Development Level

Tbio 170 | 11,651
Tclin 68 | 612
Tchem 34 | 1,388
Tdark 24 | 6,593

Collection

Ion Channel: IDG Consortium (T... 15 | 99
RFA-RM-18-021 14 | 328
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 11 | 499
abnormal behavior 10 | 298
decreased total body fat amoun... 10 | 207
embryonic lethality prior to t... 8 | 278
decreased body weight 6 | 161
abnormal retina morphology 5 | 71
decreased vertical activity 5 | 208
embryonic lethality prior to o... 5 | 239
increased bone mineral content 5 | 108
increased or absent threshold ... 5 | 101
abnormal bone structure 4 | 187
decreased mean corpuscular vol... 4 | 79
enlarged heart 4 | 210
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
abnormal embryo size 3 | 220
decreased circulating HDL chol... 3 | 68
decreased grip strength 3 | 116
increased circulating chloride... 3 | 41
increased heart weight 3 | 62
increased neutrophil cell numb... 3 | 46
increased startle reflex 3 | 112
prenatal lethality prior to he... 3 | 87
abnormal coat appearance 2 | 31
abnormal cornea morphology 2 | 31
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal joint morphology 2 | 23
abnormal lens morphology 2 | 81
abnormal retinal vasculature m... 2 | 27
abnormal sleep behavior 2 | 70
abnormal testis morphology 2 | 43
abnormal vertebrae morphology 2 | 18
brachydactyly 2 | 19
decreased bone mineral content 2 | 151
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased exploration in new e... 2 | 11
decreased lymphocyte cell numb... 2 | 83
decreased spleen weight 2 | 10
edema 2 | 59
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
hypoactivity 2 | 132
increased body weight 2 | 25
increased circulating alkaline... 2 | 122
increased circulating sodium l... 2 | 71
increased total body fat amoun... 2 | 134
persistence of hyaloid vascula... 2 | 33
small testis 2 | 58
syndactyly 2 | 23
thin ventricular wall 2 | 24
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal neural tube closure 1 | 46
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
cataract 1 | 92
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased cardiac muscle contr... 1 | 8
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
premature death 1 | 5
small superior vagus ganglion 1 | 74

