Development Level

Tbio 471 | 10,625
Tchem 127 | 1,890
Tclin 120 | 602
Tdark 59 | 7,003

Collection

Eligible Ion Channel Proteins 27 | 117
Eligible non-olfactory GPCR Proteins 8 | 143
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 29 | 633
abnormal behavior 17 | 226
decreased lean body mass 17 | 195
decreased total body fat amoun... 16 | 186
abnormal bone structure 15 | 131
decreased body weight 14 | 174
decreased bone mineral density 14 | 126
decreased grip strength 14 | 123
decreased bone mineral content 13 | 157
decreased circulating HDL chol... 10 | 77
decreased circulating choleste... 10 | 85
increased circulating alkaline... 10 | 119
increased mean corpuscular vol... 10 | 91
abnormal bone mineralization 9 | 55
hypoactivity 9 | 89
increased or absent threshold ... 9 | 128
preweaning lethality, incomple... 9 | 260
decreased circulating triglyce... 8 | 83
embryonic lethality prior to t... 8 | 187
enlarged heart 8 | 111
increased blood urea nitrogen ... 8 | 44
increased body weight 8 | 42
abnormal retina morphology 7 | 100
abnormal retinal pigmentation 7 | 61
increased mean corpuscular hem... 7 | 93
tremors 7 | 34
decreased fasted circulating g... 6 | 49
decreased prepulse inhibition 6 | 52
hyperactivity 6 | 108
impaired glucose tolerance 6 | 52
increased grip strength 6 | 83
increased heart weight 6 | 37
abnormal gait 5 | 51
cardiovascular system phenotyp... 5 | 35
decreased startle reflex 5 | 48
improved glucose tolerance 5 | 56
increased bone mineral density 5 | 52
increased circulating choleste... 5 | 53
increased lean body mass 5 | 107
short tibia 5 | 82
abnormal lens morphology 4 | 73
decreased body length 4 | 108
decreased heart weight 4 | 44
increased bone mineral content 4 | 92
increased circulating chloride... 4 | 43
increased circulating creatini... 4 | 29
increased circulating total pr... 4 | 20
increased fasted circulating g... 4 | 68
persistence of hyaloid vascula... 4 | 22
thrombocytopenia 4 | 46
abnormal QRS complex 3 | 25
abnormal cornea morphology 3 | 24
abnormal locomotor activation 3 | 26
abnormal pelvic girdle bone mo... 3 | 11
abnormal skin morphology 3 | 23
abnormal vibrissa morphology 3 | 17
corneal opacity 3 | 25
decreased circulating LDL chol... 3 | 37
decreased circulating alanine ... 3 | 53
decreased circulating chloride... 3 | 32
decreased circulating free fat... 3 | 39
decreased circulating insulin ... 3 | 75
decreased hemoglobin content 3 | 53
decreased leukocyte cell numbe... 3 | 54
decreased mean corpuscular vol... 3 | 50
decreased vertical activity 3 | 22
embryonic lethality prior to o... 3 | 148
enlarged liver 3 | 3
increased B cell number 3 | 23
increased circulating HDL chol... 3 | 63
increased circulating iron lev... 3 | 25
increased circulating potassiu... 3 | 31
increased circulating sodium l... 3 | 71
increased hemoglobin content 3 | 45
increased leukocyte cell numbe... 3 | 37
increased rib number 3 | 41
increased startle reflex 3 | 38
lethargy 3 | 5
male infertility 3 | 62
shortened ST segment 3 | 9
small thymus 3 | 11
abnormal coat appearance 2 | 25
abnormal ear morphology 2 | 5
abnormal epididymis morphology 2 | 31
abnormal heart left ventricle ... 2 | 20
abnormal spleen morphology 2 | 36
abnormal whole-body plethysmog... 2 | 4
decreased T cell number 2 | 31
decreased caudal vertebrae num... 2 | 49
decreased circulating serum al... 2 | 79
decreased neutrophil cell numb... 2 | 37
decreased rib number 2 | 59
enlarged spleen 2 | 26
increased circulating aspartat... 2 | 17
increased circulating calcium ... 2 | 32
increased circulating serum al... 2 | 25
increased hematocrit 2 | 36
increased total body fat amoun... 2 | 57
straub tail 2 | 26
vertebral fusion 2 | 23

