Development Level

Tbio 40 | 11,445
Tclin 40 | 613
Tchem 13 | 1,598

Collection

Ion Channel: IDG Consortium (T... 17 | 99

IMPC Phenotype

abnormal behavior 6 | 298
hyperactivity 5 | 148
increased bone mineral content 3 | 108
preweaning lethality, complete... 3 | 979
abnormal behavioral response t... 2 | 66
decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
impaired glucose tolerance 2 | 75
increased mean corpuscular vol... 2 | 92
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased basophil cell number 1 | 16
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac stroke volum... 1 | 6
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased mean platelet volume 1 | 25
enlarged epididymis 1 | 31
increased body length 1 | 32
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
increased vertical activity 1 | 24
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened QT interval 1 | 4
shortened ST segment 1 | 10
tremors 1 | 39

Disease

Carcinoma 76 | 11,493
medulloblastoma, large-cell 47 | 6,241
ependymoma 46 | 4,679
glioblastoma 42 | 5,792
atypical teratoid / rhabdoid tumor 41 | 5,112
adult high grade glioma 40 | 3,801
group 3 medulloblastoma 35 | 4,104
psoriasis 35 | 6,694
oligodendroglioma 33 | 2,850
Astrocytoma, Pilocytic 31 | 3,081
lung cancer 31 | 4,740
primitive neuroectodermal tumor 31 | 3,035
Multiple Sclerosis 30 | 540
osteosarcoma 30 | 7,950
Epilepsy 29 | 792
Kidney cancer 29 | 2,613
astrocytic glioma 28 | 2,597
ovarian cancer 28 | 8,520
Eaton-Lambert syndrome 25 | 40
subependymal giant cell astrocytoma 25 | 2,287
lung carcinoma 24 | 2,843
pituitary cancer 22 | 1,972
Atrial Fibrillation 20 | 124
Breast cancer 20 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
Long QT syndrome 19 | 39
malignant mesothelioma 19 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
Intellectual disability 15 | 1,016
Pick disease 15 | 1,894
Seizures 15 | 596
cystic fibrosis 14 | 1,696
interstitial cystitis 14 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
pancreatic cancer 14 | 2,398
colon cancer 13 | 1,478
lung adenocarcinoma 13 | 2,716
Brugada syndrome 12 | 29
Heart disease 12 | 306
Schizophrenia 12 | 1,160
Autosomal recessive predisposition 11 | 1,442
Bipolar Disorder 10 | 666
Dull intelligence 10 | 645
Low intelligence 10 | 645
Mental Depression 10 | 333
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Muscle hypotonia 10 | 571
Poor school performance 10 | 645
invasive ductal carcinoma 10 | 2,951
non-small cell lung cancer 10 | 2,890
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
Paroxysmal atrial fibrillation 9 | 14
Prolonged QT interval 9 | 15
adrenocortical carcinoma 9 | 1,428
ductal carcinoma in situ 9 | 1,745
gastric carcinoma 9 | 807
Cardiac arrest 8 | 36
Depressive disorder 8 | 409
Hypertension 8 | 396
Hypokalemia 8 | 52
Liver cancer 8 | 604
Syncope 8 | 22
Ventricular Fibrillation 8 | 17
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 7 | 21
Cardiac Arrhythmia 7 | 103
Cerebellar Ataxia 7 | 304
Failure to gain weight 7 | 365
Familial atrial fibrillation 7 | 23
Long philtrum 7 | 137
Melanoma 7 | 711
Pediatric failure to thrive 7 | 365
Romano-Ward Syndrome 7 | 12
Skin cancer 7 | 469
Tonic - clonic seizures 7 | 44
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
sonic hedgehog group medulloblastoma 7 | 467
Amyotrophic lateral sclerosis 6 | 451
Anteverted nostril 6 | 191
Atrioventricular block 6 | 35
Brugada Syndrome (disorder) 6 | 15
Cardiomyopathy 6 | 116
Episodic ataxia 6 | 22
Long QT syndrome 1 6 | 20
Myoclonus 6 | 74
Osteoporosis 6 | 363
Small head 6 | 374
Sudden Cardiac Death 6 | 29
Timothy syndrome 6 | 11
Type 2 diabetes mellitus 6 | 272
active Crohn's disease 6 | 922
active ulcerative colitis 6 | 764
breast carcinoma 6 | 1,638
group 4 medulloblastoma 6 | 1,855
progressive supranuclear palsy 6 | 676
Vascular disease 5 | 319
chronic rhinosinusitis 5 | 512
primary pancreatic ductal adenocarcinoma 5 | 1,109

Tissue

Endocrine System 91 | 18,159
Nervous System 89 | 16,725
Digestive Tract 87 | 17,369
Female tissues 87 | 17,400
Male tissues 84 | 17,142
Skin and soft tissues 84 | 17,230
Liver and Pancreas 79 | 16,750
Urinary Tract 76 | 16,678
Blood and immune system 75 | 16,909
Respiratory system 73 | 16,393
Cardiovascular System 69 | 15,192

Target Family

Ion Channel 76 | 344
Non-IDG 7 | 12,091
Enzyme 6 | 4,145
Transporter 2 | 473
GPCR 1 | 408
Kinase 1 | 634

Compartment GO Term

Potassium channel complex 93 | 93
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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