Development Level

Tbio 33 | 11,445
Tdark 10 | 6,588
Tchem 2 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to t... 3 | 278
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased fasted circulating g... 2 | 76
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal neural tube morpholog... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased leukocyte cell numbe... 1 | 73
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 29 | 8,520
Carcinoma 26 | 11,493
osteosarcoma 17 | 7,950
psoriasis 13 | 6,694
group 3 medulloblastoma 12 | 4,104
glioblastoma 11 | 5,792
lung cancer 10 | 4,740
medulloblastoma, large-cell 10 | 6,241
ependymoma 8 | 4,679
oligodendroglioma 8 | 2,850
Intellectual disability 7 | 1,016
Multiple myeloma 7 | 1,332
atypical teratoid / rhabdoid tumor 7 | 5,112
Kidney cancer 6 | 2,613
acute quadriplegic myopathy 6 | 1,158
Congenital hypoplasia of penis 5 | 176
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Retinitis Pigmentosa 5 | 226
dermatomyositis 5 | 966
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
primitive neuroectodermal tumor 5 | 3,035
Abnormality of retinal pigmentation 4 | 111
Abnormality of the retinal vasculature 4 | 59
Anteverted nostril 4 | 191
Atypical scarring of skin 4 | 62
Blind Vision 4 | 111
Blindness, Legal 4 | 110
Broad flat nasal bridge 4 | 236
Cataract 4 | 297
Conductive hearing loss 4 | 123
Congenital anomaly of testis 4 | 52
Electroretinogram abnormal 4 | 95
Glaucoma 4 | 239
Hyperinsulinism 4 | 133
Hypogonadism 4 | 173
Keratoconus 4 | 113
Lens Opacities 4 | 231
Nasal bridge wide 4 | 236
Night blindness, progressive 4 | 51
Nystagmus 4 | 317
Obesity 4 | 678
Ophthalmoplegia 4 | 106
Optic Atrophy 4 | 242
Photodysphoria 4 | 121
Photophobia 4 | 121
Retinal pigment epithelial abnormality 4 | 111
Sensorineural Hearing Loss (disorder) 4 | 284
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
non primary Sjogren syndrome sicca 4 | 891
non-small cell lung cancer 4 | 2,890
Breast cancer 3 | 3,578
Difficulties with night vision 3 | 87
Gaucher disease type 1 3 | 180
Night Blindness 3 | 101
Pick disease 3 | 1,894
Waldenstrons macroglobulinemia 3 | 765
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
juvenile dermatomyositis 3 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
Amyotrophic lateral sclerosis 2 | 451
Low Vision 2 | 174
Lupus erythematosus 2 | 57
Mixed connective tissue disease 2 | 16
Neuronal ceroid lipofuscinosis 1 2 | 15
Pallor of optic disc 2 | 39
Retinitis pigmentosa 11 2 | 59
Rheumatoid arthritis 2 | 1,191
Visual Impairment 2 | 174
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
pancreatic cancer 2 | 2,398
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Class III malocclusion 1 | 78
Hypertrophy of lower jaw 1 | 78
Hypotrichosis simplex 1 | 7
Increased size of mandible 1 | 78
Mammary Neoplasms, Animal 1 | 136
Mandibular hyperplasia 1 | 78
Muscular atrophy 1 | 71
Weight Gain 1 | 100
X-linked dominant 1 | 57
interstitial lung disease 1 | 298
mandibular excess (physical finding) 1 | 78

Tissue

Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Female tissues 44 | 17,400
Liver and Pancreas 44 | 16,750
Male tissues 44 | 17,142
Nervous System 44 | 16,725
Respiratory system 44 | 16,393
Urinary Tract 44 | 16,678
Blood and immune system 43 | 16,909
Cardiovascular System 43 | 15,192
Skin and soft tissues 43 | 17,230

Target Family

Non-IDG 35 | 12,091
Enzyme 7 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Precatalytic spliceosome 45 | 45
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NACHT domain- and WD repeat-containing protein 1 NWD1 Tdark Non-IDG 0.08 1.22 3
Pre-mRNA-splicing factor CWC25 homolog CWC25 Tdark Non-IDG -0.71222 5.53 18
Telomerase protein component 1 TEP1 Tbio Enzyme -1.74492 50.6 71
Serine/threonine-protein kinase PRP4 homolog PRPF4B Tchem Kinase -1.17233 14.7 144
Splicing factor 3B subunit 2 SF3B2 Tbio Non-IDG -1.32229 20.7 163
Splicing factor 3B subunit 6 SF3B6 Tbio Non-IDG -0.65964 4.59 100
U6 snRNA-associated Sm-like protein LSm2 LSM2 Tbio Non-IDG -1.40226 23.0 121
Pre-mRNA-splicing factor 18 PRPF18 Tbio Non-IDG -1.36183 19.8 84
U6 snRNA-associated Sm-like protein LSm8 LSM8 Tdark Non-IDG -0.82004 6.23 34
Protein BUD31 homolog BUD31 Tbio Non-IDG -0.81132 6.98 172