Development Level

Tbio 162 | 11,178
Tclin 68 | 612
Tchem 43 | 1,885
Tdark 21 | 6,569

Collection

Ion Channel: IDG Consortium (T... 15 | 99
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 14 | 979
abnormal behavior 10 | 298
decreased total body fat amoun... 10 | 207
preweaning lethality, incomple... 10 | 499
embryonic lethality prior to t... 8 | 278
decreased body weight 6 | 161
abnormal retina morphology 5 | 71
decreased vertical activity 5 | 208
embryonic lethality prior to o... 5 | 239
increased bone mineral content 5 | 108
increased or absent threshold ... 5 | 101
abnormal bone structure 4 | 187
decreased mean corpuscular vol... 4 | 79
enlarged heart 4 | 210
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
abnormal embryo size 3 | 220
decreased circulating HDL chol... 3 | 68
decreased grip strength 3 | 116
increased circulating chloride... 3 | 41
increased heart weight 3 | 62
increased neutrophil cell numb... 3 | 46
increased startle reflex 3 | 112
prenatal lethality prior to he... 3 | 87
abnormal coat appearance 2 | 31
abnormal cornea morphology 2 | 31
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal joint morphology 2 | 23
abnormal lens morphology 2 | 81
abnormal retinal vasculature m... 2 | 27
abnormal sleep behavior 2 | 70
abnormal testis morphology 2 | 43
abnormal vertebrae morphology 2 | 18
brachydactyly 2 | 19
decreased bone mineral content 2 | 151
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased exploration in new e... 2 | 11
decreased lymphocyte cell numb... 2 | 83
decreased spleen weight 2 | 10
edema 2 | 59
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
hypoactivity 2 | 132
increased body weight 2 | 25
increased circulating alkaline... 2 | 122
increased circulating sodium l... 2 | 71
increased total body fat amoun... 2 | 134
persistence of hyaloid vascula... 2 | 33
small testis 2 | 58
syndactyly 2 | 23
thin ventricular wall 2 | 24
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
cataract 1 | 92
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
impaired glucose tolerance 1 | 75
increased cardiac muscle contr... 1 | 8
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
polycystic kidney 1 | 15
small superior vagus ganglion 1 | 74

