Development Level

Tbio 6 | 11,445
Tchem 3 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

abnormal kidney morphology 1 | 65
decreased vertical activity 1 | 208
increased aggression 1 | 4
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

ovarian cancer 9 | 8,520
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
osteosarcoma 6 | 7,950
psoriasis 6 | 6,694
Carcinoma 5 | 11,493
HIV Infections 5 | 102
dermatomyositis 5 | 966
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
Liver Cirrhosis, Experimental 4 | 769
Multiple myeloma 4 | 1,332
astrocytoma 4 | 1,146
ependymoma 4 | 4,679
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
group 4 medulloblastoma 3 | 1,855
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
non-small cell lung cancer 3 | 2,890
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Breast cancer 2 | 3,578
Esophageal Squamous Cell Carcinoma 2 | 77
JMP syndrome 2 | 2
Kidney cancer 2 | 2,613
Squamous cell carcinoma of esophagus 2 | 77
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
chronic kidney disease 2 | 90
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
primary Sjogren syndrome 2 | 735
Animal Mammary Neoplasms 1 | 136
Ankylosing spondylitis 1 | 140
Arthralgia 1 | 90
Arthrogryposis 1 | 54
Barrett's esophagus 1 | 182
Bone pain 1 | 42
COPD 1 | 118
Cardiomegaly 1 | 116
Congenital clubfoot 1 | 109
Congestive heart failure 1 | 113
Conjunctivitis 1 | 53
Elevated hepatic transaminases 1 | 81
Episcleritis 1 | 3
Erythema 1 | 58
Exanthema 1 | 43
Flexion contracture of proximal interphalangeal joint 1 | 75
Flushing 1 | 60
Full lower lip 1 | 64
Generalized osteopenia 1 | 99
Globe of eye large 1 | 20
Heart failure 1 | 162
Hyperhidrosis disorder 1 | 81
Hyperpigmentation 1 | 37
Hyperplasia of nose 1 | 23
Hypertriglyceridemia result 1 | 37
Hypertrophy of nose 1 | 23
Increased sweating 1 | 81
Intermittent fever 1 | 15
Iron-Refractory Iron Deficiency Anemia 1 | 15
Joint stiffness 1 | 84
Large auricle 1 | 87
Large dysplastic ears 1 | 87
Large nose 1 | 23
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large protruding ears 1 | 87
Large, floppy ears 1 | 87
Liver function test increased 1 | 81
Lymphadenopathy 1 | 62
Macroglossia 1 | 65
Macrotia 1 | 87
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Muscle Weakness 1 | 170
Muscular atrophy 1 | 71
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Osteopenia 1 | 99
Periodontal disease 1 | 40
Prominent lower lip 1 | 64
Right atrial isomerism 1 | 29
Severe acute respiratory syndrome 1 | 27
Skeletal muscle atrophy 1 | 139
Subclinical abnormal liver function tests 1 | 81
Sweating 1 | 81
Waterhouse-Friderichsen syndrome 1 | 11
hand, foot and mouth disease 1 | 13
muscle degeneration 1 | 139
sarcoidosis 1 | 370
severe Alzheimer's disease 1 | 47

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 4 | 4,145

Compartment GO Term

Proteasome activator complex 12 | 12
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Sestrin-1 SESN1 Tbio Non-IDG -1.95681 82.0 172
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Proteasome-associated protein ECM29 homolog ECPAS Tbio Non-IDG -1.23024 16.0 35
Proteasome activator complex subunit 1 PSME1 Tbio Non-IDG -1.72313 55.9 233
Proteasome subunit beta type-8 PSMB8 Tclin Enzyme -2.43601 278.6 295
ER membrane protein complex subunit 9 EMC9 Tdark Non-IDG 0.85 0.10 24
Chymotrypsin-like protease CTRL-1 CTRL Tchem Enzyme -3.14577 1283.5 150
Proteasome activator complex subunit 3 PSME3 Tbio Non-IDG -1.87037 83.7 245