Development Level

Tbio 292 | 10,625
Tchem 80 | 1,890
Tdark 24 | 7,003
Tclin 16 | 602

IMPC Term

preweaning lethality, complete... 13 | 633
abnormal behavior 7 | 226
decreased grip strength 6 | 123
decreased lean body mass 6 | 195
enlarged heart 6 | 111
short tibia 6 | 82
abnormal coat/hair pigmentatio... 5 | 54
abnormal lens morphology 5 | 73
abnormal retina morphology 5 | 100
decreased body length 5 | 108
decreased body weight 5 | 174
decreased bone mineral content 5 | 157
decreased total body fat amoun... 5 | 186
increased circulating alkaline... 5 | 119
preweaning lethality, incomple... 5 | 260
abnormal femur morphology 4 | 14
abnormal heart morphology 4 | 51
abnormal tooth morphology 4 | 24
decreased bone mineral density 4 | 126
abnormal humerus morphology 3 | 11
abnormal retinal blood vessel ... 3 | 18
abnormal seminal vesicle morph... 3 | 47
cataract 3 | 26
decreased circulating glucose ... 3 | 121
decreased circulating insulin ... 3 | 75
decreased circulating serum al... 3 | 79
decreased heart weight 3 | 44
decreased mean corpuscular hem... 3 | 34
decreased mean corpuscular vol... 3 | 50
impaired glucose tolerance 3 | 52
impaired righting response 3 | 19
increased blood urea nitrogen ... 3 | 44
increased exploration in new e... 3 | 56
increased or absent threshold ... 3 | 128
persistence of hyaloid vascula... 3 | 22
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
abnormal cranium morphology 2 | 32
abnormal embryo size 2 | 112
abnormal eye morphology 2 | 38
abnormal iris morphology 2 | 12
abnormal kidney morphology 2 | 30
abnormal pelvic girdle bone mo... 2 | 11
abnormal radius morphology 2 | 8
abnormal retinal pigmentation 2 | 61
abnormal retinal vasculature m... 2 | 15
abnormal snout morphology 2 | 18
abnormal testis morphology 2 | 30
abnormal tibia morphology 2 | 14
abnormal ulna morphology 2 | 8
decreased circulating choleste... 2 | 85
decreased circulating free fat... 2 | 39
decreased circulating total pr... 2 | 41
decreased erythrocyte cell num... 2 | 43
decreased hemoglobin content 2 | 53
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 19
hydrops fetalis 2 | 22
hyperactivity 2 | 108
impaired pupillary reflex 2 | 14
improved glucose tolerance 2 | 56
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating bilirubi... 2 | 16
increased circulating choleste... 2 | 53
increased hemoglobin content 2 | 45
increased vertical activity 2 | 18
mydriasis 2 | 9
polycystic kidney 2 | 9
polydactyly 2 | 22
small testis 2 | 37
abnormal coping response 1 | 12
abnormal ear morphology 1 | 5
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal locomotor activation 1 | 26
abnormal lymph node morphology 1 | 3
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased cervical vertebrae n... 1 | 12
decreased circulating bilirubi... 1 | 14
decreased circulating sodium l... 1 | 18
decreased eosinophil cell numb... 1 | 41
decreased lumbar vertebrae num... 1 | 62
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
enlarged spleen 1 | 26
increased circulating creatini... 1 | 29
increased circulating triglyce... 1 | 24
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
limb grasping 1 | 35
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 227 | 8,484
psoriasis 210 | 6,685
glioblastoma 175 | 5,572
osteosarcoma 163 | 7,933
Cancer 162 | 2,346
invasive ductal carcinoma 146 | 2,950
pilocytic astrocytoma 142 | 3,086
lung cancer 140 | 4,466
medulloblastoma, large-cell 136 | 6,234
pancreatic cancer 136 | 2,300
