Development Level

Tbio 40 | 11,445
Tchem 7 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal bone structure 2 | 187
increased fasted circulating g... 2 | 76
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal skin morphology 1 | 50
anophthalmia 1 | 33
brachydactyly 1 | 19
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased threshold for audito... 1 | 26
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
male infertility 1 | 123
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
syndactyly 1 | 23
thrombocytopenia 1 | 56

Disease

ovarian cancer 35 | 8,520
Carcinoma 29 | 11,493
medulloblastoma, large-cell 28 | 6,241
atypical teratoid / rhabdoid tumor 27 | 5,112
osteosarcoma 27 | 7,950
psoriasis 26 | 6,694
glioblastoma 24 | 5,792
ependymoma 20 | 4,679
adult high grade glioma 18 | 3,801
Cancer 17 | 2,499
primitive neuroectodermal tumor 17 | 3,035
lung cancer 15 | 4,740
Breast cancer 14 | 3,578
group 3 medulloblastoma 14 | 4,104
Pick disease 13 | 1,894
astrocytic glioma 13 | 2,597
subependymal giant cell astrocytoma 13 | 2,287
Astrocytoma, Pilocytic 12 | 3,081
Multiple myeloma 12 | 1,332
oligodendroglioma 12 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
malignant mesothelioma 11 | 3,232
Kidney cancer 10 | 2,613
lung adenocarcinoma 10 | 2,716
colon cancer 9 | 1,478
diabetes mellitus 9 | 1,728
group 4 medulloblastoma 9 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
Waldenstrons macroglobulinemia 8 | 765
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Alzheimer's disease 7 | 658
non-small cell lung cancer 7 | 2,890
spina bifida 7 | 1,074
tuberculosis 7 | 2,010
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
Toxic encephalopathy 6 | 141
interstitial cystitis 6 | 2,312
medulloblastoma 6 | 720
Hypertension 5 | 396
aldosterone-producing adenoma 5 | 665
gastric carcinoma 5 | 807
Amyloidosis 4 | 67
Cerebrovascular disease 4 | 238
Epilepsy 4 | 792
Heart disease 4 | 306
Intellectual disability 4 | 1,016
active ulcerative colitis 4 | 764
acute quadriplegic myopathy 4 | 1,158
dermatomyositis 4 | 966
hepatocellular carcinoma 4 | 547
interstitial lung disease 4 | 298
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
tuberculosis and treatment for 6 months 4 | 409
ulcerative colitis 4 | 1,819
Aspergillosis 3 | 26
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Emphysema 3 | 12
Idiopathic scoliosis 3 | 31
Long QT syndrome 1 3 | 20
Malignant hyperthermia 3 | 26
Multiple epiphyseal dysplasia 3 | 18
Otitis externa 3 | 10
Pathological accumulation of air in tissues 3 | 10
Pertussis 3 | 20
Pseudoachondroplasia 3 | 14
Spinocerebellar ataxia type 12 3 | 5
Sporotrichosis 3 | 10
Supraventricular arrhythmia 3 | 4
Tetanus 3 | 68
Ventricular arrhythmia 3 | 27
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
hereditary spastic paraplegia 3 | 318
non primary Sjogren syndrome sicca 3 | 891
pediatric high grade glioma 3 | 1,064
Acquired metabolic disease 2 | 336
Anteverted nostril 2 | 191
Chronic Lymphocytic Leukemia 2 | 262
Congenital stationary night blindness 2 | 29
Disease Progression 2 | 136
Down syndrome 2 | 499
Kidney disease 2 | 430
Melanoma 2 | 711
Myocardial Ischemia 2 | 169
Parkinson's disease 2 | 392
Pectus excavatum 2 | 100
Stomach Neoplasms 2 | 300
active Crohn's disease 2 | 922
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
primary Sjogren syndrome 2 | 735

Tissue

Blood and immune system 51 | 16,909
Cardiovascular System 51 | 15,192
Digestive Tract 51 | 17,369
Endocrine System 51 | 18,159
Female tissues 51 | 17,400
Liver and Pancreas 51 | 16,750
Male tissues 51 | 17,142
Nervous System 51 | 16,725
Respiratory system 51 | 16,393
Skin and soft tissues 51 | 17,230
Urinary Tract 51 | 16,678

Target Family

Enzyme 37 | 4,145
Non-IDG 10 | 12,091
Transcription Factor 5 | 1,400

Compartment GO Term

Protein serine/threonine phosp... 52 | 52
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear factor of activated T-cells, cytoplasmic 4 NFATC4 Tbio Transcription Factor -1.93766 88.3 358
Serine/threonine-protein phosphatase 1 regulatory subunit 10 PPP1R10 Tbio Enzyme -1.71843 50.9 110
Serine/threonine-protein phosphatase 4 regulatory subunit 3B PPP4R3B Tbio Enzyme -1.46618 28.8 121
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Protein phosphatase inhibitor 2 PPP1R2 Tbio Enzyme -1.20523 26.2 259
Nuclear envelope phosphatase-regulatory subunit 1 CNEP1R1 Tbio Enzyme 0.32 0.61 9
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
Leucine-rich repeat protein SHOC-2 SHOC2 Tbio Non-IDG -1.68905 52.6 162
Calcineurin subunit B type 1 PPP3R1 Tbio Non-IDG -2.60752 391.4 125
Myosin phosphatase Rho-interacting protein MPRIP Tbio Enzyme -1.16270 14.3 148