Development Level

Tbio 53 | 10,625
Tchem 26 | 1,890
Tclin 4 | 602
Tdark 4 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

abnormal lens morphology 3 | 73
increased KLRG1-positive NK ce... 3 | 9
increased NK cell number 3 | 19
preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 3 | 260
abnormal retina morphology 2 | 100
decreased NK T cell number 2 | 28
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased gamma-delta T cell n... 2 | 18
decreased total body fat amoun... 2 | 186
increased B cell number 2 | 23
increased CD4-positive, alpha ... 2 | 15
increased CD8-positive, alpha-... 2 | 11
increased Ly6C high monocyte n... 2 | 12
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
increased monocyte cell number 2 | 27
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal gait 1 | 51
abnormal maxilla morphology 1 | 16
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 11
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
absent pinna reflex 1 | 21
absent vibrissae 1 | 14
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD5-positive Ly6C-po... 1 | 4
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased dendritic cell numbe... 1 | 3
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased immature NK cell num... 1 | 1
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mature B cell number 1 | 25
decreased rib number 1 | 59
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
increased CD4-positive, CD25-p... 1 | 18
increased Ly6C low monocyte nu... 1 | 8
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased eosinophil cell numb... 1 | 9
increased gamma-delta T cell n... 1 | 16
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased mature NK cell numbe... 1 | 1
increased or absent threshold ... 1 | 128
increased plasmacytoid dendrit... 1 | 1
increased transitional stage T... 1 | 1
male infertility 1 | 62
microcephaly 1 | 3
mydriasis 1 | 9
narrow eye opening 1 | 15
oligodactyly 1 | 14
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
syndactyly 1 | 4
thrombocytopenia 1 | 46

Disease

ovarian cancer 42 | 8,484
osteosarcoma 33 | 7,933
Cancer 28 | 2,346
lung cancer 28 | 4,466
glioblastoma 25 | 5,572
Multiple myeloma 24 | 1,327
psoriasis 24 | 6,685
medulloblastoma, large-cell 21 | 6,234
diabetes mellitus 19 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
Breast cancer 16 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
Waldenstrons macroglobulinemia 15 | 765
invasive ductal carcinoma 15 | 2,950
non-small cell lung cancer 15 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
pilocytic astrocytoma 14 | 3,086
lung carcinoma 13 | 2,844
malignant mesothelioma 13 | 3,162
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
primitive neuroectodermal tumor 13 | 3,031
lung adenocarcinoma 12 | 2,713
oligodendroglioma 12 | 2,849
atypical teratoid/rhabdoid tumor 11 | 1,095
ependymoma 11 | 2,514
sonic hedgehog group medulloblastoma 11 | 1,482
Obesity 10 | 616
Pick disease 10 | 1,893
pediatric high grade glioma 10 | 2,712
Neurodegenerative disease 9 | 383
astrocytic glioma 9 | 2,241
atypical teratoid / rhabdoid tumor 9 | 4,369
cystic fibrosis 9 | 1,665
ductal carcinoma in situ 9 | 1,745
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 1,557
Anemia 8 | 252
Liver carcinoma 8 | 217
acute quadriplegic myopathy 8 | 1,157
adult high grade glioma 8 | 2,148
astrocytoma 8 | 1,493
breast carcinoma 8 | 1,614
medulloblastoma 8 | 1,524
pancreatic cancer 8 | 2,300
pituitary cancer 8 | 1,972
Carcinoma 7 | 2,147
Kidney disease 7 | 396
Stomach Neoplasms 7 | 282
adrenocortical carcinoma 7 | 1,427
dermatomyositis 7 | 933
group 4 medulloblastoma 7 | 1,875
interstitial cystitis 7 | 2,299
ulcerative colitis 7 | 2,087
Atopic dermatitis 6 | 944
Heart disease 6 | 279
Malaria 6 | 140
Rheumatoid Arthritis 6 | 1,160
Toxic encephalopathy 6 | 131
group 3 medulloblastoma 6 | 2,254
posterior fossa group B ependymoma 6 | 1,530
Atherosclerosis 5 | 275
Duchenne muscular dystrophy 5 | 602
Hypertension 5 | 287
Prostatic Neoplasms 5 | 471
Vascular disease 5 | 281
colon cancer 5 | 1,475
cutaneous lupus erythematosus 5 | 1,056
gastric carcinoma 5 | 832
inflammatory breast cancer 5 | 404
juvenile dermatomyositis 5 | 1,189
posterior fossa group A ependymoma 5 | 1,511
primary pancreatic ductal adenocarcinoma 5 | 1,271
spina bifida 5 | 1,064
Amyotrophic Lateral Sclerosis 4 | 431
Arthritis 4 | 248
Cerebrovascular disease 4 | 231
Coronary artery disease 4 | 240
Diamond-Blackfan anemia 4 | 28
Epilepsy 4 | 346
Glycogen storage disease V 4 | 7
Myopathy 4 | 128
Osteoporosis 4 | 257
Renal Cell Carcinoma 4 | 199
Schizophrenia 4 | 501
active Crohn's disease 4 | 918
chronic rhinosinusitis 4 | 512
fibroadenoma 4 | 557
Alzheimer's disease 3 | 644
Contact Dermatitis 3 | 80
Hypersensitivity reaction type II disease 3 | 235
Hypertensive disease 3 | 193
Myocardial Ischemia 3 | 169
Polycystic Ovary Syndrome 3 | 332
Seizures 3 | 95
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
esophageal adenocarcinoma 3 | 737
hepatocellular carcinoma 3 | 532
mucosa-associated lymphoid tissue lymphoma 3 | 480
nasopharyngeal carcinoma 3 | 1,056
tuberculosis and treatment for 6 months 3 | 686

Tissue

Digestive Tract 83 | 18,473
Female tissues 83 | 18,647
Nervous System 83 | 18,561
Urinary Tract 83 | 18,444
Blood and immune system 82 | 17,995
Cardiovascular System 82 | 17,958
Endocrine System 82 | 18,512
Liver and Pancreas 82 | 18,136
Male tissues 82 | 17,969
Respiratory system 82 | 17,484
Skin and soft tissues 81 | 18,115

Target Family

Non-IDG 41 | 11,971
Enzyme 40 | 4,146
Kinase 2 | 634
TF/Epigenetic 2 | 38
GPCR 1 | 406
Transporter 1 | 473

Compartment GO Term

Plastid 87 | 87
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Malate dehydrogenase, cytoplasmic MDH1 Tbio Enzyme -2.61325 409.6 244
Mitochondrial ribonuclease P protein 3 KIAA0391 Tbio Enzyme 66.3 56
Cytochrome b MT-CYB Tbio Non-IDG -3.74473 5676.0 122
NADP-dependent malic enzyme ME1 Tchem Non-IDG -1.96870 90.3 172
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.16121 152.6 207
60S ribosomal protein L32 RPL32 Tbio Non-IDG -2.15191 130.7 62
Lactoperoxidase LPO Tbio Enzyme -2.69742 442.5 160
10 kDa heat shock protein, mitochondrial HSPE1 Tbio Non-IDG -3.00667 987.9 390
60S ribosomal protein L14 RPL14 Tbio Non-IDG -1.67525 43.3 139
Glutathione reductase, mitochondrial GSR Tclin Enzyme -2.97339 830.6 224