Development Level

Tbio 25 | 11,445
Tchem 13 | 1,598
Tclin 4 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased circulating bilirubi... 2 | 19
embryonic growth retardation 2 | 106
abnormal eye morphology 1 | 68
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
decreased anxiety-related resp... 1 | 12
decreased circulating creatini... 1 | 39
decreased heart rate 1 | 18
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased mean corpuscular hem... 1 | 96
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged ST segment 1 | 36

Disease

Carcinoma 32 | 11,493
Cancer 29 | 2,499
psoriasis 26 | 6,694
ovarian cancer 18 | 8,520
cystic fibrosis 17 | 1,696
lung cancer 17 | 4,740
osteosarcoma 16 | 7,950
interstitial cystitis 15 | 2,312
lung carcinoma 15 | 2,843
medulloblastoma, large-cell 15 | 6,241
Atopic dermatitis 14 | 952
non-small cell lung cancer 14 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Autosomal recessive predisposition 12 | 1,442
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
lung adenocarcinoma 12 | 2,716
pancreatic cancer 12 | 2,398
cutaneous lupus erythematosus 11 | 1,057
ependymoma 11 | 4,679
glioblastoma 11 | 5,792
group 3 medulloblastoma 11 | 4,104
invasive ductal carcinoma 11 | 2,951
malignant mesothelioma 11 | 3,232
Cerebrovascular disease 10 | 238
Kidney disease 10 | 430
diabetes mellitus 10 | 1,728
nasopharyngeal carcinoma 10 | 1,058
tuberculosis 10 | 2,010
ulcerative colitis 10 | 1,819
Astrocytoma, Pilocytic 9 | 3,081
spina bifida 9 | 1,074
Coronary artery disease 8 | 268
Disseminated intravascular coagulation 8 | 38
Hypertension 8 | 396
Prostatic Neoplasms 8 | 495
Pulmonary embolism 8 | 55
adult high grade glioma 8 | 3,801
atypical teratoid / rhabdoid tumor 8 | 5,112
Alzheimer's disease 7 | 658
Breast cancer 7 | 3,578
Hypersensitivity reaction type II disease 7 | 253
Liver Cirrhosis, Experimental 7 | 769
Liver disease 7 | 237
Periodontal disease 7 | 40
Thrombophilia 7 | 38
colon cancer 7 | 1,478
gastric carcinoma 7 | 807
Atherosclerosis 6 | 291
Chronic obstructive pulmonary disease 6 | 184
Heart disease 6 | 306
Lung disease 6 | 142
Schizophrenia 6 | 1,160
breast carcinoma 6 | 1,638
ductal carcinoma in situ 6 | 1,745
esophageal adenocarcinoma 6 | 737
juvenile dermatomyositis 6 | 1,187
subependymal giant cell astrocytoma 6 | 2,287
Antithrombin III deficiency 5 | 14
Arthritis 5 | 290
Breast Neoplasms 5 | 445
Dementia 5 | 175
Hepatic veno-occlusive disease 5 | 16
Hyperhomocysteinemia 5 | 37
Mammary Neoplasms 5 | 425
Obesity 5 | 678
Pancreatitis 5 | 123
Peripheral vascular disease 5 | 87
Protein C deficiency 5 | 19
Thrombocytopenia 5 | 197
Thrombosis 5 | 46
Vascular disease 5 | 319
Venous Thrombosis 5 | 47
active ulcerative colitis 5 | 764
fibroadenoma 5 | 559
nephrosclerosis 5 | 333
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
primitive neuroectodermal tumor 5 | 3,035
Alpha 1-antitrypsin deficiency 4 | 11
Angioedema 4 | 38
Asthma 4 | 385
Bipolar Disorder 4 | 666
Blood protein disease 4 | 11
Brain Ischemia 4 | 110
Brain disease 4 | 96
Kidney cancer 4 | 2,613
Liver Cirrhosis 4 | 181
Melanoma 4 | 711
Menorrhagia 4 | 25
Neoplasm Metastasis 4 | 168
Neurodegenerative disease 4 | 414
Stomach Neoplasms 4 | 300
astrocytic glioma 4 | 2,597
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
interstitial lung disease 4 | 298
oligodendroglioma 4 | 2,850
periodontitis 4 | 293
pituitary cancer 4 | 1,972

Tissue

Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Male tissues 43 | 17,142
Skin and soft tissues 43 | 17,230
Blood and immune system 42 | 16,909
Liver and Pancreas 42 | 16,750
Urinary Tract 41 | 16,678
Nervous System 40 | 16,725
Respiratory system 40 | 16,393
Cardiovascular System 36 | 15,192

Target Family

Non-IDG 24 | 12,091
Enzyme 20 | 4,145

Compartment GO Term

Protease inhibitor complex 44 | 44
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Leukocyte elastase inhibitor SERPINB1 Tbio Enzyme -2.55345 336.3 370
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Alpha-1-antichymotrypsin SERPINA3 Tbio Non-IDG -2.94780 812.7 276
Protein AMBP AMBP Tbio Non-IDG -2.61031 420.1 396
Serpin B10 SERPINB10 Tbio Non-IDG -2.02571 100.6 101
Kunitz-type protease inhibitor 1 SPINT1 Tbio Enzyme -1.88525 86.6 275
Prostasin PRSS8 Tchem Enzyme -1.99808 113.0 199
Caspase recruitment domain-containing protein 16 CARD16 Tbio Enzyme -2.61398 389.0 124
Neutrophil elastase ELANE Tclin Enzyme -3.61753 3958.4 411