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
mammalian phenotype 1 | 17
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
small superior vagus ganglion 1 | 74
small thymus 1 | 16
trunk curl 1 | 16

Disease

Carcinoma 128 | 11,493
psoriasis 106 | 6,694
ovarian cancer 100 | 8,520
Cancer 91 | 2,499
osteosarcoma 79 | 7,950
Ankylosing spondylitis 72 | 140
glioblastoma 71 | 5,792
medulloblastoma, large-cell 71 | 6,241
Behcet's disease 70 | 89
diabetes mellitus 67 | 1,728
Hypersensitivity reaction type II disease 60 | 253
Arthritis 59 | 290
Uveitis 59 | 103
Acquired immunodeficiency syndrome 58 | 197
Juvenile rheumatoid arthritis 58 | 111
Herpes zoster 57 | 68
dermatomyositis 56 | 966
atypical teratoid / rhabdoid tumor 55 | 5,112
Human immunodeficiency virus infectious disease 51 | 138
Psoriatic arthritis 50 | 86
Rheumatoid arthritis 50 | 1,191
Stevens-Johnson syndrome 50 | 92
lung cancer 49 | 4,740
ependymoma 44 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 44 | 3,291
tuberculosis 43 | 2,010
Astrocytoma, Pilocytic 40 | 3,081
Dermatitis 37 | 157
Synovitis 36 | 78
Takayasu's arteritis 36 | 53
adult high grade glioma 36 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 36 | 2,989
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
group 3 medulloblastoma 35 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
non-small cell lung cancer 33 | 2,890
invasive ductal carcinoma 32 | 2,951
malignant mesothelioma 32 | 3,232
subependymal giant cell astrocytoma 31 | 2,287
pancreatic cancer 29 | 2,398
Anemia 28 | 365
Breast cancer 28 | 3,578
Hemochromatosis 28 | 54
Liver disease 28 | 237
lung adenocarcinoma 28 | 2,716
primitive neuroectodermal tumor 28 | 3,035
astrocytic glioma 26 | 2,597
oligodendroglioma 26 | 2,850
Kidney disease 25 | 430
Pick disease 25 | 1,894
Hepatitis B 24 | 108
Kidney cancer 24 | 2,613
lung carcinoma 24 | 2,843
Multiple Sclerosis 23 | 540
ulcerative colitis 23 | 1,819
Leprosy 22 | 73
Multiple myeloma 22 | 1,332
Primary immunodeficiency disease 22 | 54
juvenile dermatomyositis 22 | 1,187
Birdshot chorioretinopathy 21 | 23
Skin disease 21 | 66
pituitary cancer 21 | 1,972
astrocytoma 20 | 1,146
breast carcinoma 20 | 1,638
ductal carcinoma in situ 20 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
gastric carcinoma 17 | 807
group 4 medulloblastoma 17 | 1,855
interstitial cystitis 17 | 2,312
pediatric high grade glioma 17 | 1,064
colon cancer 16 | 1,478
primary pancreatic ductal adenocarcinoma 16 | 1,109
Autosomal recessive predisposition 15 | 1,442
Pre-Eclampsia 15 | 68
acute quadriplegic myopathy 15 | 1,158
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
Schizophrenia 14 | 1,160
esophageal adenocarcinoma 14 | 737
Neurodegenerative disease 13 | 414
active Crohn's disease 13 | 922
cutaneous lupus erythematosus 13 | 1,057
cystic fibrosis 13 | 1,696
Duchenne muscular dystrophy 11 | 601
primary Sjogren syndrome 11 | 735
Alzheimer's disease 10 | 658
Epilepsy 10 | 792
Waldenstrons macroglobulinemia 10 | 765
acute myeloid leukemia 10 | 783
Bipolar Disorder 9 | 666
active ulcerative colitis 9 | 764
adrenocortical carcinoma 9 | 1,428
fibroadenoma 9 | 559
non primary Sjogren syndrome sicca 9 | 891
spina bifida 9 | 1,074

Tissue

Digestive Tract 151 | 17,369
Endocrine System 151 | 18,159
Female tissues 149 | 17,400
Liver and Pancreas 149 | 16,750
Nervous System 149 | 16,725
Respiratory system 149 | 16,393
Male tissues 148 | 17,142
Skin and soft tissues 148 | 17,230
Urinary Tract 148 | 16,678
Blood and immune system 147 | 16,909
Cardiovascular System 143 | 15,192

Target Family

Non-IDG 166 | 12,091
Enzyme 28 | 4,145
Transporter 13 | 473
GPCR 7 | 408
Ion Channel 5 | 344
Kinase 4 | 634
oGPCR 1 | 421

Compartment GO Term

Recycling endosome 224 | 224
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182
Rab15 effector protein REP15 Tbio Non-IDG -0.44863 2.71 21
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Protein unc-13 homolog D UNC13D Tbio Non-IDG -1.93790 85.1 158
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Secretory carrier-associated membrane protein 2 SCAMP2 Tbio Non-IDG -1.03513 11.2 191
Serine/threonine-protein kinase LMTK2 LMTK2 Tbio Kinase -1.46351 31.6 189
Ras-related protein Rap-2b RAP2B Tbio Enzyme -2.39691 181.1 192