Development Level

Tbio 47 | 10,625
Tchem 31 | 1,890
Tclin 6 | 602
Tdark 4 | 7,003

IMPC Phenotype

preweaning lethality, complete... 4 | 633
decreased blood urea nitrogen ... 3 | 31
abnormal behavior 2 | 226
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
increased fasted circulating g... 2 | 68
increased mean corpuscular hem... 2 | 93
abnormal QRS complex 1 | 25
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 20
abnormal hindbrain development 1 | 24
abnormal kidney morphology 1 | 30
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal retina morphology 1 | 100
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased erythrocyte cell num... 1 | 43
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased memory-marker CD4-ne... 1 | 4
decreased threshold for audito... 1 | 32
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
hydrops fetalis 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased CD4-negative NK T ce... 1 | 4
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased exploration in new e... 1 | 56
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased vertical activity 1 | 18
long tibia 1 | 13
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
preweaning lethality, incomple... 1 | 260
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

ovarian cancer 60 | 8,491
medulloblastoma, large-cell 43 | 6,234
osteosarcoma 41 | 7,933
lung cancer 38 | 4,473
psoriasis 37 | 6,685
glioblastoma 35 | 5,572
Cancer 34 | 2,346
atypical teratoid / rhabdoid tumor 32 | 4,369
Carcinoma 25 | 2,147
Breast cancer 24 | 3,098
non-small cell lung cancer 24 | 2,798
oligodendroglioma 22 | 2,849
diabetes mellitus 21 | 1,663
ependymoma 21 | 2,514
Pick disease 20 | 1,893
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
adult high grade glioma 19 | 2,148
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
lung adenocarcinoma 19 | 2,714
lung carcinoma 19 | 2,844
malignant mesothelioma 19 | 3,163
invasive ductal carcinoma 18 | 2,950
pilocytic astrocytoma 18 | 3,086
primitive neuroectodermal tumor 18 | 3,031
subependymal giant cell astrocytoma 18 | 2,287
ulcerative colitis 18 | 2,087
interstitial cystitis 17 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
medulloblastoma 16 | 1,524
Multiple myeloma 15 | 1,327
astrocytic glioma 15 | 2,241
group 4 medulloblastoma 15 | 1,875
pediatric high grade glioma 15 | 2,712
astrocytoma 14 | 1,493
pancreatic cancer 14 | 2,300
Prostatic Neoplasms 12 | 471
colon cancer 12 | 1,475
ductal carcinoma in situ 12 | 1,745
group 3 medulloblastoma 12 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Rheumatoid Arthritis 11 | 1,170
breast carcinoma 11 | 1,614
Alzheimer's disease 10 | 644
Kidney disease 10 | 397
Obesity 10 | 616
pituitary cancer 10 | 1,972
Adenoma 9 | 165
Vascular disease 9 | 281
Waldenstrons macroglobulinemia 9 | 764
acute quadriplegic myopathy 9 | 1,157
adrenocortical carcinoma 9 | 1,427
cystic fibrosis 9 | 1,670
gastric carcinoma 9 | 832
spina bifida 9 | 1,064
Mammary Neoplasms 8 | 410
Stomach Neoplasms 8 | 282
aldosterone-producing adenoma 8 | 664
nasopharyngeal carcinoma 8 | 1,056
ovarian neoplasm 8 | 97
posterior fossa group A ependymoma 8 | 1,511
tuberculosis 8 | 1,563
Adenocarcinoma 7 | 115
Carcinoma of colon 7 | 32
Disease Progression 7 | 125
Heart disease 7 | 279
Liver carcinoma 7 | 217
Lung Neoplasms 7 | 171
cutaneous lupus erythematosus 7 | 1,056
dermatomyositis 7 | 966
juvenile dermatomyositis 7 | 1,189
posterior fossa group B ependymoma 7 | 1,530
sonic hedgehog group medulloblastoma 7 | 1,482
Colorectal Neoplasms 6 | 217
Diarrhea 6 | 155
Liver disease 6 | 219
Melanoma 6 | 261
Renal Cell Carcinoma 6 | 199
Schizophrenia 6 | 503
atypical teratoid/rhabdoid tumor 6 | 1,095
hepatocellular carcinoma 6 | 550
primary pancreatic ductal adenocarcinoma 6 | 1,271
tuberculosis and treatment for 6 months 6 | 686
Arthritis 5 | 248
Asthma 5 | 349
Colonic Neoplasms 5 | 126
Exanthem 5 | 39
Hypertension 5 | 293
IGA Glomerulonephritis 5 | 454
Lung disease 5 | 136
Osteoporosis 5 | 259
Parkinson's disease 5 | 364
Peripheral Neuropathy 5 | 303
Toxic encephalopathy 5 | 131
active Crohn's disease 5 | 918
acute myeloid leukemia 5 | 785
chronic lymphocytic leukemia 5 | 244
fibroadenoma 5 | 557
glioblastoma multiforme 5 | 347
hereditary spastic paraplegia 5 | 313
primary Sjogren syndrome 5 | 788

Tissue

Blood and immune system 87 | 17,994
Cardiovascular System 87 | 17,957
Digestive Tract 87 | 18,472
Endocrine System 87 | 18,511
Female tissues 87 | 18,646
Liver and Pancreas 87 | 18,135
Male tissues 87 | 17,968
Nervous System 87 | 18,560
Skin and soft tissues 87 | 18,114
Urinary Tract 87 | 18,443
Respiratory system 86 | 17,483

Target Family

Enzyme 67 | 4,146
Non-IDG 12 | 11,969
Kinase 6 | 634
Transcription Factor 2 | 1,400
Nuclear Receptor 1 | 48

Compartment GO Term

Phosphatase complex 88 | 88
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.25806 19000.3 3336
Leucine-rich repeat protein SHOC-2 SHOC2 Tbio Non-IDG -1.66913 50.1 144
Receptor-type tyrosine-protein phosphatase mu PTPRM Tbio Enzyme -1.82872 68.8 135
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform PPP2R2A Tchem Enzyme -1.27308 14.5 115
Calcineurin subunit B type 1 PPP3R1 Tbio Non-IDG -2.56314 362.9 113
TOX high mobility group box family member 4 TOX4 Tbio Transcription Factor -1.39348 25.8 94
CTD nuclear envelope phosphatase 1 CTDNEP1 Tbio Enzyme -0.84921 0.00000 99
M-phase inducer phosphatase 2 CDC25B Tchem Enzyme -2.31154 209.2 666
Protein phosphatase 1 regulatory subunit 15B PPP1R15B Tbio Enzyme -1.38755 23.9 74
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform PPP2R1A Tbio Enzyme -1.40388 25.3 259