Development Level

Tbio 88 | 11,651
Tchem 17 | 1,388
Tdark 7 | 6,593
Tclin 4 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 15 | 979
decreased body weight 6 | 161
preweaning lethality, incomple... 5 | 499
abnormal lens morphology 4 | 81
embryonic lethality prior to o... 4 | 239
abnormal behavior 3 | 298
abnormal cornea morphology 3 | 31
cataract 3 | 92
decreased circulating glucose ... 3 | 126
decreased lean body mass 3 | 135
embryonic lethality prior to t... 3 | 278
increased circulating HDL chol... 3 | 80
increased lean body mass 3 | 172
abnormal eye morphology 2 | 68
abnormal retinal blood vessel ... 2 | 26
corneal opacity 2 | 32
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye pigmentation 1 | 3
abnormal eye size 1 | 7
abnormal eyelid aperture 1 | 2
abnormal gait 1 | 69
abnormal hair texture 1 | 4
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal retinal outer nuclear... 1 | 3
abnormal retinal vasculature m... 1 | 27
abnormal tooth morphology 1 | 24
abnormal vertebral arch morpho... 1 | 9
cardiovascular system phenotyp... 1 | 36
corneal vascularization 1 | 6
decreased IgG2b level 1 | 4
decreased T cell number 1 | 15
decreased cardiac stroke volum... 1 | 6
decreased circulating alkaline... 1 | 46
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
enlarged heart 1 | 210
eyelids fail to open 1 | 3
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased circulating creatine... 1 | 5
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased monocyte cell number 1 | 63
increased respiratory quotient 1 | 2
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
male infertility 1 | 123
mammalian phenotype 1 | 17
mydriasis 1 | 6
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 80 | 11,493
ovarian cancer 79 | 8,520
osteosarcoma 65 | 7,950
lung cancer 35 | 4,740
psoriasis 35 | 6,694
Cancer 34 | 2,499
Breast cancer 31 | 3,578
medulloblastoma, large-cell 31 | 6,241
group 3 medulloblastoma 30 | 4,104
glioblastoma 27 | 5,792
malignant mesothelioma 26 | 3,232
atypical teratoid / rhabdoid tumor 25 | 5,112
Kidney cancer 23 | 2,613
Multiple myeloma 21 | 1,332
Intellectual disability 20 | 1,016
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
primitive neuroectodermal tumor 18 | 3,035
ependymoma 17 | 4,679
oligodendroglioma 16 | 2,850
subependymal giant cell astrocytoma 15 | 2,287
Rheumatoid arthritis 14 | 1,191
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
invasive ductal carcinoma 14 | 2,951
pancreatic cancer 14 | 2,398
tuberculosis 14 | 2,010
Pick disease 13 | 1,894
astrocytoma 13 | 1,146
dermatomyositis 13 | 966
lung adenocarcinoma 13 | 2,716
Schizophrenia 12 | 1,160
diabetes mellitus 12 | 1,728
group 4 medulloblastoma 12 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
non-small cell lung cancer 12 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
acute myeloid leukemia 11 | 783
adult high grade glioma 11 | 3,801
Muscle hypotonia 10 | 571
colon cancer 10 | 1,478
juvenile dermatomyositis 10 | 1,187
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Small head 9 | 374
Spinocerebellar ataxia type 7 9 | 13
Waldenstrons macroglobulinemia 9 | 765
astrocytic glioma 9 | 2,597
ductal carcinoma in situ 9 | 1,745
lung carcinoma 9 | 2,843
spina bifida 9 | 1,074
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
Epilepsy 8 | 792
Seizures 8 | 596
Short stature 8 | 531
Acquired scoliosis 7 | 281
Adenoid Cystic Carcinoma 7 | 99
Carcinoma, Adenoid Cystic 7 | 99
Cognitive delay 7 | 608
Curvature of spine 7 | 282
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Neurodegenerative disease 7 | 414
acute quadriplegic myopathy 7 | 1,158
pediatric high grade glioma 7 | 1,064
Alzheimer's disease 6 | 658
Atrial Septal Defects 6 | 85
Blepharoptosis 6 | 231
Cryptorchidism 6 | 296
Endometrial cancer 6 | 311
Liver cancer 6 | 604
Low set ears 6 | 181
adrenocortical carcinoma 6 | 1,428
breast carcinoma 6 | 1,638
hepatocellular carcinoma 6 | 547
non primary Sjogren syndrome sicca 6 | 891
progressive supranuclear palsy 6 | 676
Bipolar Disorder 5 | 666
Breast Neoplasms 5 | 445
Broad flat nasal bridge 5 | 236
Byzanthine arch palate 5 | 194
Carcinoma, Squamous Cell 5 | 110
Congenital deafness 5 | 185
Deafness 5 | 198
Downward slant of palpebral fissure 5 | 158
Endometriosis 5 | 540
Feeding difficulties in infancy 5 | 175
Hearing Loss, Partial 5 | 185
Immune system cancer 5 | 140
Mood Disorders 5 | 184
Nasal bridge wide 5 | 236
Squamous cell carcinoma 5 | 129
Strabismus 5 | 270
Ventricular Septal Defects 5 | 119
cystic fibrosis 5 | 1,696
hearing impairment 5 | 199
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109

Tissue

Female tissues 115 | 17,400
Skin and soft tissues 115 | 17,230
Blood and immune system 114 | 16,909
Digestive Tract 114 | 17,369
Endocrine System 114 | 18,159
Liver and Pancreas 114 | 16,750
Male tissues 114 | 17,142
Nervous System 114 | 16,725
Urinary Tract 114 | 16,678
Respiratory system 113 | 16,393
Cardiovascular System 111 | 15,192

Target Family

Non-IDG 51 | 12,091
Epigenetic 31 | 242
Enzyme 22 | 4,145
Kinase 8 | 634
Transcription Factor 3 | 1,400
TF/Epigenetic 1 | 38

Compartment GO Term

Protein acetyltransferase comp... 116 | 116
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E1A-binding protein p400 EP400 Tbio Non-IDG -1.47248 27.6 69
Serine/threonine-protein kinase 3 STK3 Tchem Kinase -1.13339 11.3 303
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L TAF6L Tdark Enzyme 0.55 0.23 173
Protein Dr1 DR1 Tbio Non-IDG -2.51135 313.8 146
Inactive heparanase-2 HPSE2 Tbio Enzyme -2.52081 326.4 137
E3 ubiquitin-protein ligase MSL2 MSL2 Tbio Enzyme -1.78868 59.2 117
MRG/MORF4L-binding protein MRGBP Tbio Non-IDG -0.74186 5.72 147
Histone acetyltransferase KAT6B KAT6B Tbio Epigenetic -2.30232 201.0 58
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
N-alpha-acetyltransferase 15, NatA auxiliary subunit NAA15 Tbio Enzyme -2.09909 118.0 157