Development Level

Tbio 118 | 11,651
Tchem 47 | 1,388
Tclin 22 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to o... 5 | 239
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
embryonic lethality prior to t... 4 | 278
abnormal embryo size 3 | 220
decreased body weight 3 | 161
enlarged heart 3 | 210
increased leukocyte cell numbe... 3 | 47
increased neutrophil cell numb... 3 | 46
increased total body fat amoun... 3 | 134
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
abnormal femur morphology 2 | 14
abnormal heart morphology 2 | 162
abnormal humerus morphology 2 | 11
abnormal lung morphology 2 | 26
abnormal retina morphology 2 | 71
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
hemorrhage 2 | 23
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
increased spleen weight 2 | 10
short tibia 2 | 97
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased IgG3 level 1 | 1
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased CD4-positive, alpha ... 1 | 4
increased IgM level 1 | 1
increased T cell number 1 | 6
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41
male infertility 1 | 123
mammalian phenotype 1 | 17
small superior vagus ganglion 1 | 74
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Cancer 145 | 2,499
Carcinoma 136 | 11,493
glioblastoma 109 | 5,792
osteosarcoma 109 | 7,950
ovarian cancer 107 | 8,520
psoriasis 103 | 6,694
lung cancer 91 | 4,740
interstitial cystitis 85 | 2,312
invasive ductal carcinoma 85 | 2,951
ependymoma 78 | 4,679
lung carcinoma 78 | 2,843
Breast cancer 77 | 3,578
Astrocytoma, Pilocytic 75 | 3,081
malignant mesothelioma 74 | 3,232
non-small cell lung cancer 73 | 2,890
pancreatic cancer 73 | 2,398
atypical teratoid / rhabdoid tumor 71 | 5,112
diabetes mellitus 70 | 1,728
ulcerative colitis 70 | 1,819
adult high grade glioma 69 | 3,801
lung adenocarcinoma 65 | 2,716
medulloblastoma, large-cell 65 | 6,241
tuberculosis 63 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 62 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 62 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 57 | 3,291
Kidney disease 54 | 430
cystic fibrosis 51 | 1,696
Liver Cirrhosis, Experimental 49 | 769
Hypersensitivity reaction type II disease 48 | 253
ductal carcinoma in situ 47 | 1,745
Kidney cancer 46 | 2,613
cutaneous lupus erythematosus 46 | 1,057
Arthritis 45 | 290
Heart disease 45 | 306
primary pancreatic ductal adenocarcinoma 45 | 1,109
oligodendroglioma 43 | 2,850
pituitary cancer 43 | 1,972
Multiple Sclerosis 42 | 540
Rheumatoid arthritis 42 | 1,191
subependymal giant cell astrocytoma 42 | 2,287
Atherosclerosis 40 | 291
Schizophrenia 40 | 1,160
breast carcinoma 39 | 1,638
Asthma 38 | 385
Lung disease 38 | 142
Vascular disease 36 | 319
colon cancer 36 | 1,478
Autosomal recessive predisposition 35 | 1,442
astrocytic glioma 35 | 2,597
Coronary artery disease 34 | 268
Neoplasm Invasiveness 34 | 161
Breast Neoplasms 33 | 445
Inflammatory bowel disease 33 | 151
Liver disease 33 | 237
primitive neuroectodermal tumor 33 | 3,035
Anemia 32 | 365
Duchenne muscular dystrophy 32 | 601
Mammary Neoplasms 32 | 425
nasopharyngeal carcinoma 32 | 1,058
Endometriosis 31 | 540
group 3 medulloblastoma 31 | 4,104
periodontitis 31 | 293
Hypertension 30 | 396
Neoplasm Metastasis 30 | 168
Cerebrovascular disease 29 | 238
Dermatitis 29 | 157
gastric carcinoma 29 | 807
Obesity 28 | 678
Prostatic Neoplasms 28 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 28 | 510
juvenile dermatomyositis 28 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
Melanoma 27 | 711
Thrombocytopenia 27 | 197
group 4 medulloblastoma 27 | 1,855
Atopic dermatitis 26 | 952
adrenocortical carcinoma 26 | 1,428
Osteoporosis 25 | 363
Allergic hypersensitivity disease 24 | 126
Pulmonary Fibrosis 24 | 106
esophageal adenocarcinoma 24 | 737
Hypertensive disease 23 | 292
Stomach Neoplasms 23 | 300
dermatomyositis 23 | 966
primary Sjogren syndrome 23 | 735
mucosa-associated lymphoid tissue lymphoma 22 | 484
Alzheimer's disease 21 | 658
Bipolar Disorder 21 | 666
Human immunodeficiency virus infectious disease 21 | 138
sarcoidosis 21 | 370
Influenza 20 | 142
Liver Cirrhosis 20 | 181
Lung Neoplasms 20 | 232
Malaria 20 | 160
Myocardial Ischemia 20 | 169
non primary Sjogren syndrome sicca 20 | 891
pediatric high grade glioma 20 | 1,064
Arthritis, Rheumatoid 19 | 174
acute quadriplegic myopathy 19 | 1,158

Tissue

Endocrine System 184 | 18,159
Female tissues 184 | 17,400
Blood and immune system 182 | 16,909
Digestive Tract 182 | 17,369
Respiratory system 182 | 16,393
Liver and Pancreas 181 | 16,750
Male tissues 181 | 17,142
Skin and soft tissues 181 | 17,230
Urinary Tract 181 | 16,678
Nervous System 177 | 16,725
Cardiovascular System 166 | 15,192

Target Family

Non-IDG 147 | 12,091
Enzyme 27 | 4,145
Kinase 10 | 634
Transcription Factor 3 | 1,400
GPCR 1 | 408

Compartment GO Term

Protein complex involved in ce... 188 | 188
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Galectin-2 LGALS2 Tbio Non-IDG -1.12300 13.4 172
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297
Tyrosine-protein kinase SYK SYK Tchem Kinase -3.14835 1437.4 1136
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
EMILIN-1 EMILIN1 Tbio Non-IDG -1.54226 36.3 0
Integrin alpha-9 ITGA9 Tbio Non-IDG -1.46619 29.0 124
Integrin beta-8 ITGB8 Tbio Non-IDG -1.47947 27.7 99