Development Level

Tbio 90 | 11,445
Tclin 21 | 613
Tchem 15 | 1,598
Tdark 14 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

decreased total body fat amoun... 8 | 207
preweaning lethality, complete... 7 | 979
increased or absent threshold ... 5 | 101
preweaning lethality, incomple... 5 | 499
embryonic lethality prior to t... 4 | 278
abnormal behavior 3 | 298
abnormal retina morphology 3 | 71
decreased body weight 3 | 161
abnormal cornea morphology 2 | 31
decreased circulating HDL chol... 2 | 68
decreased circulating phosphat... 2 | 27
decreased exploration in new e... 2 | 11
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
edema 2 | 59
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating chloride... 2 | 41
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal hindbrain morphology 1 | 10
abnormal iris pigmentation 1 | 4
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
brachydactyly 1 | 19
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased cardiac muscle contr... 1 | 11
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
increased IgG2b level 1 | 1
increased body weight 1 | 25
increased cardiac muscle contr... 1 | 8
increased caudal vertebrae num... 1 | 7
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
small superior vagus ganglion 1 | 74
small testis 1 | 58
syndactyly 1 | 23
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 114 | 11,493
medulloblastoma, large-cell 101 | 6,241
atypical teratoid / rhabdoid tumor 98 | 5,112
glioblastoma 93 | 5,792
ependymoma 83 | 4,679
adult high grade glioma 79 | 3,801
oligodendroglioma 65 | 2,850
osteosarcoma 65 | 7,950
ovarian cancer 65 | 8,520
Astrocytoma, Pilocytic 64 | 3,081
Schizophrenia 62 | 1,160
group 3 medulloblastoma 60 | 4,104
primitive neuroectodermal tumor 60 | 3,035
astrocytic glioma 56 | 2,597
psoriasis 53 | 6,694
lung cancer 48 | 4,740
subependymal giant cell astrocytoma 47 | 2,287
Kidney cancer 43 | 2,613
Pick disease 40 | 1,894
Breast cancer 36 | 3,578
lung carcinoma 35 | 2,843
Bipolar Disorder 32 | 666
malignant mesothelioma 31 | 3,232
Intellectual disability 29 | 1,016
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
pituitary cancer 27 | 1,972
Epilepsy 26 | 792
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
Alzheimer's disease 25 | 658
group 4 medulloblastoma 24 | 1,855
Autistic Disorder 22 | 364
invasive ductal carcinoma 22 | 2,951
lung adenocarcinoma 22 | 2,716
Toxic encephalopathy 21 | 141
non-small cell lung cancer 20 | 2,890
Amyotrophic lateral sclerosis 19 | 451
Major Depressive Disorder 19 | 301
Parkinson's disease 19 | 392
tuberculosis 19 | 2,010
Depressive disorder 18 | 409
interstitial cystitis 18 | 2,312
pancreatic cancer 18 | 2,398
Alcoholic Intoxication, Chronic 17 | 289
Cancer 17 | 2,499
Unipolar Depression 17 | 250
colon cancer 17 | 1,478
Melanoma 16 | 711
Mental Depression 16 | 333
acute quadriplegic myopathy 15 | 1,158
astrocytoma 15 | 1,146
cystic fibrosis 14 | 1,696
ductal carcinoma in situ 14 | 1,745
spina bifida 14 | 1,074
Autosomal recessive predisposition 13 | 1,442
Cocaine-Related Disorders 13 | 92
Down syndrome 13 | 499
Dull intelligence 13 | 645
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Mood Disorders 13 | 184
Poor school performance 13 | 645
medulloblastoma 13 | 720
Cerebrovascular disease 12 | 238
Skin cancer 12 | 469
Cognitive delay 11 | 608
Global developmental delay 11 | 608
Liver cancer 11 | 604
Mental and motor retardation 11 | 608
Neurodegenerative disease 11 | 414
Seizures 11 | 596
juvenile dermatomyositis 11 | 1,187
General anesthesia 10 | 53
Local anesthesia 10 | 40
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Atopic dermatitis 9 | 952
Attention deficit hyperactivity disorder 9 | 278
Autism spectrum disorder 9 | 101
Dementia 9 | 175
Multiple myeloma 9 | 1,332
Muscle hypotonia 9 | 571
active ulcerative colitis 9 | 764
pediatric high grade glioma 9 | 1,064
primary pancreatic ductal adenocarcinoma 9 | 1,109
ulcerative colitis 9 | 1,819
Fragile X syndrome 8 | 34
Heart disease 8 | 306
Huntington's disease 8 | 76
Rheumatoid arthritis 8 | 1,191
Status Epilepticus 8 | 98
breast carcinoma 8 | 1,638
diabetes mellitus 8 | 1,728
Endometrial cancer 7 | 311
active Crohn's disease 7 | 922
aldosterone-producing adenoma 7 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
cutaneous lupus erythematosus 7 | 1,057
dermatomyositis 7 | 966
gastric carcinoma 7 | 807

Tissue

Endocrine System 137 | 18,159
Nervous System 137 | 16,725
Female tissues 133 | 17,400
Urinary Tract 133 | 16,678
Digestive Tract 132 | 17,369
Male tissues 132 | 17,142
Skin and soft tissues 132 | 17,230
Blood and immune system 130 | 16,909
Liver and Pancreas 129 | 16,750
Respiratory system 125 | 16,393
Cardiovascular System 117 | 15,192

Target Family

Non-IDG 83 | 12,091
Enzyme 24 | 4,145
Ion Channel 17 | 344
Kinase 9 | 634
GPCR 5 | 408
Epigenetic 1 | 242
Transporter 1 | 473

Compartment GO Term

Postsynaptic specialization 140 | 140
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Connector enhancer of kinase suppressor of ras 2 CNKSR2 Tbio Enzyme -1.11551 14.5 71
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.64427 3.70 175
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.91757 81.2 178
Brain and acute leukemia cytoplasmic protein BAALC Tbio Non-IDG -1.65293 47.9 117
Glutamate receptor-interacting protein 1 GRIP1 Tbio Non-IDG -2.18570 152.7 157
Synapsin-1 SYN1 Tbio Non-IDG -2.86836 712.4 770
Disks large-associated protein 3 DLGAP3 Tbio Non-IDG -1.26274 19.1 94
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 MAGI2 Tbio Enzyme -1.54170 33.0 178
Leucine-rich repeat-containing protein 7 LRRC7 Tbio Non-IDG -1.45630 31.2 41