Development Level

Tbio 23 | 10,625
Tchem 18 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal embryo size 2 | 112
abnormal sleep behavior 2 | 63
embryonic lethality prior to o... 2 | 148
increased exploration in new e... 2 | 56
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
cardiovascular system phenotyp... 1 | 35
decreased blood urea nitrogen ... 1 | 31
decreased leukocyte cell numbe... 1 | 54
decreased threshold for audito... 1 | 32
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased fasted circulating g... 1 | 68
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased prepulse inhibition 1 | 21
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 24 | 8,484
osteosarcoma 23 | 7,933
medulloblastoma, large-cell 22 | 6,234
glioblastoma 19 | 5,572
lung cancer 18 | 4,466
Carcinoma 17 | 2,147
interstitial cystitis 16 | 2,299
malignant mesothelioma 14 | 3,162
non-small cell lung cancer 14 | 2,798
psoriasis 14 | 6,685
atypical teratoid / rhabdoid tumor 13 | 4,369
ulcerative colitis 13 | 2,087
Cancer 12 | 2,346
Pick disease 12 | 1,893
oligodendroglioma 11 | 2,849
ependymoma 10 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
lung adenocarcinoma 10 | 2,713
lung carcinoma 10 | 2,844
pediatric high grade glioma 10 | 2,712
Breast cancer 9 | 3,094
adult high grade glioma 9 | 2,148
group 3 medulloblastoma 9 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
astrocytic glioma 8 | 2,241
group 4 medulloblastoma 8 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
invasive ductal carcinoma 8 | 2,950
pilocytic astrocytoma 8 | 3,086
breast carcinoma 7 | 1,614
diabetes mellitus 7 | 1,663
pituitary cancer 7 | 1,972
subependymal giant cell astrocytoma 7 | 2,287
colon cancer 6 | 1,475
cystic fibrosis 6 | 1,665
medulloblastoma 6 | 1,524
pancreatic cancer 6 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
primitive neuroectodermal tumor 6 | 3,031
cutaneous lupus erythematosus 5 | 1,056
juvenile dermatomyositis 5 | 1,189
primary Sjogren syndrome 5 | 789
Crohn's disease 4 | 304
Kidney disease 4 | 396
Multiple myeloma 4 | 1,327
acute quadriplegic myopathy 4 | 1,157
adrenocortical carcinoma 4 | 1,427
astrocytoma 4 | 1,493
dermatomyositis 4 | 933
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
nasopharyngeal carcinoma 4 | 1,056
posterior fossa group A ependymoma 4 | 1,511
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064
tuberculosis 4 | 1,557
Anemia 3 | 252
Arthritis 3 | 248
Celiac disease 3 | 112
Chronic Lymphocytic Leukemia 3 | 242
Duchenne muscular dystrophy 3 | 602
Hypersensitivity reaction type II disease 3 | 235
Melanoma 3 | 261
Multiple Sclerosis 3 | 498
Obesity 3 | 616
Rheumatoid Arthritis 3 | 1,160
aldosterone-producing adenoma 3 | 664
atypical teratoid/rhabdoid tumor 3 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
fibroadenoma 3 | 557
gastric carcinoma 3 | 832
glioblastoma multiforme 3 | 347
non primary Sjogren syndrome sicca 3 | 840
posterior fossa group B ependymoma 3 | 1,530
primary pancreatic ductal adenocarcinoma 3 | 1,271
sonic hedgehog group medulloblastoma 3 | 1,482
Alzheimer's disease 2 | 644
Cognitive disorder 2 | 44
Colitis 2 | 46
Colorectal Neoplasms 2 | 217
Crohn Disease 2 | 97
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Down syndrome 2 | 548
Gaucher disease type 1 2 | 171
Globe disease 2 | 57
Heart disease 2 | 279
IGA Glomerulonephritis 2 | 454
Inflammatory Bowel Diseases 2 | 87
Mammary Neoplasms 2 | 410
Neuroblastoma 2 | 78
Nonsyndromic deafness 2 | 121
Peripheral Neuropathy 2 | 303
Stomach Neoplasms 2 | 282
Vascular disease 2 | 281
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 780
hereditary spastic paraplegia 2 | 313
nephrosclerosis 2 | 329
severe Alzheimer's disease 2 | 49

Tissue

Blood and immune system 43 | 17,995
Cardiovascular System 43 | 17,958
Digestive Tract 43 | 18,473
Endocrine System 43 | 18,512
Female tissues 43 | 18,647
Liver and Pancreas 43 | 18,136
Male tissues 43 | 17,969
Nervous System 43 | 18,561
Respiratory system 43 | 17,484
Skin and soft tissues 43 | 18,115
Urinary Tract 43 | 18,444

Target Family

Enzyme 38 | 4,146
Kinase 2 | 634
Non-IDG 2 | 11,971
Nuclear Receptor 1 | 48

Compartment GO Term

Protein tyrosine phosphatase c... 43 | 43
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

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