Development Level

Tbio 84 | 10,625
Tchem 54 | 1,890
Tclin 21 | 602

IMPC Phenotype

preweaning lethality, complete... 7 | 633
abnormal behavior 4 | 226
decreased bone mineral density 3 | 126
increased leukocyte cell numbe... 3 | 37
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal retina morphology 2 | 100
decreased body length 2 | 108
decreased heart weight 2 | 44
decreased leukocyte cell numbe... 2 | 54
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased exploration in new e... 2 | 56
increased vertical activity 2 | 18
abnormal anxiety-related respo... 1 | 1
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal eye anterior chamber ... 1 | 3
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal sleep behavior 1 | 63
abnormal social-conspecific in... 1 | 3
abnormal startle reflex 1 | 14
abnormal tail movements 1 | 12
abnormal vibrissa morphology 1 | 17
decreased B cell number 1 | 30
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
decreased mean corpuscular vol... 1 | 50
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
hyperactivity 1 | 108
impaired righting response 1 | 19
increased CD4-positive, alpha ... 1 | 15
increased IgG1 level 1 | 1
increased T cell number 1 | 15
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular vol... 1 | 91
increased spleen weight 1 | 3
limb grasping 1 | 35
mydriasis 1 | 9
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

Cancer 126 | 2,346
osteosarcoma 96 | 7,933
psoriasis 91 | 6,685
glioblastoma 90 | 5,572
ovarian cancer 89 | 8,491
lung cancer 79 | 4,473
interstitial cystitis 74 | 2,299
invasive ductal carcinoma 69 | 2,950
lung carcinoma 69 | 2,844
non-small cell lung cancer 62 | 2,798
pancreatic cancer 62 | 2,300
ulcerative colitis 62 | 2,087
diabetes mellitus 60 | 1,663
pilocytic astrocytoma 60 | 3,086
malignant mesothelioma 56 | 3,163
intraductal papillary-mucinous carcinoma (IPMC) 54 | 2,988
lung adenocarcinoma 54 | 2,714
tuberculosis 54 | 1,563
medulloblastoma, large-cell 53 | 6,234
intraductal papillary-mucinous adenoma (IPMA) 52 | 2,956
atypical teratoid / rhabdoid tumor 51 | 4,369
Breast cancer 50 | 3,098
intraductal papillary-mucinous neoplasm (IPMN) 50 | 3,289
Kidney disease 45 | 397
primary pancreatic ductal adenocarcinoma 43 | 1,271
Hypersensitivity reaction type II disease 42 | 235
cystic fibrosis 42 | 1,670
pediatric high grade glioma 42 | 2,712
Multiple Sclerosis 41 | 498
cutaneous lupus erythematosus 41 | 1,056
Arthritis 40 | 248
ductal carcinoma in situ 38 | 1,745
Asthma 37 | 349
Rheumatoid Arthritis 36 | 1,170
posterior fossa group A ependymoma 36 | 1,511
pituitary cancer 35 | 1,972
subependymal giant cell astrocytoma 34 | 2,287
Carcinoma 33 | 2,147
Heart disease 33 | 279
Inflammatory bowel disease 33 | 142
Atherosclerosis 32 | 275
Lung disease 32 | 136
oligodendroglioma 32 | 2,849
Vascular disease 30 | 281
colon cancer 29 | 1,475
Liver disease 28 | 219
adult high grade glioma 28 | 2,148
Coronary artery disease 27 | 240
Mammary Neoplasms 26 | 410
breast carcinoma 26 | 1,614
gastric carcinoma 26 | 832
primary Sjogren syndrome 26 | 788
Allergic hypersensitivity disease 25 | 123
Anemia 25 | 252
Cerebrovascular disease 25 | 231
Dermatitis 25 | 141
Neoplasm Metastasis 25 | 138
Prostatic Neoplasms 25 | 471
ependymoma 25 | 2,514
nasopharyngeal carcinoma 25 | 1,056
primitive neuroectodermal tumor 25 | 3,031
Duchenne muscular dystrophy 24 | 602
Hypertension 24 | 293
Neoplasm Invasiveness 23 | 127
astrocytic glioma 23 | 2,241
periodontitis 23 | 269
Endometriosis 22 | 535
Obesity 22 | 616
Thrombocytopenia 22 | 105
dermatomyositis 22 | 966
juvenile dermatomyositis 22 | 1,189
Alzheimer's disease 20 | 644
Human immunodeficiency virus infectious disease 20 | 129
Influenza 20 | 142
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 499
group 4 medulloblastoma 20 | 1,875
mucosa-associated lymphoid tissue lymphoma 20 | 480
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
Eosinophilia 19 | 65
adrenocortical carcinoma 19 | 1,427
sarcoidosis 19 | 368
Malaria 18 | 140
Pulmonary Fibrosis 18 | 66
Stomach Neoplasms 18 | 282
astrocytoma 18 | 1,493
esophageal adenocarcinoma 18 | 737
Atopic dermatitis 17 | 944
IGA Glomerulonephritis 17 | 454
Inflammation 17 | 109
Leukopenia 17 | 42
Lung Neoplasms 17 | 171
Osteoporosis 17 | 259
non-small cell lung carcinoma 17 | 413
Multiple myeloma 16 | 1,327
Myocardial Ischemia 16 | 169
Reperfusion Injury 16 | 84
Vasculitis 16 | 64
Waldenstrons macroglobulinemia 16 | 764
group 3 medulloblastoma 16 | 2,254
sonic hedgehog group medulloblastoma 16 | 1,482

Tissue

Cardiovascular System 158 | 17,957
Digestive Tract 158 | 18,472
Endocrine System 158 | 18,511
Female tissues 158 | 18,646
Nervous System 158 | 18,560
Skin and soft tissues 158 | 18,114
Urinary Tract 158 | 18,443
Blood and immune system 157 | 17,994
Respiratory system 157 | 17,483
Liver and Pancreas 156 | 18,135
Male tissues 156 | 17,968

Target Family

Non-IDG 128 | 11,969
Enzyme 16 | 4,146
Kinase 10 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 408

Compartment GO Term

Protein complex involved in ce... 159 | 159
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
Galectin-3 LGALS3 Tchem Non-IDG -3.33005 2249.5 911
Pro-epidermal growth factor EGF Tbio Non-IDG -3.74596 4837.7 851
Elastin ELN Tbio Non-IDG -3.33458 2025.2 244
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.39396 233.2 634
CD82 antigen CD82 Tbio Non-IDG -2.60792 421.9 340
L-selectin SELL Tchem Non-IDG -3.45880 2781.0 888
Cell adhesion molecule 1 CADM1 Tbio Non-IDG -2.73938 508.3 380
Intercellular adhesion molecule 5 ICAM5 Tbio Non-IDG -1.75361 64.9 170
Collagen alpha-1(XVII) chain COL17A1 Tbio Non-IDG -2.72832 547.0 90