Development Level

Tbio 113 | 10,625
Tchem 68 | 1,890
Tclin 36 | 602
Tdark 6 | 7,003

IMPC Term

preweaning lethality, complete... 10 | 633
preweaning lethality, incomple... 8 | 260
decreased lean body mass 5 | 195
abnormal behavior 4 | 226
decreased circulating insulin ... 3 | 75
decreased startle reflex 3 | 48
embryonic lethality prior to t... 3 | 187
increased mean corpuscular vol... 3 | 91
increased or absent threshold ... 3 | 128
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal retina morphology 2 | 100
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
decreased total body fat amoun... 2 | 186
enlarged epididymis 2 | 27
hypoactivity 2 | 89
increased body length 2 | 20
increased circulating alkaline... 2 | 119
increased grip strength 2 | 83
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
male infertility 2 | 62
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal motor learning 1 | 4
abnormal neural tube closure 1 | 37
abnormal response to new envir... 1 | 8
abnormal retinal inner nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spine curvature 1 | 7
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
absent startle reflex 1 | 15
decreased CD4-positive NK T ce... 1 | 4
decreased CD5-positive Ly6C-po... 1 | 4
decreased Ly6C-positive NK T c... 1 | 2
decreased NK T cell number 1 | 28
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased erythrocyte cell num... 1 | 43
decreased fluid intake 1 | 2
decreased food intake 1 | 6
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased memory-marker CD4-ne... 1 | 4
decreased monocyte cell number 1 | 28
decreased respiratory quotient 1 | 12
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
hydrops fetalis 1 | 22
hyperactivity 1 | 108
immune system phenotype 1 | 17
increased Ly6C-positive NK T c... 1 | 1
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating aspartat... 1 | 17
increased circulating choleste... 1 | 53
increased circulating triglyce... 1 | 24
increased effector memory CD8-... 1 | 14
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased heart rate 1 | 17
increased total body fat amoun... 1 | 57
microphthalmia 1 | 15
prolonged QRS complex duration 1 | 2
short tibia 1 | 82
shortened RR interval 1 | 19
small testis 1 | 37
sparse hair 1 | 6
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

