Development Level

Tbio 24 | 11,651
Tchem 17 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
abnormal sleep behavior 2 | 70
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
increased lean body mass 2 | 172
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal pericardium morpholog... 1 | 26
cataract 1 | 92
decreased circulating serum al... 1 | 82
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
prolonged ST segment 1 | 36
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

Carcinoma 37 | 11,493
ovarian cancer 24 | 8,520
osteosarcoma 23 | 7,950
medulloblastoma, large-cell 22 | 6,241
glioblastoma 21 | 5,792
lung cancer 20 | 4,740
Kidney cancer 17 | 2,613
interstitial cystitis 16 | 2,312
adult high grade glioma 15 | 3,801
atypical teratoid / rhabdoid tumor 15 | 5,112
ependymoma 15 | 4,679
group 3 medulloblastoma 15 | 4,104
malignant mesothelioma 15 | 3,232
non-small cell lung cancer 14 | 2,890
psoriasis 14 | 6,694
Cancer 13 | 2,499
Pick disease 12 | 1,894
ulcerative colitis 12 | 1,819
oligodendroglioma 11 | 2,850
Breast cancer 10 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung adenocarcinoma 10 | 2,716
lung carcinoma 10 | 2,843
astrocytic glioma 9 | 2,597
diabetes mellitus 9 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Astrocytoma, Pilocytic 8 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
invasive ductal carcinoma 8 | 2,951
Liver Cirrhosis, Experimental 7 | 769
Melanoma 7 | 711
Schizophrenia 7 | 1,160
Skin cancer 7 | 469
breast carcinoma 7 | 1,638
group 4 medulloblastoma 7 | 1,855
pancreatic cancer 7 | 2,398
pituitary cancer 7 | 1,972
subependymal giant cell astrocytoma 7 | 2,287
Autosomal recessive predisposition 6 | 1,442
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primitive neuroectodermal tumor 6 | 3,035
cutaneous lupus erythematosus 5 | 1,057
juvenile dermatomyositis 5 | 1,187
Arthritis 4 | 290
Chronic Lymphocytic Leukemia 4 | 262
Crohn's disease 4 | 321
Kidney disease 4 | 430
Liver cancer 4 | 604
Multiple myeloma 4 | 1,332
Rheumatoid arthritis 4 | 1,191
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735
progressive supranuclear palsy 4 | 676
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
Angle class 2 malocclusion 3 | 57
Angle class 3 malocclusion 3 | 57
Arthralgia 3 | 90
Arthritis, Rheumatoid 3 | 174
Carcinoma of colon 3 | 32
Celiac disease 3 | 116
Cognitive disorder 3 | 50
Colorectal Neoplasms 3 | 243
Decreased joint mobility 3 | 53
Duchenne muscular dystrophy 3 | 601
Endometrial cancer 3 | 311
Fatigue 3 | 182
Heart disease 3 | 306
Hypersensitivity reaction type II disease 3 | 253
Lymphoid leukemia 3 | 160
Malocclusion 3 | 57
Multiple Sclerosis 3 | 540
Obesity 3 | 678
Stomach Neoplasms 3 | 300
Type 2 diabetes mellitus 3 | 272
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
primary pancreatic ductal adenocarcinoma 3 | 1,109
Alzheimer's disease 2 | 658
Byzanthine arch palate 2 | 194
Chronic obstructive pulmonary disease 2 | 184
Down syndrome 2 | 499
Epilepsy 2 | 792
Hepatomegaly 2 | 285
Vascular disease 2 | 319
Waldenstrons macroglobulinemia 2 | 765
nephrosclerosis 2 | 333

Tissue

Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Skin and soft tissues 43 | 17,230
Blood and immune system 42 | 16,909
Cardiovascular System 42 | 15,192
Male tissues 42 | 17,142
Respiratory system 42 | 16,393
Urinary Tract 42 | 16,678
Nervous System 41 | 16,725

Target Family

Enzyme 38 | 4,145
Kinase 2 | 634
Non-IDG 2 | 12,091
Nuclear Receptor 1 | 48

Compartment GO Term

Protein tyrosine phosphatase c... 43 | 43
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein phosphatase non-receptor type 5 PTPN5 Tchem Enzyme -1.85420 70.8 225
Tyrosine-protein phosphatase non-receptor type 22 PTPN22 Tchem Enzyme -2.70715 543.9 211
Tyrosine-protein phosphatase non-receptor type 2 PTPN2 Tchem Enzyme -2.53451 297.2 192
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.11032 1400.0 1077
Low molecular weight phosphotyrosine protein phosphatase ACP1 Tchem Enzyme -2.44793 295.3 248
Leukocyte surface antigen CD47 CD47 Tbio Non-IDG -2.72897 566.3 746
Tyrosine-protein phosphatase non-receptor type 12 PTPN12 Tchem Enzyme -1.81716 68.8 125
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -4.00292 9201.7 1455
Receptor-type tyrosine-protein phosphatase C PTPRC Tchem Enzyme -3.69291 4643.0 0
Receptor-type tyrosine-protein phosphatase delta PTPRD Tbio Enzyme -2.31841 199.3 102