Breast cancer 134 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 134 | 2,956
lung carcinoma 132 | 2,844
malignant mesothelioma 132 | 3,162
atypical teratoid / rhabdoid tumor 127 | 4,369
non-small cell lung cancer 126 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 123 | 2,988
lung adenocarcinoma 121 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 119 | 3,289
cystic fibrosis 116 | 1,665
interstitial cystitis 115 | 2,299
Carcinoma 112 | 2,147
ulcerative colitis 112 | 2,087
pediatric high grade glioma 107 | 2,712
primary pancreatic ductal adenocarcinoma 102 | 1,271
posterior fossa group A ependymoma 100 | 1,511
breast carcinoma 99 | 1,614
ductal carcinoma in situ 98 | 1,745
pituitary cancer 92 | 1,972
sonic hedgehog group medulloblastoma 86 | 1,482
oligodendroglioma 84 | 2,849
diabetes mellitus 83 | 1,663
Duchenne muscular dystrophy 75 | 602
gastric carcinoma 74 | 832
primitive neuroectodermal tumor 72 | 3,031
subependymal giant cell astrocytoma 72 | 2,287
Kidney disease 71 | 396
adrenocortical carcinoma 69 | 1,427
colon cancer 69 | 1,475
ependymoma 63 | 2,514
Atopic dermatitis 61 | 944
autosomal dominant Emery-Dreifuss muscular dystrophy 61 | 499
juvenile dermatomyositis 61 | 1,189
nasopharyngeal carcinoma 58 | 1,056
cutaneous lupus erythematosus 54 | 1,056
astrocytic glioma 53 | 2,241
adult high grade glioma 51 | 2,148
Heart disease 47 | 279
tuberculosis 47 | 1,557
Atherosclerosis 46 | 275
fibroadenoma 46 | 557
group 3 medulloblastoma 46 | 2,254
esophageal adenocarcinoma 44 | 737
group 4 medulloblastoma 44 | 1,875
Alzheimer's disease 43 | 644
Rheumatoid Arthritis 43 | 1,160
Arthritis 42 | 248
Becker muscular dystrophy 42 | 187
Cerebrovascular disease 41 | 231
acute quadriplegic myopathy 39 | 1,157
Hypertension 38 | 287
Liver disease 38 | 219
Prostatic Neoplasms 38 | 471
astrocytoma 38 | 1,493
interstitial lung disease 38 | 291
Osteoporosis 37 | 257
limb girdle muscular dystrophy 2A 37 | 156
Endometriosis 35 | 535
Lung disease 35 | 132
Neoplasm Invasiveness 35 | 127
Coronary artery disease 34 | 240
Down syndrome 34 | 548
Obesity 34 | 616
Spontaneous abortion 34 | 108
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,795
Neoplasm Metastasis 32 | 138
Pick disease 32 | 1,893
Mammary Neoplasms 31 | 410
urothelial carcinoma 31 | 318
Asthma 30 | 349
Hypersensitivity reaction type II disease 30 | 235
Vascular disease 30 | 281
dermatomyositis 30 | 933
atypical teratoid/rhabdoid tumor 29 | 1,095
active Crohn's disease 28 | 918
inflammatory breast cancer 28 | 404
periodontitis 28 | 269
posterior fossa group B ependymoma 28 | 1,530
Multiple Sclerosis 27 | 498
Osteoarthritis 27 | 96
non primary Sjogren syndrome sicca 27 | 840
primary Sjogren syndrome 26 | 789
Liver Cirrhosis 25 | 101
Schizophrenia 25 | 501
head and neck cancer and chronic obstructive pulmonary disease 25 | 237
Dementia 24 | 129
Hypertensive disease 24 | 193
Inflammatory bowel disease 24 | 142
Neuropathy 24 | 210
non-small cell lung carcinoma 23 | 413

Tissue

Digestive Tract 406 | 18,473
Endocrine System 406 | 18,512
Female tissues 406 | 18,647
Nervous System 404 | 18,561
Urinary Tract 404 | 18,444
Skin and soft tissues 401 | 18,115
Cardiovascular System 398 | 17,958
Liver and Pancreas 398 | 18,136
Male tissues 397 | 17,969
Blood and immune system 395 | 17,995
Respiratory system 388 | 17,484

Target Family

Non-IDG 326 | 11,971
Enzyme 74 | 4,146
Kinase 7 | 634
Transcription Factor 5 | 1,400

Compartment GO Term

Proteinaceous extracellular ma... 412 | 412
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788