ovarian cancer 148 | 8,492
Cancer 133 | 2,346
psoriasis 111 | 6,685
lung cancer 93 | 4,473
osteosarcoma 93 | 7,933
glioblastoma 91 | 5,572
diabetes mellitus 70 | 1,663
Multiple myeloma 68 | 1,328
medulloblastoma, large-cell 68 | 6,234
atypical teratoid / rhabdoid tumor 63 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 50 | 3,289
Breast cancer 49 | 3,099
malignant mesothelioma 49 | 3,163
oligodendroglioma 48 | 2,849
ulcerative colitis 47 | 2,087
Alzheimer's disease 45 | 644
pediatric high grade glioma 45 | 2,712
non-small cell lung cancer 43 | 2,798
pilocytic astrocytoma 43 | 3,086
Obesity 41 | 616
invasive ductal carcinoma 40 | 2,950
Mammary Neoplasms 39 | 410
astrocytoma 39 | 1,493
Kidney disease 38 | 397
Parkinson's disease 38 | 364
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,988
lung adenocarcinoma 38 | 2,714
primitive neuroectodermal tumor 38 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,956
tuberculosis 37 | 1,563
Vascular disease 36 | 281
pancreatic ductal adenocarcinoma liver metastasis 36 | 1,795
ependymoma 35 | 2,514
Prostatic Neoplasms 34 | 471
subependymal giant cell astrocytoma 34 | 2,287
Heart disease 33 | 279
astrocytic glioma 33 | 2,241
pancreatic cancer 33 | 2,300
Arthritis 32 | 248
Toxic encephalopathy 32 | 131
Waldenstrons macroglobulinemia 32 | 765
interstitial cystitis 32 | 2,299
lung carcinoma 32 | 2,844
pituitary cancer 31 | 1,972
Rheumatoid Arthritis 30 | 1,171
group 4 medulloblastoma 30 | 1,875
Asthma 29 | 349
Hypertension 29 | 293
Liver carcinoma 29 | 217
Lung Neoplasms 29 | 171
Neurodegenerative disease 29 | 383
medulloblastoma 29 | 1,524
Carcinoma 28 | 2,147
Lung disease 28 | 136
Cerebrovascular disease 27 | 231
Schizophrenia 27 | 503
colon cancer 27 | 1,475
Liver disease 26 | 219
Stomach Neoplasms 26 | 282
acute quadriplegic myopathy 26 | 1,157
adult high grade glioma 26 | 2,148
cystic fibrosis 26 | 1,670
breast carcinoma 25 | 1,614
dermatomyositis 25 | 967
posterior fossa group A ependymoma 25 | 1,511
HIV Infections 24 | 100
Hyperglycemia 24 | 120
Inflammatory bowel disease 24 | 142
Atherosclerosis 23 | 275
Osteoporosis 23 | 259
hepatocellular carcinoma 23 | 550
Colonic Neoplasms 22 | 126
Coronary artery disease 22 | 240
Hypertensive disease 22 | 193
Multiple Sclerosis 22 | 498
Pick disease 22 | 1,893
adrenocortical carcinoma 22 | 1,427
Adenoma 21 | 165
Endometriosis 21 | 535
Neuropathy 21 | 210
Reperfusion Injury 21 | 84
Hypersensitivity reaction type II disease 20 | 235
cutaneous lupus erythematosus 20 | 1,056
Amyotrophic Lateral Sclerosis 19 | 432
Brain disease 19 | 84
Diarrhea 19 | 155
Inflammation 19 | 109
Metabolic syndrome X 19 | 155
acute myeloid leukemia 19 | 785
ductal carcinoma in situ 19 | 1,745
Adenocarcinoma 18 | 115
Anemia 18 | 252
Brain Ischemia 18 | 87
Diabetes Mellitus, Experimental 18 | 106
Heart failure 18 | 80
Peripheral Neuropathy 18 | 303
Autistic Disorder 17 | 320
Neoplasm Metastasis 17 | 138
non-small cell lung carcinoma 17 | 413
sarcoidosis 17 | 368

Tissue

Digestive Tract 219 | 18,473
Endocrine System 219 | 18,512
Nervous System 219 | 18,561
Urinary Tract 219 | 18,444
Blood and immune system 218 | 17,995
Female tissues 218 | 18,647
Liver and Pancreas 218 | 18,136
Male tissues 217 | 17,969
Cardiovascular System 216 | 17,958
Respiratory system 216 | 17,484
Skin and soft tissues 215 | 18,115

Target Family

Non-IDG 104 | 11,969
Enzyme 78 | 4,146
Kinase 13 | 634
Transcription Factor 12 | 1,400
Nuclear Receptor 6 | 48
GPCR 5 | 408
Ion Channel 2 | 341
Transporter 2 | 473
Epigenetic 1 | 242

Compartment GO Term

Proteasome complex 223 | 223
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasomal ATPase-associated factor 1 PAAF1 Tbio Enzyme -1.63557 41.8 63
Metabotropic glutamate receptor 4 GRM4 Tchem GPCR -2.32485 207.4 140
Sequestosome-1 SQSTM1 Tbio Non-IDG -2.71345 536.6 655
UV excision repair protein RAD23 homolog A RAD23A Tbio Non-IDG -1.57282 35.7 282
UV excision repair protein RAD23 homolog B RAD23B Tbio Non-IDG -1.98667 88.6 284
Caspase-8 CASP8 Tchem Enzyme -3.51864 2954.7 930
Protein DDI1 homolog 1 DDI1 Tdark Non-IDG -1.36953 25.5 39
Ubiquilin-2 UBQLN2 Tbio Non-IDG -1.88154 75.0 144
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.12726 13094.7 961
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.09050 11730.8 2241