Development Level

Tbio 173 | 11,445
Tchem 36 | 1,598
Tclin 35 | 613
Tdark 23 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 13 | 499
abnormal behavior 12 | 298
decreased bone mineral content 9 | 151
decreased total body fat amoun... 8 | 207
hyperactivity 8 | 148
increased circulating sodium l... 8 | 71
increased total body fat amoun... 8 | 134
decreased fasted circulating g... 6 | 65
increased circulating chloride... 6 | 41
increased lean body mass 6 | 172
decreased grip strength 5 | 116
decreased lean body mass 5 | 135
impaired glucose tolerance 5 | 75
short tibia 5 | 97
tremors 5 | 39
abnormal behavioral response t... 4 | 66
abnormal bone structure 4 | 187
decreased bone mineral density 4 | 126
decreased circulating HDL chol... 4 | 68
decreased circulating choleste... 4 | 93
decreased lymphocyte cell numb... 4 | 83
decreased vertical activity 4 | 208
embryonic lethality prior to t... 4 | 278
hypoactivity 4 | 132
increased bone mineral content 4 | 108
increased circulating alkaline... 4 | 122
increased mean corpuscular vol... 4 | 92
prolonged QT interval 4 | 38
prolonged ST segment 4 | 36
abnormal eye morphology 3 | 68
abnormal gait 3 | 69
abnormal sleep behavior 3 | 70
abnormal testis morphology 3 | 43
decreased body length 3 | 101
decreased circulating alkaline... 3 | 46
decreased circulating serum al... 3 | 82
decreased neutrophil cell numb... 3 | 42
embryonic lethality prior to o... 3 | 239
improved glucose tolerance 3 | 79
increased or absent threshold ... 3 | 101
small testis 3 | 58
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal locomotor behavior 2 | 24
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal sensory capabilities-... 2 | 8
convulsive seizures 2 | 13
decreased circulating LDL chol... 2 | 38
decreased circulating insulin ... 2 | 76
decreased circulating total pr... 2 | 49
decreased mean corpuscular hem... 2 | 50
decreased prepulse inhibition 2 | 82
decreased pulmonary respirator... 2 | 5
decreased startle reflex 2 | 75
edema 2 | 59
enlarged heart 2 | 210
enlarged stomach 2 | 2
increased blood urea nitrogen ... 2 | 48
increased circulating amylase ... 2 | 25
increased circulating iron lev... 2 | 30
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased lymphocyte cell numb... 2 | 32
increased monocyte cell number 2 | 63
increased prepulse inhibition 2 | 32
increased red blood cell distr... 2 | 34
limb grasping 2 | 41
persistence of hyaloid vascula... 2 | 33
prenatal lethality 2 | 28
small spleen 2 | 19
small thymus 2 | 16
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal optic disc morphology 1 | 10
abnormal spleen morphology 1 | 55
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating creatine... 1 | 4
decreased circulating magnesiu... 1 | 13
decreased circulating triglyce... 1 | 79
enlarged urinary bladder 1 | 8
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased mean platelet volume 1 | 45
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 186 | 11,493
glioblastoma 149 | 5,792
medulloblastoma, large-cell 146 | 6,241
ependymoma 142 | 4,679
atypical teratoid / rhabdoid tumor 133 | 5,112
adult high grade glioma 125 | 3,801
Astrocytoma, Pilocytic 116 | 3,081
oligodendroglioma 109 | 2,850
osteosarcoma 109 | 7,950
group 3 medulloblastoma 106 | 4,104
ovarian cancer 104 | 8,520
psoriasis 98 | 6,694
astrocytic glioma 95 | 2,597
primitive neuroectodermal tumor 95 | 3,035
Schizophrenia 92 | 1,160
