Development Level

Tbio 62 | 11,445
Tchem 7 | 1,598
Tdark 4 | 6,588
Tclin 3 | 613

IMPC Phenotype

abnormal behavior 3 | 298
decreased body weight 3 | 161
decreased circulating amylase ... 3 | 28
decreased circulating triglyce... 3 | 79
enlarged heart 3 | 210
increased lean body mass 3 | 172
limb grasping 3 | 41
abnormal heart morphology 2 | 162
absent pinna reflex 2 | 23
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
hyperactivity 2 | 148
hypoactivity 2 | 132
impaired righting response 2 | 26
increased circulating sodium l... 2 | 71
increased or absent threshold ... 2 | 101
stereotypic behavior 2 | 3
trunk curl 2 | 16
vertebral fusion 2 | 23
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal ear morphology 1 | 9
abnormal eye morphology 1 | 68
abnormal locomotor activation 1 | 16
abnormal pupil morphology 1 | 2
abnormal retina morphology 1 | 71
abnormal whole-body plethysmog... 1 | 4
absent startle reflex 1 | 24
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased cellular hemoglobin ... 1 | 1
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
macrophthalmia 1 | 2
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
premature death 1 | 5
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
short tibia 1 | 97
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 55 | 11,493
Retinitis Pigmentosa 41 | 226
Intellectual disability 34 | 1,016
Night Blindness 34 | 101
Difficulties with night vision 32 | 87
Autosomal recessive predisposition 31 | 1,442
Dull intelligence 31 | 645
Low intelligence 31 | 645
Mental Retardation 31 | 645
Mental deficiency 31 | 645
Poor school performance 31 | 645
Cataract 30 | 297
Electroretinogram abnormal 30 | 95
Lens Opacities 30 | 231
Nystagmus 30 | 317
Abnormality of retinal pigmentation 29 | 111
Photodysphoria 29 | 121
Photophobia 29 | 121
Retinal pigment epithelial abnormality 29 | 111
Sensorineural Hearing Loss (disorder) 29 | 284
Glaucoma 28 | 239
Blind Vision 27 | 111
osteosarcoma 27 | 7,950
Blindness, Legal 26 | 110
Broad flat nasal bridge 26 | 236
Nasal bridge wide 26 | 236
Optic Atrophy 26 | 242
psoriasis 26 | 6,694
Anteverted nostril 25 | 191
Keratoconus 25 | 113
Abnormality of the retinal vasculature 24 | 59
Atypical scarring of skin 24 | 62
Conductive hearing loss 24 | 123
Congenital anomaly of testis 24 | 52
Congenital hypoplasia of penis 24 | 176
Hyperinsulinism 24 | 133
Hypogonadism 24 | 173
Night blindness, progressive 24 | 51
Obesity 24 | 678
Ophthalmoplegia 24 | 106
Retinal Degeneration 24 | 106
Blindness 23 | 88
Fundus dystrophy 23 | 83
Cone dystrophy 22 | 71
medulloblastoma, large-cell 22 | 6,241
Low Vision 20 | 174
Visual Impairment 20 | 174
ependymoma 19 | 4,679
group 3 medulloblastoma 19 | 4,104
Leber congenital amaurosis 18 | 69
ovarian cancer 18 | 8,520
Reduced visual acuity 17 | 63
lung cancer 17 | 4,740
glioblastoma 15 | 5,792
lung carcinoma 15 | 2,843
Breast cancer 14 | 3,578
cone-rod dystrophy 14 | 59
lung adenocarcinoma 14 | 2,716
Abnormal color vision 13 | 31
Color vision defect 13 | 33
Color vision defect, severe 13 | 31
Kidney cancer 13 | 2,613
pituitary cancer 13 | 1,972
adult high grade glioma 12 | 3,801
atypical teratoid / rhabdoid tumor 12 | 5,112
Cancer 11 | 2,499
Visual field constriction 10 | 36
malignant mesothelioma 10 | 3,232
pancreatic cancer 10 | 2,398
astrocytic glioma 9 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
subependymal giant cell astrocytoma 9 | 2,287
Abnormality of macular pigmentation 8 | 16
Astrocytoma, Pilocytic 8 | 3,081
Epilepsy 8 | 792
Macular pigmentary changes 8 | 16
Melanoma 8 | 711
Seizures 8 | 596
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
non-small cell lung cancer 8 | 2,890
primitive neuroectodermal tumor 8 | 3,035
Abnormal vision 7 | 52
Enhanced S-cone syndrome 7 | 17
Pallor of optic disc 7 | 39
Usher syndrome 7 | 32
facioscapulohumeral dystrophy 7 | 288
group 4 medulloblastoma 7 | 1,855
invasive ductal carcinoma 7 | 2,951
oligodendroglioma 7 | 2,850
tuberculosis 7 | 2,010
ulcerative colitis 7 | 1,819
Cerebellar Ataxia 6 | 304
Cone/cone-rod dystrophy 6 | 20
Muscle hypotonia 6 | 571
Myopia 6 | 176
Pigmentary iris degeneration 6 | 20
Retinal Detachment 6 | 51
Schizophrenia 6 | 1,160
Skin cancer 6 | 469

Tissue

Endocrine System 71 | 18,159
Digestive Tract 66 | 17,369
Skin and soft tissues 64 | 17,230
Nervous System 61 | 16,725
Blood and immune system 58 | 16,909
Female tissues 57 | 17,400
Male tissues 56 | 17,142
Urinary Tract 54 | 16,678
Liver and Pancreas 52 | 16,750
Respiratory system 50 | 16,393
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 18 | 4,145
GPCR 8 | 408
Kinase 7 | 634
Ion Channel 3 | 344
Transcription Factor 3 | 1,400
Transporter 2 | 473

Compartment GO Term

Photoreceptor outer segment 76 | 76
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Neural retina-specific leucine zipper protein NRL Tbio Transcription Factor -2.46080 279.4 74
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Cone-rod homeobox protein CRX Tbio Transcription Factor -2.44826 272.0 185
Cell growth-regulating nucleolar protein LYAR Tbio Non-IDG -1.22816 19.3 156
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Retinal guanylyl cyclase 1 GUCY2D Tbio Kinase -2.20658 167.7 205
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Guanylyl cyclase-activating protein 3 GUCA1C Tdark Enzyme 0.02 1.10 125
Rhodopsin kinase GRK7 Tchem Kinase -1.83396 45.0 180