Development Level

Tbio 58 | 11,651
Tchem 22 | 1,388
Tclin 3 | 612
Tdark 2 | 6,593

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
absent pinna reflex 2 | 23
decreased bone mineral density 2 | 126
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased mean corpuscular hem... 2 | 96
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal coat- hair morphology 1 | 19
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased CD4-positive, CD25-p... 1 | 1
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased effector memory CD4-... 1 | 1
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
thrombocytopenia 1 | 56

Disease

Carcinoma 49 | 11,493
ovarian cancer 42 | 8,520
lung cancer 31 | 4,740
osteosarcoma 30 | 7,950
glioblastoma 27 | 5,792
psoriasis 26 | 6,694
Cancer 24 | 2,499
Multiple myeloma 24 | 1,332
Breast cancer 21 | 3,578
diabetes mellitus 21 | 1,728
medulloblastoma, large-cell 21 | 6,241
group 3 medulloblastoma 20 | 4,104
atypical teratoid / rhabdoid tumor 17 | 5,112
non-small cell lung cancer 17 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
Autosomal recessive predisposition 15 | 1,442
ependymoma 15 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
Waldenstrons macroglobulinemia 14 | 765
adult high grade glioma 14 | 3,801
invasive ductal carcinoma 14 | 2,951
primitive neuroectodermal tumor 14 | 3,035
Astrocytoma, Pilocytic 13 | 3,081
lung adenocarcinoma 13 | 2,716
malignant mesothelioma 13 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
lung carcinoma 12 | 2,843
oligodendroglioma 12 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Neurodegenerative disease 10 | 414
Pick disease 10 | 1,894
ductal carcinoma in situ 10 | 1,745
Anemia 9 | 365
Kidney cancer 9 | 2,613
Obesity 9 | 678
tuberculosis 9 | 2,010
Carcinoma, Hepatocellular 8 | 228
Epilepsy 8 | 792
Liver carcinoma 8 | 240
acute quadriplegic myopathy 8 | 1,158
astrocytic glioma 8 | 2,597
astrocytoma 8 | 1,146
pancreatic cancer 8 | 2,398
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Heart disease 7 | 306
Schizophrenia 7 | 1,160
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
interstitial cystitis 7 | 2,312
ulcerative colitis 7 | 1,819
Atopic dermatitis 6 | 952
Coronary artery disease 6 | 268
Hypertension 6 | 396
Intellectual disability 6 | 1,016
Kidney disease 6 | 430
Malaria 6 | 160
Muscle hypotonia 6 | 571
Rheumatoid arthritis 6 | 1,191
Seizures 6 | 596
Stomach Neoplasms 6 | 300
Toxic encephalopathy 6 | 141
dermatomyositis 6 | 966
group 4 medulloblastoma 6 | 1,855
Atherosclerosis 5 | 291
Duchenne muscular dystrophy 5 | 601
Osteoporosis 5 | 363
Vascular disease 5 | 319
adrenocortical carcinoma 5 | 1,428
colon cancer 5 | 1,478
juvenile dermatomyositis 5 | 1,187
nasopharyngeal carcinoma 5 | 1,058
pediatric high grade glioma 5 | 1,064
spina bifida 5 | 1,074
Amyotrophic lateral sclerosis 4 | 451
Arthritis 4 | 290
Cerebrovascular disease 4 | 238
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Hepatomegaly 4 | 285
Liver Cirrhosis, Experimental 4 | 769
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Myopathy 4 | 185
Polycystic ovary syndrome 4 | 360
Poor school performance 4 | 645
Prostatic Neoplasms 4 | 495
Strabismus 4 | 270
active Crohn's disease 4 | 922
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,057
fibroadenoma 4 | 559
gastric cancer 4 | 459
hepatocellular carcinoma 4 | 547
posterior fossa group B ependymoma 4 | 416
primary pancreatic ductal adenocarcinoma 4 | 1,109
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Blood and immune system 82 | 16,909
Digestive Tract 80 | 17,369
Endocrine System 80 | 18,159
Female tissues 80 | 17,400
Liver and Pancreas 80 | 16,750
Nervous System 80 | 16,725
Male tissues 79 | 17,142
Skin and soft tissues 79 | 17,230
Urinary Tract 78 | 16,678
Respiratory system 77 | 16,393
Cardiovascular System 74 | 15,192

Target Family

Enzyme 41 | 4,145
Non-IDG 38 | 12,091
Kinase 2 | 634
Epigenetic 1 | 242
GPCR 1 | 408
TF/Epigenetic 1 | 38
Transporter 1 | 473

Compartment GO Term

Plastid 85 | 85
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein-lysine 6-oxidase LOX Tbio Enzyme -3.36257 2227.1 513
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 SAMHD1 Tbio Enzyme -3.96722 8709.0 274
ATPase inhibitor, mitochondrial ATP5IF1 Tbio Enzyme -2.19240 149.7 166
Histone acetyltransferase KAT6B KAT6B Tbio Epigenetic -2.30232 201.0 58
Glyceraldehyde-3-phosphate dehydrogenase GAPDH Tchem Enzyme -3.68189 4548.4 1886
Geranylgeranyl pyrophosphate synthase GGPS1 Tchem Enzyme -2.30083 190.0 301
Sodium/potassium-transporting ATPase subunit beta-3 ATP1B3 Tclin Transporter -1.10090 13.3 226
Phakinin BFSP2 Tbio Non-IDG -2.51557 325.7 81
Bcl-2-like protein 10 BCL2L10 Tchem Non-IDG -2.76119 562.2 165
Glutamine synthetase GLUL Tchem Enzyme -2.97629 845.2 377