Pick disease 80 | 1,894
lung carcinoma 74 | 2,843
lung cancer 65 | 4,740
Epilepsy 64 | 792
Bipolar Disorder 63 | 666
subependymal giant cell astrocytoma 59 | 2,287
Alzheimer's disease 55 | 658
Depressive disorder 55 | 409
Kidney cancer 54 | 2,613
Mental Depression 53 | 333
malignant mesothelioma 53 | 3,232
Alcoholic Intoxication, Chronic 50 | 289
Parkinson's disease 50 | 392
Breast cancer 42 | 3,578
Cancer 42 | 2,499
pituitary cancer 42 | 1,972
Seizures 40 | 596
diabetes mellitus 39 | 1,728
Intellectual disability 37 | 1,016
Major Depressive Disorder 37 | 301
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,291
invasive ductal carcinoma 35 | 2,951
non-small cell lung cancer 35 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,955
Toxic encephalopathy 33 | 141
group 4 medulloblastoma 33 | 1,855
Neurodegenerative disease 32 | 414
Unipolar Depression 32 | 250
Autistic Disorder 30 | 364
Mood Disorders 30 | 184
interstitial cystitis 30 | 2,312
Obesity 29 | 678
astrocytoma 29 | 1,146
lung adenocarcinoma 29 | 2,716
Autosomal recessive predisposition 28 | 1,442
Hypertension 28 | 396
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,989
tuberculosis 28 | 2,010
Pain agnosia 27 | 104
Cocaine-Related Disorders 26 | 92
Liver cancer 26 | 604
Alcohol dependence 24 | 107
Attention deficit hyperactivity disorder 23 | 278
colon cancer 23 | 1,478
pancreatic cancer 23 | 2,398
Pain 22 | 103
ductal carcinoma in situ 22 | 1,745
Dementia 21 | 175
Cerebrovascular disease 20 | 238
Down syndrome 20 | 499
Huntington's disease 20 | 76
Migraine 20 | 83
cystic fibrosis 20 | 1,696
Amyotrophic lateral sclerosis 19 | 451
Neuropathy 19 | 261
ulcerative colitis 19 | 1,819
Rheumatoid arthritis 18 | 1,191
Dysarthria 17 | 192
Substance abuse 17 | 59
Tetanus 17 | 68
pediatric high grade glioma 17 | 1,064
Cognitive delay 16 | 608
Constipation 16 | 181
Diarrhea 16 | 253
Global developmental delay 16 | 608
Hyperalgesia 16 | 83
Mental and motor retardation 16 | 608
aldosterone-producing adenoma 16 | 665
Brain disease 15 | 96
Dull intelligence 15 | 645
Low intelligence 15 | 645
Melanoma 15 | 711
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Multiple Sclerosis 15 | 540
Poor school performance 15 | 645
Asthma 14 | 385
Cocaine Dependence 14 | 51
Irritable bowel syndrome 14 | 60
Multiple myeloma 14 | 1,332
adrenocortical carcinoma 14 | 1,428
Cerebellar Ataxia 13 | 304
Dystonia 13 | 164
breast carcinoma 13 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962

Tissue

Endocrine System 259 | 18,159
Female tissues 250 | 17,400
Digestive Tract 249 | 17,369
Nervous System 249 | 16,725
Skin and soft tissues 244 | 17,230
Male tissues 242 | 17,142
Liver and Pancreas 239 | 16,750
Urinary Tract 229 | 16,678
Blood and immune system 225 | 16,909
Respiratory system 225 | 16,393
Cardiovascular System 201 | 15,192

Target Family

Non-IDG 165 | 12,091
Enzyme 34 | 4,145
Ion Channel 20 | 344
Transporter 18 | 473
GPCR 16 | 408
Kinase 8 | 634
oGPCR 4 | 421
Epigenetic 2 | 242

Compartment GO Term

Presynapse 267 | 267
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.81752 661.7 128
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Ras-related protein Rab-40C RAB40C Tbio Non-IDG -0.89913 7.57 111
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
Putative synaptogyrin-2 like protein N/A Tdark Non-IDG -0.69433 7.83 0
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304