Development Level

Tbio 29 | 11,651
Tchem 6 | 1,388
Tclin 6 | 612
Tdark 5 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
increased grip strength 2 | 41
preweaning lethality, incomple... 2 | 499
abnormal hair growth 1 | 10
abnormal kidney morphology 1 | 65
abnormal snout morphology 1 | 23
decreased vertical activity 1 | 208
increased aggression 1 | 4
male infertility 1 | 123
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytosis 1 | 27

Disease

ovarian cancer 34 | 8,520
psoriasis 21 | 6,694
Multiple myeloma 20 | 1,332
Carcinoma 19 | 11,493
lung cancer 18 | 4,740
glioblastoma 17 | 5,792
osteosarcoma 14 | 7,950
Cancer 13 | 2,499
HIV Infections 13 | 102
Waldenstrons macroglobulinemia 11 | 765
dermatomyositis 9 | 966
ependymoma 9 | 4,679
medulloblastoma, large-cell 9 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
malignant mesothelioma 8 | 3,232
Breast cancer 7 | 3,578
astrocytic glioma 7 | 2,597
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
diabetes mellitus 6 | 1,728
group 3 medulloblastoma 6 | 4,104
non primary Sjogren syndrome sicca 6 | 891
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Astrocytoma, Pilocytic 5 | 3,081
Mantle cell lymphoma 5 | 23
Neurodegenerative disease 5 | 414
astrocytoma 5 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
tuberculosis 5 | 2,010
Liver Cirrhosis, Experimental 4 | 769
Pick disease 4 | 1,894
juvenile dermatomyositis 4 | 1,187
lung adenocarcinoma 4 | 2,716
primary Sjogren syndrome 4 | 735
subependymal giant cell astrocytoma 4 | 2,287
Candidiasis 3 | 55
Epidermolysis bullosa acquisita 3 | 10
Henoch-Schoenlein purpura 3 | 12
Major Depressive Disorder 3 | 301
Malaria 3 | 160
Ollier disease 3 | 18
Unipolar Depression 3 | 250
Vascular disease 3 | 319
active Crohn's disease 3 | 922
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
group 4 medulloblastoma 3 | 1,855
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
Animal Mammary Neoplasms 2 | 136
Autosomal dominant Robinow syndrome 1 2 | 15
Autosomal recessive predisposition 2 | 1,442
Esophageal Squamous Cell Carcinoma 2 | 77
JMP syndrome 2 | 2
Kidney cancer 2 | 2,613
Liver neoplasms 2 | 130
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Mood Disorders 2 | 184
Muscular atrophy 2 | 71
Osteoporosis 2 | 363
Squamous cell carcinoma of esophagus 2 | 77
acute myeloid leukemia 2 | 783
chronic kidney disease 2 | 90
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 459
substance-related disorder 2 | 162
Acne 1 | 52
Acute lymphoid leukemia 1 | 25
Anaplastic large T-cell systemic malignant lymphoma 1 | 10
Burkitt's lymphoma 1 | 15
Carcinoma of breast 1 | 11
Carcinoma of female breast 1 | 20
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Diffuse non-Hodgkin's lymphoma, large cell 1 | 12
Episcleritis 1 | 3
Exfoliation Syndrome 1 | 12
Follicular non-Hodgkin's lymphoma 1 | 17
Full lower lip 1 | 64
Hodgkin's disease 1 | 18
Hypertensive disorder 1 | 57
Hypertriglyceridemia result 1 | 37
Langerhans cell histiocytosis, disseminated 1 | 10
Malignant tumor of prostate 1 | 26
Malignant tumor of stomach 1 | 12
Malignant tumor of testis 1 | 11
Metastatic Breast Carcinoma 1 | 21
Mycosis fungoides 1 | 29
Non-Hodgkin's lymphoma 1 | 22
Prominent lower lip 1 | 64
Waterhouse-Friderichsen syndrome 1 | 11

Tissue

Endocrine System 44 | 18,159
Digestive Tract 43 | 17,369
Female tissues 43 | 17,400
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Respiratory system 43 | 16,393
Urinary Tract 43 | 16,678
Blood and immune system 42 | 16,909
Cardiovascular System 42 | 15,192
Liver and Pancreas 42 | 16,750
Skin and soft tissues 42 | 17,230

Target Family

Enzyme 29 | 4,145
Non-IDG 16 | 12,091
Transporter 1 | 473

Compartment GO Term

Proteasome core complex 46 | 46
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chymotrypsin-like protease CTRL-1 CTRL Tchem Enzyme -3.14577 1283.5 150
Ubiquitin carboxyl-terminal hydrolase isozyme L5 UCHL5 Tbio Enzyme -1.71687 51.9 225
Ubiquitin carboxyl-terminal hydrolase 14 USP14 Tbio Enzyme -1.85726 75.4 223
26S proteasome non-ATPase regulatory subunit 3 PSMD3 Tbio Enzyme -1.22269 15.9 168
Proteasome activator complex subunit 3 PSME3 Tbio Non-IDG -1.87037 83.7 245
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
26S proteasome regulatory subunit 8 PSMC5 Tbio Enzyme -1.70989 52.2 200
26S proteasome non-ATPase regulatory subunit 8 PSMD8 Tbio Enzyme -1.43676 24.7 100
Proteasome subunit alpha type-1 PSMA1 Tclin Enzyme -1.36375 17.4 235
Proteasome subunit beta type-3 PSMB3 Tdark Enzyme -0.57754 2.94 81