Development Level

Tbio 21 | 11,445
Tclin 4 | 613
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal male genitalia morpho... 1 | 3
absent startle reflex 1 | 24
decreased bone mineral content 1 | 151
decreased brain size 1 | 4
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
fusion of vertebral arches 1 | 7
improved glucose tolerance 1 | 79
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased total body fat amoun... 1 | 134
polysyndactyly 1 | 2
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16
vertebral transformation 1 | 12

Disease

Infertility 22 | 188
Polycystic ovary syndrome 21 | 360
Hypogonadism 20 | 173
Amenorrhea 19 | 58
Autosomal recessive predisposition 15 | 1,442
Anovulation 14 | 21
Cancer 14 | 2,499
Osteoporosis 13 | 363
Hyperandrogenism 12 | 34
psoriasis 12 | 6,694
Carcinoma 11 | 11,493
Male infertility 11 | 206
Obesity 11 | 678
Endometriosis 10 | 540
Gynecomastia 10 | 64
Hypothyroidism 10 | 122
Premature ovarian failure 10 | 65
Cryptorchidism 9 | 296
Delayed Puberty 9 | 97
Delayed bone age 9 | 136
Generalized osteopenia 9 | 99
Hypopituitarism 9 | 40
Osteopenia 9 | 99
Primary physiologic amenorrhea 9 | 55
diabetes mellitus 9 | 1,728
ovarian cancer 9 | 8,520
Hypertension 8 | 396
Hyperthyroidism 8 | 53
Klinefelter's syndrome 8 | 56
Small testicle 8 | 75
pituitary cancer 8 | 1,972
Adenoma 7 | 167
Congenital hypoplasia of penis 7 | 176
Hyperinsulinism 7 | 133
Hyperprolactinemia 7 | 27
Hypoglycemia 7 | 152
Hypogonadotropic hypogonadism 7 | 89
Ovarian dysfunction 7 | 18
Ovarian hyperstimulation syndrome 7 | 19
Sparse pubic hair 7 | 31
Congenital adrenal hyperplasia 6 | 73
Cushing's syndrome 6 | 48
Decreased testosterone in males 6 | 28
Depressive disorder 6 | 409
Hypertensive disease 6 | 292
Hypogonadism, Isolated Hypogonadotropic 6 | 71
Kidney disease 6 | 430
Pituitary adenoma 6 | 38
Prostatic Neoplasms 6 | 495
osteosarcoma 6 | 7,950
Acromegaly 5 | 51
Alcoholic Intoxication, Chronic 5 | 289
Alzheimer's disease 5 | 658
Arthritis 5 | 290
Autistic Disorder 5 | 364
Breast cancer 5 | 3,578
Craniopharyngioma 5 | 16
Erectile dysfunction 5 | 32
Female hypogonadism syndrome 5 | 25
Female infertility 5 | 30
Heart disease 5 | 306
Infertility, Female 5 | 28
Infertility, Male 5 | 46
Leydig cell tumor 5 | 9
Liver Cirrhosis, Experimental 5 | 769
Liver disease 5 | 237
Low serum estradiol levels 5 | 22
McCune Albright syndrome 5 | 19
Precocious Puberty 5 | 28
Primary hypogonadism 5 | 37
Pseudohermaphroditism 5 | 16
Secondary physiologic amenorrhea 5 | 32
Sparse axillary hair 5 | 28
medulloblastoma, large-cell 5 | 6,241
Abnormality of metabolism/homeostasis 4 | 134
Abnormality of the voice 4 | 46
Alzheimer Disease 4 | 83
Anorexia nervosa 4 | 80
Atherosclerosis 4 | 291
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Cerebrovascular disease 4 | 238
Congenital hypoplasia of breast 4 | 25
Coronary artery disease 4 | 268
Decreased fertility 4 | 33
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Epilepsy 4 | 792
Fatty Liver 4 | 70
Hypospadias 4 | 53
Insulin Resistance 4 | 72
Lipid metabolism disorder 4 | 114
Mammary Neoplasms 4 | 425
Myopathy 4 | 185
Premature Menopause 4 | 31
Schizophrenia 4 | 1,160
Seizures 4 | 596
Tachycardia 4 | 43
Weight decreased 4 | 103
cystic fibrosis 4 | 1,696

Tissue

Endocrine System 26 | 18,159
Female tissues 24 | 17,400
Skin and soft tissues 24 | 17,230
Digestive Tract 23 | 17,369
Liver and Pancreas 23 | 16,750
Nervous System 22 | 16,725
Blood and immune system 21 | 16,909
Respiratory system 21 | 16,393
Urinary Tract 21 | 16,678
Male tissues 19 | 17,142
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 3 | 4,145
GPCR 3 | 408
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

Compartment GO Term

Pituitary gonadotropin complex 27 | 27
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.43406 2729.3 264
26S proteasome complex subunit SEM1 SEM1 Tbio Non-IDG -2.83524 645.6 109
Bile salt sulfotransferase SULT2A1 Tbio Enzyme -3.24754 1727.7 308
Lutropin-choriogonadotropic hormone receptor LHCGR Tclin GPCR -2.58909 376.4 243
Follistatin FST Tbio Non-IDG -3.07812 1179.4 356
Steroidogenic factor 1 NR5A1 Tchem Nuclear Receptor -2.91071 877.0 279
Progonadoliberin-2 GNRH2 Tbio Non-IDG -2.48485 284.6 122
Insulin-like 3 INSL3 Tbio Non-IDG -2.39911 280.0 135
Pro-opiomelanocortin POMC Tbio Non-IDG -4.56004 36591.2 1334