Development Level

Tbio 109 | 11,651
Tclin 60 | 612
Tdark 22 | 6,593
Tchem 16 | 1,388

Collection

Ion Channel: IDG Consortium (T... 15 | 99
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

decreased total body fat amoun... 8 | 207
preweaning lethality, complete... 5 | 979
abnormal behavior 4 | 298
decreased body weight 4 | 161
increased or absent threshold ... 4 | 101
decreased vertical activity 3 | 208
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal joint morphology 2 | 23
abnormal retina morphology 2 | 71
brachydactyly 2 | 19
decreased circulating HDL chol... 2 | 68
decreased exploration in new e... 2 | 11
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hyperactivity 2 | 148
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating chloride... 2 | 41
increased heart weight 2 | 62
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
syndactyly 2 | 23
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal iris pigmentation 1 | 4
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased bone mineral content 1 | 151
decreased cardiac muscle contr... 1 | 11
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
hydroencephaly 1 | 14
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased caudal vertebrae num... 1 | 7
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 169 | 11,493
medulloblastoma, large-cell 131 | 6,241
atypical teratoid / rhabdoid tumor 119 | 5,112
glioblastoma 115 | 5,792
ependymoma 104 | 4,679
adult high grade glioma 96 | 3,801
psoriasis 83 | 6,694
Schizophrenia 78 | 1,160
ovarian cancer 78 | 8,520
Astrocytoma, Pilocytic 76 | 3,081
osteosarcoma 75 | 7,950
primitive neuroectodermal tumor 74 | 3,035
group 3 medulloblastoma 73 | 4,104
oligodendroglioma 73 | 2,850
astrocytic glioma 72 | 2,597
Kidney cancer 65 | 2,613
lung cancer 64 | 4,740
lung carcinoma 48 | 2,843
subependymal giant cell astrocytoma 48 | 2,287
Bipolar Disorder 46 | 666
Breast cancer 44 | 3,578
Epilepsy 44 | 792
Pick disease 43 | 1,894
General anesthesia 40 | 53
Autistic Disorder 38 | 364
pituitary cancer 38 | 1,972
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,291
Intellectual disability 34 | 1,016
Alcoholic Intoxication, Chronic 33 | 289
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
group 4 medulloblastoma 30 | 1,855
invasive ductal carcinoma 30 | 2,951
malignant mesothelioma 30 | 3,232
lung adenocarcinoma 29 | 2,716
Tonic-clonic epilepsy 25 | 47
Autosomal recessive predisposition 24 | 1,442
non-small cell lung cancer 24 | 2,890
Depressive disorder 23 | 409
Mental Depression 23 | 333
interstitial cystitis 23 | 2,312
Alcohol dependence 22 | 107
Muscle hypotonia 22 | 571
colon cancer 22 | 1,478
ductal carcinoma in situ 22 | 1,745
Liver cancer 21 | 604
Major Depressive Disorder 21 | 301
Seizures 21 | 596
Local anesthesia 20 | 40
Melanoma 20 | 711
Anxiety 19 | 136
Parkinson's disease 19 | 392
breast carcinoma 19 | 1,638
cystic fibrosis 19 | 1,696
pancreatic cancer 19 | 2,398
tuberculosis 19 | 2,010
Amyotrophic lateral sclerosis 18 | 451
Mood Disorders 18 | 184
Skin cancer 18 | 469
medulloblastoma 18 | 720
Dull intelligence 17 | 645
Low intelligence 17 | 645
Mental Retardation 17 | 645
Mental deficiency 17 | 645
Poor school performance 17 | 645
Insomnia 16 | 20
Nicotine dependence 16 | 54
Unipolar Depression 16 | 250
Alcoholism 15 | 45
Alzheimer's disease 15 | 658
Cognitive delay 15 | 608
Global developmental delay 15 | 608
Lennox-Gastaut syndrome 15 | 34
Mental and motor retardation 15 | 608
astrocytoma 15 | 1,146
pediatric high grade glioma 15 | 1,064
ulcerative colitis 15 | 1,819
Autism spectrum disorder 14 | 101
Cocaine-Related Disorders 14 | 92
Neuropathy 14 | 261
Simple partial seizure 14 | 26
acute quadriplegic myopathy 14 | 1,158
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Sedation as Adjunct to Anesthesia 13 | 15
juvenile dermatomyositis 13 | 1,187
spina bifida 13 | 1,074
Epilepsy characterized by intractable complex partial seizures 12 | 28
Infantile onset 12 | 238
Migraine Prevention 12 | 23
Peptic Ulcer 12 | 27
Toxic encephalopathy 12 | 141
progressive supranuclear palsy 12 | 676
Down syndrome 11 | 499
Endometrial cancer 11 | 311
Schizoaffective Disorder 11 | 55
Status Epilepticus 11 | 98
adrenocortical carcinoma 11 | 1,428
dermatomyositis 11 | 966
non primary Sjogren syndrome sicca 11 | 891
primary pancreatic ductal adenocarcinoma 11 | 1,109

Tissue

Endocrine System 203 | 18,159
Nervous System 200 | 16,725
Digestive Tract 194 | 17,369
Female tissues 193 | 17,400
Skin and soft tissues 192 | 17,230
Male tissues 188 | 17,142
Blood and immune system 183 | 16,909
Urinary Tract 182 | 16,678
Liver and Pancreas 179 | 16,750
Respiratory system 170 | 16,393
Cardiovascular System 149 | 15,192

Target Family

Non-IDG 103 | 12,091
Ion Channel 66 | 344
Enzyme 22 | 4,145
GPCR 11 | 408
Kinase 4 | 634
Epigenetic 1 | 242

Compartment GO Term

Postsynaptic membrane 207 | 207
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Protein TANC1 TANC1 Tdark Non-IDG -1.18264 15.5 31
Disks large homolog 2 DLG2 Tbio Non-IDG -1.75838 53.6 227
Leucine-rich repeat and fibronectin type-III domain-containing protein 2 LRFN2 Tbio Non-IDG -0.81315 6.12 97
Voltage-dependent calcium channel gamma-8 subunit CACNG8 Tdark Ion Channel -0.25756 2.01 67
Leucine-rich repeat and fibronectin type-III domain-containing protein 3 LRFN3 Tdark Non-IDG -0.48565 2.89 63
SHC-transforming protein 4 SHC4 Tbio Non-IDG -2.45096 295.5 129
Leucine-rich repeat-containing protein 4C LRRC4C Tbio Non-IDG -2.22551 163.3 161
Melanoma-associated antigen E1 MAGEE1 Tbio Non-IDG -1.88911 72.3 47
Leucine-rich repeat transmembrane neuronal protein 2 LRRTM2 Tbio Non-IDG -0.86860 8.30 115