Development Level

Tbio 83 | 11,651
Tdark 24 | 6,593
Tchem 3 | 1,388

Collection

RFA-RM-18-021 4 | 328
Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to o... 3 | 239
abnormal coat-hair pigmentatio... 2 | 64
abnormal behavior 1 | 298
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal spine curvature 1 | 9
cataract 1 | 92
decreased NK cell number 1 | 2
decreased body length 1 | 101
decreased body weight 1 | 161
decreased coping response 1 | 8
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
fusion of vertebral arches 1 | 7
hydrometra 1 | 53
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased mean platelet volume 1 | 45
kyphosis 1 | 5
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23

Disease

Carcinoma 70 | 11,493
ovarian cancer 63 | 8,520
lung cancer 43 | 4,740
osteosarcoma 40 | 7,950
group 3 medulloblastoma 34 | 4,104
medulloblastoma, large-cell 32 | 6,241
psoriasis 26 | 6,694
colon cancer 23 | 1,478
glioblastoma 23 | 5,792
Multiple myeloma 18 | 1,332
diabetes mellitus 18 | 1,728
acute quadriplegic myopathy 17 | 1,158
atypical teratoid / rhabdoid tumor 15 | 5,112
Waldenstrons macroglobulinemia 12 | 765
Kidney cancer 11 | 2,613
Diamond-Blackfan anemia 10 | 31
ependymoma 10 | 4,679
malignant mesothelioma 10 | 3,232
non-small cell lung cancer 10 | 2,890
adult high grade glioma 9 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
pediatric high grade glioma 9 | 1,064
Abnormality of the urinary system 8 | 21
Adenocarcinoma of lung 8 | 142
Anemia 8 | 365
Anemia, Diamond-Blackfan 8 | 16
Anemia, Macrocytic 8 | 18
Cardiac Arrhythmia 8 | 103
Cardiac conduction abnormalities 8 | 78
Cleft Palate 8 | 271
Conduction disorder of the heart 8 | 79
Delayed Puberty 8 | 97
Disease Models, Animal 8 | 155
EKG abnormalities 8 | 78
Electrocardiogram abnormal 8 | 81
Electrocardiogram change 8 | 78
Fatigue 8 | 182
Hand deformities 8 | 32
Intermittent migraine headaches 8 | 68
Migraine Disorders 8 | 76
Pallor 8 | 40
Uranostaphyloschisis 8 | 167
dermatomyositis 8 | 966
genital abnormal 8 | 17
invasive ductal carcinoma 8 | 2,951
non primary Sjogren syndrome sicca 8 | 891
primitive neuroectodermal tumor 8 | 3,035
reproductive system abnormality 8 | 17
Breast cancer 7 | 3,578
Cancer 7 | 2,499
Stomach Neoplasms 7 | 300
Bowen-Conradi syndrome 6 | 16
Disease Progression 6 | 136
juvenile dermatomyositis 6 | 1,187
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
oligodendroglioma 5 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
sonic hedgehog group medulloblastoma 5 | 467
tuberculosis and treatment for 6 months 5 | 409
Astrocytoma, Pilocytic 4 | 3,081
Intellectual disability 4 | 1,016
Pick disease 4 | 1,894
Shwachman-Diamond syndrome 4 | 17
acute myeloid leukemia 4 | 783
astrocytoma 4 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung adenocarcinoma 4 | 2,716
mucosa-associated lymphoid tissue lymphoma 4 | 484
pancreatic cancer 4 | 2,398
subependymal giant cell astrocytoma 4 | 2,287
Autosomal recessive predisposition 3 | 1,442
Breast Neoplasms 3 | 445
Cleft Lip 3 | 141
Liver Cirrhosis 3 | 181
Mammary Neoplasms 3 | 425
Mean cell volume increased 3 | 5
Neurodegenerative disease 3 | 414
Obesity 3 | 678
Reticulocytopenia 3 | 10
Short stature 3 | 531
Treacher Collins syndrome 3 | 27
atypical teratoid/rhabdoid tumor 3 | 357
gastric carcinoma 3 | 807
hepatocellular carcinoma 3 | 547
Atherosclerosis 2 | 291
Cerebrovascular disease 2 | 238
Endometrial cancer 2 | 311
Hemoglobin low 2 | 124
Hypertension 2 | 396
Infantile onset 2 | 238
Liver cancer 2 | 604
Orofacial cleft 2 | 54
active Crohn's disease 2 | 922
breast carcinoma 2 | 1,638
hereditary spastic paraplegia 2 | 318
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
posterior fossa group B ependymoma 2 | 416
spina bifida 2 | 1,074

Tissue

Blood and immune system 109 | 16,909
Cardiovascular System 109 | 15,192
Digestive Tract 109 | 17,369
Endocrine System 109 | 18,159
Female tissues 109 | 17,400
Liver and Pancreas 109 | 16,750
Male tissues 109 | 17,142
Nervous System 109 | 16,725
Respiratory system 109 | 16,393
Skin and soft tissues 109 | 17,230
Urinary Tract 109 | 16,678

Target Family

Non-IDG 96 | 12,091
Enzyme 9 | 4,145
Kinase 3 | 634
GPCR 1 | 408
Transcription Factor 1 | 1,400

Compartment GO Term

Preribosome 110 | 110
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of SWI4 1 homolog PPAN-P2RY11 Tbio Non-IDG -2.66392 881.0 97
Periodic tryptophan protein 1 homolog PWP1 Tbio Non-IDG -0.80806 7.04 62
WD repeat-containing protein 18 WDR18 Tbio Non-IDG -1.69131 43.0 108
Testis-expressed protein 10 TEX10 Tdark Non-IDG -0.59960 4.28 21
Thioredoxin-like protein 4B TXNL4B Tbio Non-IDG -2.20773 154.6 44
mRNA turnover protein 4 homolog MRTO4 Tbio Non-IDG -1.05881 10.9 175
Angio-associated migratory cell protein AAMP Tbio Non-IDG -1.47842 30.9 123
Nucleolar complex protein 2 homolog NOC2L Tbio Non-IDG -2.54468 350.1 85
Probable rRNA-processing protein EBP2 EBNA1BP2 Tbio Non-IDG -1.54043 34.9 87
U3 small nucleolar ribonucleoprotein protein IMP3 IMP3 Tbio Non-IDG -0.34242 1.83 146