Development Level

Tbio 170 | 11,445
Tchem 85 | 1,598
Tclin 84 | 613
Tdark 9 | 6,588

Collection

Ion Channel: IDG Consortium (T... 9 | 99
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 23 | 979
preweaning lethality, incomple... 12 | 499
embryonic lethality prior to o... 9 | 239
abnormal embryo size 8 | 220
embryonic lethality prior to t... 8 | 278
small superior vagus ganglion 8 | 74
abnormal behavior 7 | 298
decreased body weight 6 | 161
enlarged heart 6 | 210
decreased lymphocyte cell numb... 5 | 83
decreased total body fat amoun... 5 | 207
increased lean body mass 5 | 172
increased neutrophil cell numb... 5 | 46
increased startle reflex 5 | 112
thrombocytopenia 5 | 56
abnormal bone structure 4 | 187
decreased leukocyte cell numbe... 4 | 73
decreased vertical activity 4 | 208
hydrometra 4 | 53
increased bone mineral content 4 | 108
increased mean corpuscular hem... 4 | 96
increased mean corpuscular vol... 4 | 92
increased monocyte cell number 4 | 63
abnormal bone mineralization 3 | 38
abnormal epididymis morphology 3 | 42
abnormal heart morphology 3 | 162
abnormal seminal vesicle morph... 3 | 114
decreased bone mineral content 3 | 151
decreased erythrocyte cell num... 3 | 62
decreased heart weight 3 | 27
embryonic growth retardation 3 | 106
enlarged uterus 3 | 11
increased circulating sodium l... 3 | 71
increased circulating triglyce... 3 | 42
increased leukocyte cell numbe... 3 | 47
increased spleen weight 3 | 10
increased total body fat amoun... 3 | 134
abnormal eye anterior chamber ... 2 | 9
abnormal lung morphology 2 | 26
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
abnormal testis morphology 2 | 43
abnormal vertebrae morphology 2 | 18
decreased blood urea nitrogen ... 2 | 51
decreased circulating LDL chol... 2 | 38
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased circulating sodium l... 2 | 22
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased large unstained cell... 2 | 11
edema 2 | 59
enlarged lymph nodes 2 | 37
hemorrhage 2 | 23
hyperactivity 2 | 148
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased erythrocyte cell num... 2 | 39
increased hematocrit 2 | 46
increased lymphocyte cell numb... 2 | 32
limb grasping 2 | 41
short tibia 2 | 97
small testis 2 | 58
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal startle reflex 1 | 15
abnormal vibrissa morphology 1 | 25
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased eosinophil cell numb... 1 | 24
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased exploration in new e... 1 | 8
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
microphthalmia 1 | 26

