Development Level

Tbio 148 | 10,625
Tclin 65 | 602
Tchem 40 | 1,890
Tdark 20 | 7,003

Collection

Eligible Ion Channel Proteins 22 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 10 | 633
decreased total body fat amoun... 8 | 186
preweaning lethality, incomple... 8 | 260
decreased body weight 6 | 174
embryonic lethality prior to t... 6 | 187
decreased lean body mass 5 | 195
enlarged heart 5 | 111
abnormal behavior 4 | 226
abnormal bone structure 4 | 131
decreased circulating HDL chol... 4 | 77
decreased grip strength 4 | 123
increased or absent threshold ... 4 | 128
decreased circulating choleste... 3 | 85
increased bone mineral content 3 | 92
increased lean body mass 3 | 107
increased mean corpuscular vol... 3 | 91
abnormal embryo size 2 | 112
abnormal retinal pigmentation 2 | 61
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 53
decreased circulating aspartat... 2 | 27
decreased circulating insulin ... 2 | 75
decreased exploration in new e... 2 | 9
decreased fasted circulating g... 2 | 49
decreased heart weight 2 | 44
decreased mean corpuscular vol... 2 | 50
decreased vertical activity 2 | 22
increased blood urea nitrogen ... 2 | 44
increased circulating chloride... 2 | 43
increased circulating phosphat... 2 | 24
increased heart weight 2 | 37
increased rib number 2 | 41
increased startle reflex 2 | 38
tremors 2 | 34
abnormal QRS complex 1 | 25
abnormal bone mineralization 1 | 55
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal vertebrae morphology 1 | 14
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean platelet volume 1 | 12
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased body weight 1 | 42
increased caudal vertebrae num... 1 | 8
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 9
increased grip strength 1 | 83
increased heart rate 1 | 17
increased mean corpuscular hem... 1 | 93
increased red blood cell distr... 1 | 21
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
shortened RR interval 1 | 19
shortened ST segment 1 | 9
small superior vagus ganglion 1 | 20
small testis 1 | 37
straub tail 1 | 26
thin ventricular wall 1 | 5
thrombocytopenia 1 | 46

Disease

medulloblastoma, large-cell 183 | 6,234
glioblastoma 152 | 5,572
atypical teratoid / rhabdoid tumor 147 | 4,369
ovarian cancer 115 | 8,484
psoriasis 115 | 6,685
pilocytic astrocytoma 114 | 3,086
oligodendroglioma 107 | 2,849
osteosarcoma 107 | 7,933
primitive neuroectodermal tumor 107 | 3,031
ependymoma 94 | 2,514
pediatric high grade glioma 88 | 2,712
Carcinoma 76 | 2,147
astrocytic glioma 75 | 2,241
lung cancer 74 | 4,466
subependymal giant cell astrocytoma 70 | 2,287
Schizophrenia 68 | 501
lung carcinoma 68 | 2,844
medulloblastoma 68 | 1,524
Pick disease 64 | 1,893
adult high grade glioma 64 | 2,148
Epilepsy 55 | 346
malignant mesothelioma 55 | 3,162
Breast cancer 54 | 3,094
astrocytoma 51 | 1,493
pituitary cancer 49 | 1,972
group 4 medulloblastoma 48 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 47 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,289
Autistic Disorder 44 | 320
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,956
invasive ductal carcinoma 44 | 2,950
posterior fossa group A ependymoma 41 | 1,511
General anesthesia 40 | 53
lung adenocarcinoma 39 | 2,713
non-small cell lung cancer 39 | 2,798
Alzheimer's disease 37 | 644
Intellectual disability 36 | 573
interstitial cystitis 34 | 2,299
Cancer 32 | 2,346
pancreatic cancer 32 | 2,300
sonic hedgehog group medulloblastoma 32 | 1,482
colon cancer 31 | 1,475
Bipolar Disorder 30 | 266
ductal carcinoma in situ 30 | 1,745
breast carcinoma 29 | 1,614
group 3 medulloblastoma 28 | 2,254
cystic fibrosis 27 | 1,665
Parkinson's disease 26 | 364
Tonic-clonic epilepsy 26 | 47
atypical teratoid/rhabdoid tumor 26 | 1,095
ulcerative colitis 25 | 2,087
Alcohol dependence 24 | 107
acute quadriplegic myopathy 24 | 1,157
posterior fossa group B ependymoma 24 | 1,530
Amyotrophic Lateral Sclerosis 23 | 431
Toxic encephalopathy 23 | 131
Down syndrome 21 | 548
Local anesthesia 20 | 40
Status Epilepticus 20 | 85
adrenocortical carcinoma 19 | 1,427
juvenile dermatomyositis 19 | 1,189
diabetes mellitus 18 | 1,663
primary pancreatic ductal adenocarcinoma 18 | 1,271
spina bifida 18 | 1,064
tuberculosis 18 | 1,557
Cocaine-Related Disorders 17 | 88
Neurodegenerative disease 17 | 383
Anxiety 16 | 24
Atopic dermatitis 16 | 944
Insomnia 16 | 20
Major Depressive Disorder 16 | 106
Nicotine dependence 16 | 53
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
Lennox-Gastaut syndrome 15 | 34
gastric carcinoma 15 | 832
Cerebrovascular disease 14 | 231
Neuropathy 14 | 210
Obesity 14 | 616
Rheumatoid Arthritis 14 | 1,160
Seizures 14 | 95
Simple partial seizure 14 | 26
Tetanus 14 | 66
dermatomyositis 14 | 933
non primary Sjogren syndrome sicca 14 | 840
Duchenne muscular dystrophy 13 | 602
Sedation as Adjunct to Anesthesia 13 | 15
active Crohn's disease 13 | 918
aldosterone-producing adenoma 13 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
progressive supranuclear palsy 13 | 674
Epilepsy characterized by intractable complex partial seizures 12 | 28
Irritable bowel syndrome 12 | 59
Migraine Prevention 12 | 22
Peptic ulcer 12 | 22
Attention deficit hyperactivity disorder 11 | 156
Multiple myeloma 11 | 1,327
cutaneous lupus erythematosus 11 | 1,056
esophageal adenocarcinoma 10 | 737
nasopharyngeal carcinoma 10 | 1,056
pancreatic carcinoma 10 | 567

Tissue

Female tissues 272 | 18,647
Endocrine System 270 | 18,512
Nervous System 270 | 18,561
Cardiovascular System 269 | 17,958
Digestive Tract 269 | 18,473
Liver and Pancreas 269 | 18,136
Urinary Tract 269 | 18,444
Blood and immune system 268 | 17,995
Male tissues 265 | 17,969
Skin and soft tissues 265 | 18,115
Respiratory system 264 | 17,484

Target Family

Non-IDG 142 | 11,971
Ion Channel 69 | 341
Enzyme 32 | 4,146
GPCR 13 | 406
Kinase 11 | 634
Transporter 3 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

Compartment GO Term

Postsynapse 273 | 273
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Sodium/calcium exchanger 2 SLC8A2 Tbio Transporter -1.56223 31.9 51
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
Striatin STRN Tbio Non-IDG -1.63637 51.0 118
Acetylcholine receptor subunit delta CHRND Tclin Ion Channel -1.23749 17.4 128
Cytoplasmic polyadenylation element-binding protein 3 CPEB3 Tbio Non-IDG -1.28920 20.4 75
Ferritin heavy chain FTH1 Tbio Non-IDG -2.95630 924.5 435
PH and SEC7 domain-containing protein 3 PSD3 Tbio Non-IDG -1.18771 15.6 120
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.39539 267.3 178