Development Level

Tbio 313 | 11,651
Tchem 49 | 1,388
Tdark 32 | 6,593
Tclin 15 | 612

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 10 | 499
abnormal heart morphology 8 | 162
decreased vertical activity 8 | 208
enlarged heart 8 | 210
decreased total body fat amoun... 7 | 207
abnormal behavior 6 | 298
decreased body weight 6 | 161
abnormal coat-hair pigmentatio... 5 | 64
abnormal seminal vesicle morph... 5 | 114
decreased body length 5 | 101
decreased bone mineral content 5 | 151
decreased mean corpuscular vol... 5 | 79
abnormal embryo size 4 | 220
abnormal femur morphology 4 | 14
abnormal kidney morphology 4 | 65
cataract 4 | 92
decreased bone mineral density 4 | 126
increased heart weight 4 | 62
increased or absent threshold ... 4 | 101
short tibia 4 | 97
abnormal bone structure 3 | 187
abnormal eye morphology 3 | 68
abnormal humerus morphology 3 | 11
abnormal lens morphology 3 | 81
abnormal retina morphology 3 | 71
abnormal skin morphology 3 | 50
abnormal tooth morphology 3 | 24
decreased circulating choleste... 3 | 93
decreased grip strength 3 | 116
decreased mean corpuscular hem... 3 | 50
hyperactivity 3 | 148
impaired glucose tolerance 3 | 75
impaired righting response 3 | 26
improved glucose tolerance 3 | 79
increased circulating alkaline... 3 | 122
increased circulating triglyce... 3 | 42
increased red blood cell distr... 3 | 34
abnormal behavioral response t... 2 | 66
abnormal cranium morphology 2 | 36
abnormal pelvic girdle bone mo... 2 | 12
abnormal radius morphology 2 | 8
abnormal snout morphology 2 | 23
abnormal tail morphology 2 | 25
abnormal testis morphology 2 | 43
abnormal tibia morphology 2 | 14
abnormal ulna morphology 2 | 8
decreased blood urea nitrogen ... 2 | 51
decreased circulating aspartat... 2 | 34
decreased circulating bilirubi... 2 | 19
decreased circulating free fat... 2 | 31
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 31
decreased neutrophil cell numb... 2 | 42
embryonic lethality prior to t... 2 | 278
enlarged kidney 2 | 14
hypoactivity 2 | 132
impaired pupillary reflex 2 | 26
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating creatini... 2 | 38
increased large unstained cell... 2 | 5
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
mammalian phenotype 2 | 17
persistence of hyaloid vascula... 2 | 33
prolonged ST segment 2 | 36
small testis 2 | 58
abnormal ear morphology 1 | 9
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal spleen morphology 1 | 55
decreased T cell number 1 | 15
decreased circulating amylase ... 1 | 28
decreased circulating iron lev... 1 | 32
decreased hematocrit 1 | 46
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
increased body weight 1 | 25
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 321 | 11,493
ovarian cancer 217 | 8,520
psoriasis 199 | 6,694
glioblastoma 181 | 5,792
Breast cancer 161 | 3,578
osteosarcoma 161 | 7,950
ependymoma 153 | 4,679
Cancer 143 | 2,499
atypical teratoid / rhabdoid tumor 142 | 5,112
invasive ductal carcinoma 138 | 2,951
lung cancer 138 | 4,740
pancreatic cancer 137 | 2,398
Astrocytoma, Pilocytic 136 | 3,081
malignant mesothelioma 133 | 3,232
medulloblastoma, large-cell 133 | 6,241
lung carcinoma 127 | 2,843
Kidney cancer 124 | 2,613
non-small cell lung cancer 122 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 120 | 2,955
lung adenocarcinoma 117 | 2,716
cystic fibrosis 115 | 1,696
adult high grade glioma 114 | 3,801
interstitial cystitis 114 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 112 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 109 | 3,291
ulcerative colitis 98 | 1,819
breast carcinoma 96 | 1,638
ductal carcinoma in situ 95 | 1,745
Autosomal recessive predisposition 94 | 1,442
pituitary cancer 90 | 1,972
diabetes mellitus 81 | 1,728
primary pancreatic ductal adenocarcinoma 81 | 1,109
oligodendroglioma 78 | 2,850
group 3 medulloblastoma 74 | 4,104
primitive neuroectodermal tumor 70 | 3,035
Duchenne muscular dystrophy 69 | 601
Kidney disease 68 | 430
adrenocortical carcinoma 68 | 1,428
gastric carcinoma 68 | 807
subependymal giant cell astrocytoma 66 | 2,287
astrocytic glioma 65 | 2,597
colon cancer 65 | 1,478
Liver Cirrhosis, Experimental 61 | 769
Atopic dermatitis 58 | 952
autosomal dominant Emery-Dreifuss muscular dystrophy 58 | 510
Melanoma 57 | 711
nasopharyngeal carcinoma 57 | 1,058
juvenile dermatomyositis 54 | 1,187
Liver cancer 53 | 604
pancreatic ductal adenocarcinoma liver metastasis 52 | 1,962
tuberculosis 52 | 2,010
group 4 medulloblastoma 51 | 1,855
cutaneous lupus erythematosus 49 | 1,057
Skin cancer 48 | 469
Schizophrenia 47 | 1,160
Heart disease 44 | 306
Rheumatoid arthritis 44 | 1,191
Atherosclerosis 43 | 291
Hypertension 43 | 396
esophageal adenocarcinoma 43 | 737
fibroadenoma 43 | 559
limb girdle muscular dystrophy 2A 42 | 213
Becker muscular dystrophy 41 | 191
Osteoporosis 41 | 363
Arthritis 40 | 290
pediatric high grade glioma 40 | 1,064
Obesity 39 | 678
Myopia 38 | 176
Cerebrovascular disease 37 | 238
Liver disease 37 | 237
Neoplasm Invasiveness 37 | 161
interstitial lung disease 37 | 298
Endometriosis 36 | 540
Short stature 36 | 531
Coronary artery disease 35 | 268
acute quadriplegic myopathy 35 | 1,158
Breast Neoplasms 34 | 445
Osteoarthritis 34 | 184
Prostatic Neoplasms 34 | 495
Abortion, Spontaneous 33 | 109
Lung disease 33 | 142
Mammary Neoplasms 33 | 425
Spontaneous abortion 33 | 113
Vascular disease 33 | 319
Neoplasm Metastasis 32 | 168
periodontitis 32 | 293
Alzheimer's disease 31 | 658
Anemia 31 | 365
Asthma 31 | 385
Hypersensitivity reaction type II disease 31 | 253
Hypertensive disease 31 | 292
non primary Sjogren syndrome sicca 31 | 891
sonic hedgehog group medulloblastoma 31 | 467
Cataract 30 | 297
Hypoplastic mandible condyle 30 | 275
Intellectual disability 30 | 1,016
Mandibular hypoplasia 30 | 275
Micrognathism 30 | 275
Multiple Sclerosis 30 | 540
urothelial carcinoma 30 | 318