Disease

Carcinoma 236 | 11,493
medulloblastoma, large-cell 192 | 6,241
atypical teratoid / rhabdoid tumor 175 | 5,112
glioblastoma 172 | 5,792
ependymoma 156 | 4,679
adult high grade glioma 138 | 3,801
ovarian cancer 129 | 8,520
psoriasis 124 | 6,694
osteosarcoma 121 | 7,950
Astrocytoma, Pilocytic 116 | 3,081
group 3 medulloblastoma 113 | 4,104
oligodendroglioma 112 | 2,850
Schizophrenia 111 | 1,160
primitive neuroectodermal tumor 110 | 3,035
astrocytic glioma 101 | 2,597
lung cancer 98 | 4,740
Kidney cancer 90 | 2,613
subependymal giant cell astrocytoma 75 | 2,287
lung carcinoma 74 | 2,843
Bipolar Disorder 68 | 666
Breast cancer 68 | 3,578
Pick disease 68 | 1,894
Epilepsy 62 | 792
malignant mesothelioma 56 | 3,232
pituitary cancer 53 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 52 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 52 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 50 | 2,955
Autistic Disorder 49 | 364
group 4 medulloblastoma 47 | 1,855
Intellectual disability 46 | 1,016
invasive ductal carcinoma 46 | 2,951
non-small cell lung cancer 45 | 2,890
pancreatic cancer 43 | 2,398
lung adenocarcinoma 42 | 2,716
Alzheimer's disease 41 | 658
Alcoholic Intoxication, Chronic 40 | 289
General anesthesia 40 | 53
Cancer 39 | 2,499
Depressive disorder 38 | 409
interstitial cystitis 38 | 2,312
Mental Depression 34 | 333
colon cancer 34 | 1,478
Autosomal recessive predisposition 32 | 1,442
Melanoma 32 | 711
cystic fibrosis 31 | 1,696
ductal carcinoma in situ 31 | 1,745
Parkinson's disease 30 | 392
breast carcinoma 30 | 1,638
tuberculosis 30 | 2,010
Liver cancer 29 | 604
Skin cancer 29 | 469
Toxic encephalopathy 29 | 141
Major Depressive Disorder 28 | 301
Seizures 28 | 596
astrocytoma 28 | 1,146
ulcerative colitis 28 | 1,819
acute quadriplegic myopathy 27 | 1,158
Amyotrophic lateral sclerosis 26 | 451
Mood Disorders 26 | 184
Tonic-clonic epilepsy 26 | 47
Alcohol dependence 24 | 107
Down syndrome 24 | 499
Dull intelligence 24 | 645
Low intelligence 24 | 645
Mental Retardation 24 | 645
Mental deficiency 24 | 645
Muscle hypotonia 24 | 571
Poor school performance 24 | 645
Unipolar Depression 24 | 250
diabetes mellitus 24 | 1,728
pediatric high grade glioma 24 | 1,064
medulloblastoma 23 | 720
Anxiety 22 | 136
adrenocortical carcinoma 21 | 1,428
juvenile dermatomyositis 21 | 1,187
primary pancreatic ductal adenocarcinoma 21 | 1,109
spina bifida 21 | 1,074
Cerebrovascular disease 20 | 238
Local anesthesia 20 | 40
Status Epilepticus 20 | 98
Cognitive delay 19 | 608
Global developmental delay 19 | 608
Mental and motor retardation 19 | 608
Neurodegenerative disease 19 | 414
Rheumatoid arthritis 19 | 1,191
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
Autism spectrum disorder 18 | 101
Cocaine-Related Disorders 18 | 92
Attention deficit hyperactivity disorder 17 | 278
Atopic dermatitis 16 | 952
Dementia 16 | 175
Insomnia 16 | 20
Nicotine dependence 16 | 54
Tetanus 16 | 68
active Crohn's disease 16 | 922
dermatomyositis 16 | 966
Multiple myeloma 15 | 1,332
cutaneous lupus erythematosus 15 | 1,057
non primary Sjogren syndrome sicca 15 | 891

Tissue

Endocrine System 289 | 18,159
Nervous System 283 | 16,725
Digestive Tract 277 | 17,369
Female tissues 276 | 17,400
Skin and soft tissues 274 | 17,230
Male tissues 270 | 17,142
Urinary Tract 265 | 16,678
Blood and immune system 263 | 16,909
Liver and Pancreas 261 | 16,750
Respiratory system 250 | 16,393
Cardiovascular System 226 | 15,192

Target Family

Non-IDG 158 | 12,091
Ion Channel 69 | 344
Enzyme 36 | 4,145
GPCR 14 | 408
Kinase 13 | 634
Transporter 3 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

Compartment GO Term

Postsynapse 296 | 296
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Protein TANC1 TANC1 Tdark Non-IDG -1.18264 15.5 31
Disks large homolog 2 DLG2 Tbio Non-IDG -1.75838 53.6 227
Myotubularin-related protein 2 MTMR2 Tbio Enzyme -1.64906 46.5 124
Leucine-rich repeat and fibronectin type-III domain-containing protein 2 LRFN2 Tbio Non-IDG -0.81315 6.12 97
Voltage-dependent calcium channel gamma-2 subunit CACNG2 Tbio Ion Channel -1.92203 89.6 173
KICSTOR complex protein kaptin KPTN Tbio Non-IDG -1.45875 26.8 153
Synaptotagmin-11 SYT11 Tbio Non-IDG -1.00759 12.5 125
Leucine-rich repeat and fibronectin type-III domain-containing protein 3 LRFN3 Tdark Non-IDG -0.48565 2.89 63
SHC-transforming protein 4 SHC4 Tbio Non-IDG -2.45096 295.5 129