Disease

Carcinoma 255 | 11,493
Cancer 230 | 2,499
osteosarcoma 203 | 7,950
psoriasis 185 | 6,694
glioblastoma 176 | 5,792
ovarian cancer 173 | 8,520
lung cancer 149 | 4,740
lung carcinoma 137 | 2,843
medulloblastoma, large-cell 125 | 6,241
atypical teratoid / rhabdoid tumor 122 | 5,112
adult high grade glioma 116 | 3,801
ependymoma 115 | 4,679
Astrocytoma, Pilocytic 114 | 3,081
interstitial cystitis 113 | 2,312
malignant mesothelioma 103 | 3,232
ulcerative colitis 97 | 1,819
Breast cancer 96 | 3,578
invasive ductal carcinoma 95 | 2,951
tuberculosis 95 | 2,010
non-small cell lung cancer 92 | 2,890
diabetes mellitus 89 | 1,728
Schizophrenia 88 | 1,160
subependymal giant cell astrocytoma 82 | 2,287
Kidney cancer 80 | 2,613
lung adenocarcinoma 80 | 2,716
Rheumatoid arthritis 78 | 1,191
intraductal papillary-mucinous carcinoma (IPMC) 77 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 77 | 3,291
Kidney disease 73 | 430
pancreatic cancer 73 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 71 | 2,955
cutaneous lupus erythematosus 69 | 1,057
Autosomal recessive predisposition 67 | 1,442
Hypersensitivity reaction type II disease 66 | 253
group 3 medulloblastoma 66 | 4,104
Arthritis 65 | 290
Anemia 63 | 365
cystic fibrosis 62 | 1,696
oligodendroglioma 60 | 2,850
primitive neuroectodermal tumor 60 | 3,035
Multiple Sclerosis 59 | 540
Liver Cirrhosis, Experimental 58 | 769
astrocytic glioma 54 | 2,597
Asthma 53 | 385
Hypertension 53 | 396
Heart disease 51 | 306
ductal carcinoma in situ 50 | 1,745
Inflammatory bowel disease 49 | 151
Thrombocytopenia 49 | 197
group 4 medulloblastoma 49 | 1,855
Lung disease 47 | 142
Obesity 47 | 678
pituitary cancer 47 | 1,972
Breast Neoplasms 45 | 445
Mammary Neoplasms 45 | 425
breast carcinoma 45 | 1,638
primary Sjogren syndrome 45 | 735
Alzheimer's disease 44 | 658
Coronary artery disease 44 | 268
Vascular disease 44 | 319
Atherosclerosis 43 | 291
Liver disease 43 | 237
Prostatic Neoplasms 43 | 495
Bipolar Disorder 42 | 666
pancreatic ductal adenocarcinoma liver metastasis 42 | 1,962
colon cancer 41 | 1,478
Diarrhea 39 | 253
astrocytoma 39 | 1,146
primary pancreatic ductal adenocarcinoma 39 | 1,109
periodontitis 38 | 293
Hypertensive disease 37 | 292
Stomach Neoplasms 37 | 300
Allergic hypersensitivity disease 36 | 126
adrenocortical carcinoma 36 | 1,428
Cerebrovascular disease 35 | 238
Depressive disorder 35 | 409
Dermatitis 35 | 157
Pick disease 35 | 1,894
Lung Neoplasms 34 | 232
Melanoma 34 | 711
Epilepsy 33 | 792
Neoplasm Invasiveness 33 | 161
Pneumonia 33 | 174
sarcoidosis 33 | 370
gastric carcinoma 32 | 807
Human immunodeficiency virus infectious disease 31 | 138
Inflammation 31 | 120
Malaria 31 | 160
Neoplasm Metastasis 31 | 168
pediatric high grade glioma 31 | 1,064
Arthritis, Rheumatoid 30 | 174
Influenza 30 | 142
Major Depressive Disorder 30 | 301
Multiple myeloma 30 | 1,332
dermatomyositis 30 | 966
juvenile dermatomyositis 30 | 1,187
Endometriosis 29 | 540
Mental Depression 29 | 333
Waldenstrons macroglobulinemia 29 | 765
nasopharyngeal carcinoma 29 | 1,058

Tissue

Endocrine System 340 | 18,159
Digestive Tract 332 | 17,369
Blood and immune system 331 | 16,909
Male tissues 331 | 17,142
Nervous System 329 | 16,725
Female tissues 328 | 17,400
Skin and soft tissues 326 | 17,230
Urinary Tract 325 | 16,678
Liver and Pancreas 324 | 16,750
Respiratory system 320 | 16,393
Cardiovascular System 297 | 15,192

Target Family

Non-IDG 207 | 12,091
Kinase 43 | 634
Ion Channel 41 | 344
Enzyme 23 | 4,145
Transcription Factor 20 | 1,400
GPCR 12 | 408
Epigenetic 1 | 242
Transporter 1 | 473

Compartment GO Term

Plasma membrane receptor compl... 348 | 348
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 13C TNFRSF13C Tbio Non-IDG -2.48953 288.2 437
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.61667 619.4 0
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Neuronal acetylcholine receptor subunit beta-2 CHRNB2 Tclin Ion Channel -1.62448 37.6 174
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168