Development Level

Tchem 59 | 1,598
Tbio 38 | 11,445
Tclin 25 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 13 | 979
embryonic lethality prior to t... 5 | 278
decreased body weight 4 | 161
embryonic lethality prior to o... 4 | 239
preweaning lethality, incomple... 4 | 499
abnormal retina morphology 3 | 71
decreased circulating creatini... 3 | 39
increased mean corpuscular hem... 3 | 96
increased neutrophil cell numb... 3 | 46
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal bone mineralization 2 | 38
abnormal embryo size 2 | 220
abnormal gait 2 | 69
decreased circulating LDL chol... 2 | 38
decreased circulating aspartat... 2 | 34
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
enlarged uterus 2 | 11
increased circulating LDL chol... 2 | 13
increased circulating alkaline... 2 | 122
increased spleen weight 2 | 10
increased startle reflex 2 | 112
male infertility 2 | 123
short tibia 2 | 97
small superior vagus ganglion 2 | 74
thrombocytopenia 2 | 56
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 4
abnormal head morphology 1 | 10
abnormal maxilla morphology 1 | 17
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
absent testes 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased eosinophil cell numb... 1 | 11
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
mammalian phenotype 1 | 17
microphthalmia 1 | 26
thrombocytosis 1 | 27

Disease

Cancer 114 | 2,499
Carcinoma 96 | 11,493
ovarian cancer 86 | 8,520
osteosarcoma 74 | 7,950
lung cancer 69 | 4,740
psoriasis 65 | 6,694
glioblastoma 64 | 5,792
diabetes mellitus 59 | 1,728
medulloblastoma, large-cell 55 | 6,241
Breast cancer 54 | 3,578
atypical teratoid / rhabdoid tumor 50 | 5,112
Schizophrenia 45 | 1,160
Breast Neoplasms 44 | 445
Mammary Neoplasms 44 | 425
ependymoma 44 | 4,679
Kidney cancer 41 | 2,613
invasive ductal carcinoma 41 | 2,951
malignant mesothelioma 41 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
Obesity 38 | 678
Prostatic Neoplasms 38 | 495
Carcinoma, Hepatocellular 37 | 228
Liver carcinoma 37 | 240
Stomach Neoplasms 36 | 300
adult high grade glioma 36 | 3,801
ulcerative colitis 36 | 1,819
Alzheimer's disease 35 | 658
Kidney disease 35 | 430
Vascular disease 35 | 319
subependymal giant cell astrocytoma 35 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
non-small cell lung cancer 34 | 2,890
Astrocytoma, Pilocytic 33 | 3,081
Heart disease 33 | 306
interstitial cystitis 33 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
lung carcinoma 32 | 2,843
pancreatic cancer 32 | 2,398
breast carcinoma 31 | 1,638
lung adenocarcinoma 31 | 2,716
oligodendroglioma 30 | 2,850
Arthritis 29 | 290
Hypertension 29 | 396
Lung Neoplasms 29 | 232
Hyperglycemia 28 | 137
Neoplasm Metastasis 28 | 168
group 3 medulloblastoma 28 | 4,104
tuberculosis 28 | 2,010
Toxic encephalopathy 27 | 141
ductal carcinoma in situ 27 | 1,745
Autosomal recessive predisposition 26 | 1,442
Bipolar Disorder 26 | 666
Carcinoma, Squamous Cell 26 | 110
Neoplasm Invasiveness 26 | 161
Rheumatoid arthritis 26 | 1,191
Squamous cell carcinoma 26 | 129
astrocytic glioma 26 | 2,597
cystic fibrosis 26 | 1,696
group 4 medulloblastoma 26 | 1,855
Adenocarcinoma 25 | 122
primitive neuroectodermal tumor 25 | 3,035
Asthma 24 | 385
Cerebrovascular disease 24 | 238
acute quadriplegic myopathy 24 | 1,158
astrocytoma 24 | 1,146
Liver Cirrhosis, Experimental 23 | 769
Liver disease 23 | 237
Melanoma 23 | 711
Parkinson's disease 23 | 392
Anemia 22 | 365
Depressive disorder 22 | 409
Hypertensive disease 22 | 292
Lung disease 22 | 142
Pick disease 22 | 1,894
Adenoma 21 | 167
Atherosclerosis 21 | 291
Inflammation 21 | 120
Intellectual disability 21 | 1,016
Multiple Sclerosis 21 | 540
Ovarian Neoplasms 21 | 102
Seizures 21 | 596
adrenocortical carcinoma 21 | 1,428
Brain Ischemia 20 | 110
Cell Transformation, Neoplastic 20 | 97
Colonic Neoplasms 20 | 142
Endometriosis 20 | 540
Reperfusion Injury 20 | 86
Brain disease 19 | 96
Diabetes Mellitus, Experimental 19 | 108
Diarrhea 19 | 253
Mental Depression 19 | 333
Multiple myeloma 19 | 1,332
Myocardial Infarction 19 | 151
Neoplastic Cell Transformation 19 | 89
Pancreatic Neoplasms 19 | 85
ovarian neoplasm 19 | 99
pituitary cancer 19 | 1,972
Coronary artery disease 18 | 268
Pancreatic Neoplasm 18 | 85
juvenile dermatomyositis 18 | 1,187

Tissue

Blood and immune system 121 | 16,909
Digestive Tract 121 | 17,369
Endocrine System 121 | 18,159
Female tissues 121 | 17,400
Liver and Pancreas 121 | 16,750
Nervous System 121 | 16,725
Respiratory system 121 | 16,393
Skin and soft tissues 121 | 17,230
Urinary Tract 121 | 16,678
Male tissues 120 | 17,142
Cardiovascular System 119 | 15,192

Target Family

Non-IDG 42 | 12,091
Kinase 41 | 634
Enzyme 24 | 4,145
Transcription Factor 12 | 1,400
Nuclear Receptor 2 | 48
Transporter 2 | 473

Compartment GO Term

Phosphatidylinositol 3-kinase ... 123 | 123
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rapamycin-insensitive companion of mTOR RICTOR Tbio Non-IDG -2.79454 597.0 440
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Tensin-1 TNS1 Tbio Non-IDG -2.74141 354.5 133
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
Eukaryotic translation initiation factor 2-alpha kinase 3 EIF2AK3 Tchem Kinase -3.05781 896.8 450