Development Level

Tbio 2,697 | 11,651
Tchem 421 | 1,388
Tdark 318 | 6,593
Tclin 237 | 612

Collection

Kinase: IDG Consortium (Target... 11 | 125
RFA-RM-18-021 11 | 328
Kinase: IDG Consortium (Comple... 3 | 37
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 380 | 979
embryonic lethality prior to t... 126 | 278
embryonic lethality prior to o... 112 | 239
preweaning lethality, incomple... 109 | 499
abnormal embryo size 88 | 220
abnormal behavior 65 | 298
enlarged heart 50 | 210
decreased total body fat amoun... 49 | 207
decreased vertical activity 46 | 208
abnormal bone structure 43 | 187
abnormal heart morphology 41 | 162
decreased bone mineral content 41 | 151
embryonic growth retardation 41 | 106
decreased body weight 40 | 161
increased total body fat amoun... 36 | 134
decreased circulating glucose ... 34 | 126
increased circulating alkaline... 33 | 122
increased lean body mass 33 | 172
abnormal seminal vesicle morph... 32 | 114
hyperactivity 32 | 148
decreased lean body mass 30 | 135
hypoactivity 29 | 132
increased mean corpuscular hem... 28 | 96
abnormal retina morphology 27 | 71
increased mean corpuscular vol... 27 | 92
cataract 26 | 92
decreased body length 26 | 101
increased bone mineral content 26 | 108
male infertility 26 | 123
prenatal lethality prior to he... 26 | 87
abnormal lens morphology 24 | 81
decreased circulating choleste... 24 | 93
decreased bone mineral density 23 | 126
edema 23 | 59
impaired glucose tolerance 23 | 75
increased startle reflex 23 | 112
decreased mean corpuscular vol... 22 | 79
small superior vagus ganglion 22 | 74
decreased grip strength 21 | 116
decreased lymphocyte cell numb... 20 | 83
increased bone mineral density 20 | 72
increased fasted circulating g... 20 | 76
increased heart weight 20 | 62
increased or absent threshold ... 20 | 101
short tibia 20 | 97
abnormal eye morphology 18 | 68
decreased circulating HDL chol... 18 | 68
decreased circulating insulin ... 18 | 76
increased circulating HDL chol... 18 | 80
increased circulating sodium l... 18 | 71
increased grip strength 18 | 41
abnormal kidney morphology 17 | 65
abnormal sleep behavior 17 | 70
decreased circulating serum al... 17 | 82
decreased circulating triglyce... 17 | 79
decreased erythrocyte cell num... 17 | 62
decreased hemoglobin content 17 | 68
decreased leukocyte cell numbe... 17 | 73
increased leukocyte cell numbe... 17 | 47
increased neutrophil cell numb... 17 | 46
abnormal gait 16 | 69
abnormal neural tube closure 16 | 46
decreased fasted circulating g... 16 | 65
decreased prepulse inhibition 16 | 82
improved glucose tolerance 16 | 79
thrombocytopenia 16 | 56
abnormal embryo turning 15 | 31
decreased circulating alkaline... 15 | 46
increased hemoglobin content 15 | 45
small testis 15 | 58
tremors 15 | 39
abnormal pericardium morpholog... 14 | 26
decreased circulating alanine ... 14 | 47
hydrometra 14 | 53
increased circulating triglyce... 14 | 42
increased lymphocyte cell numb... 14 | 32
decreased startle reflex 13 | 75
increased circulating chloride... 13 | 41
increased circulating choleste... 13 | 66
increased monocyte cell number 13 | 63
abnormal behavioral response t... 12 | 66
abnormal coat-hair pigmentatio... 12 | 64
abnormal craniofacial morpholo... 12 | 33
abnormal testis morphology 12 | 43
cardiovascular system phenotyp... 12 | 36
corneal opacity 12 | 32
decreased circulating free fat... 12 | 31
decreased circulating total pr... 12 | 49
decreased mean corpuscular hem... 12 | 50
hemorrhage 12 | 23
pale yolk sac 12 | 25
pallor 12 | 34
abnormal placenta size 11 | 20
abnormal spleen morphology 11 | 55
abnormal tooth morphology 11 | 24
decreased caudal vertebrae num... 11 | 53
decreased circulating fructosa... 11 | 30
decreased hematocrit 11 | 46
persistence of hyaloid vascula... 11 | 33
prolonged ST segment 11 | 36

