Development Level

Tbio 113 | 10,625
Tchem 67 | 1,890
Tclin 36 | 602
Tdark 6 | 7,003

IMPC Phenotype

preweaning lethality, complete... 10 | 633
preweaning lethality, incomple... 8 | 260
decreased lean body mass 5 | 195
abnormal behavior 4 | 226
decreased circulating insulin ... 3 | 75
decreased startle reflex 3 | 48
embryonic lethality prior to t... 3 | 187
increased mean corpuscular vol... 3 | 91
increased or absent threshold ... 3 | 128
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal retina morphology 2 | 100
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
decreased total body fat amoun... 2 | 186
enlarged epididymis 2 | 27
hypoactivity 2 | 89
increased body length 2 | 20
increased circulating alkaline... 2 | 119
increased grip strength 2 | 83
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
male infertility 2 | 62
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal motor learning 1 | 4
abnormal neural tube closure 1 | 37
abnormal response to new envir... 1 | 8
abnormal retinal inner nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spine curvature 1 | 7
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
absent startle reflex 1 | 15
decreased CD4-positive NK T ce... 1 | 4
decreased CD5-positive Ly6C-po... 1 | 4
decreased Ly6C-positive NK T c... 1 | 2
decreased NK T cell number 1 | 28
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased erythrocyte cell num... 1 | 43
decreased fluid intake 1 | 2
decreased food intake 1 | 6
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased memory-marker CD4-ne... 1 | 4
decreased monocyte cell number 1 | 28
decreased respiratory quotient 1 | 12
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
hydrops fetalis 1 | 22
hyperactivity 1 | 108
immune system phenotype 1 | 17
increased Ly6C-positive NK T c... 1 | 1
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating aspartat... 1 | 17
increased circulating choleste... 1 | 53
increased circulating triglyce... 1 | 24
increased effector memory CD8-... 1 | 14
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased heart rate 1 | 17
increased total body fat amoun... 1 | 57
microphthalmia 1 | 15
prolonged QRS complex duration 1 | 2
short tibia 1 | 82
shortened RR interval 1 | 19
small testis 1 | 37
sparse hair 1 | 6
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

ovarian cancer 147 | 8,491
Cancer 133 | 2,346
psoriasis 111 | 6,685
lung cancer 93 | 4,473
osteosarcoma 93 | 7,933
glioblastoma 91 | 5,572
diabetes mellitus 70 | 1,663
medulloblastoma, large-cell 68 | 6,234
Multiple myeloma 67 | 1,327
atypical teratoid / rhabdoid tumor 63 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 50 | 3,289
malignant mesothelioma 49 | 3,163
Breast cancer 48 | 3,098
oligodendroglioma 48 | 2,849
ulcerative colitis 47 | 2,087
Alzheimer's disease 45 | 644
pediatric high grade glioma 45 | 2,712
non-small cell lung cancer 43 | 2,798
pilocytic astrocytoma 43 | 3,086
Obesity 41 | 616
invasive ductal carcinoma 40 | 2,950
Mammary Neoplasms 39 | 410
astrocytoma 39 | 1,493
Kidney disease 38 | 397
Parkinson's disease 38 | 364
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,988
lung adenocarcinoma 38 | 2,714
primitive neuroectodermal tumor 38 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,956
tuberculosis 37 | 1,563
Vascular disease 36 | 281
pancreatic ductal adenocarcinoma liver metastasis 36 | 1,795
ependymoma 35 | 2,514
Prostatic Neoplasms 34 | 471
subependymal giant cell astrocytoma 34 | 2,287
Heart disease 33 | 279
astrocytic glioma 33 | 2,241
pancreatic cancer 33 | 2,300
Arthritis 32 | 248
Toxic encephalopathy 32 | 131
interstitial cystitis 32 | 2,299
lung carcinoma 32 | 2,844
Waldenstrons macroglobulinemia 31 | 764
pituitary cancer 31 | 1,972
group 4 medulloblastoma 30 | 1,875
Asthma 29 | 349
Hypertension 29 | 293
Liver carcinoma 29 | 217
Lung Neoplasms 29 | 171
Neurodegenerative disease 29 | 383
Rheumatoid Arthritis 29 | 1,170
medulloblastoma 29 | 1,524
Carcinoma 28 | 2,147
Lung disease 28 | 136
Cerebrovascular disease 27 | 231
Schizophrenia 27 | 503
colon cancer 27 | 1,475
Liver disease 26 | 219
Stomach Neoplasms 26 | 282
acute quadriplegic myopathy 26 | 1,157
adult high grade glioma 26 | 2,148
cystic fibrosis 26 | 1,670
breast carcinoma 25 | 1,614
posterior fossa group A ependymoma 25 | 1,511
Hyperglycemia 24 | 120
Inflammatory bowel disease 24 | 142
dermatomyositis 24 | 966
Atherosclerosis 23 | 275
HIV Infections 23 | 99
Osteoporosis 23 | 259
hepatocellular carcinoma 23 | 550
Colonic Neoplasms 22 | 126
Coronary artery disease 22 | 240
Hypertensive disease 22 | 193
Multiple Sclerosis 22 | 498
Pick disease 22 | 1,893
adrenocortical carcinoma 22 | 1,427
Adenoma 21 | 165
Endometriosis 21 | 535
Neuropathy 21 | 210
Reperfusion Injury 21 | 84
Hypersensitivity reaction type II disease 20 | 235
cutaneous lupus erythematosus 20 | 1,056
Amyotrophic Lateral Sclerosis 19 | 432
Brain disease 19 | 84
Diarrhea 19 | 155
Inflammation 19 | 109
Metabolic syndrome X 19 | 155
acute myeloid leukemia 19 | 785
ductal carcinoma in situ 19 | 1,745
Adenocarcinoma 18 | 115
Anemia 18 | 252
Brain Ischemia 18 | 87
Diabetes Mellitus, Experimental 18 | 106
Heart failure 18 | 80
Peripheral Neuropathy 18 | 303
Autistic Disorder 17 | 320
Neoplasm Metastasis 17 | 138
non-small cell lung carcinoma 17 | 413
sarcoidosis 17 | 368

Tissue

Digestive Tract 218 | 18,472
Endocrine System 218 | 18,511
Nervous System 218 | 18,560
Urinary Tract 218 | 18,443
Blood and immune system 217 | 17,994
Female tissues 217 | 18,646
Liver and Pancreas 217 | 18,135
Male tissues 216 | 17,968
Cardiovascular System 215 | 17,957
Respiratory system 215 | 17,483
Skin and soft tissues 214 | 18,114

Target Family

Non-IDG 104 | 11,969
Enzyme 77 | 4,146
Kinase 13 | 634
Transcription Factor 12 | 1,400
Nuclear Receptor 6 | 48
GPCR 5 | 408
Ion Channel 2 | 341
Transporter 2 | 473
Epigenetic 1 | 242

Compartment GO Term

Proteasome complex 222 | 222
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.25806 19000.3 3336
Protein YIPF1 YIPF1 Tbio Non-IDG -2.07470 81.5 69
E3 ubiquitin-protein ligase NEDD4-like NEDD4L Tbio Enzyme -2.50001 312.7 133
Von Hippel-Lindau disease tumor suppressor VHL Tchem Enzyme -2.45725 283.9 450
Bcl-2-like protein 11 BCL2L11 Tbio Non-IDG -3.14287 1340.6 903
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.75815 5706.6 1539
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.09050 11730.8 2241