Disease

Carcinoma 234 | 11,192
medulloblastoma, large-cell 190 | 6,086
atypical teratoid / rhabdoid tumor 173 | 4,971
glioblastoma 171 | 5,635
ependymoma 154 | 4,559
adult high grade glioma 137 | 3,701
ovarian cancer 127 | 8,297
psoriasis 123 | 6,514
osteosarcoma 119 | 7,766
Astrocytoma, Pilocytic 116 | 3,006
group 3 medulloblastoma 112 | 4,002
Schizophrenia 110 | 1,136
oligodendroglioma 110 | 2,768
primitive neuroectodermal tumor 110 | 2,957
astrocytic glioma 99 | 2,530
lung cancer 97 | 4,607
Kidney cancer 90 | 2,548
subependymal giant cell astrocytoma 74 | 2,230
lung carcinoma 73 | 2,755
Bipolar Disorder 67 | 646
Breast cancer 66 | 3,469
Pick disease 66 | 1,856
Epilepsy 61 | 775
malignant mesothelioma 55 | 3,135
intraductal papillary-mucinous carcinoma (IPMC) 52 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 52 | 3,204
pituitary cancer 52 | 1,915
intraductal papillary-mucinous adenoma (IPMA) 50 | 2,872
Autistic Disorder 49 | 358
group 4 medulloblastoma 47 | 1,806
invasive ductal carcinoma 46 | 2,867
Intellectual disability 45 | 998
non-small cell lung cancer 44 | 2,799
lung adenocarcinoma 42 | 2,627
pancreatic cancer 42 | 2,322
Alcoholic Intoxication, Chronic 40 | 283
Alzheimer's disease 40 | 640
General anesthesia 40 | 53
Cancer 38 | 2,388
interstitial cystitis 38 | 2,237
Depressive disorder 37 | 401
colon cancer 34 | 1,428
Mental Depression 33 | 325
Autosomal recessive predisposition 32 | 1,407
Melanoma 32 | 689
cystic fibrosis 31 | 1,629
ductal carcinoma in situ 31 | 1,686
breast carcinoma 30 | 1,589
tuberculosis 30 | 1,963
Liver cancer 29 | 589
Parkinson's disease 29 | 378
Skin cancer 29 | 451
Major Depressive Disorder 28 | 293
Toxic encephalopathy 28 | 139
astrocytoma 28 | 1,113
ulcerative colitis 28 | 1,765
Seizures 27 | 584
acute quadriplegic myopathy 27 | 1,133
Mood Disorders 26 | 181
Tonic-clonic epilepsy 26 | 47
Amyotrophic lateral sclerosis 25 | 437
Alcohol dependence 24 | 107
Muscle hypotonia 24 | 562
Unipolar Depression 24 | 244
diabetes mellitus 24 | 1,683
pediatric high grade glioma 24 | 1,035
Down syndrome 23 | 480
Dull intelligence 23 | 634
Low intelligence 23 | 634
Mental Retardation 23 | 634
Mental deficiency 23 | 634
Poor school performance 23 | 634
Anxiety 22 | 135
medulloblastoma 22 | 702
adrenocortical carcinoma 21 | 1,385
spina bifida 21 | 1,053
Local anesthesia 20 | 40
Status Epilepticus 20 | 96
juvenile dermatomyositis 20 | 1,147
primary pancreatic ductal adenocarcinoma 20 | 1,071
Cerebrovascular disease 19 | 223
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,911
Autism spectrum disorder 18 | 99
Cocaine-Related Disorders 18 | 90
Cognitive delay 18 | 596
Global developmental delay 18 | 596
Mental and motor retardation 18 | 596
Neurodegenerative disease 18 | 402
Rheumatoid arthritis 18 | 1,156
Attention deficit hyperactivity disorder 17 | 272
Atopic dermatitis 16 | 915
Insomnia 16 | 20
Nicotine dependence 16 | 54
Tetanus 16 | 67
active Crohn's disease 16 | 882
Multiple myeloma 15 | 1,296
cutaneous lupus erythematosus 15 | 1,016
dermatomyositis 15 | 941
gastric carcinoma 15 | 781
non primary Sjogren syndrome sicca 15 | 861

Tissue

Endocrine System 287 | 18,159
Nervous System 281 | 16,725
Digestive Tract 275 | 17,369
Female tissues 274 | 17,400
Skin and soft tissues 272 | 17,230
Male tissues 268 | 17,142
Urinary Tract 263 | 16,678
Blood and immune system 261 | 16,909
Liver and Pancreas 259 | 16,750
Respiratory system 248 | 16,393
Cardiovascular System 224 | 15,192

Target Family

Non-IDG 156 | 12,091
Ion Channel 69 | 344
Enzyme 36 | 4,145
GPCR 14 | 408
Kinase 13 | 634
Transporter 3 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

Compartment GO Term

Postsynapse 294 | 294
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Disks large-associated protein 2 DLGAP2 Tbio Non-IDG -1.34061 22.6 54
Glycine receptor subunit alpha-4 GLRA4 Tdark Ion Channel 0.12 0.95 18
Glutamate receptor ionotropic, kainate 5 GRIK5 Tclin Ion Channel -2.11616 127.3 179
DnaJ homolog subfamily A member 3, mitochondrial DNAJA3 Tbio Non-IDG -1.55298 43.3 192
BDNF/NT-3 growth factors receptor NTRK2 Tchem Kinase -3.14477 1170.3 947
Disks large homolog 5 DLG5 Tbio Non-IDG -1.71553 56.2 60
Nuclear receptor subfamily 1 group D member 1 NR1D1 Tchem Nuclear Receptor -1.95952 81.6 389
ADP-ribosylation factor 4 ARF4 Tbio Enzyme -1.67012 46.6 163