Development Level

Tbio 34 | 10,625
Tchem 8 | 1,890
Tdark 4 | 7,003
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal bone structure 1 | 131
abnormal heart left ventricle ... 1 | 20
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal retina morphology 1 | 100
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased effector memory CD8-... 1 | 24
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased macrophage cell numb... 1 | 4
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased memory-marker CD4-ne... 1 | 4
hyperactivity 1 | 108
hypoactivity 1 | 89
immune system phenotype 1 | 17
increased CD4-negative NK T ce... 1 | 4
increased startle reflex 1 | 38
long tibia 1 | 13
male infertility 1 | 62
thrombocytopenia 1 | 46

Disease

ovarian cancer 32 | 8,492
medulloblastoma, large-cell 24 | 6,234
psoriasis 24 | 6,685
osteosarcoma 23 | 7,933
atypical teratoid / rhabdoid tumor 22 | 4,369
glioblastoma 20 | 5,572
primitive neuroectodermal tumor 15 | 3,031
Breast cancer 13 | 3,099
Cancer 13 | 2,346
Pick disease 12 | 1,893
ependymoma 12 | 2,514
lung cancer 12 | 4,473
Multiple myeloma 11 | 1,328
adult high grade glioma 11 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
lung adenocarcinoma 10 | 2,714
malignant mesothelioma 10 | 3,163
oligodendroglioma 10 | 2,849
pilocytic astrocytoma 10 | 3,086
subependymal giant cell astrocytoma 10 | 2,287
astrocytic glioma 9 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
Waldenstrons macroglobulinemia 8 | 765
colon cancer 8 | 1,475
medulloblastoma 8 | 1,524
pediatric high grade glioma 8 | 2,712
diabetes mellitus 7 | 1,663
group 4 medulloblastoma 7 | 1,875
invasive ductal carcinoma 7 | 2,950
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
sonic hedgehog group medulloblastoma 7 | 1,482
spina bifida 7 | 1,064
Rheumatoid Arthritis 6 | 1,171
astrocytoma 6 | 1,493
non-small cell lung cancer 6 | 2,798
tuberculosis and treatment for 6 months 6 | 686
aldosterone-producing adenoma 5 | 664
gastric carcinoma 5 | 832
group 3 medulloblastoma 5 | 2,254
interstitial cystitis 5 | 2,299
posterior fossa group B ependymoma 5 | 1,530
ulcerative colitis 5 | 2,087
Alzheimer's disease 4 | 644
Carcinoma 4 | 2,147
Toxic encephalopathy 4 | 131
acute quadriplegic myopathy 4 | 1,157
hepatocellular carcinoma 4 | 550
interstitial lung disease 4 | 292
juvenile dermatomyositis 4 | 1,189
lung carcinoma 4 | 2,844
pancreatic cancer 4 | 2,300
pituitary cancer 4 | 1,972
Atopic dermatitis 3 | 944
Hypertension 3 | 293
Intellectual disability 3 | 573
Obesity 3 | 616
Pathological accumulation of air in tissues 3 | 11
acute myeloid leukemia 3 | 785
atypical teratoid/rhabdoid tumor 3 | 1,095
breast carcinoma 3 | 1,614
dermatomyositis 3 | 967
hereditary spastic paraplegia 3 | 313
non primary Sjogren syndrome sicca 3 | 840
posterior fossa group A ependymoma 3 | 1,511
tuberculosis 3 | 1,563
Acquired immunodeficiency syndrome 2 | 164
Acquired metabolic disease 2 | 267
Amyloidosis 2 | 68
Cerebrovascular disease 2 | 231
Chromosomal Instability 2 | 4
Congenital stationary night blindness 2 | 28
Disease Progression 2 | 125
Heart disease 2 | 279
Hepatolenticular Degeneration 2 | 24
Keratoconjunctivitis sicca 2 | 19
Kidney disease 2 | 397
Left Ventricular Hypertrophy 2 | 24
Micronuclei, Chromosome-Defective 2 | 20
Myocardial Ischemia 2 | 169
Noonan Syndrome 2 | 33
Parkinson's disease 2 | 364
Peripheral Neuropathy 2 | 303
Schizophrenia 2 | 503
Spinocerebellar ataxia type 12 2 | 4
Stomach Neoplasms 2 | 282
chronic lymphocytic leukemia 2 | 244
chronic rhinosinusitis 2 | 512
ductal carcinoma in situ 2 | 1,745
tuberculosis and treatment for 3 months 2 | 327
Ataxia, Spinocerebellar 1 | 15
Congenital heart disease 1 | 63
Essential tremor 1 | 30
Exhibitionism 1 | 7
Fatty Liver 1 | 48
Friedreich ataxia 1 | 23
Progressive multifocal leukoencephalopathy 1 | 24
Spinocerebellar ataxia type 1 1 | 16
ovarian neoplasm 1 | 97
type I diabetes mellitus 1 | 22

Tissue

Blood and immune system 46 | 17,995
Cardiovascular System 46 | 17,958
Digestive Tract 46 | 18,473
Endocrine System 46 | 18,512
Female tissues 46 | 18,647
Liver and Pancreas 46 | 18,136
Male tissues 46 | 17,969
Nervous System 46 | 18,561
Urinary Tract 46 | 18,444
Respiratory system 45 | 17,484
Skin and soft tissues 45 | 18,115

Target Family

Enzyme 34 | 4,146
Non-IDG 8 | 11,969
Transcription Factor 5 | 1,400

Compartment GO Term

Protein serine/threonine phosp... 47 | 47
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

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