Development Level

Tbio 30 | 11,445
Tdark 5 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal vitreous body morphol... 1 | 10
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
thrombocytosis 1 | 27

Disease

Carcinoma 26 | 11,493
ovarian cancer 26 | 8,520
medulloblastoma, large-cell 17 | 6,241
psoriasis 17 | 6,694
osteosarcoma 16 | 7,950
lung cancer 13 | 4,740
glioblastoma 12 | 5,792
Multiple myeloma 11 | 1,332
atypical teratoid / rhabdoid tumor 11 | 5,112
oligodendroglioma 10 | 2,850
Pick disease 9 | 1,894
ependymoma 9 | 4,679
Kidney cancer 8 | 2,613
Waldenstrons macroglobulinemia 8 | 765
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
malignant mesothelioma 8 | 3,232
Breast cancer 7 | 3,578
astrocytoma 7 | 1,146
dermatomyositis 7 | 966
group 3 medulloblastoma 7 | 4,104
primitive neuroectodermal tumor 7 | 3,035
acute quadriplegic myopathy 6 | 1,158
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
juvenile dermatomyositis 5 | 1,187
progressive supranuclear palsy 5 | 676
group 4 medulloblastoma 4 | 1,855
pancreatic cancer 4 | 2,398
subependymal giant cell astrocytoma 4 | 2,287
Absent auditory canals 3 | 23
Absent external auditory canals 3 | 23
Atresia of the external auditory canal 3 | 23
Atretic auditory canal 3 | 23
Cleft Palate 3 | 271
Conductive hearing loss 3 | 123
Gaucher disease type 1 3 | 180
Hypoplastic mandible condyle 3 | 275
Hypotrophic malar bone 3 | 129
Low set ears 3 | 181
Malar flattening 3 | 129
Mandibular hypoplasia 3 | 275
Melanoma 3 | 711
Micrognathism 3 | 275
Mixed connective tissue disease 3 | 16
Short stature 3 | 531
Small head 3 | 374
Uranostaphyloschisis 3 | 167
interstitial lung disease 3 | 298
non-small cell lung cancer 3 | 2,890
relapsing-remitting multiple sclerosis 3 | 18
sonic hedgehog group medulloblastoma 3 | 467
Acquired scoliosis 2 | 281
Amyotrophic lateral sclerosis 2 | 451
Autosomal recessive predisposition 2 | 1,442
Congenital Epicanthus 2 | 177
Congenital small ears 2 | 48
Curvature of spine 2 | 282
Decreased projection of maxilla 2 | 66
Decreased projection of midface 2 | 105
Deficiency of upper jaw bones 2 | 66
Delayed speech and language development 2 | 112
Downward slant of palpebral fissure 2 | 158
Dull intelligence 2 | 645
Epilepsy 2 | 792
Feeding difficulties 2 | 127
HIV Infections 2 | 102
Hypoplasia of the maxilla 2 | 66
Hypotrophic maxilla 2 | 66
Hypotrophic midface 2 | 105
Intellectual disability 2 | 1,016
Language Delay 2 | 112
Low intelligence 2 | 645
Lupus erythematosus 2 | 57
Maxillary retrognathia 2 | 66
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Midface retrusion 2 | 105
Muscular atrophy 2 | 71
Nager acrofacial dysostosis 2 | 21
Poor school performance 2 | 645
Posteriorly rotated ear 2 | 61
Radioulnar synostosis 2 | 35
Retrusion of upper jaw bones 2 | 66
Rheumatoid arthritis 2 | 1,191
Small midface 2 | 105
Speech Delay 2 | 112
Speech impairment 2 | 112
Systemic lupus erythematosus 2 | 194
Treacher Collins syndrome 2 | 27
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
pediatric high grade glioma 2 | 1,064
tuberculosis 2 | 2,010

Tissue

Cardiovascular System 36 | 15,192
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Blood and immune system 35 | 16,909
Respiratory system 35 | 16,393

Target Family

Non-IDG 29 | 12,091
Enzyme 4 | 4,145
Epigenetic 2 | 242
Kinase 2 | 634

Compartment GO Term

Prespliceosome 37 | 37
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Splicing factor 3B subunit 2 SF3B2 Tbio Non-IDG -1.32229 20.7 163
Pre-mRNA-splicing factor SYF1 XAB2 Tbio Non-IDG -1.02890 12.5 247
Spliceosome RNA helicase DDX39B DDX39B Tbio Enzyme -1.74494 60.6 182
Small nuclear ribonucleoprotein G SNRPG Tdark Non-IDG 0.12 1.33 104
Crooked neck-like protein 1 CRNKL1 Tbio Non-IDG -0.94007 9.12 48
Small nuclear ribonucleoprotein Sm D3 SNRPD3 Tbio Non-IDG -1.64561 38.0 165
Small nuclear ribonucleoprotein Sm D1 SNRPD1 Tbio Non-IDG -2.41573 241.5 105
Luc7-like protein 3 LUC7L3 Tbio Non-IDG -1.55004 34.3 53
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 DHX38 Tbio Enzyme -1.62527 42.6 88
Splicing factor 3B subunit 4 SF3B4 Tbio Non-IDG -1.44416 28.7 222