Disease

osteosarcoma 347 | 7,933
ovarian cancer 345 | 8,484
medulloblastoma, large-cell 341 | 6,234
psoriasis 326 | 6,685
glioblastoma 303 | 5,572
atypical teratoid / rhabdoid tumor 246 | 4,369
lung cancer 220 | 4,466
pilocytic astrocytoma 214 | 3,086
lung carcinoma 194 | 2,844
oligodendroglioma 193 | 2,849
Carcinoma 185 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 181 | 3,289
pediatric high grade glioma 175 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 173 | 2,956
primitive neuroectodermal tumor 169 | 3,031
malignant mesothelioma 165 | 3,162
Breast cancer 164 | 3,094
lung adenocarcinoma 162 | 2,713
intraductal papillary-mucinous carcinoma (IPMC) 161 | 2,988
non-small cell lung cancer 159 | 2,798
invasive ductal carcinoma 151 | 2,950
pancreatic cancer 146 | 2,300
Cancer 145 | 2,346
subependymal giant cell astrocytoma 143 | 2,287
ependymoma 142 | 2,514
interstitial cystitis 141 | 2,299
astrocytic glioma 139 | 2,241
pituitary cancer 133 | 1,972
ulcerative colitis 120 | 2,087
adult high grade glioma 115 | 2,148
cystic fibrosis 112 | 1,665
Pick disease 111 | 1,893
medulloblastoma 107 | 1,524
ductal carcinoma in situ 106 | 1,745
colon cancer 101 | 1,475
group 4 medulloblastoma 98 | 1,875
posterior fossa group A ependymoma 95 | 1,511
breast carcinoma 90 | 1,614
Schizophrenia 87 | 501
group 3 medulloblastoma 87 | 2,254
posterior fossa group B ependymoma 86 | 1,530
tuberculosis 84 | 1,557
astrocytoma 82 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 80 | 1,795
diabetes mellitus 79 | 1,663
primary pancreatic ductal adenocarcinoma 77 | 1,271
sonic hedgehog group medulloblastoma 75 | 1,482
atypical teratoid/rhabdoid tumor 73 | 1,095
Epilepsy 72 | 346
adrenocortical carcinoma 65 | 1,427
Obesity 64 | 616
gastric carcinoma 63 | 832
Alzheimer's disease 62 | 644
acute quadriplegic myopathy 62 | 1,157
spina bifida 60 | 1,064
Autistic Disorder 59 | 320
Kidney disease 59 | 396
active Crohn's disease 58 | 918
cutaneous lupus erythematosus 58 | 1,056
nasopharyngeal carcinoma 55 | 1,056
Intellectual disability 54 | 573
juvenile dermatomyositis 54 | 1,189
esophageal adenocarcinoma 52 | 737
Down syndrome 49 | 548
Rheumatoid Arthritis 49 | 1,160
Parkinson's disease 46 | 364
dermatomyositis 44 | 933
fibroadenoma 43 | 557
General anesthesia 42 | 53
Hypertension 41 | 287
Prostatic Neoplasms 41 | 471
nephrosclerosis 41 | 329
progressive supranuclear palsy 40 | 674
Bipolar Disorder 39 | 266
active ulcerative colitis 39 | 477
Atopic dermatitis 37 | 944
primary Sjogren syndrome 37 | 789
Duchenne muscular dystrophy 36 | 602
Mammary Neoplasms 36 | 410
Amyotrophic Lateral Sclerosis 34 | 431
Multiple myeloma 34 | 1,327
aldosterone-producing adenoma 34 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 34 | 499
non primary Sjogren syndrome sicca 33 | 840
Alcohol dependence 32 | 107
Cerebrovascular disease 32 | 231
mucosa-associated lymphoid tissue lymphoma 32 | 480
Endometriosis 31 | 535
Heart disease 31 | 279
Multiple Sclerosis 30 | 498
chronic rhinosinusitis 30 | 512
Atherosclerosis 29 | 275
Neurodegenerative disease 29 | 383
acute myeloid leukemia 29 | 780
Osteoporosis 28 | 257
Retinitis pigmentosa 28 | 153
Coronary artery disease 27 | 240
Tonic-clonic epilepsy 27 | 47
Waldenstrons macroglobulinemia 27 | 765
sarcoidosis 27 | 358

Tissue

Nervous System 763 | 18,561
Female tissues 760 | 18,647
Digestive Tract 759 | 18,473
Endocrine System 758 | 18,512
Liver and Pancreas 757 | 18,136
Urinary Tract 757 | 18,444
Blood and immune system 752 | 17,995
Cardiovascular System 750 | 17,958
Skin and soft tissues 746 | 18,115
Male tissues 744 | 17,969
Respiratory system 735 | 17,484

Target Family

Non-IDG 390 | 11,971
Enzyme 108 | 4,146
Ion Channel 99 | 341
Transporter 93 | 473
Kinase 45 | 634
GPCR 40 | 406
Epigenetic 2 | 242

Compartment GO Term

Plasma membrane region 777 | 777
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Teratocarcinoma-derived growth factor 1 TDGF1 Tbio Non-IDG 156.3 371
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Solute carrier family 13 member 1 SLC13A1 Tbio Transporter -1.70334 62.7 18
N-acetylated-alpha-linked acidic dipeptidase-like protein NAALADL1 Tbio Enzyme -1.30374 25.3 78
Equilibrative nucleoside transporter 4 SLC29A4 Tbio Transporter -1.79381 73.1 189
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
Sodium/hydrogen exchanger 4 SLC9A4 Tdark Transporter -1.25841 17.4 6
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.94494 110.6 235