Development Level

Tbio 6 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal iris morphology 1 | 13
abnormal retina morphology 1 | 71
increased lymphocyte cell numb... 1 | 32
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 6 | 11,493
osteosarcoma 6 | 7,950
atypical teratoid / rhabdoid tumor 5 | 5,112
medulloblastoma, large-cell 5 | 6,241
Choroideremia 4 | 16
Hermansky-Pudlak syndrome 4 | 42
adult high grade glioma 4 | 3,801
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
malignant mesothelioma 3 | 3,232
Autosomal recessive predisposition 2 | 1,442
Chediak-Higashi syndrome 2 | 26
Epilepsy 2 | 792
Griscelli syndrome 2 | 24
Griscelli syndrome type 2 2 | 12
Hair hypopigmentation 2 | 12
Hemophagocytic lymphohistiocytosis 2 | 30
Hepatomegaly 2 | 285
Hypopigmentation disorder 2 | 25
Icterus 2 | 82
Immunologic Deficiency Syndromes 2 | 113
Low Vision 2 | 174
Lymphadenopathy 2 | 62
Neutrophil count decreased 2 | 47
Oculocutaneous albinism 2 | 29
Pick disease 2 | 1,894
Seizures 2 | 596
Splenomegaly 2 | 190
Visual Impairment 2 | 174
astrocytic glioma 2 | 2,597
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
Abnormality of retinal pigmentation 1 | 111
Amblyopia 1 | 38
Blindness 1 | 88
Blood Coagulation Disorders 1 | 42
Chorioretinal atrophy 1 | 11
Choroidal sclerosis 1 | 8
Coagulation abnormalities 1 | 27
Decreased nerve conduction velocity 1 | 35
Decreased platelet count 1 | 111
Decreased tendon reflex 1 | 122
Decreased visual acuity, progressive 1 | 36
Difficulties with night vision 1 | 87
Ecchymosis 1 | 66
Epistaxis 1 | 43
Exfoliation Syndrome 1 | 12
Fever 1 | 138
Gaucher disease type 1 1 | 180
Gingival Diseases 1 | 19
Gingival Hemorrhage 1 | 18
Hemorrhagic Disorders 1 | 30
Hyperlipidemia 1 | 43
Increased susceptibility to bacterial infections 1 | 42
Increased tendency to bruise 1 | 66
Infantile onset 1 | 238
Leukopenia 1 | 72
Lymphoma 1 | 81
Myopia 1 | 176
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Night Blindness 1 | 101
Pancytopenia 1 | 45
Paresthesia 1 | 32
Periodontal Diseases 1 | 21
Peripheral Neuropathy 1 | 134
Photodysphoria 1 | 121
Photophobia 1 | 121
Pigment dispersion syndrome 1 | 11
Pigmentary iris degeneration 1 | 20
Platelet storage pool deficiency 1 | 21
Progressive peripheral neuropathy 1 | 3
Progressive visual loss 1 | 36
Prone to bacterial infection 1 | 42
Recurrent bacterial infection 1 | 42
Recurrent respiratory infections 1 | 141
Retinal pigment epithelial abnormality 1 | 111
Skin Ulcer 1 | 48
Systemic lupus erythematosus 1 | 194
Thrombocytopenia 1 | 197
Tremor 1 | 113
Visual field constriction 1 | 36
X-linked dominant 1 | 57
facioscapulohumeral dystrophy 1 | 288
posterior fossa group A ependymoma 1 | 468

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 6 | 4,145
Non-IDG 3 | 12,091

Compartment GO Term

Rab-protein geranylgeranyltran... 9 | 9
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysosomal-trafficking regulator LYST Tbio Non-IDG -1.96473 92.5 15
Rab proteins geranylgeranyltransferase component A 2 CHML Tbio Enzyme -1.90137 73.3 126
Rab proteins geranylgeranyltransferase component A 1 CHM Tbio Enzyme -2.49909 300.2 109
Vacuolar protein sorting-associated protein 33A VPS33A Tbio Non-IDG -0.94266 9.42 45
Chondrolectin CHODL Tbio Non-IDG -0.89081 9.13 76
Geranylgeranyl transferase type-2 subunit beta RABGGTB Tbio Enzyme -0.69980 4.51 47
Ras-related protein Rab-27A RAB27A Tchem Enzyme -2.30319 204.9 308
Ras-related protein Rab-42 RAB42 Tdark Enzyme 0.48 0.20 47
Geranylgeranyl transferase type-2 subunit alpha RABGGTA Tdark Enzyme -0.64015 4.31 53