Tissue

Endocrine System 392 | 18,159
Female tissues 384 | 17,400
Digestive Tract 383 | 17,369
Skin and soft tissues 377 | 17,230
Male tissues 376 | 17,142
Blood and immune system 372 | 16,909
Nervous System 371 | 16,725
Urinary Tract 370 | 16,678
Liver and Pancreas 362 | 16,750
Respiratory system 352 | 16,393
Cardiovascular System 323 | 15,192

Target Family

Non-IDG 323 | 12,091
Enzyme 71 | 4,145
Kinase 8 | 634
Transcription Factor 4 | 1,400
Ion Channel 3 | 344

Compartment GO Term

Proteinaceous extracellular ma... 409 | 409
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Amelogenin, X isoform AMELX Tbio Non-IDG -2.84702 695.0 136
Filaggrin FLG Tbio Non-IDG -3.03594 1055.2 253
Amelogenin, Y isoform AMELY Tbio Non-IDG -2.86429 712.3 22
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
A disintegrin and metalloproteinase with thrombospondin motifs 2 ADAMTS2 Tbio Enzyme -2.51717 1472.5 133
Collagen and calcium-binding EGF domain-containing protein 1 CCBE1 Tbio Non-IDG -1.27652 20.3 165
Nephronectin NPNT Tbio Non-IDG -1.54450 37.2 104