Disease

Carcinoma 2,278 | 11,493
ovarian cancer 2,061 | 8,520
osteosarcoma 1,713 | 7,950
psoriasis 1,538 | 6,694
Cancer 1,358 | 2,499
lung cancer 1,316 | 4,740
glioblastoma 1,306 | 5,792
medulloblastoma, large-cell 1,264 | 6,241
atypical teratoid / rhabdoid tumor 1,031 | 5,112
ependymoma 947 | 4,679
Breast cancer 936 | 3,578
group 3 medulloblastoma 888 | 4,104
malignant mesothelioma 857 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 767 | 3,291
adult high grade glioma 741 | 3,801
non-small cell lung cancer 737 | 2,890
invasive ductal carcinoma 713 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 700 | 2,989
lung adenocarcinoma 660 | 2,716
Kidney cancer 653 | 2,613
diabetes mellitus 645 | 1,728
lung carcinoma 642 | 2,843
primitive neuroectodermal tumor 634 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 630 | 2,955
Astrocytoma, Pilocytic 624 | 3,081
oligodendroglioma 614 | 2,850
pancreatic cancer 604 | 2,398
tuberculosis 530 | 2,010
astrocytic glioma 518 | 2,597
interstitial cystitis 513 | 2,312
ulcerative colitis 493 | 1,819
Multiple myeloma 485 | 1,332
Autosomal recessive predisposition 484 | 1,442
subependymal giant cell astrocytoma 477 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 465 | 1,962
breast carcinoma 439 | 1,638
colon cancer 416 | 1,478
pituitary cancer 415 | 1,972
ductal carcinoma in situ 413 | 1,745
Pick disease 412 | 1,894
Rheumatoid arthritis 402 | 1,191
cystic fibrosis 383 | 1,696
group 4 medulloblastoma 370 | 1,855
adrenocortical carcinoma 366 | 1,428
Schizophrenia 359 | 1,160
acute quadriplegic myopathy 343 | 1,158
dermatomyositis 330 | 966
juvenile dermatomyositis 330 | 1,187
astrocytoma 328 | 1,146
Intellectual disability 319 | 1,016
cutaneous lupus erythematosus 291 | 1,057
primary pancreatic ductal adenocarcinoma 284 | 1,109
Kidney disease 280 | 430
Waldenstrons macroglobulinemia 279 | 765
nasopharyngeal carcinoma 277 | 1,058
pediatric high grade glioma 270 | 1,064
Epilepsy 257 | 792
Liver Cirrhosis, Experimental 257 | 769
Alzheimer's disease 249 | 658
Obesity 247 | 678
Breast Neoplasms 239 | 445
Arthritis 237 | 290
Atopic dermatitis 237 | 952
Anemia 233 | 365
Short stature 233 | 531
Mammary Neoplasms 229 | 425
Seizures 221 | 596
Multiple Sclerosis 219 | 540
Hypertension 218 | 396
Melanoma 216 | 711
Cognitive delay 212 | 608
Global developmental delay 212 | 608
Mental and motor retardation 212 | 608
Vascular disease 212 | 319
Dull intelligence 211 | 645
Hypersensitivity reaction type II disease 211 | 253
Low intelligence 211 | 645
Mental Retardation 211 | 645
Mental deficiency 211 | 645
Poor school performance 211 | 645
primary Sjogren syndrome 210 | 735
Bipolar Disorder 205 | 666
gastric carcinoma 204 | 807
Duchenne muscular dystrophy 198 | 601
Prostatic Neoplasms 198 | 495
Endometriosis 197 | 540
non primary Sjogren syndrome sicca 195 | 891
spina bifida 195 | 1,074
acute myeloid leukemia 193 | 783
Asthma 191 | 385
active Crohn's disease 187 | 922
Muscle hypotonia 185 | 571
esophageal adenocarcinoma 181 | 737
Atherosclerosis 180 | 291
Heart disease 178 | 306
Cerebrovascular disease 177 | 238
Liver cancer 175 | 604
Coronary artery disease 167 | 268
Depressive disorder 164 | 409
Liver disease 164 | 237

Tissue

Endocrine System 3,509 | 18,159
Digestive Tract 3,473 | 17,369
Female tissues 3,461 | 17,400
Skin and soft tissues 3,460 | 17,230
Male tissues 3,435 | 17,142
Blood and immune system 3,425 | 16,909
Urinary Tract 3,416 | 16,678
Liver and Pancreas 3,415 | 16,750
Respiratory system 3,388 | 16,393
Nervous System 3,384 | 16,725
Cardiovascular System 3,245 | 15,192

Target Family

Non-IDG 2,439 | 12,091
Enzyme 700 | 4,145
Transcription Factor 214 | 1,400
Kinase 161 | 634
Epigenetic 64 | 242
Transporter 33 | 473
GPCR 27 | 408
Nuclear Receptor 17 | 48
Ion Channel 14 | 344
TF/Epigenetic 4 | 38

Compartment GO Term

Protein complex 3,673 | 3,673
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
COP9 signalosome complex subunit 9 COPS9 Tbio Non-IDG 0.21 0.92 14
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
DBIRD complex subunit ZNF326 ZNF326 Tbio Non-IDG -0.42207 3.94 120
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Trafficking protein particle complex subunit 2-like protein TRAPPC2L Tdark Non-IDG -0.18066 0.74 35